Distress and Type 2 Diabetes Self-Care: Putting the Pieces Together
Open accessAbstract
Background: Conflicting research emphasizes depression, diabetes distress, or well-being in relation to diabetes self-care and risk for poor health outcomes. Purpose: The purpose of this study was to test whether a latent variable for general psychological distress derived from shared variance of depression symptoms, diabetes distress, and well-being predicts a latent variable of diabetes self-care and to examine evidence for unique effects once shared effects are adjusted for. Methods: Adults with suboptimally controlled diabetes were recruited from the South Bronx, NY, for a telephonic diabetes self-management support trial. Baseline diabetes self-care, medication adherence, depression symptoms, diabetes distress, and well-being were measured by validated self-report. Structural equation modeling specified a latent variable for general psychological distress derived from shared variance of depression symptoms, diabetes distress, and well-being. Diabetes self-care was a latent variable indicated by diet, glucose self-monitoring, and medication adherence. Results: Participants (N = 627, 65% female) were predominantly ethnic minority (70% Hispanic; 45% Black) and 77% reported household income <$20K/year. Mean (standard deviation) age = 56 (12) years; A1c = 9.1% (1.9%); body mass index = 32 (8) kg/m2. The latent variable for psychological distress was a robust predictor of poorer diabetes self-care (coefficient = −0.59 [confidence interval = −0.71, −0.46], p < .001) with good model fit. Unique paths from depression symptoms, diabetes distress, and well-being (all ps > .99) to self-care were not observed. Conclusions: In this population of disadvantaged adults with suboptimally controlled diabetes, general psychological distress was strongly associated with poorer diabetes self-care and fully accounted for the effects of depression, diabetes distress, and positive well-being. This suggests that general distress may underlie previously reported associations between these constructs and diabetes self-care.
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High levels of diabetes distress are known to negatively affect self-care behaviors, medication adherence, and glycemic control.
“This finding is clinically important, as high levels of diabetes distress are known to negatively affect self-care behaviors, medication adherence, and glycemic control [40-42].”
From Evaluation of the Impact of Mobile Health App Vitadio in Patients With Type 2 Diabetes: Randomized Controlled Trial (2025) · cites this paper as [41]
The Introduction (page unavailable) reports research associating diabetes-related distress with problematic self-care and glycemic control, and the Abstract identifies medication adherence as part of the self-care measure. But the paper calls the literature inconclusive and finds that diabetes distress has no independent association with self-care after accounting for general psychological distress. These associations do not establish that high diabetes distress itself negatively affects all three outcomes. (LLM, conf=0.86)
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Cites
Hu, L., & Bentler, P. M. (1999) · Structural Equation Modeling A Multidisciplinary Journal · doi:10.1080/10705519909540118 · Cited by 108,788 · see citing works
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267 · see citing works
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139 · see citing works
Testing Structural Equation Models.
Mueller, C. W., Bollen, K. A., & Long, J. S. (1994) · Contemporary Sociology A Journal of Reviews · doi:10.2307/2074955 · Cited by 14,211 · see citing works
Depression and quality of life in older persons: A review
Sivertsen, H., Bjørkløf, G. H., Engedal, K., Selbæk, G., & Helvik, A.-S. (2015) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000437299 · Cited by 14,152 · see citing works
Structural model evaluation and modification: An interval estimation approach
Steiger, J. H. (1990) · Multivariate Behavioral Research · doi:10.1207/s15327906mbr2502_4 · Cited by 7,408 · see citing works
Concurrent and Predictive Validity of a Self-reported Measure of Medication Adherence
Morisky, D. E., Green, L. W., & Levine, D. M. (1986) · Medical Care · doi:10.1097/00005650-198601000-00007 · Cited by 5,304 · see citing works
The PHQ-8 as a measure of current depression in the general population
Kroenke, K., Strine, T. W., Spitzer, R. L., Williams, J. B. W., Berry, J. T., & Mokdad, A. H. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.06.026 · Cited by 5,121 · see citing works
DiMatteo, M. R., Lepper, H. S., & Croghan, T. W. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.14.2101 · Cited by 4,177 · see citing works
The Prevalence of Comorbid Depression in Adults With Diabetes
Anderson, R. J., Freedland, K. E., Clouse, R. E., & Lustman, P. J. (2001) · Diabetes Care · doi:10.2337/diacare.24.6.1069 · Cited by 3,926 · see citing works
Psychological Stress and Disease
Cohen, S., Janicki-Deverts, D., & Miller, G. E. (2007) · JAMA · doi:10.1001/jama.298.14.1685 · Cited by 3,168 · see citing works
The summary of diabetes self-care activities measure: results from 7 studies and a revised scale.
Toobert, D. J., Hampson, S. E., & Glasgow, R. E. (2000) · Diabetes Care · doi:10.2337/diacare.23.7.943 · Cited by 2,561 · see citing works
Garnefski, N., Kraaij, V., Schroevers, M. J., & Somsen, G. A. (2008) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-008-9136-5 · Cited by 2,487 · see citing works
Selye, H. (1974) · Annals of Internal Medicine · doi:10.7326/0003-4819-81-5-716_1 · Cited by 2,221 · see citing works
Stress and Health: Major Findings and Policy Implications
Thoits, P. A. (2010) · Journal of Health and Social Behavior · doi:10.1177/0022146510383499 · Cited by 1,967 · see citing works
Depression and poor glycemic control: a meta-analytic review of the literature.
Lustman, P. J., Anderson, R. J., Freedland, K. E., de Groot, M., Carney, R. M., & Clouse, R. E. (2000) · Diabetes Care · doi:10.2337/diacare.23.7.934 · Cited by 1,854 · see citing works
Association of depression and diabetes complications: a meta-analysis
de Groot, M., Anderson, R., Freedland, K. E., Clouse, R. E., & Lustman, P. J. (2001) · Psychosomatic Medicine · doi:10.1097/00006842-200107000-00015 · Cited by 1,799 · see citing works
Chida, Y., & Steptoe, A. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31818105ba · Cited by 1,592 · see citing works
Assessing Psychosocial Distress in Diabetes
Polonsky, W. H., Fisher, L., Earles, J., Dudl, R. J., Lees, J., Mullan, J., & Jackson, R. A. (2005) · Diabetes Care · doi:10.2337/diacare.28.3.626 · Cited by 1,575 · see citing works
Depression as a risk factor for mortality in patients with coronary heart disease: a meta-analysis
Barth, J., Schumacher, M., & Herrmann-Lingen, C. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000146332.53619.b2 · Cited by 1,358 · see citing works
Live Events, Stress, and Illness
Rabkin, J. G., & Struening, E. L. (1976) · Science · doi:10.1126/science.790570 · Cited by 1,314 · see citing works
Ali, S., Stone, M. A., Peters, J., Davies, M. J., & Khunti, K. K. (2006) · Diabetic Medicine · doi:10.1111/j.1464-5491.2006.01943.x · Cited by 1,281 · see citing works
Strength and vulnerability integration: A model of emotional well-being across adulthood.
Charles, S. T. (2010) · Psychological Bulletin · doi:10.1037/a0021232 · Cited by 1,213 · see citing works
Young-Hyman, D., de Groot, M., Hill-Briggs, F., Gonzalez, J. S., Hood, K., & Peyrot, M. (2016) · Diabetes Care · doi:10.2337/dc16-2053 · Cited by 1,072 · see citing works
Self-citationDepression and Diabetes Treatment Nonadherence: A Meta-Analysis
Gonzalez, J. S., Peyrot, M., McCarl, L. A., Collins, E. M., Serpa, L., Mimiaga, M. J., & Safren, S. A. (2008) · Diabetes Care · doi:10.2337/dc08-1341 · Cited by 1,060 · see citing works
Self-citationStructural Equation Modeling: Strengths, Limitations, and Misconceptions
Tomarken, A. J., & Waller, N. G. (2004) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.1.102803.144239 · Cited by 892 · see citing works
Suls, J., & Bunde, J. (2005) · Psychological Bulletin · doi:10.1037/0033-2909.131.2.260 · Cited by 878 · see citing works
Distress Management, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology
Riba, M. B., Donovan, K. A., Andersen, B., Braun, I., Breitbart, W. S., Brewer, B. W., Buchmann, L. O., Clark, M. M., Collins, M., Corbett, C., et al. (2019) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2019.0048 · Cited by 871 · see citing works
Fisher, L., Mullan, J. T., Arean, P., Glasgow, R. E., Hessler, D., & Masharani, U. (2010) · Diabetes Care · doi:10.2337/dc09-1238 · Cited by 681 · see citing works
Handbook of Behavioral Medicine
Malec, J. F. (1985) · Psychosomatics · doi:10.1016/s0033-3182(85)72818-6 · Cited by 654 · see citing works
When Is Diabetes Distress Clinically Meaningful?
Fisher, L., Hessler, D. M., Polonsky, W. H., & Mullan, J. (2012) · Diabetes Care · doi:10.2337/dc11-1572 · Cited by 648 · see citing works
Depression, Self-Care, and Medication Adherence in Type 2 Diabetes
Gonzalez, J. S., Safren, S. A., Cagliero, E., Wexler, D. J., Delahanty, L., Wittenberg, E., Blais, M. A., Meigs, J. B., & Grant, R. W. (2007) · Diabetes Care · doi:10.2337/dc07-0158 · Cited by 579 · see citing works
Self-citationFisher, L., Gonzalez, J. S., & Polonsky, W. H. (2014) · Diabetic Medicine · doi:10.1111/dme.12428 · Cited by 470 · see citing works
Self-citationClinical Depression Versus Distress Among Patients With Type 2 Diabetes
Fisher, L., Skaff, M. M., Mullan, J. T., Arean, P., Mohr, D., Masharani, U., Glasgow, R., & Laurencin, G. (2007) · Diabetes Care · doi:10.2337/dc06-1614 · Cited by 466 · see citing works
Simms, L. J., Zelazny, K., Williams, T. F., & Bernstein, L. A. (2019) · Psychological Assessment · doi:10.1037/pas0000648 · Cited by 455 · see citing works
Self-reported distress: Analog or Ersatz depression?
Coyne, J. C. (1994) · Psychological Bulletin · doi:10.1037/0033-2909.116.1.29 · Cited by 434 · see citing works
Influence of race, ethnicity and social determinants of health on diabetes outcomes.
Walker, R. J., Strom Williams, J., & Egede, L. E. (2016) · The American Journal of the Medical Sciences · doi:10.1016/j.amjms.2016.01.008 · Cited by 431 · see citing works
A Review of Diabetes Treatment Adherence and the Association with Clinical and Economic Outcomes
Asche, C., LaFleur, J., & Conner, C. (2011) · Clinical Therapeutics · doi:10.1016/j.clinthera.2011.01.019 · Cited by 420 · see citing works
Validity of the five-item WHO Well-Being Index (WHO-5) in an elderly population
Heun, R., Bonsignore, M., Barkow, K., & Jessen, F. (2001) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf03035123 · Cited by 381 · see citing works
Urban neighborhood poverty and the incidence of depression in a population-based cohort study.
Galea, S., Ahern, J., Nandi, A., Tracy, M., Beard, J., & Vlahov, D. (2007) · Annals of Epidemiology · doi:10.1016/j.annepidem.2006.07.008 · Cited by 303 · see citing works
Depression in diabetes: have we been missing something important?
Gonzalez, J. S., Fisher, L., & Polonsky, W. H. (2011) · Diabetes Care · doi:10.2337/dc10-1970 · Cited by 302 · see citing works
Self-citationGonzalez, J. S., Penedo, F. J., Antoni, M. H., Durán, R. E., McPherson-Baker, S., Ironson, G. H., Fernandez, M. I., Klimas, N. G., FLETCHER, M. A., & Schneiderman, N. (2004) · Health Psychology · doi:10.1037/0278-6133.23.4.413 · Cited by 299 · see citing works
Self-citationProspective Associations Between Emotional Distress and Poor Outcomes in Type 2 Diabetes
Aikens, J. E. (2012) · Diabetes Care · doi:10.2337/dc12-0181 · Cited by 279 · see citing works
Symptoms and Well-Being in Relation to Glycemic Control in Type II Diabetes
Van der Does, F. E. E., De Neeling, J. N. D., Snoek, F. J., Kostense, P. J., Grootenhuis, P. A., Bouter, L. M., & Heine, R. J. (1996) · Diabetes Care · doi:10.2337/diacare.19.3.204 · Cited by 262 · see citing works
The Impact of Treatment Noncompliance on Mortality in People With Type 2 Diabetes
Currie, C. J., Peyrot, M. F., Morgan, C. L., Poole, C., Jenkins‐Jones, S., Rubin, R. R., Burton, C. M., & Evans, M. (2012) · Diabetes Care · doi:10.2337/dc11-1277 · Cited by 252 · see citing works
A Review of Treating Depression in Diabetes: Emerging Findings
Markowitz, S. M., Gonzalez, J. S., Wilkinson, J. L., & Safren, S. A. (2011) · Psychosomatics · doi:10.1016/j.psym.2010.11.007 · Cited by 230 · see citing works
Self-citationPositive affect uniquely predicts lower risk of mortality in people with diabetes.
Moskowitz, J. T., Epel, E. S., & Acree, M. (2008) · Health Psychology · doi:10.1037/0278-6133.27.1.s73 · Cited by 191 · see citing works
Effects of Enhanced Depression Treatment on Diabetes Self-Care
Lin, E. (2006) · The Annals of Family Medicine · doi:10.1370/afm.423 · Cited by 157 · see citing works
Stress and A1c Among People with Diabetes Across the Lifespan
Hilliard, M. E., Yi‐Frazier, J. P., Hessler, D., Butler, A. M., Anderson, B. J., & Jaser, S. S. (2016) · Current Diabetes Reports · doi:10.1007/s11892-016-0761-3 · Cited by 143 · see citing works
Gonzalez, J. S., Delahanty, L. M., Safren, S. A., Meigs, J. B., & Grant, R. W. (2008) · Diabetologia · doi:10.1007/s00125-008-1113-x · Cited by 117 · see citing works
Self-citationBjørner, J. B., Rose, M., Gandek, B., Stone, A. A., Junghaenel, D. U., & Ware, J. E. (2013) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2013.07.016 · Cited by 116 · see citing works
Gonzalez, J. S., Kane, N. S., Binko, D. H., Shapira, A., & Hoogendoorn, C. J. (2016) · Diabetes Care · doi:10.2337/dc16-1657 · Cited by 80 · see citing works
Self-citationMeasurement of Hostility, Anger, and Depression in Depressed and Nondepressed Subjects
Moreno, J. K., Fuhriman, A. J., & Selby, M. J. P. (1993) · Journal of Personality Assessment · doi:10.1207/s15327752jpa6103_7 · Cited by 78 · see citing works
Positive Emotional Health and Diabetes Care: Concepts, Measurement, and Clinical Implications
Robertson, S. M., Stanley, M. A., Cully, J. A., & Naik, A. D. (2012) · Psychosomatics · doi:10.1016/j.psym.2011.09.008 · Cited by 69 · see citing works
Tsenkova, V. K., Love, G. D., Singer, B. H., & Ryff, C. D. (2007) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318157466f · Cited by 63 · see citing works
Tracking Diabetes: New York City's A1C Registry
Chamany, S., Silver, L. D., Bassett, M. T., Driver, C. R., Berger, D. K., Neuhaus, C. E., Kumar, N., & Frieden, T. R. (2009) · Milbank Quarterly · doi:10.1111/j.1468-0009.2009.00568.x · Cited by 62 · see citing works
The well-being and treatment satisfaction of diabetic patients in primary care
Saatçı, E., Tahmiscioglu, G., Bozdemir, N., Akpınar, E., Özcan, S., & Kurdak, H. (2010) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-8-67 · Cited by 55 · see citing works
Glycaemic Control is Correlated with Well-Being Index (WHO-5) in Subjects with Type 2 Diabetes
Papanas, N., Tsapas, A., Papatheodorou, K., Papazoglou, D., Bekiari, E., Sariganni, M., Paletas, K., & Maltezos, E. (2010) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0029-1243623 · Cited by 40 · cited 1× · see citing works
“Additionally, positive psychological states have been associated with better glycemic control among individuals with and without diabetes [26, 32, 33].”
BackgroundShared Dysregulation of Homeostatic Brain-Body Pathways in Depression and Type 2 Diabetes
Hoogendoorn, C. J., Delgado, J. F. R., & Gonzalez, J. S. (2017) · Current Diabetes Reports · doi:10.1007/s11892-017-0923-y · Cited by 38 · see citing works
Self-citationNicolucci, A., Rossi, M. C., Pellegrini, F., Lucisano, G., Pintaudi, B., Gentile, S., Marra, G., Skovlund, S. E., & Vespasiani, G. (2014) · SpringerPlus · doi:10.1186/2193-1801-3-83 · Cited by 35 · see citing works
Prinz, N., Ebner, S., Grünerbel, A., Henkelüdecke, U., Hermanns, N., Hummel, M., Schäfer, C., Wagner, C., Weiland, J., Welp, R., et al. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.08.077 · Cited by 26 · see citing works
Miles, S. R., Khambaty, T., Petersen, N. J., Naik, A. D., & Cully, J. A. (2018) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-017-9527-6 · Cited by 19 · see citing works
van Vugt, M., de Wit, M., Bader, S., & Snoek, F. J. (2015) · Primary care diabetes · doi:10.1016/j.pcd.2015.06.008 · Cited by 13 · see citing works
Diabetes stress and health: Is aging a strength or a vulnerability?
Helgeson, V. S., Vleet, M. V., & Zajdel, M. (2019) · Journal of Behavioral Medicine · doi:10.1007/s10865-019-00106-4 · Cited by 13 · see citing works
Baseline Characteristics and Latino Versus Non-Latino Contrasts Among Bronx A1C Study Participants
Walker, E. A., Silver, L. D., Chamany, S., Schechter, C. B., Gonzalez, J. S., Carrasco, J., Powell, D., Berger, D. K., & Basch, C. E. (2014) · Western Journal of Nursing Research · doi:10.1177/0193945913517947 · Cited by 7 · see citing works
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Bretschneider, M. P., Kolasińska, A. B., Šomvárska, L., Klásek, J., Mareš, J., & Schwarz, P. E. (2025) · Journal of Medical Internet Research · doi:10.2196/68648 · Cited by 15 · see citing works
- Authors
- Hoogendoorn, C. J., Schechter, C. B., Llabre, M. M., Walker, E. A., & Gonzalez, J. S.
- Affiliations
- Yeshiva University (US)
- Albert Einstein College of Medicine (US)
- University of Miami (US)
- Corresponding author
- Hoogendoorn, Claire J
- Venue
- Annals of Behavioral Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2020-09-11
- Volume
- 55
- Issue
- 10
- Pages
- 938-948
- ISSN
- 0742-5554 (ISSN-L)
- 0883-6612
- 1532-4796
- PMC
- PMC8489306
- OpenAlex
- W3086578826
- Cited by
- 28
- References
- 65
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 8 · 2023: 3 · 2022: 3 · 2021: 4
- FWCI
- 1.88
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- Annals of Behavioral Medicine (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (R18 DK078077)
- Einstein-Mount Sinai Diabetes Research Center,
- Albert Einstein College of Medicine (P30 DK020541)
- New York Regional Center for Diabetes Translation Research (P30 DK111022)
- David and Jane Willner Bloomgarden Family Fellowship Fund (R01 DK104845, R18 DK098742, R01 DK121298, R01 DK121896)
- National Institutes of Health
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Keywords
- diabetes self-care, psychological distress, diabetes distress, depression, well-being, medication adherence, self-monitoring of blood glucose, diet, Hispanic adults, ethnic minority health, diabetes self-management support, shared variance
- MeSH terms
- Ethnic and Racial Minorities, Adult, Depression, Diabetes Mellitus, Type 2, Ethnicity, Female, Humans, Male, Middle Aged, Minority Groups, Self Care, Stress, Psychological
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