The DOI matches its Crossref record; 130 of the 130 references it cites were found in a registry or an index.
TGF-β/TGF-β receptor system and its role in physiological and pathological conditions
Open accessAbstract
The TGF-β (transforming growth factor-β) system signals via protein kinase receptors and Smad mediators to regulate a plethora of biological processes, including morphogenesis, embryonic development, adult stem cell differentiation, immune regulation, wound healing and inflammation. In addition, alterations of specific components of the TGF-β signalling pathway may contribute to a broad range of pathologies such as cancer, cardiovascular pathology, fibrosis and congenital diseases. The knowledge about the mechanisms involved in TGF-β signal transduction has allowed a better understanding of the disease pathogenicity as well as the identification of several molecular targets with great potential in therapeutic interventions.
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Citations
Cites
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
Shi, Y., & Massagué, J. (2003) · Cell · doi:10.1016/s0092-8674(03)00432-x · Cited by 5,857
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Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member
McPherron, A. C., Lawler, A. M., & Lee, S.-J. (1997) · Nature · doi:10.1038/387083a0 · Cited by 4,013
Massagué, J. (2008) · Cell · doi:10.1016/j.cell.2008.07.001 · Cited by 3,907
Metastasis: from dissemination to organ-specific colonization
Nguyen, D. X., Bos, P. D., & Massagué, J. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2622 · Cited by 2,649
(2016) · Lung Transplantation · doi:10.3109/9781439802571-25 · Cited by 2,157
Loeys, B. L., Chen, J., Neptune, E. R., Judge, D. P., Podowski, M., Holm, T., Meyers, J., Leitch, C. C., Katsanis, N., Sharifi, N., et al. (2005) · Nature Genetics · doi:10.1038/ng1511 · Cited by 1,795
Non-Smad pathways in TGF-β signaling
Zhang, Y. E. (2009) · Cell Research · doi:10.1038/cr.2008.328 · Cited by 1,749
Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child
Schuelke, M., Wagner, K. R., Stolz, L. E., Hübner, C., Riebel, T., Kömen, W., Braun, T., Tobin, J. F., & Lee, S.-J. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040933 · Cited by 1,399
TGFβ signalling: a complex web in cancer progression
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Landskron, G., De la Fuente, M., Thuwajit, P., Thuwajit, C., & Hermoso, M. A. (2014) · Journal of Immunology Research · doi:10.1155/2014/149185 · Cited by 1,765
Sennino, B., Ishiguro-Oonuma, T., Wei, Y., Naylor, R. M., Williamson, C. W., Bhagwandin, V., Tabruyn, S. P., You, W.-K., Chapman, H. A., Christensen, J. G., et al. (2012) · Cancer Discovery · doi:10.1158/2159-8290.cd-11-0240 · Cited by 408
Liby, K. T., & Sporn, M. B. (2012) · Pharmacological Reviews · doi:10.1124/pr.111.004846 · Cited by 405
Role of the TGF-β/BMP-7/Smad pathways in renal diseases
Meng, X.-M., Chung, A. C. K., & Lan, H. Y. (2013) · Clinical Science · doi:10.1042/cs20120252 · Cited by 354
Adipocyte-derived exosomal miRNAs: a novel mechanism for obesity-related disease
Ferrante, S. C., Nadler, E. P., Pillai, D. K., Hubal, M. J., Wang, Z., Wang, J. M., Gordish-Dressman, H., Koeck, E., Sevilla, S., Wiles, A. A., et al. (2015) · Pediatric Research · doi:10.1038/pr.2014.202 · Cited by 305
Metadata
- Authors
- Santibañez, J. F., Quintanilla, M., & Bernabeu, C.
- Venue
- Clinical Science
- Publisher
- Portland Press Ltd.
- Published
- 2011-05-27
- Volume
- 121
- Issue
- 6
- Pages
- 233-251
- ISSN
- 0143-5221 (ISSN-L)
- 1470-8736
- OpenAlex
- W2052147002
- Cited by
- 397
- References
- 130
- FWCI
- 14.34
- Type
- journal article
- Language
- en
- Open access
- green
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- Santibañez, J. F., Quintanilla, M., & Bernabeu, C. (2011). TGF-β/TGF-β receptor system and its role in physiological and pathological conditions. Clinical Science. https://doi.org/10.1042/cs20110086
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
