Gestational Weight Gain and Pregnancy Outcomes among Nulliparous Women
Open accessAbstract
Objective To determine the association between total gestational weight gain and perinatal outcomes. Study Design Data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-To-Be (NuMoM2b) study were used. Total gestational weight gain was categorized as inadequate, adequate, or excessive based on the 2009 Institute of Medicine guidelines. Outcomes examined included hypertensive disorders of pregnancy, mode of delivery, shoulder dystocia, large for gestational age or small for-gestational age birth weight, and neonatal intensive care unit admission. Results Among 8,628 women, 1,666 (19.3%) had inadequate, 2,945 (34.1%) had adequate, and 4,017 (46.6%) had excessive gestational weight gain. Excessive gestational weight gain was associated with higher odds of hypertensive disorders (adjusted odds ratio [aOR] = 2.05, 95% confidence interval [CI]: 1.78–2.36) Cesarean delivery (aOR = 1.24, 95% CI: 1.09–1.41), and large for gestational age birth weight (aOR = 1.49, 95% CI: 1.23–1.80), but lower odds of small for gestational age birth weight (aOR = 0.59, 95% CI: 0.50–0.71). Conversely, inadequate gestational weight gain was associated with lower odds of hypertensive disorders (aOR = 0.75, 95% CI: 0.62–0.92), Cesarean delivery (aOR = 0.77, 95% CI: 0.65–0.92), and a large for gestational age birth weight (aOR = 0.72, 95% CI: 0.55–0.94), but higher odds of having a small for gestational age birth weight (aOR = 1.64, 95% CI: 1.37–1.96). Conclusion Both excessive and inadequate gestational weight gain are associated with adverse maternal and neonatal outcomes.
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- Authors
- Dude, A. M., Grobman, W., Haas, D., Mercer, B. M., Parry, S., Silver, R. M., Wapner, R., Wing, D., Saade, G., Reddy, U., Iams, J., & Kominiarek, M. A.
- Affiliations
- Northwestern University (US)
- Indiana University School of Medicine (US)
- MetroHealth Medical Center (US)
- University of Pennsylvania (US)
- University of Utah (US)
- Columbia University Irving Medical Center (US)
- University of California, Irvine (US)
- The University of Texas Medical Branch at Galveston (US)
- Yale University (US)
- The Ohio State University (US)
- Corresponding author
- Dude, Annie M.
- ORCID
- Venue
- American Journal of Perinatology
- Publisher
- Georg Thieme Verlag KG
- Published
- 2019-09-06
- Volume
- 38
- Issue
- 02
- Pages
- 182-190
- ISSN
- 0735-1631 (ISSN-L)
- 1098-8785
- PMC
- PMC7071163
- OpenAlex
- W2971716478
- Semantic Scholar
- 31569046ebce64e9348e26326e6f5d707cc4f394
- Cited by
- 39
- References
- 38
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 9 · 2023: 11 · 2022: 5 · 2021: 2 · 2020: 2
- FWCI
- 2.45
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Perinatology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Purdue University Indianapolis (Indiana University) (submittedVersion)
- IUScholarWorks (Indiana University) (submittedVersion)
- Funders
- University of Pennsylvania (U10 HD063046, U10 HD063020, U10 HD063047, U10 HD063072, U10 HD063036, U10 HD063053, U10 HD063037, U10HD063048)
- Northwestern University (U10 HD063053, U10 HD063020, U10 HD063046, U10 HD063048, U10 HD063072, U10 HD063036, U10 HD063047, U10 HD063037)
- University of Pittsburgh (U10 HD063020, U10 HD063046, U10 HD063072, U10 HD063048, U10 HD063041, U10 HD063037, U10 HD063047, U10 HD063053, U10 HD063036)
- Case Western Reserve University (U10 HD063036, U10 HD063072, U10 HD063046, U10 HD063053, U10 HD063020, U10 HD063037, U10 HD063047, U10 HD063048)
- RTI International (U10HD063036, U10 HD063072)
- Natera
- National Institutes of Health (UL1TR001108, UL1TR001414, UL1TR000153, UL1TR001863)
- University of California, Irvine (U10 HD063048, U10 HD063047, U10 HD063037, U10 HD063020, U10 HD063053, U10 HD063072, U10 HD063036, UL1 TR000153, U10 HD063046)
- National Institute of Child Health and Human Development
- National Center for Advancing Translational Sciences
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10HD063053, U10HD063046, U10HD063020, U10HD063072, HD063036, U10HD063048, U10HD063041, U10HD063047, U10HD063036, U10HD063037)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
- Keywords
- gestational weight gain, nulliparous women, hypertensive disorders of pregnancy, cesarean section, shoulder dystocia, large for gestational age, small for gestational age, neonatal intensive care admission, Institute of Medicine guidelines, perinatal outcomes
- MeSH terms
- Gestational Weight Gain, Adolescent, Adult, Birth Weight, Cesarean Section, Female, Gestational Age, Humans, Hypertension, Infant, Newborn, Infant, Small for Gestational Age, Parity, Pregnancy, Pregnancy Outcome, Prospective Studies, United States, Multivariate Analysis, Logistic Models, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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