The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Pathogenic perspectives for the role of inflammation in diabetic nephropathy
Abstract
Diabetes and its complications have become a public health problem. One of the most important complications is diabetic nephropathy, which is nowadays the main cause of chronic renal failure. In spite of our greater understanding of this complication, the intimate mechanisms leading to the development and progression of renal injury are not well understood. New perspectives in activated innate immunity and inflammation appear to be relevant factors in the pathogenesis of diabetes. Moreover, different inflammatory molecules, including adipokines, Toll-like receptors, chemokines, adhesion molecules and pro-inflammatory cytokines, may be critical factors in the development of microvascular diabetic complications, including nephropathy. This new pathogenic perspective leads to important therapeutic considerations, with new pathogenic pathways becoming important therapeutic targets that can be translated into clinical treatments for diabetic nephropathy.
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Cited by
Neuroinflammation and the generation of neuropathic pain
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Immune responses in diabetic nephropathy: Pathogenic mechanisms and therapeutic target
Chen, J., Liu, Q., He, J., & Li, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.958790 · Cited by 164
Sitagliptin Prevents Inflammation and Apoptotic Cell Death in the Kidney of Type 2 Diabetic Animals
Marques, C., Mega, C., Gonçalves, A., Rodrigues-Santos, P., Teixeira-Lemos, E., Teixeira, F., Fontes-Ribeiro, C., Reis, F., & Fernandes, R. (2014) · Mediators of Inflammation · doi:10.1155/2014/538737 · Cited by 126
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Zhu, X., Cheng, Y.-Q., Du, L., Li, Y., Zhang, F., Guo, H., Liu, Y.-W., & Yin, X.-X. (2015) · Phytotherapy Research · doi:10.1002/ptr.5254 · Cited by 66
Metadata
- Authors
- Rivero, A., Mora, C., Muros, M., García, J., Herrera, H., & Navarro-González, J. F.
- Venue
- Clinical Science
- Publisher
- Portland Press Ltd.
- Published
- 2009-02-12
- Volume
- 116
- Issue
- 6
- Pages
- 479-492
- ISSN
- 0143-5221 (ISSN-L)
- 1470-8736
- OpenAlex
- W1996610877
- Cited by
- 190
- References
- 18
- FWCI
- 9.89
- Type
- journal article
- Language
- en
- Open access
- closed
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- Rivero, A., Mora, C., Muros, M., García, J., Herrera, H., & Navarro-González, J. F. (2009). Pathogenic perspectives for the role of inflammation in diabetic nephropathy. Clinical Science. https://doi.org/10.1042/cs20080394
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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