The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Utility of antibodies against a 22 kD molecule of Dirofilaria immitis in the diagnosis of human pulmonary dirofilariasis
Open accessAbstract
To assess the characteristics of an ELISA test for the diagnosis of human pulmonary dirofilariasis, we studied the sera of 24 subjects with other helmintoses and of 37 patients suffering from non-parasitic focal lung diseases, comparing them with negative and positive sera. ELISA and Western blot with complete somatic antigen and ELISA with protein Di22 (specifically recognized in cases of lung dirofilariasis) were performed. With ELISA SA the false positive rate was 25% in cases with other parasitoses and 30% in cases with focal lung diseases. ELISA Di22 decreases this positivity levels. Only 2 cases with visceral larva migrans (8.3%) and a case with lung nodules metastatic from renal adenocarcinoma (2.7%) were positive. ELISA Di22 therefore greatly decreases the false positive rate of ELISA SA.
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“Seroepidemiological studies of residents of areas of endemicity reported higher rates of infection in a similar manner to those of canines of the same areas (1, 5, 13, 16, 17, 34).”
From Seroepidemiological Study of Canine and Human Dirofilariasis in the Endemic Region of Northern Serbia (2020) · cites this paper as [34]
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Cites
Human Pulmonary Dirofilariasis in the United States: a Critical Review
Ciferri, F. (1982) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1982.31.302 · Cited by 131
Seroepidemiological studies on human pulmonary dirofilariasis in Spain
Alvarez, A. M., Sánchez, M. C., Martin, J. M., & Martin, F. S. (1990) · Annals of Tropical Medicine and Parasitology · doi:10.1080/00034983.1990.11812459 · Cited by 51
Epidemiological studies on toxocariasis and visceral larva migrans in a zone of Western Spain
Garcia, L. C., Alvarez, A. M., & Martin, F. S. (1989) · Annals of Tropical Medicine and Parasitology · doi:10.1080/00034983.1989.11812395 · Cited by 50
A seroepidemiologic survey of human dirofilariosis in Western Spain.
Simón, F., Muro, A., Cordero, M., & Martin, J. (1991) · PubMed · Cited by 49
Tamashiro, W. K., Levy, D. A., Powers, K. G., & Scott, A. L. (1985) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1985.34.292 · Cited by 31
Enzyme-Linked Immunoelectrotransfer Blot (EITB)
Tsang, V. C. W., Bers, G., & Hancock, K. (1985) · Springer eBooks · doi:10.1007/978-1-4684-5012-5_22 · Cited by 28
Perera, L., Muro, A., Cordero, M., Villar, E., & Simón, F. (1994) · PubMed · Cited by 28
Are transient pulmonary solitary nodules a common event in human dirofilariosis?
Cordero, M., Muro, A., Sim�n, F., Tapia, J. I., & Espinoza, E. (1992) · The Clinical Investigator · doi:10.1007/bf00235528 · Cited by 27
Transient solitary pulmonary nodule caused by Dirofilaria immitis
Cordero, M., Munoz, M., Muro, A., & Simon, F. (1990) · European Respiratory Journal · doi:10.1183/09031936.93.03091070 · Cited by 27
Small Calcified Nodule: An Undescribed Radiologic Manifestation of Human Pulmonary Dirofilariasis
Cordero, M., Munoz, M. R., Muro, A., Simon, F., & Perera, M. L. (1992) · Journal of Infectious Diseases · doi:10.1093/infdis/165.2.398 · Cited by 26 · cited 2×
“Group B (positive controls) consisted of three patients with human pulmonary dirofilariosis detected by a previously reported case finding study (Cordero et al. 1990, 1992a).”
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Research works printed but not linked: 2
- Muro A Genchi C Cordero M & Simón F (1998) Human dirofilariosis: A review with special emphasis on the situation in the European Union.Parasitology Todayin press
- Perera L, 1994, Evaluation of a 22kDa Dirofilaria immitis antigen for the immunodiagnosis of human pulmonary dirofilariasis., Tropical Medicine and Parasitology, 45, 249
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Human and animal dirofilariasis: The emergence of a zoonotic mosaic
Simón, F., Siles-Lucas, M., Morchón, R., González-Miguel, J., Mellado, I., Carretón, E., & Montoya-Alonso, J. A. (2012) · Clinical Microbiology Reviews · doi:10.1128/cmr.00012-12 · Cited by 834
“In ELISAs, this protein exhibits 100% sensitivity and 90% specificity, with positive and negative predictive values of 75% and 100%, respectively (336).”
BackgroundChapter 4 Heartworm Disease in Animals and Humans
McCall, J. W., Genchi, C., Kramer, L. H., Guerrero, J., & Venco, L. (2008) · Advances in Parasitology · doi:10.1016/s0065-308x(08)00204-2 · Cited by 609
Human Dirofilariasis in the European Union
Muro, A., Genchi, C., Cordero, M., & Simón, F. (1999) · Parasitology Today · doi:10.1016/s0169-4758(99)01496-9 · Cited by 137
What is happening outside North America regarding human dirofilariasis?
Simón, F., López-Belmonte, J., Marcos-Atxutegi, C., Morchón, R., & Martín-Pacho, J. R. (2005) · Veterinary Parasitology · doi:10.1016/j.vetpar.2005.03.033 · Cited by 126
Self-citationHelminth-related Eosinophilia in African Immigrants, Gran Canaria
Pardo, J., Carranza‐Rodriguez, C., Muro, A., Ángel-Moreno, A., Martin, A.-M., Martin, T., Hernández-Cabrera, M., & Pérez-Arellano, J.-L. (2006) · Emerging infectious diseases · doi:10.3201/eid1210.060102 · Cited by 86
“ELISAs with crude extracts of adult Dirofilaria immitis adult worm antigens (AWA Di) (2), Schistosoma bovis worm antigens (3), Fasciola hepatica excretory/secretory antigens (4), and Trichinella spiralis L1 antigens (5) were used.”
Metadata
- Authors
- Perera, L., Pérez‐Arellano, J. L., Cordero, M., Simón, F., & Muro, A.
- Affiliations
- Universidad de Salamanca (ES)
- Corresponding author
- Muro, A.
- Venue
- Tropical Medicine & International Health
- Publisher
- Wiley
- Published
- 1998-02
- Volume
- 3
- Issue
- 2
- Pages
- 151-155
- ISSN
- 1360-2276 (ISSN-L)
- 1365-3156
- OpenAlex
- W2051191410
- Cited by
- 33
- References
- 13
- Citations by year
- 2026: 1 · 2020: 4 · 2018: 2 · 2017: 2 · 2016: 4 · 2014: 2 · 2012: 2
- FWCI
- 1.01
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Tropical Medicine & International Health (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
- Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
- Life Sciences › Immunology and Microbiology › Parasitology › Parasitic infections in humans and animals
- Keywords
- Dirofilaria immitis, ELISA, serological diagnosis, false positive rate, visceral larva migrans, Western blot
- MeSH terms
- Aged, Animals, Antibodies, Helminth, Dirofilaria immitis, Dirofilariasis, Enzyme-Linked Immunosorbent Assay, Female, Humans, Lung Diseases, Parasitic, Male, Middle Aged, Sensitivity and Specificity, Blotting, Western, Reproducibility of Results, Case-Control Studies
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