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History of The Endocrine Effects of Licorice
Abstract
The history of licorice as an officinal plant dates back thousands of years, and licorice is still appreciated as a medicinal root. Many of its endocrine properties can be derived from observations of Authors of the ancient world, when hormones were not known. Inappropriate use of licorice can produce pseudoaldosteronism, by inactivating 11beta-hydroxysteroiod-dehydrogenase and by binding to mineralocorticoid receptors. Licorice possesses many other therapeutic properties as to potentiate the action of cortisol, to reduce testosterone synthesis, especially in women, to exert an estrogen-like activity and to reduce body fat mass. The chronological development of research on these effects is described.
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Cited by
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Pastorino, G., Cornara, L., Soares, S., Rodrigues, F., & Oliveira, M. B. P. P. (2018) · Phytotherapy Research · doi:10.1002/ptr.6178 · Cited by 804
Antiviral effects of Glycyrrhiza species
Fiore, C., Eisenhut, M., Krausse, R., Ragazzi, E., Pellati, D., Armanini, D., & Bielenberg, J. (2008) · Phytotherapy Research · doi:10.1002/ptr.2295 · Cited by 458
Self-citationAn Overview of the Evidence and Mechanisms of Herb–Drug Interactions
Fasinu, P. S., Bouic, P. J., & Rosenkranz, B. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00069 · Cited by 221
Anti-inflammatory efficacy of Licochalcone A: Correlation of clinical potency and in vitro effects
Kolbe, L., Immeyer, J., Batzer, J., Wensorra, U., Dieck, K. T., Mundt, C., Wolber, R., Stäb, F., Schönrock, U., Ceilley, R. I., et al. (2006) · Archives of Dermatological Research · doi:10.1007/s00403-006-0654-4 · Cited by 151
Apparent mineralocorticoid excess syndrome: an overview
Palermo, M., Quinkler, M., & Stewart, P. M. (2004) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302004000500015 · Cited by 92
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Metadata
- Authors
- Armanini, D., Fiore, C., Mattarello, M., Bielenberg, J., & Palermo, M.
- Venue
- Experimental and Clinical Endocrinology & Diabetes
- Publisher
- Georg Thieme Verlag KG
- Published
- 2002-10-09
- Volume
- 110
- Issue
- 06
- Pages
- 257-261
- ISSN
- 0947-7349 (ISSN-L)
- 1439-3646
- OpenAlex
- W1975756746
- Cited by
- 188
- References
- 0
- FWCI
- 3.38
- Type
- journal article
- Language
- en
- Open access
- closed
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- Armanini, D., Fiore, C., Mattarello, M., Bielenberg, J., & Palermo, M. (2002). History of The Endocrine Effects of Licorice. Experimental and Clinical Endocrinology & Diabetes. https://doi.org/10.1055/s-2002-34587
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