The DOI matches its Crossref record; 567 of the 567 references it cites were found in a registry or an index.
Nutrients, Foods, and Colorectal Cancer Prevention
Open accessAbstract
Diet has an important role in the development of colorectal cancer. In the past few decades, findings from extensive epidemiologic and experimental investigations have linked consumption of several foods and nutrients to the risk of colorectal neoplasia. Calcium, fiber, milk, and whole grains have been associated with a lower risk of colorectal cancer, and red meat and processed meat have been associated with an increased risk. There is substantial evidence for the potential chemopreventive effects of vitamin D, folate, fruits, and vegetables. Nutrients and foods also may interact, as a dietary pattern, to influence colorectal cancer risk. Diet likely influences colorectal carcinogenesis through several interacting mechanisms. These include the direct effects on immune responsiveness and inflammation, and the indirect effects of overnutrition and obesity-risk factors for colorectal cancer. Emerging evidence also implicates the gut microbiota as an important effector in the relationship between diet and cancer. Dietary modification therefore has the promise of reducing colorectal cancer incidence.
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“Over the past few decades, migration studies and prospective cohort studies have established the important effects of diet and lifestyle in the development of CRC.3”
From Influence of the Gut Microbiome, Diet, and Environment on Risk of Colorectal Cancer (2020) · cites this paper as [3]
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Garrett, W. S. (2015) · Science · doi:10.1126/science.aaa4972 · Cited by 1,404
Self-citationThe Intestinal Microbiota in Colorectal Cancer.
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Influence of the Gut Microbiome, Diet, and Environment on Risk of Colorectal Cancer
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Metadata
- Authors
- Song, M., Garrett, W. S., & Chan, A. T.
- Affiliations
- Harvard University (US)
- Brigham and Women's Hospital (US)
- Corresponding author
- Chan, Andrew T.
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2015-05
- Volume
- 148
- Issue
- 6
- Pages
- 1244-1260.e16
- ISSN
- 0016-5085 (ISSN-L)
- PMC
- PMC4409470
- OpenAlex
- W2164272712
- Cited by
- 700
- References
- 567
- Citations by year
- 2026: 39 · 2025: 66 · 2024: 88 · 2023: 81 · 2022: 84 · 2021: 75 · 2020: 74 · 2019: 62 · 2018: 46 · 2017: 39 · 2016: 30 · 2015: 14
- FWCI
- 6.19
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Cancer Institute (R01CA137178, R01CA154426)
- National Institute of Diabetes and Digestive and Kidney Diseases (K24DK098311)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Oncology › Colorectal Cancer Screening and Detection
- Health Sciences › Medicine › Oncology › Cancer Risks and Factors
- Keywords
- colorectal cancer prevention, diet and cancer risk, colorectal neoplasia, calcium, dietary fiber, whole grains, milk, red meat, processed meat, vitamin D, folic acid, fruits and vegetables, dietary habits, colorectal carcinogenesis, inflammation, obesity, gut microbiota, chemoprevention
- MeSH terms
- Animals, Antioxidants, Diet, Energy Metabolism, Feeding Behavior, Humans, Nutritional Status, Nutritive Value, Risk Factors, Vitamins, Colorectal Neoplasms, Anticarcinogenic Agents, Risk Assessment, Gastrointestinal Tract, Host-Pathogen Interactions, Microbiota, Protective Factors
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