Cited by 423Blood Pressure and Hypertension StudiesChronic Kidney Disease and DiabetesSodium Intake and Health

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Hypertension Awareness, Treatment, and Control in Adults With CKD: Results From the Chronic Renal Insufficiency Cohort (CRIC) Study

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Muntner, Paul, Anderson, Amanda, Charleston, Jeanne, Chen, Zhen, Ford, Virginia, Makos, Gail, O'Connor, Andrew, Perumal, Kalyani, Rahman, Mahboob, Steigerwalt, Susan, Teal, Valerie, Townsend, Raymond, Weir, Matthew, Wright, Jackson T.·2010·American Journal of Kidney Diseases

DOI 10.1053/j.ajkd.2009.09.014PMC PMC2866514

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Abstract

Background A low rate of blood pressure control has been reported in patients with chronic kidney disease (CKD). These data were derived from population-based samples with a low rate of CKD awareness.Study design Cross-sectional.Setting & participants Data from the baseline visit of the Chronic Renal Insufficiency Cohort (CRIC) Study (n = 3,612) were analyzed. Participants with an estimated glomerular filtration rate of 20-70 mL/min/1.73 m(2) were identified from physician offices and review of laboratory databases.Outcomes Prevalence and awareness of hypertension, treatment patterns, control rates, and factors associated with hypertension control.Measurements Following a standardized protocol, blood pressure was measured 3 times by trained staff, and hypertension was defined as systolic blood pressure > or =140 mm Hg and/or diastolic blood pressure > or =90 mm Hg and/or self-reported antihypertensive medication use. Patients' awareness and treatment of hypertension were defined using self-report, and 2 levels of hypertension control were evaluated: systolic/diastolic blood pressure <140/90 and <130/80 mm Hg.Results The prevalence of hypertension was 85.7%, and 98.9% of CRIC participants were aware of this diagnosis and 98.3% were treated with medications, whereas 67.1% and 46.1% had hypertension controlled to <140/90 and <130/80 mm Hg, respectively. Of CRIC participants with hypertension, 15%, 25%, 26%, and 32% were using 1, 2, 3, and > or =4 antihypertensive medications, respectively. After multivariable adjustment, older patients, blacks, and those with higher urinary albumin excretion were less likely, whereas participants using angiotensin-converting enzyme inhibitors and angiotensin receptor blockers were more likely to have controlled their hypertension to <140/90 and <130/80 mm Hg.Limitations Data were derived from a single study visit.Conclusions Despite almost universal hypertension awareness and treatment in this cohort of patients with CKD, rates of hypertension control were suboptimal.

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Authors: Muntner, P., Anderson, A., Charleston, J., Chen, Z., Ford, V., Makos, G., O'Connor, A., Perumal, K., Rahman, M., Steigerwalt, S., Teal, V., Townsend, R., Weir, M., & Wright, J. T.
Affiliations: University of Alabama at Birmingham (US)
University of Pennsylvania (US)
University of Maryland, Baltimore (US)
National Institutes of Health (US)
University of Illinois Chicago (US)
University Hospitals Cleveland Medical Center (US)
St. John Medical Center (US)
Case Western Reserve University (US)
Corresponding author: Muntner, Paul
ORCID: Muntner, Paul
Anderson, Amanda
Charleston, Jeanne
Chen, Zhen
Rahman, Mahboob
Teal, Valerie
Townsend, Raymond
Wright, Jackson T.
Venue: American Journal of Kidney Diseases
Publisher: Elsevier BV
Published: 2010-03
Volume: 55
Issue: 3
Pages: 441-451
ISSN: 0272-6386 (ISSN-L)
DOI: 10.1053/j.ajkd.2009.09.014
PMC: PMC2866514
OpenAlex: W2096512601
Cited by: 423
References: 16
Citations by year: 2026: 10 · 2025: 34 · 2024: 32 · 2023: 45 · 2022: 34 · 2021: 35 · 2020: 33 · 2019: 40 · 2018: 32 · 2017: 23 · 2016: 20 · 2015: 19 · 2014: 13 · 2013: 16 · 2012: 17
FWCI: 7.55
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: American Journal of Kidney Diseases (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health
National Institute of Diabetes and Digestive and Kidney Diseases (5U01DK06102, U01DK060990, 5U01 DK60980, T32DK007785, T32DK060455, K01DK064860, U01DK060984, U01DK060902, U01DK060980, U01DK060963, U01DK061021, U01DK061028)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
Keywords: hypertension, chronic kidney disease, blood pressure control, hypertension awareness, antihypertensive medication use, ACE inhibitors, angiotensin receptor blockers, urinary albumin excretion, Chronic Renal Insufficiency Cohort Study, older adults, racial disparities
MeSH terms: Adult, Aged, Chronic Disease, Female, Humans, Hypertension, Kidney Diseases, Male, Middle Aged, Renal Insufficiency, Young Adult

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Hypertension Awareness, Treatment, and Control in Adults With CKD: Results From the Chronic Renal Insufficiency Cohort (CRIC) Study

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