The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Serum Osmolality: Uses and Limitations
Abstract
The serum osmolality measurement has a clearly circumscribed use in clinical medicine. Comparison of the measured osmolality with the osmolality calculated from the concentrations of the major solutes in serum gives information about large deviations in the serum water content. In addition, comparison of the measured and calculated values of osmolality provides rapid screening information about the presence of foreign low-molecular-weight solutes in the blood. Taken at face value, the test cannot be used to determine whether abnormalities in tonicity homeostasis are present. A simple and direct way to assess whether tonicity is normal is to calculate the effective osmolality from the concentrations of sodium and glucose in serum. With rare exceptions, this calculation provides the information needed to make decisions about therapy.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Dorwart, W. V., & Chalmers, L. (1975) · Clinical Chemistry · doi:10.1093/clinchem/21.2.190 · Cited by 184
Cited by
Biological variation and diagnostic accuracy of dehydration assessment markers
Cheuvront, S. N., Ely, B. R., Kenefick, R. W., & Sawka, M. N. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.29490 · Cited by 367
Body Fluid Dynamics: Back to the Future
Bhave, G., & Neilson, E. G. (2011) · Journal of the American Society of Nephrology · doi:10.1681/asn.2011080865 · Cited by 215
Plasma Hypertonicity: Another Marker of Frailty?
Stookey, J. D., Purser, J. L., Pieper, C. F., & Cohen, H. J. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52361.x · Cited by 80
Validation of equations used to predict plasma osmolality in a healthy adult cohort
Heavens, K. R., Kenefick, R. W., Caruso, E. M., Spitz, M. G., & Cheuvront, S. N. (2014) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.091009 · Cited by 60
Metadata
- Authors
- Gennari, F. J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1984-01-12
- Volume
- 310
- Issue
- 2
- Pages
- 102-105
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2076048951
- Cited by
- 279
- References
- 1
- FWCI
- 9.87
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Serum Osmolality: Uses and Limitations. https://app.cochat.ai/papers/10.1056/nejm198401123100207
- The paper
- Gennari, F. J. (1984). Serum Osmolality: Uses and Limitations. New England Journal of Medicine. https://doi.org/10.1056/nejm198401123100207
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
