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Cited by 897

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

The Role of Inflammation and Infection in Preterm Birth

Open access
Romero, Roberto, Espinoza, Jimmy, Gonçalves, Luís, Kusanovic, Juan, Friel, Lara, Hassan, Sonia·2007·Seminars in Reproductive Medicine

Abstract

Inflammation has been implicated in the mechanisms responsible for preterm and term parturition, as well as fetal injury. Out of all of the suspected causes of preterm labor and delivery, infection and/or inflammation is the only pathological process for which both a firm causal link with preterm birth has been established and a molecular pathophysiology defined. Inflammation has also been implicated in the mechanism of spontaneous parturition at term. Most cases of histopathological inflammation and histological chorioamnionitis, both in preterm and term labor, are sub-clinical in nature. The isolation of bacteria in the amniotic fluid, known as microbial invasion of the amniotic cavity, is a pathological finding; the frequency of which is dependent upon the clinical presentation and gestational age. This article reviews the role of inflammation in preterm and term parturition.

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Metadata

Authors
Romero, R., Espinoza, J., Gonçalves, L., Kusanovic, J., Friel, L., & Hassan, S.
Venue
Seminars in Reproductive Medicine
Published
2007-01
Volume
25
Issue
1
Pages
021-039
ISSN
  • 1526-4564 (ISSN-L)
  • 1526-8004
OpenAlex
W2024179737
Cited by
897
References
10
FWCI
24.71
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The Role of Inflammation and Infection in Preterm Birth. https://app.cochat.ai/papers/10.1055/s-2006-956773
The paper
Romero, R., Espinoza, J., Gonçalves, L., Kusanovic, J., Friel, L., & Hassan, S. (2007). The Role of Inflammation and Infection in Preterm Birth. Seminars in Reproductive Medicine. https://doi.org/10.1055/s-2006-956773

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.