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Primary Prophylaxis of Spontaneous Bacterial Peritonitis Delays Hepatorenal Syndrome and Improves Survival in Cirrhosis
Open accessAbstract
Background & aims Norfloxacin is highly effective in preventing spontaneous bacterial peritonitis recurrence in cirrhosis, but its role in the primary prevention of this complication is uncertain.Methods Patients with cirrhosis and low protein ascitic levels (<15 g/L) with advanced liver failure (Child-Pugh score > or = 9 points with serum bilirubin level > or = 3 mg/dL) or impaired renal function (serum creatinine level > or = 1.2 mg/dL, blood urea nitrogen level > or = 25 mg/dL, or serum sodium level < or = 130 mEq/L) were included in a randomized controlled trial aimed at comparing norfloxacin (35 patients) vs placebo (33 patients) in the primary prophylaxis of spontaneous bacterial peritonitis. The main end points of the trial were 3-month and 1-year probability of survival. Secondary end points were 1-year probability of development of spontaneous bacterial peritonitis and hepatorenal syndrome.Results Norfloxacin administration reduced the 1-year probability of developing spontaneous bacterial peritonitis (7% vs 61%, P < .001) and hepatorenal syndrome (28% vs 41%, P = .02), and improved the 3-month (94% vs 62%, P = .003) and the 1-year (60% vs 48%, P = .05) probability of survival compared with placebo.Conclusions Primary prophylaxis with norfloxacin has a great impact in the clinical course of patients with advanced cirrhosis. It reduces the incidence of spontaneous bacterial peritonitis, delays the development of hepatorenal syndrome, and improves survival.
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“Similar to norfloxacin, rifaximin has been noted to increased survival in patients with advanced liver cirrhosis in several small-scale trials92–95.”
From The gut microbiome and liver cancer: mechanisms and clinical translation (2017) · cites this paper as [92]
In the citing paper
“Clinical trials in patients with advanced cirrhosis have shown that long-term use of orally administered norfloxacin is safe, produces a marked reduction of gram-negative bacteria in the faecal microbiota109, reduces the 1-year probability of developing spontaneous bacterial peritonitis and hepatorenal syndrome and improves 3-month survival92.”
From The gut microbiome and liver cancer: mechanisms and clinical translation (2017) · cites this paper as [92]
In the citing paper
“Clinical trials in patients with advanced cirrhosis have shown that long-term use of orally administered norfloxacin is safe, produces a marked reduction of gram-negative bacteria in the faecal microbiota109, reduces the 1-year probability of developing spontaneous bacterial peritonitis and hepatorenal syndrome and improves 3-month survival92.”
From The gut microbiome and liver cancer: mechanisms and clinical translation (2017) · cites this paper as [92]
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“Moreover, several small-scale clinical studies have suggested that antibiotics such as norfloxacin and rifaximin increase survival in patients with liver cirrhosis92–95.”
From The gut microbiome and liver cancer: mechanisms and clinical translation (2017) · cites this paper as [92]
In the citing paper
“Clinical trials in patients with advanced cirrhosis have shown that long-term use of orally administered norfloxacin is safe, produces a marked reduction of gram-negative bacteria in the faecal microbiota109, reduces the 1-year probability of developing spontaneous bacterial peritonitis and hepatorenal syndrome and improves 3-month survival92.”
From The gut microbiome and liver cancer: mechanisms and clinical translation (2017) · cites this paper as [92]
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Cites
Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis
Arroyo, V., Ginès, P., Gerbes, A. L., Dudley, F. J., Geñtilini, P., Laffi, G., Reynolds, T. B., Ring‐Larsen, H., & Schölmerich, J. (1996) · Hepatology · doi:10.1002/hep.510230122 · Cited by 1,694
Self-citationSort, P., Navasa, M., Arroyo, V., Aldeguer, X., Planas, R., Ruíz-del-Árbol, L., Castells, L., Vargas, V., Soriano, G., Guevara, M., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199908053410603 · Cited by 1,636
Self-citationDiagnosis, treatment and prophylaxis of spontaneous bacterial peritonitis: a consensus document
Rimola, A., García–Tsao, G., Navasa, M., Piddock, L. J. V., Planas, R., Bernard‐Chabert, B., & Inadomi, J. M. (2000) · Journal of Hepatology · doi:10.1016/s0168-8278(00)80201-9 · Cited by 1,058
Self-citationFernández, J., Navasa, M., Gómez, J., Colmenero, J., Vila, J., Arroyo, V., & Rodés, J. (2002) · Hepatology · doi:10.1053/jhep.2002.30082 · Cited by 954
Self-citationIncidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites
Ginés, À., Escorsell, À., Ginès, P., Saló, J., Jiménez, W., Inglada, L., Navasa, M., Clària, J., Rimola, A., Arroyo, V., et al. (1993) · Gastroenterology · doi:10.1016/0016-5085(93)90031-7 · Cited by 874
Self-citationGinés, P., Rimola, A., Planas, R., Vargas, V., Marco, F., Almela, M., Forne, M., Miranda, M. L., Llach, J., Salmerón, J. M., et al. (1990) · Hepatology · doi:10.1002/hep.1840120416 · Cited by 627
Self-citationFollo, A., Llovet, J. M., Navasa, M., Planas, R., Forns, X., Francitorra, A., Rimola, A., Gassull, M. A., Arroyo, V., & Rodés, J. (1994) · Hepatology · doi:10.1002/hep.1840200619 · Cited by 597
Self-citationCirculatory function and hepatorenal syndrome in cirrhosis†
Ruíz-del-Árbol, L., Monescillo, A., Arocena, C., Valer, P., Ginès, P., Moreira, V., Milicua, J. M., Jiménez, W., & Arroyo, V. (2005) · Hepatology · doi:10.1002/hep.20766 · Cited by 584
Self-citationRuíz-del-Árbol, L., Urmán, J., Fernández, J., González, M., Navasa, M., Monescillo, A., Albillos, A., Jiménez, W., & Arroyo, V. (2003) · Hepatology · doi:10.1053/jhep.2003.50447 · Cited by 496
Self-citationLlach, J., Ginès, P., Arroyo, V., Rimola, A., Titó, L., Badalamenti, S., Jiménez, W., Gaya, J., Rivera, F., & Rodés, J. (1988) · Gastroenterology · doi:10.1016/0016-5085(88)90441-6 · Cited by 457
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Flagged first, then by citations
2 of the 36 references couldn’t be matched to a known paper.
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EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis
Angeli, P., Bernardi, M., Villanueva, C., Francoz, C., Mookerjee, R. P., Trebicka, J., Krag, A. A., Laleman, W., & Ginès, P. (2018) · Journal of Hepatology · doi:10.1016/j.jhep.2018.03.024 · Cited by 3,033
Self-citationTsochatzis, E. A., Bosch, J., & Burroughs, A. K. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60121-5 · Cited by 1,892
(2010) · Journal of Hepatology · doi:10.1016/j.jhep.2010.05.004 · Cited by 1,738
Arvaniti, V., D’Amico, G., Fede, G., Manousou, P., Tsochatzis, E. A., Pleguezuelo, M., & Burroughs, A. K. (2010) · Gastroenterology · doi:10.1053/j.gastro.2010.06.019 · Cited by 1,179
Management of adult patients with ascites due to cirrhosis
Runyon, B. A. (2009) · Hepatology · doi:10.1002/hep.22853 · Cited by 986
Bacterial infections in cirrhosis: A position statement based on the EASL Special Conference 2013
Jalan, R., Fernandez, J., Wiest, R., Schnabl, B., Moreau, R., Angeli, P., Stadlbauer, V., Gustot, T., Bernardi, M., Canton, R., et al. (2014) · Journal of Hepatology · doi:10.1016/j.jhep.2014.01.024 · Cited by 906
Self-citationFreedberg, D. E., Kim, L. S., & Yang, Y. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.01.031 · Cited by 933
Biggins, S. W., Angeli, P., García–Tsao, G., Ginès, P., Ling, S. C., Nadim, M. K., Wong, F. S.-H., & Kim, W. R. (2021) · Hepatology · doi:10.1002/hep.31884 · Cited by 865
Self-citationGinès, P., & Schrier, R. W. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0809139 · Cited by 836
Self-citationToll‐like receptors and adaptor molecules in liver disease: Update†
Seki, E., & Brenner, D. A. (2008) · Hepatology · doi:10.1002/hep.22306 · Cited by 722
Liver — guardian, modifier and target of sepsis
Strnad, P., Tacke, F., Koch, A., & Trautwein, C. (2017) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2016.168 · Cited by 692
Guidelines on the management of ascites in cirrhosis
Aithal, G. P., Palaniyappan, N., China, L., Härmälä, S., Macken, L., Ryan, J. M., Wilkes, E. A., Moore, K., Leithead, J. A., Hayes, P. C., et al. (2021) · Gut · doi:10.1136/gutjnl-2020-321790 · Cited by 680
Acute-on chronic liver failure
Jalan, R., Ginès, P., Olson, J. C., Mookerjee, R. P., Moreau, R., García–Tsao, G., Arroyo, V., & Kamath, P. S. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.06.026 · Cited by 674
Self-citationAcute kidney injury in cirrhosis
García–Tsao, G., Parikh, C. R., & Viola, A. (2008) · Hepatology · doi:10.1002/hep.22605 · Cited by 663
The gut microbiome and liver cancer: mechanisms and clinical translation
Yu, L.-X., & Schwabe, R. F. (2017) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2017.72 · Cited by 634
Bernardi, M., Moreau, R., Angeli, P., Schnabl, B., & Arroyo, V. (2015) · Journal of Hepatology · doi:10.1016/j.jhep.2015.07.004 · Cited by 645
Self-citationFernández, J., Acevedo, J., Castro, M., Garcia, O., de Lope, C. R., Roca, D., Pavesi, M., Sola, E., Moreira, L., Silva, A., et al. (2012) · Hepatology · doi:10.1002/hep.25532 · Cited by 620
Self-citationHuman serum albumin, systemic inflammation, and cirrhosis
Arroyo, V., García‐Martínez, R., & Salvatella, X. (2014) · Journal of Hepatology · doi:10.1016/j.jhep.2014.04.012 · Cited by 561
Self-citationBacterial Infections, Sepsis, and Multiorgan Failure in Cirrhosis
Tandon, P., & García–Tsao, G. (2008) · Seminars in Liver Disease · doi:10.1055/s-2008-1040319 · Cited by 549
Complications of Proton Pump Inhibitor Therapy
Vaezi, M. F., Yang, Y., & Howden, C. W. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.04.047 · Cited by 484
Gustot, T., Durand, F., Lebrec, D., Vincent, J., & Moreau, R. (2009) · Hepatology · doi:10.1002/hep.23264 · Cited by 445
Acute-on-chronic liver failure in cirrhosis
Arroyo, V., Moreau, R., Kamath, P. S., Jalan, R., Ginès, P., Nevens, F., Fernández, J., To, U. K., García–Tsao, G., & Schnabl, B. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.41 · Cited by 450
Self-citationEvidence-based clinical practice guidelines for Liver Cirrhosis 2020
Yoshiji, H., Nagoshi, S., Akahane, T., Asaoka, Y., Ueno, Y., Ogawa, K., Kawaguchi, T., Kurosaki, M., Sakaida, I., Shimizu, M., et al. (2021) · Journal of Gastroenterology · doi:10.1007/s00535-021-01788-x · Cited by 462
Immune Dysfunction and Infections in Patients With Cirrhosis
Bonnel, A. R., Bunchorntavakul, C., & Reddy, K. R. (2011) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2011.02.031 · Cited by 395
Spontaneous bacterial peritonitis: recent guidelines and beyond
Wiest, R., Krag, A. A., & Gerbes, A. (2011) · Gut · doi:10.1136/gutjnl-2011-300779 · Cited by 384
Management of bacterial infections in cirrhosis
Fernández, J., & Gustot, T. (2012) · Journal of Hepatology · doi:10.1016/s0168-8278(12)60002-6 · Cited by 382
Self-citationThe role of lipopolysaccharide/toll-like receptor 4 signaling in chronic liver diseases
Soares, J., Pimentel‐Nunes, P., Roncon‐Albuquerque, R., & Leite-Moreira, A. F. (2010) · Hepatology International · doi:10.1007/s12072-010-9219-x · Cited by 378
Portal Hypertension and Its Complications
Sanyal, A. J., Bosch, J., Blei, A. T., & Arroyo, V. (2008) · Gastroenterology · doi:10.1053/j.gastro.2008.03.007 · Cited by 360
Self-citationAcute-on-chronic liver failure
Bernal, W. E., Jalan, R., Quaglia, A., Simpson, K. J., Wendon, J. A., & Burroughs, A. K. (2015) · The Lancet · doi:10.1016/s0140-6736(15)00309-8 · Cited by 336
Toll-like receptors as targets in chronic liver diseases
Mencin, A. M., Kluwe, J., & Schwabe, R. F. (2009) · Gut · doi:10.1136/gut.2008.156307 · Cited by 340
Evidence-based clinical practice guidelines for liver cirrhosis 2015
Fukui, H., Saito, H., Ueno, Y., Uto, H., Obara, K., Sakaida, I., Shibuya, A., Seike, M., Nagoshi, S., Segawa, M., et al. (2016) · Journal of Gastroenterology · doi:10.1007/s00535-016-1216-y · Cited by 307
Management of the critically ill patient with cirrhosis: A multidisciplinary perspective
Nadim, M. K., Durand, F., Kellum, J. A., Levitsky, J., O’Leary, J. G., Karvellas, C. J., Bajaj, J. S., Davenport, A., Jalan, R., Angeli, P., et al. (2015) · Journal of Hepatology · doi:10.1016/j.jhep.2015.10.019 · Cited by 301
Self-citationRenal failure and cirrhosis: A systematic review of mortality and prognosis
Fede, G., D’Amico, G., Arvaniti, V., Tsochatzis, E. A., Germani, G., Georgiadis, D., Morabito, A., & Burroughs, A. K. (2011) · Journal of Hepatology · doi:10.1016/j.jhep.2011.10.016 · Cited by 282
Ginès, P., Solà, E., Angeli, P., Wong, F., Nadim, M. K., & Kamath, P. S. (2018) · Nature Reviews Disease Primers · doi:10.1038/s41572-018-0022-7 · Cited by 260
Self-citationBellot, P., Francés, R., & Such, J. M. (2012) · Liver International · doi:10.1111/liv.12021 · Cited by 255
Self-citationIntensive care of the patient with cirrhosis
Olson, J. C., Wendon, J. A., Kramer, D. J., Arroyo, V., Jalan, R., García–Tsao, G., & Kamath, P. S. (2011) · Hepatology · doi:10.1002/hep.24622 · Cited by 252
Self-citationGarcía–Tsao, G., & Lim, J. K. (2009) · The American Journal of Gastroenterology · doi:10.1038/ajg.2009.191 · Cited by 250
Wong, F. S.-H., O’Leary, J. G., Reddy, K. R., Patton, H. M., Kamath, P. S., Fallon, M. B., García–Tsao, G., Subramanian, R., Malik, R., Maliakkal, B. J., et al. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.08.051 · Cited by 248
Mookerjee, R. P., Pavesi, M., Thomsen, K. L., Mehta, G., Macnaughtan, J., Bendtsen, F., Coenraad, M., Sperl, J., Gines, P., Moreau, R., et al. (2016) · Journal of Hepatology · doi:10.1016/j.jhep.2015.10.018 · Cited by 248
Self-citationBOYER, T. D., Sanyal, A. J., García–Tsao, G., Blei, A. T., Carl, D. E., Bexon, A. S., & Teuber, P. (2010) · Journal of Hepatology · doi:10.1016/j.jhep.2010.11.020 · Cited by 247
β‐Blockers protect against spontaneous bacterial peritonitis in cirrhotic patients: a meta‐analysis
Senzolo, M., Cholongitas, E., Burra, P., Leandro, G., Thalheimer, U., Patch, D., & Burroughs, A. K. (2009) · Liver International · doi:10.1111/j.1478-3231.2009.02038.x · Cited by 241
Hepatorenal syndrome: pathophysiology, diagnosis, and management
Simonetto, D. A., Ginès, P., & Kamath, P. S. (2020) · BMJ · doi:10.1136/bmj.m2687 · Cited by 237
Self-citationBacterial infections in cirrhosis: A critical review and practical guidance
Bunchorntavakul, C., Chamroonkul, N., & Chavalitdhamrong, D. (2016) · World Journal of Hepatology · doi:10.4254/wjh.v8.i6.307 · Cited by 227
Salerno, F., Guevara, M., Bernardi, M., Moreau, R., Wong, F. S.-H., Angeli, P., García–Tsao, G., & Lee, S. S. (2010) · Liver International · doi:10.1111/j.1478-3231.2010.02272.x · Cited by 213
Vlachogiannakos, J., Viazis, N., Vasianopoulou, P., Vafiadis, I., Karamanolis, D. G., & Ladas, S. D. (2013) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.12070 · Cited by 206
Pathogenesis and Treatment of Hepatorenal Syndrome
Arroyo, V., Fernández, J., & Ginès, P. (2008) · Seminars in Liver Disease · doi:10.1055/s-2008-1040323 · Cited by 207
Self-citationAntibiotic prophylaxis in cirrhosis: Good and bad
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Self-citationDever, J. B., & Sheikh, M. Y. (2015) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13172 · Cited by 204
Evidence‐based clinical practice guidelines for liver cirrhosis 2020
Yoshiji, H., Nagoshi, S., Akahane, T., Asaoka, Y., Ueno, Y., Ogawa, K., Kawaguchi, T., Kurosaki, M., Sakaida, I., Shimizu, M., et al. (2021) · Hepatology Research · doi:10.1111/hepr.13678 · Cited by 204
Gut-liver axis in liver cirrhosis: How to manage leaky gut and endotoxemia
Fukui, H. (2015) · World Journal of Hepatology · doi:10.4254/wjh.v7.i3.425 · Cited by 201
Leithead, J., Rajoriya, N., Tehami, N., Hodson, J. A., Gunson, B. K., Tripathi, D., & Ferguson, J. (2014) · Gut · doi:10.1136/gutjnl-2013-306502 · Cited by 190
The challenges of multi-drug-resistance in hepatology
Fernández, J., Bert, F., & Nicolas-Chanoine, M.-H. (2016) · Journal of Hepatology · doi:10.1016/j.jhep.2016.08.006 · Cited by 187
Self-citationCarrión, J. A., Martínez‐Bauer, E., Crespo, G., Ramírez, S., Pérez‐del‐Pulgar, S., García‐Valdecasas, J. C., Navasa, M., & Forns, X. (2008) · Journal of Hepatology · doi:10.1016/j.jhep.2008.11.015 · Cited by 184
Self-citationdu Plessis, J., Vanheel, H., Janssen, C., Roos, L., Slavík, T., Stivaktas, P. I., Nieuwoudt, M., van Wyk, S. G., Vieira, W. A., Pretorius, E., et al. (2013) · Journal of Hepatology · doi:10.1016/j.jhep.2013.01.038 · Cited by 178
Bajaj, J. S., Ananthakrishnan, A. N., Hafeezullah, M., Zadvornova, Y., Dye, A., McGinley, E. L., Saeian, K., Heuman, D. M., Sanyal, A. J., & Hoffmann, R. G. (2009) · The American Journal of Gastroenterology · doi:10.1038/ajg.2009.615 · Cited by 174
Morando, F., Maresio, G., Piano, S. S., Fasolato, S., Cavallin, M., Romano, A., Rosi, S., Gola, E., Frigo, A. C., Stanco, M., et al. (2013) · Journal of Hepatology · doi:10.1016/j.jhep.2013.03.010 · Cited by 170
Infections complicating cirrhosis
Piano, S. S., Brocca, A., Mareso, S., & Angeli, P. (2018) · Liver International · doi:10.1111/liv.13645 · Cited by 172
Francés, R., Zapater, P., González-Navajas, J. M., Muñoz, C., Caño, R., Moreu, R., Pascual, S., Bellot, P., Pérez‐Mateo, M., & Such, J. M. (2008) · Hepatology · doi:10.1002/hep.22083 · Cited by 168
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APASL consensus statements and management algorithms for hepatitis C virus infection
Omata, M., Kanda, T., Yu, M., Yokosuka, O., Lim, S. G., Jafri, W., Tateishi, R., Hamid, S. S., Chuang, W., Chutaputti, A., et al. (2012) · Hepatology International · doi:10.1007/s12072-012-9342-y · Cited by 164
Zapater, P., Francés, R., González-Navajas, J. M., de la Hoz, M. A., Moreu, R., Pascual, S., Monfort, D., Montoliu, S., Vila, C., Escudero, A., et al. (2008) · Hepatology · doi:10.1002/hep.22564 · Cited by 165
Self-citationCharlton, M., Wall, W. J., OJO, A. O., Ginès, P., Textor, S. C., Shihab, F. S., Marotta, P., Cantarovich, M., Eason, J. D., Wiesner, R. H., et al. (2009) · Liver Transplantation · doi:10.1002/lt.21877 · Cited by 159
Self-citationToll-like Receptor 4 and Hepatic Fibrogenesis
Pradere, J.-P., Troeger, J., Dapito, D., Mencin, A., & Schwabe, R. (2010) · Seminars in Liver Disease · doi:10.1055/s-0030-1255353 · Cited by 158
Kanwal, F., Kramer, J. R., Buchanan, P. M., Asch, S. M., Assioun, Y., Bacon, B. R., Li, J., & El‐Serag, H. B. (2012) · Gastroenterology · doi:10.1053/j.gastro.2012.03.038 · Cited by 156
Terg, R., Fassio, E., Guevara, M., Cartier, M., Longo, C., Lucero, R. S., Landeira, C., Romero, G., Domínguez, N., Muñoz, A., et al. (2008) · Journal of Hepatology · doi:10.1016/j.jhep.2008.01.024 · Cited by 153
Acute-on-chronic liver failure in patients with alcohol-related liver disease
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Risk factors and outcome of bacterial infections in cirrhosis
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Acute Kidney Injury After Liver Transplantation
Durand, F., Francoz, C., Asrani, S. K., Khemichian, S., Pham, T., Sung, R. S., Genyk, Y., & Nadim, M. K. (2018) · Transplantation · doi:10.1097/tp.0000000000002305 · Cited by 148
Revision and update on clinical practice guideline for liver cirrhosis
Suk, K. T., Baik, S. K., Yoon, J., Cheong, J. Y., Paik, Y. H., Lee, C. H., Kim, Y. S., Lee, J. W., Kim, D. J., Cho, S. W., et al. (2012) · The Korean Journal of Hepatology · doi:10.3350/kjhep.2012.18.1.1 · Cited by 142
Levitsky, J., O’Leary, J. G., Asrani, S. K., Sharma, P., Fung, J. J., Wiseman, A. C., & Niemann, C. U. (2016) · American Journal of Transplantation · doi:10.1111/ajt.13765 · Cited by 142
Marciano, S., Díaz, J. M., Dirchwolf, M., & Gadano, A. C. (2019) · Hepatic Medicine Evidence and Research · doi:10.2147/hmer.s164250 · Cited by 149
Schmidt, M., Barritt, A. S., Orman, E. S., & Hayashi, P. H. (2015) · Gastroenterology · doi:10.1053/j.gastro.2015.01.032 · Cited by 141
Leithead, J., Ferguson, J., Bates, C. M., Davidson, J. S., Lee, A. J., Bathgate, A. J., Hayes, P. C., & Simpson, K. J. (2008) · Gut · doi:10.1136/gut.2008.154120 · Cited by 142
Ascites: Diagnosis and Management
Hou, W., & Sanyal, A. J. (2009) · Medical Clinics of North America · doi:10.1016/j.mcna.2009.03.007 · Cited by 141
Cirrhotic ascites review: Pathophysiology, diagnosis and management
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New therapeutic paradigm for patients with cirrhosis
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Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III)
Reiberger, T., Püspök, A., Schoder, M., Baumann‐Durchschein, F., Bucsics, T., Datz, C., Dolak, W., Ferlitsch, A., Finkenstedt, A., Graziadei, I. W., et al. (2017) · Wiener klinische Wochenschrift · doi:10.1007/s00508-017-1262-3 · Cited by 137
Appenrodt, B., Grünhage, F., Gentemann, M., Thyssen, L., Sauerbruch, T., & Lammert, F. (2009) · Hepatology · doi:10.1002/hep.23440 · Cited by 133
Reappraising the spectrum of AKI and hepatorenal syndrome in patients with cirrhosis
Velez, J. C. Q., Therapondos, G., & Juncos, L. A. (2019) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0218-4 · Cited by 131
Spontaneous bacterial peritonitis
Koulaouzidis, A., Bhat, S. K., & Saeed, A. A. (2009) · World Journal of Gastroenterology · doi:10.3748/wjg.15.1042 · Cited by 130
Francoz, C., Durand, F., Kahn, J. A., Genyk, Y., & Nadim, M. K. (2019) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.12451018 · Cited by 129
Renal and circulatory dysfunction in cirrhosis: Current management and future perspectives
Solà, E., & Ginès, P. (2010) · Journal of Hepatology · doi:10.1016/j.jhep.2010.08.001 · Cited by 127
Self-citationShah, N. K., Dhar, D. K., Mohamed, F. E. Z. A., Habtesion, A., Davies, N. A., Jover‐Cobos, M., Macnaughtan, J., Sharma, V., Damink, S. W. M. O., Mookerjee, R. P., et al. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2011.11.024 · Cited by 127
Shah, N. K., Mohamed, F. E. Z. A., Jover‐Cobos, M., Macnaughtan, J., Davies, N. A., Moreau, R., Paradis, V., Moore, K. P., Mookerjee, R. P., & Jalan, R. (2012) · Liver International · doi:10.1111/liv.12047 · Cited by 124
S3-Leitlinie „Aszites, spontan bakterielle Peritonitis, hepatorenales Syndrom”
Gerbes, A. L., Gülberg, V., Sauerbruch, T., Wiest, R., Appenrodt, B., Bahr, M., Dollinger, M., Rossle, M. P., & Schepke, M. (2011) · Zeitschrift für Gastroenterologie · doi:10.1055/s-0031-1273405 · Cited by 124
Soriano, G., Castellote, J., Álvarez, C., Girbau, A., Gordillo, J., Baliellas, C., Casas, M., Pons, C., Román, E. M., Maisterra, S., et al. (2009) · Journal of Hepatology · doi:10.1016/j.jhep.2009.10.012 · Cited by 122
Self-citationGiuffrè, M., Campigotto, M., Campisciano, G., Comar, M., & Crocè, L. S. (2020) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00161.2019 · Cited by 122
Tao, J., Li, S., Gan, R., Zhao, C., Meng, X., & Li, H. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1555789 · Cited by 120
Portal hypertension: pathophysiology, diagnosis and management
Bloom, S., Kemp, W. W., & Lubel, J. S. (2014) · Internal Medicine Journal · doi:10.1111/imj.12590 · Cited by 118
Acute Kidney Injury in Patients with Cirrhosis
Russ, K. B., Stevens, T. M., & Singal, A. K. (2015) · Journal of Clinical and Translational Hepatology · doi:10.14218/jcth.2015.00015 · Cited by 118
Pathogenesis and management of hepatorenal syndrome in patients with cirrhosis
Angeli, P., & Merkel, C. (2008) · Journal of Hepatology · doi:10.1016/j.jhep.2008.01.010 · Cited by 118
Fernández, J., Angeli, P., Trebicka, J., Merli, M., Gustot, T., Alessandria, C., Aagaard, N. K., Gottardi, A. D., Welzel, T. M., Gerbes, A. L., et al. (2019) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2019.07.055 · Cited by 118
Self-citationAcute kidney injury in acute-on-chronic liver failure: where does hepatorenal syndrome fit?
Davenport, A., Sheikh, M., Lamb, E. J., Agarwal, B., & Jalan, R. (2017) · Kidney International · doi:10.1016/j.kint.2017.04.048 · Cited by 115
Carvedilol use is associated with improved survival in patients with liver cirrhosis and ascites
Sinha, R., Lockman, K. A., Mallawaarachchi, N., Robertson, M. C., Plevris, J. N., & Hayes, P. C. (2017) · Journal of Hepatology · doi:10.1016/j.jhep.2017.02.005 · Cited by 115
Ascites and Spontaneous Bacterial Peritonitis
Runyon, B. A. (2011) · Wiley eBooks · doi:10.1002/9781119950509.ch17 · Cited by 113
Gut-liver axis signaling in portal hypertension
Simbrunner, B., Mandorfer, M., Trauner, M., & Reiberger, T. (2019) · World Journal of Gastroenterology · doi:10.3748/wjg.v25.i39.5897 · Cited by 113
Min, Y. W., Lim, K. S., Min, B., Gwak, G., Paik, Y., Choi, M. S., Lee, J., Kim, J. J., Koh, K. C., Paik, S. W., et al. (2014) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12875 · Cited by 110
Surgery in the Patient with Liver Disease
Muilenburg, D. J., Singh, A., Torzilli, G., & Khatri, V. P. (2009) · Medical Clinics of North America · doi:10.1016/j.mcna.2009.05.008 · Cited by 110
Sepsis in alcohol-related liver disease
Gustot, T., Fernández, J., Szabó, G., Albillos, A., Louvet, A., Jalan, R., Moreau, R., & Moreno, C. (2017) · Journal of Hepatology · doi:10.1016/j.jhep.2017.06.013 · Cited by 108
Self-citationTerlipressin and albumin for type-1 hepatorenal syndrome associated with sepsis
Rodríguez, E., Elia, C., Solà, E., Barreto, R., Graupera, I., Andrealli, A., Pereira, G., Poca, M., Sánchez‐Delgado, J., Guevara, M., et al. (2014) · Journal of Hepatology · doi:10.1016/j.jhep.2013.12.032 · Cited by 109
Self-citation
Metadata
- Authors
- Fernández, J., Navasa, M., Planas, R., Montoliu, S., Monfort, D., Soriano, G., Vila, C., Pardo, A., Quintero, E., Vargas, V., Such, J., Ginès, P., & Arroyo, V.
- Affiliations
- Hospital Clínic de Barcelona (ES)
- Hospital Universitari Germans Trias i Pujol (ES)
- Hospital de Sant Pau (ES)
- Hospital Del Mar (ES)
- Hospital Universitario de Canarias (ES)
- Corresponding author
- Navasa, Miquel
- ORCID
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2007-09
- Volume
- 133
- Issue
- 3
- Pages
- 818-824
- ISSN
- 0016-5085 (ISSN-L)
- OpenAlex
- W2012746560
- Cited by
- 709
- References
- 36
- Citations by year
- 2026: 6 · 2025: 13 · 2024: 23 · 2023: 37 · 2022: 28 · 2021: 43 · 2020: 39 · 2019: 42 · 2018: 42 · 2017: 37 · 2016: 34 · 2015: 55 · 2014: 48 · 2013: 31 · 2012: 46
- FWCI
- 30.85
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Hepatology › Liver Disease and Transplantation
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Sepsis Diagnosis and Treatment
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Keywords
- spontaneous bacterial peritonitis, primary prophylaxis, norfloxacin, hepatorenal syndrome, liver cirrhosis, survival, renal dysfunction, antibiotic prophylaxis
- MeSH terms
- Aged, Anti-Infective Agents, Double-Blind Method, Female, Hepatorenal Syndrome, Humans, Liver Cirrhosis, Male, Middle Aged, Norfloxacin, Peritonitis, Risk Factors, Survival Analysis, Antibiotic Prophylaxis
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