Glycaemic Control is Correlated with Well-Being Index (WHO-5) in Subjects with Type 2 Diabetes
Abstract
UNLABELLED: The aim of this study was to examine the potential correlation of WHO-5 well-being index with glycaemic control and chronic complications in subjects with type 2 diabetes. The study included 156 subjects (73 men, mean age 64.05+/-9.11 years, mean diabetes duration 12.22+/-5.61 years). Well-being was assessed by the WHO-5 score via a validated questionnaire comprising 5 questions (Q1-Q5). HbA (1c) showed a significant negative correlation with overall WHO-5 score (r (s)=-0.248, p=0.002) and individual Q1-Q4 scores (r (s)=-0.262, p=0.001; r (s)=-0.248, p=0.002; r (s)=-0.207, p=0.009 and r (s)=-0.169, p=0.035 respectively). Subjects with adequate glycaemic control (HbA (1c) < 7%, n=67) had a significantly higher WHO-5 score in comparison to those with inadequate glycaemic control (HbA (1c) >or= 7%, n=89) (mean+/-SD: 19.69+/-5.47 vs. mean+/-SD: 17.11+/-6.38, p=0.011). Finally, WHO-5 score was significantly (p=0.013) lower in subjects with neuropathic pain than in those without neuropathic pain. CONCLUSIONS: In type 2 diabetic subjects, glycaemic control shows a significant correlation with well-being, while neuropathic pain is associated with lower well-being score.
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In type 2 diabetes, positive psychological states are prospectively associated with lower HbA1c, fewer diabetes complications, and lower rates of cardiac events/mortality.
“In T2D, positive psychological states (e.g., positive affect, well-being) are prospectively associated with lower HbA1c, fewer diabetes complications, and lower rates of cardiac events/mortality [26–28]”
From Positive Psychological Interventions for Patients with Type 2 Diabetes: Rationale, Theoretical Model, and Intervention Development (2015) · cites this paper as [27]
Among people with diabetes, positive psychological attributes like optimism and positive affect correlate with better medical results, such as improved glucose control and reduced mortality.
“In patients with diabetes, psychological well-being constructs (e.g., optimism, positive affect) have been associated with superior medical outcomes, including better glucose control and lower mortality rates.”
From Well-being interventions for individuals with diabetes: A systematic review (2019) · cites this paper as [18]
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- Authors
- Papanas, N., Tsapas, A., Papatheodorou, K., Papazoglou, D., Bekiari, E., Sariganni, M., Paletas, K., & Maltezos, E.
- Affiliations
- Democritus University of Thrace (GR)
- Aristotle University of Thessaloniki (GR)
- Venue
- Experimental and Clinical Endocrinology & Diabetes
- Publisher
- Georg Thieme Verlag KG
- Published
- 2010-02-05
- Volume
- 118
- Issue
- 06
- Pages
- 364-367
- ISSN
- 0947-7349 (ISSN-L)
- 1439-3646
- OpenAlex
- W1992002699
- Cited by
- 40
- References
- 0
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 4 · 2023: 9 · 2021: 3 · 2020: 1 · 2019: 1 · 2018: 3 · 2017: 2 · 2016: 4 · 2015: 4 · 2013: 1 · 2012: 4
- FWCI
- 1.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Experimental and Clinical Endocrinology & Diabetes (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- type 2 diabetes, glycemic control, well-being, WHO-5, HbA1c, neuropathic pain, chronic complications, psychological well-being
- MeSH terms
- Aged, Attitude to Health, Blood Glucose, Diabetes Mellitus, Type 2, Diabetic Neuropathies, Female, Glycated Hemoglobin, Humans, Male, Middle Aged, Surveys and Questionnaires
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