Calcineurin phosphatase in signal transduction: lessons from fission yeast

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Nuclear Export of NF-ATc Enhanced by Glycogen Synthase Kinase-3

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Genes to cells edited by Jun-ichi Tomizawa, Blackwell Science Ltd. Institutional: £218.00 (Europe), £242.00 (Rest of World), US$382.00 (USA and Canada). Individual: £65.00 (Europe), £72.00 (Rest of World), US$114.00 (USA and Canada) ISSN 1356 9597

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SIGNAL TRANSMISSION BETWEEN THE PLASMA MEMBRANE AND NUCLEUS OF T LYMPHOCYTES

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Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4

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Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition

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Calcineurin acts through the<i>CRZ1/TCN1</i>-encoded transcription factor to regulate gene expression in yeast

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Nuclear Accumulation of NFAT4 Opposed by the JNK Signal Transduction Pathway

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The protein phosphatase calcineurin is essential for NaCl tolerance of Saccharomyces cerevisiae.

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Tcn1p/Crz1p, a calcineurin-dependent transcription factor that differentially regulates gene expression in <i>Saccharomyces cerevisiae</i>

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Intramolecular Masking of Nuclear Import Signal on NF-AT4 by Casein Kinase I and MEKK1

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Calcineurin: From structure to function

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Calcium triggers calcineurin-dependent synaptic vesicle recycling in mammalian nerve terminals

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Protein phosphatase type 2B (calcineurin)‐mediated, FK506‐sensitive regulation of intracellular ions in yeast is an important determinant for adaptation to high salt stress conditions.

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Modulator binding protein. Bovine brain protein exhibiting the Ca2+-dependent association with the protein modulator of cyclic nucleotide phosphodiesterase.

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Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone.

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MSS4, a Phosphatidylinositol-4-phosphate 5-Kinase Required for Organization of the Actin Cytoskeleton in Saccharomyces cerevisiae *

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The Fission Yeast pmk1+ Gene Encodes a Novel Mitogen-Activated Protein Kinase Homolog Which Regulates Cell Integrity and Functions Coordinately with the Protein Kinase C Pathway

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Cloning of cDNAs Encoding Two Isoforms of 68-kDa Type I Phosphatidylinositol4-phosphate 5-Kinase

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Calcineurin, the Ca2+/Calmodulin-Dependent Protein Phosphatase, Is Essential in Yeast Mutants with Cell Integrity Defects and in Mutants That Lack a Functional Vacuolar H+-Atpase

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TheSaccharomyces cerevisiae genes (CMP1 andCMP2) encoding calmodulin-binding proteins homologous to the catalytic subunit of mammalian protein phosphatase 2B

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A calcineurin-like gene ppb1 + in fission yeast: mutant defects in cytokinesis, cell polarity, mating and spindle pole body positioning

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Phosphatidylinositol-4-phosphate 5-Kinase Localized on the Plasma Membrane Is Essential for Yeast Cell Morphogenesis

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Identification of Amino Acid Residues and Protein Kinases Involved in the Regulation of NFATc Subcellular Localization

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Two novel protein kinase C‐related genes of fission yeast are essential for cell viability and implicated in cell shape control.

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The Calcium/Calmodulin-dependent Protein Phosphatase Calcineurin Is the Major Elk-1 Phosphatase

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Role of calcineurin and Mpk1 in regulating the onset of mitosis in budding yeast

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pmp1+, a suppressor of calcineurin deficiency, encodes a novel MAP kinase phosphatase in fission yeast

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Spm1, a stress‐activated MAP kinase that regulates morphogenesis in S.pombe

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Stimulation of Elk1 Transcriptional Activity by Mitogen-activated Protein Kinases Is Negatively Regulated by Protein Phosphatase 2B (Calcineurin)

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Phosphatidylinositol 4-Phosphate 5-Kinase Its3 and Calcineurin Ppb1 Coordinately Regulate Cytokinesis in Fission Yeast

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The MAPK kinase Pek1 acts as a phosphorylation-dependent molecular switch

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cDNA cloning of a calcineurin B homolog in Saccharomyces cerevisiae

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Mkh1, a MEK Kinase Required for Cell Wall Integrity and Proper Response to Osmotic and Temperature Stress in Schizosaccharomyces pombe

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The identification of a gene family in the Saccharomyces cerevisiae ergosterol biosynthesis pathway

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Molecular genetic analysis of the calcineurin signaling pathways

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Genetic evidence for the functional redundancy of the calcineurin-and Mpk1-mediated pathways in the regulation of cellular events important for growth inSaccharomyces cerevisiae

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Its8, a Fission Yeast Homolog of Mcd4 and Pig-n, Is Involved in GPI Anchor Synthesis and Shares an Essential Function with Calcineurin in Cytokinesis

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The fission yeast STS5+ gene is required for maintenance of growth polarity and functionally interacts with protein kinase C and an osmosensing MAP-kinase pathway

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Regulation of Calcineurin Gene Expression in Schizosaccharomyces pombe

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Regulation of Phosphatidylinositol 4-Phosphate 5-Kinase fromSchizosaccharomyces pombe by Casein Kinase I

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Fission yeast sts1+ gene encodes a protein similar to the chicken lamin B receptor and is implicated in pleiotropic drug-sensitivity, divalent cation-sensitivity, and osmoregulation.

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Genetic Interaction Between Calcineurin and Type 2 Myosin and Their Involvement in the Regulation of Cytokinesis and Chloride Ion Homeostasis in Fission Yeast

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Lipid kinases are novel effectors of the GTPase Rac1

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Genetic evidence for the functional redundancy of the calcineurin- and Mpk1-mediated pathways in the regulation of cellular events important for growth in

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Phosphatidylinositol-4-phosphate 5-kinase Its3 and calcineurin Ppb1 coordinately regulate cytokinesis in fission yeast

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Regulation of Cell Cycle Progression by Calcium/Calmodulin-Dependent Pathways

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The <i>Cryptococcus neoformans</i> MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function

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Components of the Calcium-Calcineurin Signaling Pathway in Fungal Cells and Their Potential as Antifungal Targets

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Calcineurin as a multifunctional regulator: Unraveling novel functions in fungal stress responses, hyphal growth, drug resistance, and pathogenesis

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Zinc Finger Protein Prz1 Regulates Ca2+ but Not Cl− Homeostasis in Fission Yeast

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Localization and activity of the calcineurin catalytic and regulatory subunit complex at the septum is essential for hyphal elongation and proper septation in <i>Aspergillus fumigatus</i>

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Functional characterization of the Candida albicans CRZ1 gene encoding a calcineurin-regulated transcription factor

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Loss of Apm1, the μ1 Subunit of the Clathrin-Associated Adaptor-Protein-1 Complex, Causes Distinct Phenotypes and Synthetic Lethality with Calcineurin Deletion in Fission Yeast

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Atf1 Is a Target of the Mitogen-activated Protein Kinase Pmk1 and Regulates Cell Integrity in Fission Yeast

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Fission yeast cell wall biosynthesis and cell integrity signalling

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The diverse roles of calcium-binding protein regucalcin in cell biology: from tissue expression and signalling to disease

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Glucose Activates TORC2-Gad8 Protein via Positive Regulation of the cAMP/cAMP-dependent Protein Kinase A (PKA) Pathway and Negative Regulation of the Pmk1 Protein-Mitogen-activated Protein Kinase Pathway

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Phospholipid-Binding Protein Cts1 Controls Septation and Functions Coordinately with Calcineurin in Cryptococcus neoformans

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Ethanol stress stimulates the Ca2+-mediated calcineurin/Crz1 pathway in Saccharomyces cerevisiae

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Stress-activated Protein Kinase-mediated Down-Regulation of the Cell Integrity Pathway Mitogen-activated Protein Kinase Pmk1p by Protein Phosphatases

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Schizosaccharomyces pombe Pmr1p Is Essential for Cell Wall Integrity and Is Required for Polarized Cell Growth and Cytokinesis

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The Cell Surface Protein Geneecm33+Is a Target of the Two Transcription Factors Atf1 and Mbx1 and Negatively Regulates Pmk1 MAPK Cell Integrity Signaling in Fission Yeast

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Valproic Acid Affects Membrane Trafficking and Cell-Wall Integrity in Fission Yeast

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Calcineurin-Mediated Regulation of Hyphal Growth, Septation, and Virulence in Aspergillus fumigatus

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Negative Functional Interaction Between Cell Integrity MAPK Pathway and Rho1 GTPase in Fission Yeast

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The Fungal Cell Wall

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Calcineurin Orchestrates Hyphal Growth, Septation, Drug Resistance and Pathogenesis of Aspergillus fumigatus: Where Do We Go from Here?

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Dissecting the Roles of the Calcineurin Pathway in Unisexual Reproduction, Stress Responses, and Virulence in Cryptococcus deneoformans

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Pmr1, a P‐type ATPase, and Pdt1, an Nramp homologue, cooperatively regulate cell morphogenesis in fission yeast: The importance of Mn2+ homeostasis

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Paxillin-Mediated Recruitment of Calcineurin to the Contractile Ring Is Required for the Correct Progression of Cytokinesis in Fission Yeast

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Deletion mutants of AP‐1 adaptin subunits display distinct phenotypes in fission yeast

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P5A-Type ATPase Cta4p Is Essential for Ca2+ Transport in the Endoplasmic Reticulum of Schizosaccharomyces pombe

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Fingolimod (FTY720) Stimulates Ca2+/Calcineurin Signaling in Fission Yeast

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Macrophage colony‐stimulating factor‐dependent macrophage proliferation is mediated through a calcineurin‐independent but immunophilin‐dependent mechanism that mediates the activation of external regulated kinases

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Acremomannolipin A, the potential calcium signal modulator with a characteristic glycolipid structure from the filamentous fungus Acremonium strictum

Sugiura, R., Kita, A., Tsutsui, N., Muraoka, O., Hagihara, K., Umeda, N., Kunoh, T., Takada, H., & Hirose, D. (2012) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2012.08.085 · Cited by 22 · see citing works

NADPH-Cytochrome P450 Reductase Ccr1 Is a Target of Tamoxifen and Participates in Its Antifungal Activity via Regulating Cell Wall Integrity in Fission Yeast

Liu, Q., Guo, X., Jiang, G., Wu, G., Hao, M., Liu, K., Chen, S. E., Sakamoto, N., Kuno, T., Yao, F., et al. (2020) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00079-20 · Cited by 19 · see citing works

Genome-Wide Screening for Genes Associated with FK506 Sensitivity in Fission Yeast

Ma, Y., Jiang, W., Liu, Q., Ryuko, S., & Kuno, T. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023422 · Cited by 17 · see citing works

Plasma membrane damage repair is mediated by an acid sphingomyelinase in Entamoeba histolytica

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Structure of cyclophilin fromLeishmania donovaniat 1.97 Å resolution

Venugopal, V., Sen, B., Datta, A. K., & Banerjee, R. (2007) · Acta Crystallographica Section F Structural Biology and Crystallization Communications · doi:10.1107/s1744309106056351 · Cited by 13 · see citing works

The putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast

Nakazawa, N., Teruya, T., Sajiki, K., Kumada, K., Villar‐Briones, A., Arakawa, O., Takada, J., Saitoh, S., & Yanagida, M. (2018) · Journal of Cell Science · doi:10.1242/jcs.217331 · Cited by 13 · see citing works

Calmodulin Binding to Dfi1p Promotes Invasiveness of Candida albicans

Davis, T. R., Zucchi, P., & Kumamoto, C. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076239 · Cited by 12 · see citing works

Endosomal Trafficking Defects Can Induce Calcium-Dependent Azole Tolerance in Candida albicans

Luna-Tapia, A., Tournu, H., Peters, T. L., & Palmer, G. E. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01034-16 · Cited by 12 · see citing works

Negative feedback regulation of calcineurin-dependent Prz1 transcription factor by the CaMKK-CaMK1 axis in fission yeast

Barroso, E. C., Yance-Chávez, T., Kito, A., Sugiura, R., Gómez-Hierro, A., Giménez-Zaragoza, D., & Aligué, R. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku684 · Cited by 12 · see citing works

Novel motif in calcineurin catalytic subunit is required for septal localization of calcineurin in <i>Aspergillus fumigatus</i>

Juvvadi, P. R., Pemble, C. W., Ma, Y., & Steinbach, W. J. (2016) · FEBS Letters · doi:10.1002/1873-3468.12075 · Cited by 11 · see citing works

The Kin1 kinase and the calcineurin phosphatase cooperate to link actin ring assembly and septum synthesis in fission yeast

Cadou, A., Couturier, A., Goff, C. L., Xie, L., Paulson, J. R., & Goff, X. L. (2013) · Biology of the Cell · doi:10.1111/boc.201200042 · Cited by 10 · see citing works

Rae1-mediated nuclear export of Rnc1 is an important determinant in controlling MAPK signaling

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Two calcium sensor-activated kinases function in root hair growth

Fang, X., Liu, B., Kong, H., Zeng, J., Feng, Y., Xiao, C., Shao, Q., Huang, X., Wu, Y., Bao, A., et al. (2024) · PLANT PHYSIOLOGY · doi:10.1093/plphys/kiae365 · Cited by 8 · see citing works

Hyperbranching induced by cold‐shock or snow‐flake mutation in Neurospora crassa is prevented by addition of exogenous calcium

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Identification and characterization of a novel antifungal compound tubeimoside I targeting cell wall

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Imp2, the PSTPIP homolog in fission yeast, affects sensitivity to the immunosuppressant FK506 and membrane trafficking in fission yeast

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Guanosine Triphosphatase Activation Occurs Downstream of Calcineurin in Cardiac Hypertrophy

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Fission Yeast as a Model System for Studying Cancer Signaling and Drug Discovery: Discovery of ACA-28 as a Novel Inducer of ERK-dependent Apoptosis Reveals a New Cancer Therapy

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Case report: A novel PPP3CA truncating mutation within the regulatory domain causes severe developmental and epileptic encephalopathy in a Chinese patient

Li, J., & Cao, J. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.889167 · Cited by 2 · see citing works

SAGA complex subunit Spt20 involves in the calcineurin-mediated Cl- homeostasis in Schizosaccharomyces pombe

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Interacciones de la GTPasa Rho1 con la ruta de MAPKs de integridad celular y la fosfatasa calcineurina en la levadura de fisión Schizosaccharomyces pombe

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Quantitative proteomic analysis of chromatin-bound proteins in the fission yeast Schizosaccharomyces pombe

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The role of RNA granules as signaling hubs

Satoh, R., Hagihara, K., Kita, A., & Sugiura, R. (2016) · Folia Pharmacologica Japonica · doi:10.1254/fpj.147.340

Biological evidence of the protective role of regucalcin in breast cancer

Marques, R. (2016) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)

DOES CALCIUM INFLUX THROUGH T-TYPE CALCIUM CHANNEL INDUCE CARDIOMYOCYTE PROLIFERATION?

Wang, F. (2012) · TUScholarShare (Temple University)

Endosomal Trafficking as a Determinant of Antifungal Tolerance in the Pathogenic Fungus Candida albicans

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Función de la fosfatasa calcineurina en la citocinesis de Schizosaccharomyces pombe

Antón, V. A. (2019) · doi:10.14201/gredos.143511

Faculty Opinions recommendation of The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function.

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Current Awareness on Yeast

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Functional analysis of calcineurin-mediated signalling pathway using fission yeast as a model system.

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Calcium | Calcium Signaling: Calmodulin-Dependent Phosphatase

Klee, C. B., & Li, S. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-819460-7.00523-5

Calcium Signaling: Calmodulin-Dependent Phosphatase

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Calcineurin: Form and Function

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Calcineurin: Roles of the Ca2+/calmodulindependent protein phosphatase in diverse eukaryotes

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