Follow-up of Solitary Autonomous Thyroid Nodules Treated with 131I
Abstract
We studied the long-term effects of 131I therapy for solitary autonomous thyroid nodules on the size of the nodule and on thyroid function. Twenty-three patients with autonomous thyroid adenomas that had been treated with 131I from 4 to 16.5 years earlier (mean, 8.5) were examined, and their thyroid function was tested. In 12 patients (54 per cent), the nodules were still palpable, and in 2 they had increased in size. Eight patients (36 per cent) had become hypothyroid. The incidence of hypothyroidism was not related to nodule size or the level of thyroid function before therapy with 131I or to the total dose of 131I that had been given. We conclude that 131I therapy for autonomous thyroid adenoma often causes hypothyroidism and in many cases does not eradicate the offending nodule.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The prevalence of hypothyroidism after RAI for TA is progressive and hastened by the presence of antithyroid antibodies or a nonsuppressed TSH at the time of treatment.
“The prevalence of hypothyroidism after RAI is progressive and hastened by the presence of antithyroid antibodies or a nonsuppressed TSH at the time of treatment (257,259,260).”
From 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis (2016) · cites this paper as [260]
The nodule is rarely eradicated in patients with TA undergoing RAI therapy, which can lead to the need for continued surveillance.
“The nodule is rarely eradicated in patients with TA undergoing RAI therapy, which can lead to the need for continued surveillance (225,257,260).”
From 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis (2016) · cites this paper as [260]
Cites
Solitary autonomously functioning thyroid lesions
Hamburger, J. I. (1975) · The American Journal of Medicine · doi:10.1016/0002-9343(75)90630-0 · Cited by 113 · see citing works
THE STUDY AND TREATMENT OF 119 CASES OF CARCINOMA OF THE THYROID WITH RADIOACTIVE IODINE*†
DOBYNS, B. M., & Maloof, F. (1951) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-11-11-1323 · Cited by 92 · see citing works
Miller, J. M., & Hamburger, J. I. (1965) · Radiology · doi:10.1148/84.1.66 · Cited by 91 · see citing works
Horst, W., Rösler, H., Schneider, C. G., & Labhart, A. (1967) · PubMed · Cited by 79 · see citing works
The autonomous nodule of the thyroid: correlation of patient age, nodule size and functional status
Blum, M., SHENKMAN, L., & Hollander, C. S. (1975) · The American Journal of the Medical Sciences · doi:10.1097/00000441-197501000-00006 · Cited by 69 · see citing works
Radiation Dose in the Selection of 131I or Surgical Treatment for Toxic Thyroid Adenoma
Gorman, C. A., & ROBERTSON, J. S. (1978) · Annals of Internal Medicine · doi:10.7326/0003-4819-89-1-85 · Cited by 65 · see citing works
ON THE HYPERFUNCTIONING SOLITARY THYROID NODULE
Molnar, G. D., Wilber, R. D., Lee, R. E., Woolner, L. B., & KEATING, F. R. (1965) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(25)14212-2 · Cited by 58 · see citing works
THE CLINICAL AND PATHOLOGIC RELATIONSHIPS OF HYPERPLASTIC AND NONHYPERPLASTIC GOITER
Plummer, H. S. (1913) · JAMA · doi:10.1001/jama.1913.04350090018006 · Cited by 55 · see citing works
The Natural History of the Autonomous Hyperfunctioning Thyroid Nodule
Silverstein, G. E., BURKE, G., & COGAN, R. (1967) · Annals of Internal Medicine · doi:10.7326/0003-4819-67-3-539 · Cited by 52 · see citing works
Radioiodine in Diagnosis and Therapy of Hyperthyroidism
Skillern, P. G. (1962) · Archives of Internal Medicine · doi:10.1001/archinte.1962.03620240070011 · Cited by 43 · see citing works
Solitary toxic adenoma of the thyroid gland
Bransom, C. J., Talbot, C. H., Henry, L., & Elemenoglou, J. (1979) · British journal of surgery · doi:10.1002/bjs.1800660823 · Cited by 40 · see citing works
Long-term studies of solitary autonomous thyroid nodules.
McCormack, K. R., & Sheline, G. E. (1967) · PubMed · Cited by 29 · see citing works
Hamburger, J. I. (1981) · Springer eBooks · doi:10.1007/978-1-4612-5916-9_3 · Cited by 11 · see citing works
Ramsay, I., Richardson, P. J., Marsden, P. D., & McKERRON, C. G. (1972) · Postgraduate Medical Journal · doi:10.1136/pgmj.48.564.577 · Cited by 6 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Ross, D. S., Burch, H. B., Cooper, D. S., Greenlee, M. C., Laurberg, P., Maia, A. L., Rivkees, S. A., Samuels, M., Sosa, J. A., Stan, M. N., et al. (2016) · Thyroid® · doi:10.1089/thy.2016.0229 · Cited by 2,938 · see citing works
“The prevalence of hypothyroidism after RAI is progressive and hastened by the presence of antithyroid antibodies or a nonsuppressed TSH at the time of treatment (257,259,260).”
BackgroundBahn, R. S., Burch, H. B., Cooper, D. S., Garber, J. R., Greenlee, M. C., Klein, I., Laurberg, P., McDougall, I. R., Montori, V. M., Rivkees, S. A., et al. (2011) · Endocrine Practice · doi:10.4158/ep.17.3.456 · Cited by 1,098 · see citing works
The American Thyroid Association and American Association of Clinical Endocrinologists Taskforce on Hyperthyroidism and Other Causes of Thyrotoxicosis, Bahn, R. S., Burch, H. B., Cooper, D. S., Garber, J. R., Greenlee, M. C., Klein, I., Laurberg, P., McDougall, I. R., Montori, V. M., et al. (2011) · Thyroid · doi:10.1089/thy.2010.0417 · Cited by 898 · see citing works
Management of Simple Nodular Goiter: Current Status and Future Perspectives
Hegedűs, L. D., Bonnema, S. J., & Bennedbæk, F. N. (2003) · Endocrine Reviews · doi:10.1210/er.2002-0016 · Cited by 707 · see citing works
Iodide transport in the thyroid gland
Carrasco, N. (1993) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(93)90017-i · Cited by 365 · see citing works
The Management of Hyperthyroidism
Wood, A. J. J., & Franklyn, J. A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199406163302407 · Cited by 303 · see citing works
Radioiodine Therapy for Hyperthyroidism
Ross, D. S. (2011) · New England Journal of Medicine · doi:10.1056/nejmct1007101 · Cited by 282 · see citing works
Controversies in the management of cold, hot, and occult thyroid nodules
Giuffrida, D., & Gharib, H. (1995) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)80252-6 · Cited by 203 · see citing works
Solitary Thyroid Nodule: Diagnosis and Management
Mazzaferri, E. L., Santos, E. T. D. L., & Keyhani‐Rofagha, S. (1988) · Medical Clinics of North America · doi:10.1016/s0025-7125(16)30736-2 · Cited by 161 · see citing works
Nygaard, B., Hegedüs, L., Gerhard Nielsen, K., Ulriksen, P., & Hansen, J. M. (1999) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1999.00635.x · Cited by 148 · see citing works
Percutaneous Ethanol Injection Treatment in Benign Thyroid Lesions: Role and Efficacy
Guglielmi, R., Pacella, C. M., Bianchini, A., Bizzarri, G., Rinaldi, R., Graziano, F. M., Petrucci, L., Toscano, V., Palma, E., Poggi, M., et al. (2004) · Thyroid · doi:10.1089/105072504322880364 · Cited by 150 · see citing works
Hypothyroidism in the Elderly*
ROBUSCHI, G., Safran, M., Braverman, L. E., GNUDI, A., & Roti, E. (1987) · Endocrine Reviews · doi:10.1210/edrv-8-2-142 · Cited by 140 · see citing works
Lippi, F., Ferrari, G. C., Manetti, L., Rago, T., Santini, F., Monzani, F., Bellitti, P., Papini, E., Busnardo, B., Angelini, F., et al. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.9.8784080 · Cited by 136 · see citing works
TREATMENT OF GRAVES' DISEASE: THE ADVANTAGES OF SURGERY
Alsanea, O., & Clark, O. H. (2000) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70134-1 · Cited by 126 · see citing works
Radioiodine Therapy for Multinodular Toxic Goiter
Nygaard, B., Hegedüs, L., Ulriksen, P., Nielsen, K. G., & Hansen, J. M. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.12.1364 · Cited by 120 · see citing works
Spiezia, S., Vitale, G., Somma, C. D., Assanti, A. P., Ciccarelli, A., Lombardi, G., & Colao, A. (2003) · Thyroid · doi:10.1089/105072503322511346 · Cited by 116 · see citing works
Ceccarelli, C., Bencivelli, W., Vitti, P., Grasso, L., & Pinchera, A. (2005) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2005.02218.x · Cited by 109 · see citing works
Papini, E., Panunzi, C., Pacella, C. M., Bizzarri, G., Fabbrini, R., Petrucci, L., Pisicchio, G., & Nardi, F. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.76.2.8432784 · Cited by 92 · see citing works
The Autonomously Functioning Thyroid Nodule: Goetsch's Disease
Hamburger, J. I. (1987) · Endocrine Reviews · doi:10.1210/edrv-8-4-439 · Cited by 91 · see citing works
Ross, D. S., Ridgway, E. C., & DANIELS, G. H. (1984) · Annals of Internal Medicine · doi:10.7326/0003-4819-101-4-488 · Cited by 90 · see citing works
Scintigraphic Manifestations of Thyrotoxicosis
INTENZO, C. M., dePapp, A. E., Jabbour, S., Miller, J. L., Kim, S. M., & Capuzzi, D. M. (2003) · Radiographics · doi:10.1148/rg.234025716 · Cited by 84 · see citing works
Iodine‐131 treatment of hyperthyroidism: current issues
Farrar, J., & Toft, A. D. (1991) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1991.tb03523.x · Cited by 68 · see citing works
Tarantino, L., Francica, G., Sordelli, I., Sperlongano, P., Parmeggiani, D., Ripa, C., & Parmeggiani, U. (2008) · American Journal of Roentgenology · doi:10.2214/ajr.07.2668 · Cited by 67 · see citing works
Rosaí, J., & Tallini, G. (2011) · Elsevier eBooks · doi:10.1016/b978-0-323-06969-4.00015-5 · Cited by 66 · see citing works
Martino, E., Murtas, M. L., Loviselli, A., Piga, M., Petrini, L., Miccoli, P., & Pacini, F. (1992) · PubMed · Cited by 64 · see citing works
Monzanl, F., Golettl, O., Caracclo, N., Guerra, P. D., Ferdeghinl, M., Puccl, E., & Baschieri, L. (1992) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1992.tb02251.x · Cited by 62 · see citing works
Berglund, J., Christensen, S. B., Dymling, J. ‐., & Hallengren, B. (1991) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.1991.tb00371.x · Cited by 57 · see citing works
Zingrillo, M., Torlontano, M., Ghiggi, M. R., Frusciante, V., Varraso, A., Liuzzi, A., & Trischitta, V. (2000) · Thyroid · doi:10.1089/thy.2000.10.985 · Cited by 54 · see citing works
Vidal-Trecan, G. M., Stahl, J. E., & Eckman, M. H. (2004) · Thyroid · doi:10.1089/thy.2004.14.933 · Cited by 53 · see citing works
Thyroid cancer prevalence after radioiodine treatment of hyperthyroidism.
Angusti, T., Codegone, A., Pellerito, R. E., & Favero, A. (2000) · PubMed · Cited by 53 · see citing works
Treatment of autonomous thyroid nodules: value of percutaneous ethanol injection.
Lelio, A. D., Rivolta, M., Casati, M., & Capra, M. (1995) · American Journal of Roentgenology · doi:10.2214/ajr.164.1.7998541 · Cited by 45 · see citing works
Percutaneous intranodular ethanol injection: A new treatment for autonomous thyroid adenoma
PARACCHI, A., Ferrari, G. C., Livraghi, T., Reschini, E., Macchi, R. M., Bergonzi, M., & Raineri, P. (1992) · Journal of Endocrinological Investigation · doi:10.1007/bf03348753 · Cited by 44 · see citing works
Treatment of toxic solitary thyroid nodules: surgery versus radioactive iodine.
O’Brien, T., Gharib, H., Suman, V. J., & van Heerden, J. A. (1992) · PubMed · Cited by 43 · see citing works
Current Management of the Patient with Autonomously Functioning Nodular Goiter
Thomas, C. G., & Croom, R. D. (1987) · Surgical Clinics of North America · doi:10.1016/s0039-6109(16)44186-1 · Cited by 43 · see citing works
Acute and Subacute, and Riedel’s Thyroiditis
Shrestha, R. T., & Hennessey, J. V. (2015) · Europe PMC (PubMed Central) · Cited by 37 · see citing works
Percutaneous injection of ethanol to treat autonomous thyroid nodules.
Mazzeo, S., Toni, M., Gaudio, C. D., Caramella, D., Pinto, F., Lencioni, R. A., Sanguinetti, F., & Bartolozzi, C. (1993) · American Journal of Roentgenology · doi:10.2214/ajr.161.4.8372778 · Cited by 37 · see citing works
Comparison of four different protocols of I-131 therapy for treating single toxic thyroid nodule
Zakavi, S. R., Mousavi, Z., & Davachi, B. (2009) · Nuclear Medicine Communications · doi:10.1097/mnm.0b013e3283169148 · Cited by 36 · see citing works
Goletti, O., Monzani, F., Caraccio, N., Guerra, P. D., Lippolis, P. V., Pucciarelli, M., Seccia, M., Carmassi, F., Cavina, E., & Baschieri, L. (1992) · World Journal of Surgery · doi:10.1007/bf02067387 · Cited by 36 · see citing works
Özdemir, B. H., Ilgit, E. T., Yücel, C., Atilla, S., Işık, S., Cakir, N., & Gökçora, N. (1994) · American Journal of Roentgenology · doi:10.2214/ajr.163.4.8092038 · Cited by 34 · see citing works
Managing toxic thyroid adenoma: a cost-effectiveness analysis
Vidal-Trecan, G. M., Stahl, J., & Durand‐Zaleski, I. (2002) · European Journal of Endocrinology · doi:10.1530/eje.0.1460283 · Cited by 31 · see citing works
Brkljačić, B., Sucic, M., Božikov, V., Hauser, M., & Hebrang, A. (2001) · Acta Radiologica · doi:10.1034/j.1600-0455.2001.420508.x · Cited by 29 · see citing works
Effect of radioiodine therapy on thyroid nodule size and function in patients with toxic adenomas
Erdoğan, M. F., Küçük, Ö., Anl, C., Aras, S., Özer, D., Araş, G., & Kamel, N. (2004) · Nuclear Medicine Communications · doi:10.1097/00006231-200411000-00003 · Cited by 24 · see citing works
Plummer’s disease: localized thyroid autonomy
Wiener, J. D. (1987) · Journal of Endocrinological Investigation · doi:10.1007/bf03347193 · Cited by 23 · see citing works
Determinants of Long-Term Outcome after Radioiodine Therapy for Solitary Autonomous Thyroid Nodules
Bolusani, H., Okosieme, O. E., Velagapudi, M., Parsons, K. E., & Lazarus, J. H. (2008) · Endocrine Practice · doi:10.4158/ep.14.5.543 · Cited by 21 · see citing works
Reschini, E., Matheoud, R., Canzi, C., Castellani, M., Galelli, M., Ferrari, G. C., PARACCHI, A., & Gerundini, P. (1999) · PubMed · Cited by 19 · see citing works
Estour, B., Millot, L., Vergely, N., Clavier, A., D'Hondt, O., CAILLOT, A., Brulport, V., DESCOUSUS, M., & DUBOIS, F. (1997) · Thyroid · doi:10.1089/thy.1997.7.357 · Cited by 18 · see citing works
Nygaard, B. (1998) · Thyroid · doi:10.1089/thy.1998.8.223 · Cited by 17 · see citing works
Outcome of radioactive iodine therapy in Toxic Nodular Goiter in Pakistan
Ahmad, T., Khoja, A. A., Rashid, N. H., & Ashfaq, M. A. (2018) · Pakistan Journal of Medical Sciences · doi:10.12669/pjms.345.15244 · Cited by 16 · see citing works
Hodax, J. K., Reinert, S. E., & Quintos, J. B. (2015) · Endocrine Practice · doi:10.4158/ep15905.or · Cited by 16 · see citing works
Thyrotoxicosis of other Etiologies
Kopp, P. A. (2010) · Cited by 17 · see citing works
Ronga, G., Filesi, M., D’Apollo, R., Toteda, M., Nicola, A. D. D., Colandrea, M., Travascio, L., Vestri, A. R., & Montesano, T. (2013) · Clinical Nuclear Medicine · doi:10.1097/rlu.0b013e318286bbda · Cited by 14 · see citing works
Long term thyroid function after 131I treatment for toxic adenoma
Tzavara, I., Tzanela, M., Vlassopoulou, B., Kouyioumoutzakis, G., Alevizaki, C., & Thalassinos, N. (2002) · HORMONES · doi:10.14310/horm.2002.1157 · Cited by 13 · see citing works
Thyroid Disease in the Emergency Department
Mitchell, J. M. (1989) · Emergency Medicine Clinics of North America · doi:10.1016/s0733-8627(20)30323-0 · Cited by 13 · see citing works
Percutaneous ethanol injection therapy for autonomously functioning thyroid nodule
Nakada, K., Katoh, C., Kanegae, K., Tsukamoto, E., Itoh, K., & Tamaki, N. (1996) · Annals of Nuclear Medicine · doi:10.1007/bf03165389 · Cited by 13 · see citing works
Weber, C. A., & Clark, O. H. (1985) · Medical Clinics of North America · doi:10.1016/s0025-7125(16)31008-2 · Cited by 13 · see citing works
INTENZO, C. M., Jabbour, S., Miller, J. L., Ahmed, I., Furlong, K., Kushen, M. C., Kim, S. M., & Capuzzi, D. M. (2011) · Clinical Nuclear Medicine · doi:10.1097/rlu.0b013e3182175477 · Cited by 12 · see citing works
Nygaard, B., Jarløv, A. E., Hegedűs, L. D., Schaadt, B. K., Kristensen, L. Ø., & Hansen, J. (1994) · Thyroid · doi:10.1089/thy.1994.4.167 · Cited by 12 · see citing works
Ertürk, M. S., Çekiç, B., Çelik, M., & Uğuz, I. D. (2020) · Endokrynologia Polska · doi:10.5603/ep.a2020.0088 · Cited by 12 · see citing works
Percutaneous Ethanol Injection of Benign Thyroid Nodules and Cysts using Ultrasound
Papini, E., & Pacella, C. M. (2000) · Springer eBooks · doi:10.1007/978-1-4757-3202-3_11 · Cited by 10 · see citing works
Dederichs, B., Otte, R., Klink, J. E., & Schicha, H. (1996) · Nuklearmedizin - NuclearMedicine · doi:10.1055/s-0038-1629802 · Cited by 10 · see citing works
Clinical aspects of hyperthyroidism in hospitalised patients in Albania
Agaçi, F. (2004) · HORMONES · doi:10.14310/horm.2002.11112 · Cited by 8 · see citing works
Prevalence of inappropriate drug treatment in patients with hyperthyroidism.
Cooke, S. G., Ratcliffe, G. E., Fogelman, I., & Maisey, M. N. (1985) · BMJ · doi:10.1136/bmj.291.6507.1491 · Cited by 8 · see citing works
Pedersen‐Bjergaard, U., & KIRKEGAARD, C. (1998) · European Journal of Endocrinology · doi:10.1530/eje.0.1390587 · Cited by 7 · see citing works
Thyroid hormones and antithyroid drugs
Bouillon, R. (1985) · Side effects of drugs annual · doi:10.1016/s0378-6080(85)80047-7 · Cited by 6 · see citing works
Radioiodine-treatment (RIT) of functional thyroidal autonomy.
Meller, J., Sahlman, C. O., & Becker, W. (2002) · PubMed · Cited by 6 · see citing works
Subclinical hyperthyroidism in the course of autonomous nodules — clinical evaluation
Rudzki, G., Lenart-Lipińska, M., Smoleń, A., Chrapko, B. E., & Matyjaszek‐Matuszek, B. (2019) · Endokrynologia Polska · doi:10.5603/ep.a2018.0088 · Cited by 4 · see citing works
Mazzaferri, E. L. (2006) · Yearbook of Endocrinology · doi:10.1016/s0084-3741(08)70374-3 · Cited by 4 · see citing works
Management of adenomas and toxic multinodular goiters with Iodine 131
Racaru, L. V., Grunenwald, S., Hindié, E., Taïeb, D., Clerc, J., & Zerdoud, S. (2020) · Médecine Nucléaire · doi:10.1016/j.mednuc.2020.09.001 · Cited by 4 · see citing works
Ethanol instillation of adenoma of the thyroid gland — a five-year experience
Blank, W., & Braun, B. (1998) · Minimally Invasive Therapy & Allied Technologies · doi:10.3109/13645709809152907 · Cited by 4 · see citing works
Long-Term Follow-up of Patients With Autonomous Thyroid Nodules Treated With Radioiodine
Moroto, D., Torquato-Vieira, I. C. O., Fiorin, L. B., Camacho, C. P., Castiglioni, M. L. V., Maciel, R. M. B., Furlanetto, R. P., Matsumura, L. K., Janovsky, C. C. P. S., Lindsey, S. C., et al. (2024) · Clinical Nuclear Medicine · doi:10.1097/rlu.0000000000005189 · Cited by 3 · see citing works
Spontanverlauf von kompensierten autonomen Schilddrüsenadenomen
Schaller, U. C., Hölzel, D., Kirsch, C., & Engelhardt, D. (1991) · Journal of Molecular Medicine · doi:10.1007/bf01744269 · Cited by 3 · see citing works
Aktolun, C., & Urhan, M. (2012) · Springer eBooks · doi:10.1007/978-1-4614-4021-5_17 · Cited by 3 · see citing works
McDougall, I. R. (1992) · Springer eBooks · doi:10.1007/978-1-4899-2881-8_5 · Cited by 3 · see citing works
Recurrent transient thyrotoxicosis in multinodular goitre
Arem, R. (1990) · Postgraduate Medical Journal · doi:10.1136/pgmj.66.771.54 · Cited by 3 · see citing works
Management of the Various Causes of Thyrotoxicosis
Ross, D. S. (1997) · Humana Press eBooks · doi:10.1007/978-1-4757-2594-0_10 · Cited by 2 · see citing works
McDermott, M., & Ridgway, E. C. (2009) · CRC Press eBooks · doi:10.3109/9781420070651-5 · Cited by 2 · see citing works
Nodular toxic goiter in children: clinical features, morphological variants
Евгеньевна, И. Т., Bezlepkina, O. B., Магомедовна, А. Ф., AIu, A., Degtyarev, M. V., & Zubkova, N. A. (2021) · Problems of Endocrinology · doi:10.14341/probl12738 · Cited by 2 · see citing works
Value of Thyroid Follow-up Registers
Falkenberg, M. G. K., Nilsson, O. R., & Rosenqvist, U. (1987) · Scandinavian Journal of Primary Health Care · doi:10.3109/02813438709014001 · Cited by 2 · see citing works
Hyperthyroidism Due to Graves’ Disease, Toxic Nodules and Toxic Multinodular Goiter
Burman, K. D. (2009) · CRC Press eBooks · doi:10.3109/9781420070651-3 · Cited by 1 · see citing works
Risk of booking for a home birth
Franklin, O. G., & Iliffe, S. (1986) · BMJ · doi:10.1136/bmj.292.6514.203-a · Cited by 1 · see citing works
Management of the Various Causes of Thyrotoxicosis
Ross, D. S. (2003) · Humana Press eBooks · doi:10.1007/978-1-59259-352-1_9 · Cited by 1 · see citing works
Thyroid Function and Disease in the Female
Emerson, C. H. (1987) · Springer eBooks · doi:10.1007/978-1-4613-2157-6_7 · Cited by 1 · see citing works
Tumores de la glándula tiroidea
Trotoux, J., & Aidan, D. (2000) · EMC - Otorrinolaringología · doi:10.1016/s1632-3475(00)71976-x
HOME | SEARCH | CURRENT ISSUE | PAST ISSUES | COLLECTIONS | HELP
Weinmann, E. E., & Salzman, E. W. (2004)
CLINICAL STUDY OF AUTONOMOUSLY FUNCTIONING THYROID NODULES (AFTN)
Suzuki, S., Tsuchiya, A., Seiji, E. N. D. O., Suzuki, M., Takita, K.-I., & Abe, R. (1992) · The journal of the Japanese Practical Surgeon Society · doi:10.3919/ringe1963.53.1257
Dederichs, B., Klink, J. E., Otte, R., & Schicha, H. (1997) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-7772-5_87
8 Surgical Management of Benign Thyroid Diseases
(2009) · Thieme eBooks · doi:10.1055/b-0034-73495
Moser, E. (1999) · Langenbecks Archiv für Chirurgie. Supplement · doi:10.1007/978-3-642-60248-1_4
Thyroid Peroxidase Antibodies in Non-Autoimmune Hyperthyroidism Treated with Radioactive Iodine
Listewnik, M. H., Listewnik, M. H., Miazgowski, T., Jaskólska, K., Jasiakiewicz, K., & Birkenfeld, B. (2016) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0042-113124
The Role of Surgery for Nodular Hyperthyroidism
Elfenbein, D. M., & Schneider, D. F. (2017) · Springer eBooks · doi:10.1007/978-3-319-43618-0_9
Autonomously Functioning Thyroid Nodules and Other Causes of Thyrotoxicosis
HENNEMANN, G. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5583-9.00082-4
Thyroid Nodules Following Neck Irradiation
Mazzaferri, E. L. (1989) · Springer eBooks · doi:10.1007/978-1-4615-6716-5_9
Therapie der Hyperthyreose: pro Operation
Wahl, R. A., Horas, U., Hornstein, R., & Labus, M. (1992) · European surgery. Supplement/European surgery · doi:10.1007/bf02601958
(2006) · Springer eBooks · doi:10.1007/1-84628-006-0_4
Prevalence of inappropriate drug treatment in patients with hyperthyroidism
Maisey, M. N., Fogelman, I., Cooke, S. G., & Ratcliffe, G. E. (1986) · BMJ · doi:10.1136/bmj.292.6514.202-d
Huang, S. A. (2007) · Springer eBooks · doi:10.1007/978-0-387-32322-0_3
Thyroid Function after Treatment of Solitary Autonomous Thyroid Nodules
(1984) · New England Journal of Medicine · doi:10.1056/nejm198405243102119
Mazzaferri, E. L. (2006) · Yearbook of Medicine · doi:10.1016/s0084-3873(08)70609-6
Alkoholinjektion in autonome Schilddrüsenbezirke: 5-Jahres-Ergebnisse
Blank, W., & Braun, B. (2000) · De Gruyter eBooks · doi:10.1515/9783110812282.469
Monzani, F., Guerra, P. D., Caraccio, N., Goletti, O., & Baschieri, L. (1993) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1993.tb00528.x
- Authors
- Goldstein, R., & Hart, I. R.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1983-12-15
- Volume
- 309
- Issue
- 24
- Pages
- 1473-1476
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2341027997
- Cited by
- 104
- References
- 14
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 2 · 2013: 1 · 2012: 1
- FWCI
- 2.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
- Keywords
- autonomously functioning thyroid nodules, iodine-131 therapy, long-term follow-up, hypothyroidism, nodule size, thyroid function, radioiodine therapy
- MeSH terms
- Adenoma, Adult, Evaluation Studies as Topic, Female, Follow-Up Studies, Humans, Hypothyroidism, Iodine Radioisotopes, Male, Middle Aged, Radiotherapy Dosage, Thyroid Diseases, Thyroid Gland, Thyroid Neoplasms
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
