The DOI matches its Crossref record; 148 of the 148 references it cites were found in a registry or an index.
Beyond Gene Discovery in Inflammatory Bowel Disease: The Emerging Role of Epigenetics
Open accessAbstract
In the past decade, there have been fundamental advances in our understanding of genetic factors that contribute to the inflammatory bowel diseases (IBDs) Crohn’s disease and ulcerative colitis. The latest international collaborative studies have brought the number of IBD susceptibility gene loci to 163. However, genetic factors account for only a portion of overall disease variance, indicating a need to better explore gene-environment interactions in the development of IBD. Epigenetic factors can mediate interactions between the environment and the genome; their study could provide new insight into the pathogenesis of IBD. We review recent progress in identification of genetic factors associated with IBD and discuss epigenetic mechanisms that could affect development and progression of IBD.
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Self-citation
Cited by
Understanding and Preventing the Global Increase of Inflammatory Bowel Disease
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The IBD interactome: an integrated view of aetiology, pathogenesis and therapy
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Interactions between Intestinal Microbiota and Host Immune Response in Inflammatory Bowel Disease
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Metadata
- Authors
- Ventham, N. T., Kennedy, N. A., Nimmo, E. R., & Satsangi, J.
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2013-08
- Volume
- 145
- Issue
- 2
- Pages
- 293-308
- ISSN
- 0016-5085 (ISSN-L)
- OpenAlex
- W2162217523
- Cited by
- 320
- References
- 148
- FWCI
- 20.03
- Type
- journal article
- Language
- en
- Open access
- green
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- Ventham, N. T., Kennedy, N. A., Nimmo, E. R., & Satsangi, J. (2013). Beyond Gene Discovery in Inflammatory Bowel Disease: The Emerging Role of Epigenetics. Gastroenterology. https://doi.org/10.1053/j.gastro.2013.05.050
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
