The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Medication Use in the Neonatal Intensive Care Unit
Open accessAbstract
OBJECTIVE: The aim of the article is to provide an update on medication use in infants admitted to the neonatal intensive care unit (NICU) in the United States and examine how use has changed over time. STUDY DESIGN: We performed a retrospective review (2005-2010) of a large prospectively collected administrative database. RESULT: Medications most commonly administered during the study period were ampicillin, gentamicin, caffeine citrate, vancomycin, beractant, furosemide, fentanyl, dopamine, midazolam, and calfactant (56-681 exposures per 1,000 infants). Those with the greatest relative increase in use included azithromycin, sildenafil, and milrinone. Medications with the greatest relative decrease in use included theophylline, metoclopramide, and doxapram. CONCLUSION: Medication use in the NICU has changed substantially over time, and only 35% of the most commonly prescribed medications are Food and Drug Administration -approved in infants.
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Benjamin, D. K., Stoll, B. J., Fanaroff, A. A., McDonald, S. A., Oh, W., Higgins, R. D., Duara, S., Poole, K., Laptook, A., Goldberg, R., et al. (2006) · Pediatrics · doi:10.1542/peds.2004-2292 · Cited by 667
Self-citationA Comparison of Ibuprofen and Indomethacin for Closure of Patent Ductus Arteriosus
Van Overmeire, B., Smets, K., Lecoutere, D., Van de Broek, H., Weyler, J., De Groote, K., & Langhendries, J.-P. (2000) · New England Journal of Medicine · doi:10.1056/nejm200009073431001 · Cited by 447
Guillet, R., Stoll, B. J., Cotten, C. M., Gantz, M., McDonald, S., Poole, W. K., Phelps, D. L., & for members of the National Institute of Child Health and Human Development Neonatal Research Network (2006) · Pediatrics · doi:10.1542/peds.2005-1543 · Cited by 429
Reported Medication Use in the Neonatal Intensive Care Unit: Data From a Large National Data Set
Clark, R. H., Bloom, B. T., Spitzer, A. R., & Gerstmann, D. R. (2006) · Pediatrics · doi:10.1542/peds.2005-1707 · Cited by 416
Self-citationBarst, R. J., Ivy, D. D., Gaitan, G., Szatmari, A., Rudzinski, A., Garcia, A. E., Sastry, B. K. S., Pulido, T., Layton, G. R., Serdarevic-Pehar, M., et al. (2012) · Circulation · doi:10.1161/circulationaha.110.016667 · Cited by 372
A Multicenter, Randomized Trial of Prophylactic Fluconazole in Preterm Neonates
Manzoni, P., Stolfi, I., Pugni, L., Decembrino, L., Magnani, C., Vetrano, G., Tridapalli, E., Corona, G., Giovannozzi, C., Farina, D., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa065733 · Cited by 356
A literature review on off-label drug use in children
Pandolfini, C., & Bonati, M. (2005) · European Journal of Pediatrics · doi:10.1007/s00431-005-1698-8 · Cited by 346
Adverse drug reactions and off-label drug use in paediatric outpatients
Horen, B., Montastruc, J.-L., & Lapeyre-Mestre, M. (2002) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.2002.t01-3-01689.x · Cited by 294
Cuzzolin, L., Atzei, A., & Fanos, V. (2006) · Expert Opinion on Drug Safety · doi:10.1517/14740338.5.5.703 · Cited by 252
Population Pharmacokinetics of Fluconazole in Young Infants
Wade, K. C., Wu, D., Kaufman, D. A., Ward, R. M., Benjamin, D. K., Sullivan, J. E., Ramey, N., Jayaraman, B., Hoppu, K., Adamson, P. C., et al. (2008) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00569-08 · Cited by 177
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Cited by
Esaiassen, E., Hjerde, E., Cavanagh, J. P., Pedersen, T., Andresen, J. H., Rettedal, S. I., Støen, R., Nakstad, B., Willassen, N. P., & Klingenberg, C. (2018) · Frontiers in Pediatrics · doi:10.3389/fped.2018.00347 · Cited by 102
Antibiotic administration and the development of obesity in children
Principi, N., & Esposito, S. (2016) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2015.12.017 · Cited by 70
Guitor, A. K., Yousuf, E. I., Raphenya, A. R., Hutton, E. K., Morrison, K. M., McArthur, A. G., Wright, G. D., & Stearns, J. C. (2022) · Microbiome · doi:10.1186/s40168-022-01327-7 · Cited by 44
Metadata
- Authors
- Hsieh, E., Hornik, C., Clark, R., Laughon, M., Benjamin, D., Smith, P., & on Behalf of the Best Pharmaceuticals for Children Act—Pediatric Trials Network
- Venue
- American Journal of Perinatology
- Publisher
- Georg Thieme Verlag KG
- Published
- 2013-12-17
- Volume
- 31
- Issue
- 09
- Pages
- 811-822
- ISSN
- 0735-1631 (ISSN-L)
- 1098-8785
- OpenAlex
- W2033829367
- Cited by
- 318
- References
- 16
- FWCI
- 12.30
- Type
- journal article
- Language
- en
- Open access
- green
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- Hsieh, E., Hornik, C., Clark, R., Laughon, M., Benjamin, D., Smith, P., & on Behalf of the Best Pharmaceuticals for Children Act—Pediatric Trials Network. (2013). Medication Use in the Neonatal Intensive Care Unit. American Journal of Perinatology. https://doi.org/10.1055/s-0033-1361933
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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