Understanding fragile X syndrome
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Relative strengths in Fragile X syndrome include receptive language skills, visual memory, acquisition of factual information, imitation skills and gestalt processing.
“Relative strengths include receptive language skills, visual memory, acquisition of factual information, imitation skills and gestalt processing (Berry-Kravis et al., 2002).”
From Oxytocin and vasopressin systems in genetic syndromes and neurodevelopmental disorders (2014) · cites this paper as Berry-Kravis et al., 2002
Individuals with Fragile X syndrome exhibit deficits in visuospatial tasks, quantitative skills, short-term and working memory, expressive language skills, sequential processing and executive function.
“FXS individuals exhibit deficits in visuospatial tasks, quantitative skills, short-term and working memory, expressive language skills, sequential processing and executive function (Berry-Kravis et al., 2002; Cornish et al., 1999; Freund and Reiss, 1991; Hall et al., 2012; Kwon et al., 2001; Maes et al., 1994).”
From Oxytocin and vasopressin systems in genetic syndromes and neurodevelopmental disorders (2014) · cites this paper as Berry-Kravis et al., 2002
Of individuals with Fragile X syndrome and autistic behaviors, 15-40% of males and a few females meet the diagnostic criteria for ASD.
“Of the individuals with FXS and autistic behaviors, 15–40% of males and a few females meet the diagnostic criteria for ASD (Berry-Kravis et al., 2002).”
From Oxytocin and vasopressin systems in genetic syndromes and neurodevelopmental disorders (2014) · cites this paper as Berry-Kravis et al., 2002
The behavioral and cognitive deficits of Fmr1 KO mice are actually quite subtle and parallel Fragile X syndrome patients.
“By most accounts Fmr1 KO mice appear to have relatively normal behavior, but research has shown that the behavioral and cognitive deficits of the KO are actually quite subtle and parallel FXS patients (Berry-Kravis et al., 2002; D’Hooge et al., 1997; Paradee et al., 1999; Peier et al., 2000).”
From Oxytocin and vasopressin systems in genetic syndromes and neurodevelopmental disorders (2014) · cites this paper as Berry-Kravis et al., 2002
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Noninvasive Test for Fragile X Syndrome, Using Hair Root Analysis
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Biology of the fragile X mental retardation protein, an RNA-binding protein
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A converging‐methods approach to fragile X syndrome
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Self-citationFragile X premutations and (TA)n estrogen receptor polymorphism in women with ovarian dysfunction
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Hagerman, R. J., Berry-Kravis, E., Hazlett, H. C., Bailey, D. B., Moine, H., Kooy, R. F., Tassone, F., Gantois, I., Sonenberg, N., Mandel, J. L., et al. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.65 · Cited by 838 · see citing works
Self-citationOpen-label add-on treatment trial of minocycline in fragile X syndrome.
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Self-citationOpen-Label Treatment Trial of Lithium to Target the Underlying Defect in Fragile X Syndrome
Berry-Kravis, E., Sumis, A., Hervey, C., Nelson, M., Porges, S. W., Weng, N., Weiler, I. J., & Greenough, W. T. (2008) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/dbp.0b013e31817dc447 · Cited by 215 · see citing works
Self-citationExperience effects on brain development: possible contributions to psychopathology
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Self-citationBehavioral phenotypes of genetic mouse models of autism
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Seizures in Fragile X Syndrome: Characteristics and Comorbid Diagnoses
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Self-citationPsychopharmacology in fragile X syndrome—Present and future
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Self-citationTherapeutic Strategies in Fragile X Syndrome: Dysregulated mGluR Signaling and Beyond
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Self-citationOxytocin and vasopressin systems in genetic syndromes and neurodevelopmental disorders
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Early‐phase ERK activation as a biomarker for metabolic status in fragile X syndrome
Weng, N., Weiler, I. J., Sumis, A. M., Berry‐Kravis, E., & Greenough, W. T. (2008) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30765 · Cited by 72 · see citing works
Self-citationModulation of the GABAergic pathway for the treatment of fragile X syndrome
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Fragile X syndrome and fragile X-associated tremor ataxia syndrome
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Self-citationPublic Health Literature Review of Fragile X Syndrome
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Cholesterol levels in Fragile X syndrome
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Self-citationClinic-Based Retrospective Analysis of Psychopharmacology for Behavior in Fragile X Syndrome
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Self-citationCharacterization of Potential Outcome Measures for Future Clinical Trials in Fragile X Syndrome
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Self-citationCaregiver Preferences for the Treatment of Males with Fragile X Syndrome
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Targeted treatments in fragile X syndrome
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Risperidone Treatment for Irritability in Fragile X Syndrome
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Molecular mechanisms for targeted treatments in fragile X syndrome
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Self-citationMotor stereotypies in fragile X syndrome
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Investigating Therapeutic Strategies for Fragile X Syndrome in Mice
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Self-citationDysregulated ERK signal pathway and immune profiles in Fragile X Syndrome
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Oxytocin and Vasopressin in Autism and Genetic Syndromes
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- Authors
- Berry-Kravis, E., Grossman, A. W., Crnic, L. S., & Greenough, W. T.
- Affiliations
- University of Illinois Urbana-Champaign (US)
- University of Colorado Anschutz (US)
- ORCID
- Grossman, Aaron W.
- Venue
- Current Paediatrics
- Publisher
- Elsevier BV
- Published
- 2002-08
- Volume
- 12
- Issue
- 4
- Pages
- 316-324
- ISSN
- 0957-5839 (ISSN-L)
- OpenAlex
- W2079802852
- Cited by
- 29
- References
- 23
- Citations by year
- 2023: 1 · 2020: 1 · 2018: 3 · 2017: 2 · 2016: 2 · 2015: 4 · 2014: 4 · 2012: 3
- FWCI
- 0.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Paediatrics (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Down syndrome and intellectual disability research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genomics and Rare Diseases
- Keywords
- fragile X syndrome, FMRP, intellectual disability, hyperactivity, anxiety, mitral valve prolapse, gastroesophageal reflux, otitis media, genetic counseling, behavior management
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