The DOI matches its Crossref record; 86 of the 87 references it cites were found in a registry or an index.
Omega-3 fatty acids and inflammatory processes: from molecules to man
Open accessAbstract
Inappropriate, excessive or uncontrolled inflammation contributes to a range of human diseases. Inflammation involves a multitude of cell types, chemical mediators and interactions. The present article will describe nutritional and metabolic aspects of omega-6 (n-6) and omega-3 (n-3) fatty acids and explain the roles of bioactive members of those fatty acid families in inflammatory processes. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are n-3 fatty acids found in oily fish and fish oil supplements. These fatty acids are capable of partly inhibiting many aspects of inflammation including leucocyte chemotaxis, adhesion molecule expression and leucocyte–endothelial adhesive interactions, production of eicosanoids like prostaglandins and leukotrienes from the n-6 fatty acid arachidonic acid and production of pro-inflammatory cytokines. In addition, EPA gives rise to eicosanoids that often have lower biological potency than those produced from arachidonic acid, and EPA and DHA give rise to anti-inflammatory and inflammation resolving mediators called resolvins, protectins and maresins. Mechanisms underlying the anti-inflammatory actions of EPA and DHA include altered cell membrane phospholipid fatty acid composition, disruption of lipid rafts, inhibition of activation of the pro-inflammatory transcription factor nuclear factor κB so reducing expression of inflammatory genes and activation of the anti-inflammatory transcription factor peroxisome proliferator-activated receptor γ. Animal experiments demonstrate benefit from EPA and DHA in a range of models of inflammatory conditions. Human trials demonstrate benefit of oral n-3 fatty acids in rheumatoid arthritis and in stabilizing advanced atherosclerotic plaques. Intravenous n-3 fatty acids may have benefits in critically ill patients through reduced inflammation. The anti-inflammatory and inflammation resolving actions of EPA, DHA and their derivatives are of clinical relevance.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“These structural changes promote nitric oxide (NO) bioavailability and reduce endothelial expression of adhesion molecules such as VCAM-1 and ICAM-1, limiting monocyte adhesion and vascular inflammation [98].”
From Targeting triglycerides for cardiovascular risk reduction (2026) · cites this paper as [98]
Experimental — accuracy not yet measuredIn the citing paper
“Longchain omega-3 fatty acids—especially eicosapentaenoic acid and docosahexaenoic acid—modulate the expression of genes involved in metabolism and inflammation139”
From Chronic inflammation in the etiology of disease across the life span (2019) · cites this paper as [139]
In the citing paper
“having suboptimal omega-3 levels139, which impacts the resolution phase of inflammation”
From Chronic inflammation in the etiology of disease across the life span (2019) · cites this paper as [139]
In the citing paper
“Omega-3 PUFAs modulate inflammation.”
From Cardiovascular Impact of Nutritional Supplementation With Omega-3 Fatty Acids (2021) · cites this paper as [24]
In the citing paper
“They are involved in production of eicosanoids, prostaglandins, resolvins, protectins, and leukotrienes”
From Cardiovascular Impact of Nutritional Supplementation With Omega-3 Fatty Acids (2021) · cites this paper as [24]
In the citing paper
“Increased cellular membrane concentrations of EPA and DHA decrease the availability of arachidonic acid as a substrate for the synthesis of proinflammatory eicosanoids”
From Cardiovascular Impact of Nutritional Supplementation With Omega-3 Fatty Acids (2021) · cites this paper as [24]
In the citing paper
“EPA and DHA regulate T cell function”
From Cardiovascular Impact of Nutritional Supplementation With Omega-3 Fatty Acids (2021) · cites this paper as [24]
In the citing paper
“EPA decreases expression of the cyclooxygenase-2 gene”
From Cardiovascular Impact of Nutritional Supplementation With Omega-3 Fatty Acids (2021) · cites this paper as [24]
In the citing paper
“Omega-3 fatty acids (EPA and DHA) are widely recognized for their anti-inflammatory effects, primarily mediated through inhibition of NF-κB signaling102,103.”
From Emerging strategies in senotherapeutics: from broad-spectrum senolysis to precision reprogramming (2026) · cites this paper as [102]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Stary, H. C., Chandler, A. B., Dinsmore, R. E., Fuster, V., Glagov, S. K., Insull, W., Rosenfeld, M. E., Schwartz, C. J., Wagner, W. D., & Wissler, R. W. (1995) · Circulation · doi:10.1161/01.cir.92.5.1355 · Cited by 3,506
Glass, C. K., & Witztum, J. L. (2001) · Cell · doi:10.1016/s0092-8674(01)00238-0 · Cited by 3,094
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
Serhan, C. N., Chiang, N., & Van Dyke, T. E. (2008) · Nature Reviews Immunology · doi:10.1038/nri2294 · Cited by 2,932
Kliewer, S. A., Sundseth, S. S., Jones, S. A., Brown, P. J., Wisely, G. B., Koble, C. S., Devchand, P., Wahli, W., Willson, T. M., Lenhard, J. M., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.9.4318 · Cited by 2,164
Forman, B. M., Chen, J., & Evans, R. M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.9.4312 · Cited by 2,116
Endres, S., Ghorbani, R., Kelley, V. E., Georgilis, K., Lonnemann, G., van der Meer, J. W. M., Cannon, J. G., Rogers, T. S., Klempner, M. S., Weber, P. C., et al. (1989) · New England Journal of Medicine · doi:10.1056/nejm198902023200501 · Cited by 1,911
Marine omega-3 fatty acids and inflammatory processes: effects, mechanisms and clinical relevance
Calder, P. C. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.08.010 · Cited by 1,717
Self-citationPfeffer, K., Matsuyama, T., Kündig, T. M., Wakeham, A., Kishihara, K., Shahinian, A., Wiegmann, K., Ohashi, P. S., Krönke, M., & Mak, T. W. (1993) · Cell · doi:10.1016/0092-8674(93)90134-c · Cited by 1,677
Regulation of Immune Responses by Prostaglandin E2
Kaliński, P. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1101029 · Cited by 1,477
Lee, J. Y., Sohn, K. H., Rhee, S. H., & Hwang, D. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m011695200 · Cited by 1,299
Flagged first, then by citations
1 of the 87 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 501–600 of 1,002
Lindqvist, H. M., Gjertsson, I., Andersson, S. E. M., Calder, P. C., & Bärebring, L. (2019) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2019.08.004 · Cited by 13
Self-citationOmega-3 and Omega-6 fatty acids and risk of psychotic outcomes in the ALSPAC birth cohort
Thompson, A. D., Jones, H. J., Heron, J., Hibbeln, J. R., Sullivan, S. A., & Zammit, S. (2020) · Schizophrenia Research · doi:10.1016/j.schres.2020.09.018 · Cited by 15
Chen, J., Yi, C., Lu, C., Han, J., Shi, Q., Li, J., Zhou, J., & Su, X. (2021) · Journal of Functional Foods · doi:10.1016/j.jff.2021.104505 · Cited by 13
Firouzabadi, F. D., Jayedi, A., Asgari, E., Akbarzadeh, Z., Janbozorgi, N., Djafarian, K., & Shab‐Bidar, S. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.735174 · Cited by 13
Wijayabahu, A. T., Mickle, A. M., Mai, V., GARVAN, C. W., Glover, T. L., Cook, R. L., Zhao, J., Baum, M. K., Fillingim, R. B., & Sibille, K. T. (2022) · Nutrients · doi:10.3390/nu14020266 · Cited by 13
Chiang, E. I., Syu, J., Hung, H.-C., Rodriguez, R. L., Wang, W., Chiang, E.-R., Chiu, S., Chao, C.-Y., & Tang, F. (2022) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2022.109102 · Cited by 13
Gavzan, H., Hashemi, F., Babaei, J., & Sayyah, M. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.05.042 · Cited by 13
Reyes‐Hernández, C. G., Ramiro‐Cortijo, D., Rodríguez‐Rodríguez, P., Giambelluca, S., Simonato, M., González, M. D. C., de Pablo, Á. L. L., López-Giménez, M. R., Cogo, P. E., de Pipaón, M. S., et al. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19123863 · Cited by 13
Walker, M. E., Matthan, N. R., Goldbaum, A. A., Meng, H., Lamon‐Fava, S., Lakshman, S., Jang, S., Molokin, A., Solano-Aguilar, G. I., Urban, J. F., et al. (2019) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2019.04.013 · Cited by 13
Hustad, K. S., Rundblad, A., Ottestad, I. O., Christensen, J. J., Holven, K. B., & Ulven, S. M. (2020) · British Journal Of Nutrition · doi:10.1017/s0007114520002305 · Cited by 13
Carvalho, H. D. O., Gonçalves, D. E. S., Picanço, K. R. T., dos Santos, A. V. T. D. L. T., Lúcia, M., Hu, X., Fernandes, C. P., Ferreira, I. M., & Carvalho, J. C. T. (2020) · Inflammopharmacology · doi:10.1007/s10787-020-00754-y · Cited by 13
Zhou, J., Xue, Y., Liu, Y., Li, X., Tong, Z., & Li, W. (2020) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.12816 · Cited by 13
Neyra, A. L., Suárez, L., Muñoz, M. E., de Blas, A., de Valbuena, M. R., Garriga, M. J., Calvo‐Lerma, J., Ribes, C., Girón, R. M., Máiz, L., et al. (2020) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2020.102186 · Cited by 13
Passeri, E., Elkhoury, K., Garavito, M. C. J., Desor, F., Huguet, M., Soligot, C., Linder, M., Malaplate, C., Yen, F. T., & Arab‐Tehrany, E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111859 · Cited by 13
Udumula, M. P., Poisson, L., Dutta, I., Tiwari, N., Kim, S., Chinna-Shankar, J., Allo, G., Sakr, S., Hijaz, M., Munkarah, A. R., et al. (2022) · Cancers · doi:10.3390/cancers14061504 · Cited by 12
Targeting lipid metabolism in neurodegenerative diseases: From experimental to clinical
Long, J., Liu, S., Shi, Y., Zhang, C., Li, Q., & Ai, Q. (2025) · Metabolism · doi:10.1016/j.metabol.2025.156436 · Cited by 12
Paik, B., & Tong, L. H. T. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24044236 · Cited by 12
Distefano, A., Orlando, L., Giallongo, S., Tropea, E., Spampinato, M., Santisi, A., Longhitano, L., Parisi, G. F., Leonardi, S., Russo, A., et al. (2024) · Pharmaceuticals · doi:10.3390/ph17081066 · Cited by 14
Kaviani, E., Hajibabaie, F., Abedpoor, N., & Safavi, K. (2025) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.70092 · Cited by 14
Monmai, C., Jang, A.-Y., Kim, J., Lee, S.-M., You, S., Kang, S., & Park, W. J. (2020) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2007.07032 · Cited by 12
González‐Hedström, D., Priego, T., López‐Calderón, A., Amor, S., de la Fuente‐Fernández, M., Inarejos-García, A. M., Garcı́a-Villalón, Á. L., Martı́n, A. I., & Granado, M. (2020) · Nutrients · doi:10.3390/nu13010044 · Cited by 13
Öz, M., Uçak, İ., & Nayik, G. A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-89779-2.00004-1 · Cited by 13
Pascoal, L. B., Palma, B. B., Chaim, F. H. M., de Castro, M. M., Damázio, T. A., Franceschini, A. P. M. D. F., Milanski, M., Velloso, L. A., & Leal, R. F. (2022) · World Journal of Experimental Medicine · doi:10.5493/wjem.v12.i1.1 · Cited by 12
Maliszewska, K., Adamska-Patruno, E., Miniewska, K., Bauer, W., Mojsak, M. N., & Kretowski, A. J. (2022) · Scientific Reports · doi:10.1038/s41598-022-08125-z · Cited by 15
Emerging roles of polyunsaturated fatty acid synthesis pathway in colorectal cancer
Moon, Y.-A. (2023) · Animal Cells and Systems · doi:10.1080/19768354.2023.2189933 · Cited by 12
Bahadorpour, S., Hajhashemy, Z., Mohammadi, S., Mokhtari, E., Heidari, Z., & Saneei, P. (2023) · Scientific Reports · doi:10.1038/s41598-023-32510-x · Cited by 13
Caron, J. P., Gandy, J. C., Brown, J. L., & Sordillo, L. M. (2018) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2018.05.006 · Cited by 12
Fat-1 Transgene Is Associated With Improved Reproductive Outcomes
Hohos, N. M., Cho, K. J., Swindle, D. C., Allshouse, A. A., Rudolph, M. C., & Skaznik-Wikiel, M. E. (2018) · Endocrinology · doi:10.1210/en.2018-00723 · Cited by 12
Sehl, A., Couëdelo, L., Chamekh-Coelho, I., Vaysse, C., & Cansell, M. (2019) · British Journal Of Nutrition · doi:10.1017/s0007114519001491 · Cited by 12
Therapeutic implications of anti-inflammatory natural products in Alzheimer’s disease
Deb, S., Mazumder, M. K., Dutta, A., Phukan, B. C., Bhattacharya, P., Paul, R. K., & Borah, A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816992-6.00008-5 · Cited by 11
Garić, D., Sanctis, J. B. D., Dumut, D. C., Shah, J., Peña, M. J., Youssef, M., Petrof, B. J., Kopriva, F., Hanrahan, J. W., Hajdúch, M., et al. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2019.158538 · Cited by 12
Buoli, M., Caldiroli, L., Guenzani, D., Carnevali, G. S., Cesari, M., Turolo, S., Barkin, J. L., Messa, P., Agostoni, C. V., & Vettoretti, S. (2020) · Journal of Renal Nutrition · doi:10.1053/j.jrn.2020.08.017 · Cited by 12
Scannell, N., Villani, A., Moran, L., & Mantzioris, E. (2025) · Proceedings of the Nutrition Society · doi:10.1017/s0029665124007584 · Cited by 12
“…(DHA) partially inhibit a number of key aspects of inflammation including leucocyte chemotaxis, expression of adhesion molecules and leucocyte – endothelial adhesive interactions, production of eicosanoids and the up-regulation of pro-inflammatory cytokines, including TNF-α and IL-6 (154,155) .”
Compound green tea (CGT) regulates lipid metabolism in high-fat diet induced mice
Zhou, C., Hu, L., Mu, R., Mei, X., Wu, X., Wang, C., & Zhou, X. (2022) · RSC Advances · doi:10.1039/d2ra02831j · Cited by 11
Hulander, E., Sandström, T. Z., Rehnman, J. B., Law, L., Söderberg, S., & Forsblad‐d’Elia, H. (2023) · Arthritis Research & Therapy · doi:10.1186/s13075-023-03126-3 · Cited by 11
Péron, M., Gonzalvez, R., Hue, S., Soudant, P., Grand, F. L., Mazurais, D., & Vagner, M. (2024) · Marine Environmental Research · doi:10.1016/j.marenvres.2024.106456 · Cited by 11
Sachi, S., Jahan, M. P., Islam, P., Rafiq, K., & Islam, M. Z. (2024) · Veterinary and Animal Science · doi:10.1016/j.vas.2024.100349 · Cited by 11
Nutritional Support of Chronic Obstructive Pulmonary Disease
Simon, P., Török, É., Szalontai, K., Kari, B., Neuperger, P., Zavala, N., Kanizsai, I., Puskás, L. G., Török, S., & Szebeni, G. J. (2025) · Nutrients · doi:10.3390/nu17071149 · Cited by 14
Correani, A., Dell’Orto, V., Nobile, S., Antognoli, L., Marchionni, P., Giretti, I., Monachesi, C., Rondina, C., Palazzi, M. L., Biagetti, C., et al. (2020) · Pediatric Pulmonology · doi:10.1002/ppul.24938 · Cited by 11
Gao, X., Yi, X., Liu, Z., Dong, X., Xia, G., Zhang, X., & Shen, X. (2021) · Molecules · doi:10.3390/molecules26082328 · Cited by 11
Hayford, F. E. A., Dolman, R., Ozturk, M., Nienaber, A., Ricci, C., Loots, D. T., Brombacher, F., Blaauw, R., Smuts, C. M., Parihar, S. P., et al. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.695452 · Cited by 12
Susai, S. R., Mongan, D., Healy, C., Cannon, M. D., Nelson, B., Markulev, C., Schäfer, M. R., Berger, M., Mossaheb, N., Schlögelhofer, M., et al. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.09.018 · Cited by 11
The Impact of Omega-3 Supplements on Non-Surgical Periodontal Therapy: A Systematic Review
Miller, L. M., Piccinin, F. B., van der Velden, U., & Gomes, S. C. (2022) · Nutrients · doi:10.3390/nu14091838 · Cited by 30
Martínez, R., Mesas, C., Guzmán, A., Galisteo, M., López‐Jurado, M., Prados, J., Melguizo, C., Bermúdez, F., & Porres, J. M. (2022) · Food & Function · doi:10.1039/d2fo00672c · Cited by 14
Inflammation: A multifaceted and omnipresent phenomenon
Tyszkowski, R., & Mehrzad, R. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90960-0.00009-6 · Cited by 15
Zhu, X., An, W., Li, X., Zhou, B., & Li, H. (2022) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2022.104507 · Cited by 12
Yang, S., He, Q., Shi, L., & Wu, Y. (2022) · European Journal of Nutrition · doi:10.1007/s00394-022-03077-6 · Cited by 14
The Manipulation of the Lipid Mediator Metabolism as Adjunct Host-Directed Therapy in Tuberculosis
Nienaber, A., Hayford, F. E. A., Variava, E., Martinson, N. A., & Malan, L. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.623941 · Cited by 12
Pan, L., Zhou, Y., Yin, H., Hui, H., Guo, Y., & Xie, X. (2021) · Nutrition and Cancer · doi:10.1080/01635581.2021.1931365 · Cited by 11
Zorgetto-Pinheiro, V. A., Machate, D. J., Figueiredo, P. S., Marcelino, G., Hiane, P. A., Pott, A., Guimarães, R. D. C. A., & Bogo, D. (2022) · Journal of Medicinal Food · doi:10.1089/jmf.2021.0012 · Cited by 13
Aquatic foods in human health, nutrition, and overall welfare
Kumar, K. (2025) · Clinical Nutrition Open Science · doi:10.1016/j.nutos.2025.11.005 · Cited by 10
Balaji, M. V., Vashishth, R., & Das, U. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107155 · Cited by 15
Hawley, A. L., & Baum, J. (2023) · Nutrition Reviews · doi:10.1093/nutrit/nuad061 · Cited by 11
Odetayo, A. F., & Olayaki, L. A. (2024) · JBRA · doi:10.5935/1518-0557.20240033 · Cited by 10
Matthan, N. R., Lovato, L., Petersen, K. S., Kris‐Etherton, P. M., Sabaté, J., Rajaram, S., Li, Z., Reboussin, D. M., & Lichtenstein, A. H. (2024) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2024.08.002 · Cited by 10
D’Orazio, S., & Mattoscio, D. (2024) · Pharmaceuticals · doi:10.3390/ph17091185 · Cited by 12
Huang, S., Jiang, J., & Gong, H. (2024) · Scientific Reports · doi:10.1038/s41598-024-78486-0 · Cited by 11
The potential role of n-3 fatty acids and their lipid mediators on asthmatic airway inflammation
Tian, Y., Sun, J., Jiao, D., & Zhang, W. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1488570 · Cited by 10
Mendes, A. R., Madacussengua, O., Pestana, J. M., Martins, C. F., Spínola, M. P., Carvalho, D. F. P., Costa, Μ. M. R., Ferreira, P., Ferreira, J. I., Fontes, A. M., et al. (2025) · Poultry Science · doi:10.1016/j.psj.2025.105372 · Cited by 10
Comparative Analysis of the Antioxidant and Anti-Inflammatory Effects of Krill and Fish Oil
Sarıyer, E. T., Baş, M., & Yüksel, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157360 · Cited by 10
Quaglio, A. E. V., Cruz, V. M., de Almeida, L. D., Costa, C. A. R. A., & Stasi, L. C. D. (2020) · Planta Medica · doi:10.1055/a-1089-8342 · Cited by 10
Effect of salting procedures on quality of hake (Merluccius hubbsi) fillets
Marchetti, M. D., Gomez, P. L., Yeannes, M. I., & Loredo, A. B. G. (2021) · Heliyon · doi:10.1016/j.heliyon.2021.e07703 · Cited by 10
Mariane Lutz, R., Marcelo Arancibia, M., Papuzinski, C., & Stojanova, J. (2021) · Revista Española de Geriatría y Gerontología · doi:10.1016/j.regg.2021.08.003 · Cited by 11
Maghalian, M., Hasanzadeh, R., & Mirghafourvand, M. (2022) · Post Reproductive Health · doi:10.1177/20533691221083196 · Cited by 11
Campanari, D. D., Cipriano, U. G., Fraga‐Silva, T. F. D. C., Ramalho, L. N. Z., Ovídio, P. P., Júnior, A. A. J., Bonato, V. L. D., & Ferriolli, E. (2024) · Nutrients · doi:10.3390/nu16050634 · Cited by 11
Omega‐3 Polyunsaturated Fatty Acids as an Adjunct to Non‐Surgical Treatment of Periodontitis
Stańdo-Retecka, M., & Lewkowicz, N. (2019) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201800345 · Cited by 10
Patterns of Omega-3 and Omega-6 Fatty Acid Dietary Intake and Melanoma Thickness at Diagnosis
Mahamat‐Saleh, Y., Hughes, M. C. B., Miura, K., Malt, M. K., von Schuckmann, L. A., Khosrotehrani, K., Smithers, B. M., & Green, A. C. (2020) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-20-0319 · Cited by 10
Wesselink, A. K., Henn, B. C., Fruh, V., Orta, O. R., Weuve, J., Hauser, R. B., Williams, P. L., McClean, M. D., Sjödin, A., Bethea, T. N., et al. (2021) · Epidemiology · doi:10.1097/ede.0000000000001320 · Cited by 10
Pence, J., Martin, K. R., & Bloomer, R. J. (2021) · Health · doi:10.4236/health.2021.134027 · Cited by 13
Hansen, M. W., Ørn, S., Erevik, C. B., Bjørkavoll-Bergseth, M. F., Skadberg, Ø., Melberg, T. H., Aakre, K. M., & Kleiven, Ø. (2021) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-021-00437-1 · Cited by 11
Effect of Gum Acacia on the Intestinal Bioavailability of n-3 Polyunsaturated Fatty Acids in Rats
Couëdelo, L., Joseph, C., Abrous, H., Chamekh-Coelho, I., Vaysse, C., Baury, A., & Guillemet, D. (2022) · Biomolecules · doi:10.3390/biom12070975 · Cited by 10
Lu, F., Yang, Z., Li, Y., Hou, N., Yang, B., Lu, X., Bai, S., Wang, M., Zhang, X., Wang, H., et al. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113608 · Cited by 10
Zhang, W. (2021) · Nutrition Reviews · doi:10.1093/nutrit/nuab009 · Cited by 11
Use of Natural Components Derived from Oil Seed Plants for Treatment of Inflammatory Skin Diseases
Styrczewska, M., Żuk, M., Boba, A., Zalewski, I., & Kulma, A. (2019) · Current Pharmaceutical Design · doi:10.2174/1381612825666190716111700 · Cited by 9
Waits, C. M. K., Bower, A., Simms, K. N., Feldman, B. C., Kim, N., Sergeant, S., Chilton, F. H., VandeVord, P. J., Langefeld, C. D., & Rahbar, E. (2020) · Journal of Neurotrauma · doi:10.1089/neu.2019.6734 · Cited by 9
Quality Analysis of Canola and Mustard Oil Using Fluorescence Spectroscopy
Saleem, M. S., Ali, H., Bilal, M., Atta, B. M., & Ahmad, N. (2023) · Journal of Fluorescence · doi:10.1007/s10895-023-03185-4 · Cited by 9
Gharagozloo, A., Kheiri, F., Nasr, J., & Faghani, M. (2023) · Veterinary Medicine and Science · doi:10.1002/vms3.1296 · Cited by 9
Fish Oil Improves Offspring Metabolic Health of Paternal Obese Mice by Targeting Adipose Tissue
Lugo, M. I. P., Salas, M. L., Shrestha, A., & Ramalingam, L. (2024) · Biomolecules · doi:10.3390/biom14040418 · Cited by 9
Wu, Y., Rashidpour, A., & Metón, I. (2024) · Animals · doi:10.3390/ani14142118 · Cited by 9
Makangali, K., Tultabayeva, T., Zamaratskaia, G., Ospankulova, G., Tokysheva, G., Абжанова, Ш. А., Zhakupova, G., & Ergalikyzy, A. (2024) · Applied Sciences · doi:10.3390/app14219986 · Cited by 9
Roles and therapeutic opportunities of ω-3 long-chain polyunsaturated fatty acids in lung cancer
Luo, J., Peng, S., Jiang, Z., Wang, Q., Zhang, M., Zeng, Y., Yuan, Y., Xia, M., Hong, Z., Yan, Y., et al. (2024) · iScience · doi:10.1016/j.isci.2024.111601 · Cited by 11
Gut microbiota and atrial cardiomyopathy
Sun, T., Song, B., & Li, B. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1541278 · Cited by 10
Harnessing nutrients and natural products for sustainable drug development against aging
Ding, F., Yu, Y., Zhang, Y., Wei, S., Han, J. H., Li, Z., Jiang, H., Ryu, D., Park, W., Ha, K., et al. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1579266 · Cited by 11
Aging immunity: unraveling the complex nexus of diet, gut microbiome, and immune function
Babakhani, K., Kucinskas, A. L., Ye, X., Giles, E. D., & Sun, Y. (2025) · Immunometabolism · doi:10.1097/in9.0000000000000061 · Cited by 12
Okut, S., Ozan, M., Buzdağlı, Y., Uçar, H., İnaç, M. R., Han, M. T., Bayram, E., & Baygutalp, N. K. (2025) · Nutrients · doi:10.3390/nu17132088 · Cited by 20
Zhang, J., Tan, Z., Tian, Z., Zhao, M., Qian, S., Feng, H., Chang, Y., Hou, J., & Jiang, Z. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c04623 · Cited by 9
Sánchez, S. S., Quevedo, R. G., Fernandes, T. M., & da Fonseca, G. W. P. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1618360 · Cited by 12
Lifestyle implications of the paradox and management of oxidative stress in sperm
Patanè, G. T., Moreira, R., Russo, A., Pereira, M. D. L., Oliveira, P. F., Barreca, D., & Alves, M. G. (2025) · The Journal of Physiology · doi:10.1113/jp289694 · Cited by 9
Sustainable valorisation of fish processing byproducts through integrated biorefinery approaches
Haque, S. A., Jufaili, S. M. A., Islam, M. F., Hasan, M., Mamdouh-Lotfy, M., Rahman, M. S., & Al-Habsi, N. A. (2026) · Discover Food · doi:10.1007/s44187-026-00913-0 · Cited by 13
Beharry, K. D. A., Cai, C. L., Siddiqui, F., D’Agrosa, C., Zangaladze, A., Mustafa, G., Qadri, A., Duggan, T. J., & Aranda, J. V. (2020) · Nutrients · doi:10.3390/nu12071980 · Cited by 10
Maternal high-fat diet in mice alters immune regulation and lung function in the offspring
Losol, P., Mercken, L. P., Fisk, H. L., Calder, P. C., Holloway, J. W., & Torrens, C. (2020) · British Journal Of Nutrition · doi:10.1017/s0007114520004742 · Cited by 9
Self-citationZhu, Z., Wang, W., Zha, Y., Wang, X., Wang, L., Han, J., Zhang, J., & Lv, W. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.814953 · Cited by 9
Xu, W., Finitsis, D. J., Salner, A., & Judge, M. P. (2022) · Pain Management Nursing · doi:10.1016/j.pmn.2022.03.007 · Cited by 9
Pražnikar, Z. J., Novak, K. Š., Jontez, N. B., Petelin, A., Mohorko, N., & Kenig, S. (2023) · Scientific Reports · doi:10.1038/s41598-023-44233-0 · Cited by 13
Novel mustard oil/aloe vera gel microemuslions as potential biomaterials
Fares, M. M., & Radaydeh, S. K. (2024) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2024.124077 · Cited by 9
5-lipoxygenase-dependent biosynthesis of novel 20:4 n-3 metabolites with anti-inflammatory activity
Gagnon, K. J., Lefort, N., Poirier, S. J., Barnett, D. A., & Surette, M. E. (2018) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2018.10.005 · Cited by 9
Insulin-induced lipid body accumulation is accompanied by lipid remodelling in model mast cells
Aldan, J. T., Jansen, C., Speck, M. D., Maaetoft‐Udsen, K., Cordasco, E. A., Faiai, M., Shimoda, L. M. N., Greineisen, W. E., Turner, H. C., & Stokes, A. J. (2019) · Adipocyte · doi:10.1080/21623945.2019.1636624 · Cited by 9
Yan, S., Li, M., Yang, D., Pan, Y., Wang, C., Zhao, H., Li, B., & Cui, W. (2019) · Nutrition and Cancer · doi:10.1080/01635581.2019.1669673 · Cited by 9
Adipose Tissue in Health and Disease
Corona-Meraz, F.-I., Anda, J.-A. R.-D., Madrigal-Ruíz, P.-M., Diaz-Rubio, G. I., Castro-Albarrán, J., & Navarro-Hernández, R. E. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.90559 · Cited by 9
Ximenynic Acid Regulation of n-3 PUFA Content in Liver and Brain
Cai, F., Liu, Y. D., Hettiarachichi, D. S., Wang, F., Li, J., Sunderland, B., & Li, D. (2020) · Lifestyle Genomics · doi:10.1159/000502773 · Cited by 9
Metadata
- Authors
- Calder, P. C.
- Affiliations
- Southampton General Hospital (GB)
- Corresponding author
- Calder, Philip C.
- ORCID
- Calder, Philip C.
- Venue
- Biochemical Society Transactions
- Publisher
- Portland Press Ltd.
- Published
- 2017-09-12
- Volume
- 45
- Issue
- 5
- Pages
- 1105-1115
- ISSN
- 0300-5127 (ISSN-L)
- 1470-8752
- OpenAlex
- W2754394790
- Cited by
- 1,456
- References
- 87
- Citations by year
- 2026: 250 · 2025: 255 · 2024: 179 · 2023: 140 · 2022: 141 · 2021: 170 · 2020: 167 · 2019: 97 · 2018: 52 · 2017: 3
- FWCI
- 8.95
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Locations
- Biochemical Society Transactions (publishedVersion)
- PubMed (publishedVersion)
- ePrints Soton (University of Southampton) (submittedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Pharmacology (medical) › Inflammatory mediators and NSAID effects
- Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
- Keywords
- omega-3 fatty acids, omega-6 fatty acids, inflammation, eicosapentaenoic acid, docosahexaenoic acid, fish oil, resolvins, protectins, maresins, eicosanoids, arachidonic acid, leukotrienes, prostaglandins, inflammatory cytokines, nuclear factor-kappaB, PPARγ, lipid rafts, cell membrane phospholipids, rheumatoid arthritis, atherosclerosis, critically ill patients, anti-inflammatory mechanism
- MeSH terms
- Anti-Inflammatory Agents, Clinical Trials as Topic, Dietary Fats, Unsaturated, Docosahexaenoic Acids, Humans, Inflammation, Eicosapentaenoic Acid, Fatty Acids, Omega-3, Cytokines, Fatty Acids, Omega-6
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
