The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Transcriptome analysis of all two‐component regulatory system mutants of Escherichia coli K‐12
Abstract
Summary: We have systematically examined the mRNA profiles of 36 two‐component deletion mutants, which include all two‐component regulatory systems of Escherichia coli , under a single growth condition. DNA microarray results revealed that the mutants belong to one of three groups based on their gene expression profiles in Luria–Bertani broth under aerobic conditions: (i) those with no or little change; (ii) those with significant changes; and (iii) those with drastic changes. Under these conditions, the anaeroresponsive ArcB/ArcA system, the osmoresponsive EnvZ/OmpR system and the response regulator UvrY showed the most drastic changes. Cellular functions such as flagellar synthesis and expression of the RpoS regulon were affected by multiple two‐component systems. A high correlation coefficient of expression profile was found between several two‐component mutants. Together, these results support the view that a network of functional interactions, such as cross‐regulation, exists between different two‐component systems. The compiled data are avail‐able at our website ( http:ecoli.aist‐nara.ac.jpxpanalysis 2components ).
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Cited by
Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection
Baba, T., Ara, T., Hasegawa, M., Takai, Y., Okumura, Y., Baba, M., Datsenko, K. A., Tomita, M., Wanner, B. L., & Mori, H. (2006) · Molecular Systems Biology · doi:10.1038/msb4100050 · Cited by 7,858
Self-citationPathogenesis of Helicobacter pylori Infection
Kusters, J. G., van Vliet, A. H. M., & Kuipers, E. J. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.00054-05 · Cited by 2,526
Wolfe, A. J. (2005) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.69.1.12-50.2005 · Cited by 1,233
Stimulus Perception in Bacterial Signal-Transducing Histidine Kinases
Mascher, T., Helmann, J. D., & Unden, G. (2006) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00020-06 · Cited by 721
Yamamoto, K., Hirao, K., Oshima, T., Aiba, H., Utsumi, R., & Ishihama, A. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m410104200 · Cited by 444
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Metadata
- Authors
- Oshima, T., Aiba, H., Masuda, Y., Kanaya, S., Sugiura, M., Wanner, B. L., Mori, H., & Mizuno, T.
- Venue
- Molecular Microbiology
- Publisher
- Wiley
- Published
- 2002-10
- Volume
- 46
- Issue
- 1
- Pages
- 281-291
- ISSN
- 0950-382X (ISSN-L)
- 1365-2958
- OpenAlex
- W2147776446
- Cited by
- 375
- References
- 48
- FWCI
- 13.17
- Type
- journal article
- Language
- en
- Open access
- closed
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- Oshima, T., Aiba, H., Masuda, Y., Kanaya, S., Sugiura, M., Wanner, B. L., Mori, H., & Mizuno, T. (2002). Transcriptome analysis of all two‐component regulatory system mutants of Escherichia coli K‐12. Molecular Microbiology. https://doi.org/10.1046/j.1365-2958.2002.03170.x
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