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Antioxidant and Radical Scavenging Effects of Aged Garlic Extract and its Constituents
Abstract
The antioxidant properties of three garlic preparations and organosulfur compounds in garlic have been determined. Aged garlic extract inhibited the emission of low level chemiluminescence and the early formation of thiobarbituric acid-reactive substances (TBA-RS) in liver microsomal fraction initiated by t-butyl hydroperoxide. However, the water extracts of raw and heat-treated garlic enhanced the emission of low level chemiluminescence. Among the variety of organosulfur compounds, S-allylcysteine (SAC) and S-allylmercaptocysteine (SAMC), the major organosulfur compounds found in aged garlic extract, showed radical scavenging activity in both chemiluminescence and 1,1-diphenyl-2-picrylhydrazyl (DPPH) assays, indicating that these compounds may play an important role in the antioxidative activity of aged garlic extract.
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Citations
Cited by
Intake of Garlic and Its Bioactive Components
Amagase, H., Petesch, B. L., Matsuura, H., Kasuga, S., & Itakura, Y. (2001) · The Journal of Nutrition · doi:10.1093/jn/131.3.955s · Cited by 1,049
Self-citationBiological properties of onions and garlic
CORZOMARTINEZ, M., CORZO, N., & VILLAMIEL, M. (2007) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2007.07.011 · Cited by 810
Antioxidant Health Effects of Aged Garlic Extract
Borek, C. (2001) · The Journal of Nutrition · doi:10.1093/jn/131.3.1010s · Cited by 688
Clarifying the real bioactive constituents of garlic
Amagase, H. (2006) · The Journal of Nutrition · doi:10.1093/jn/136.3.716s · Cited by 680
Garlic [Allium sativum]: A review of its potential use as an anti-cancer agent
Thomson, M., & Ali, M. (2003) · Current Cancer Drug Targets · doi:10.2174/1568009033333736 · Cited by 399
Metadata
- Authors
- Imai, J., Ide, N., Nagae, S., Moriguchi, T., Matsuura, H., & Itakura, Y.
- Venue
- Planta Medica
- Publisher
- Georg Thieme Verlag KG
- Published
- 1994-10
- Volume
- 60
- Issue
- 05
- Pages
- 417-420
- ISSN
- 0032-0943 (ISSN-L)
- 1439-0221
- OpenAlex
- W2058164136
- Cited by
- 442
- References
- 0
- FWCI
- 5.89
- Type
- journal article
- Language
- en
- Open access
- closed
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- Imai, J., Ide, N., Nagae, S., Moriguchi, T., Matsuura, H., & Itakura, Y. (1994). Antioxidant and Radical Scavenging Effects of Aged Garlic Extract and its Constituents. Planta Medica. https://doi.org/10.1055/s-2006-959522
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