The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Salmonella Pathogenicity Island 2
Open accessAbstract
Systemic infections by Salmonella enterica, such as typhoid fever, are a significant threat to human health. Recent studies indicate that the function of a type III secretion system encoded by Salmonella Pathogenicity Island 2 (SPI2) is central for the ability of S. enterica to cause systemic infections and for intracellular pathogenesis. This review summarizes approaches leading to the identification of SPI2, the molecular genetics and evolution of SPI2, and the current understanding of the regulation of gene expression. Recent studies have indicated that SPI2 is used by intracellular Salmonella to actively modify functions of the host cells. The role of SPI2 during pathogenesis of salmonellosis and current models regarding function will be discussed.
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Cites
Type III Protein Secretion Systems in Bacterial Pathogens of Animals and Plants
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Self-citationPathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution
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Self-citationIdentification of a pathogenicity island required for Salmonella survival in host cells.
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Cited by
Barthel, M., Hapfelmeier, S., Quintanilla-Martínez, L., Kremer, M., Rohde, M., Hogardt, M., Pfeffer, K., Rüssmann, H., & Hardt, W.-D. (2003) · Infection and Immunity · doi:10.1128/iai.71.5.2839-2858.2003 · Cited by 1,020
Pathogenicity Islands in BacterialPathogenesis
Schmidt, H., & Hensel, M. (2004) · Clinical Microbiology Reviews · doi:10.1128/cmr.17.1.14-56.2004 · Cited by 776
Self-citationSalmonella Interactions with Host Cells: Type III Secretion at Work
Galán, J. E. (2001) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.17.1.53 · Cited by 732
Persistent bacterial infections: the interface of the pathogen and the host immune system
Monack, D. M., Mueller, A., & Falkow, S. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro955 · Cited by 572
Population Dynamics of Salmonella enterica Serotypes in Commercial Egg and Poultry Production
Foley, S. L., Nayak, R., Hanning, I. B., Johnson, T. J., Han, J., & Ricke, S. C. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.00598-11 · Cited by 474
Metadata
- Authors
- Hensel, M.
- Venue
- Molecular Microbiology
- Publisher
- Wiley
- Published
- 2000-06
- Volume
- 36
- Issue
- 5
- Pages
- 1015-1023
- ISSN
- 0950-382X (ISSN-L)
- 1365-2958
- OpenAlex
- W2167730443
- Cited by
- 355
- References
- 40
- FWCI
- 32.02
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
