Body Fluid Dynamics: Back to the Future

Bhave, Gautam; Neilson, Eric G.

doi:10.1681/asn.2011080865

Cited by 215Ion Transport and Channel RegulationElectrolyte and hormonal disordersChemical and Physical Studies

Body Fluid Dynamics: Back to the Future

Open access

Bhave, Gautam, Neilson, Eric G.·2011·Journal of the American Society of Nephrology

DOI 10.1681/asn.2011080865PMC PMC4096826

Open this paper in CoChat — free account

Abstract

Pioneering investigations conducted over a half century ago on tonicity, transcapillary fluid exchange, and the distribution of water and solute serve as a foundation for understanding the physiology of body fluid spaces. With passage of time, however, some of these concepts have lost their connectivity to more contemporary information. Here we examine the physical forces determining the compartmentalization of body fluid and its movement across capillary and cell membrane barriers, drawing particular attention to the interstitium operating as a dynamic interface for water and solute distribution rather than as a static reservoir. Newer work now supports an evolving model of body fluid dynamics that integrates exchangeable Na(+) stores and transcapillary dynamics with advances in interstitial matrix biology.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1681/asn.2011080865

Cites

188 of 188 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

There appears to be equivalent losses of plasma volume between the sexes under similar exercise conditions potentially representing sex differences in the compartmentalization of fluids.
“there appears to be equivalent losses of plasma volume between the sexes under similar exercise conditions [272,273] potentially representing sex differences in the compartmentalization of fluids.”
From International society of sports nutrition position stand: nutritional concerns of the female athlete (2023) · cites this paper as [273]
The Compartmentalization of Body Water section describes differences in fluid distribution between men and women, but does not compare plasma-volume losses during exercise. A search for equivalent losses under similar exercise conditions found no passage addressing that claim in our copy. Page numbers were not available. (LLM, conf=0.74)
Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Thermodynamic analysis of the permeability of biological membranes to non-electrolytes
Kedem, O., & Katchalsky, A. (1958) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(58)90330-5 · Cited by 2,214 · see citing works
On the Absorption of Fluids from the Connective Tissue Spaces
Starling, E. H. (1896) · The Journal of Physiology · doi:10.1113/jphysiol.1896.sp000596 · Cited by 2,126 · see citing works
MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function
Iozzo, R. V. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.609 · Cited by 1,639 · see citing works
Total body water volumes for adult males and females estimated from simple anthropometric measurements
Watson, P. E., Watson, I. D., & Rd, B. (1980) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/33.1.27 · Cited by 1,477 · see citing works
The Structure and Function of the Endothelial Glycocalyx Layer
Weinbaum, S., Tarbell, J. M., & Damiano, E. R. (2007) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.9.060906.151959 · Cited by 1,204 · see citing works
Microvascular fluid exchange and the revised Starling principle
Levick, J. R., & Michel, C. C. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq062 · Cited by 1,183 · see citing works
Salt intakes around the world: implications for public health
Brown, I. J., Tzoulaki, I., Candeias, V., & Elliott, P. (2009) · International Journal of Epidemiology · doi:10.1093/ije/dyp139 · Cited by 1,173 · see citing works
Clinical Physiology of Acid-Base and Electrolyte Disorders
(1990) · Annals of Internal Medicine · doi:10.7326/0003-4819-113-2-176_8 · Cited by 1,152 · see citing works
A syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone
Schwartz, W. B., Bennett, W. A., Curelop, S., & Bartter, F. C. (1957) · The American Journal of Medicine · doi:10.1016/0002-9343(57)90224-3 · Cited by 1,151 · see citing works
A Triphasic Theory for the Swelling and Deformation Behaviors of Articular Cartilage
Lai, W. M., Hou, J., & Mow, V. C. (1991) · Journal of Biomechanical Engineering · doi:10.1115/1.2894880 · Cited by 1,131 · see citing works
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism
Machnik, A., Neuhofer, W., Jantsch, J., Dahlmann, A., Tammela, T., Machura, K., Park, J.-K., Beck, F.-X., Müller, D. N., Derer, W., et al. (2009) · Nature Medicine · doi:10.1038/nm.1960 · Cited by 953 · see citing works
Interstitial-lymphatic mechanisms in the control of extracellular fluid volume
Aukland, K., & Reed, R. K. (1993) · Physiological Reviews · doi:10.1152/physrev.1993.73.1.1 · Cited by 938 · see citing works
Balance between swelling pressure and collagen tension in normal and degenerate cartilage
Maroudas, A. (1976) · Nature · doi:10.1038/260808a0 · Cited by 726 · see citing works
A Physical Interpretation of the Phenomenological Coefficients of Membrane Permeability
Kedem, O., & Katchalsky, A. (1961) · The Journal of General Physiology · doi:10.1085/jgp.45.1.143 · Cited by 718 · see citing works
The Body Cell Mass and Its Supporting Environment
BOUMAN, H. D. (1963) · Physical Therapy · doi:10.1093/ptj/43.9.695a · Cited by 629 · see citing works
Regulation of cellular volume.
Macknight, A. D. C., & Leaf, A. (1977) · Physiological Reviews · doi:10.1152/physrev.1977.57.3.510 · Cited by 603 · see citing works
Basic anatomical and physiological data for use in radiological protection: reference values. A report of age- and gender-related differences in the anatomical and physiological characteristics of reference individuals. ICRP Publication 89.
(2002) · PubMed · Cited by 600 · see citing works
Interstitial fluid pressure
Guyton, A. C., Granger, H. J., & Taylor, A. E. (1971) · Physiological Reviews · doi:10.1152/physrev.1971.51.3.527 · Cited by 567 · see citing works
Hyponatremia: evaluating the correction factor for hyperglycemia
Hillier, T. A., Abbott, R. D., & Barrett, E. J. (1999) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)00055-8 · Cited by 567 · see citing works
Transport of macromolecules across microvascular walls: the two-pore theory
Rippe, B., & Haraldsson, B. S. (1994) · Physiological Reviews · doi:10.1152/physrev.1994.74.1.163 · Cited by 564 · see citing works
The theory of measurement of osmotic pressure
Staverman, A. J. (1951) · Recueil des Travaux Chimiques des Pays-Bas · doi:10.1002/recl.19510700409 · Cited by 548 · see citing works
Anatomy of body water and electrolytes
Edelman, I. S., & Leibman, J. (1959) · The American Journal of Medicine · doi:10.1016/0002-9343(59)90346-8 · Cited by 474 · see citing works
Human Body Composition: Growth, Aging, Nutrition, and Activity
Forbes, G. B. (1987) · Medical Entomology and Zoology · Cited by 461 · see citing works
Human Body Composition
Forbes, G. B. (1987) · doi:10.1007/978-1-4612-4654-1 · Cited by 431 · see citing works
THE CHONDROCYTE: A CELL UNDER PRESSURE
Urban, J. (1994) · Lara D. Veeken · doi:10.1093/rheumatology/33.10.901 · Cited by 430 · see citing works
Interstitial fluid volume: local regulatory mechanisms.
Aukland, K., & Nicolaysen, G. (1981) · Physiological Reviews · doi:10.1152/physrev.1981.61.3.556 · Cited by 404 · see citing works
Sodium and potassium intake and balance in adults consuming self-selected diets
Holbrook, J. T., Patterson, K. Y., Bodner, J. E., Douglas, L. W., Veillon, C., Kelsay, J., Mertz, W., & Smith, J. (1984) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/40.4.786 · Cited by 396 · see citing works
Clinical Disorders of Fluid and Electrolyte Metabolism
(1964) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1964.tb133951.x · Cited by 392 · see citing works
THE COMPOSITION OF THE ADULT HUMAN BODY AS DETERMINED BY CHEMICAL ANALYSIS
Forbes, R. M., Cooper, A. R., & Mitchell, H. H. (1953) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52646-1 · Cited by 389 · see citing works
A Concept of Negative Interstitial Pressure Based on Pressures in Implanted Perforated Capsules
Guyton, A. C., Frank, M., & Abernathy, B. (1963) · Circulation Research · doi:10.1161/01.res.12.4.399 · Cited by 385 · see citing works
Reassessment of Albumin as a Nutritional Marker in Kidney Disease
Friedman, A. N., & Fadem, S. Z. (2010) · Journal of the American Society of Nephrology · doi:10.1681/asn.2009020213 · Cited by 361 · see citing works
Cardiovascular and humoral responses to extremes of sodium intake in normal black and white men.
Luft, F. C., Rankin, L. I., Bloch, R., Weyman, A. E., Willis, L. R., Murray, R. H., Grim, C. E., & Weinberger, M. H. (1979) · Circulation · doi:10.1161/01.cir.60.3.697 · Cited by 352 · see citing works
Water and Electrolyte Metabolism
Manery, J. F. (1954) · Physiological Reviews · doi:10.1152/physrev.1954.34.2.334 · Cited by 341 · see citing works
Glycosaminoglycan polymerization may enable osmotically inactive Na+storage in the skin
Titze, J. M., Shakibaei, M., Schafflhuber, M., Schulze-Tanzil, G. G., Porst, M., Schwind, K. H., Dietsch, P., & Hilgers, K. F. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01237.2003 · Cited by 329 · see citing works
Oncotic pressures opposing filtration across non‐fenestrated rat microvessels
Adamson, R. H., Lenz, J. F., Zhang, X., Adamson, G. N., Weinbaum, S., & CURRY, F. E. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2003.058255 · Cited by 323 · see citing works
Distribution and Diffusion of Solutes in Articular Cartilage
Maroudas, A. (1970) · Biophysical Journal · doi:10.1016/s0006-3495(70)86307-x · Cited by 316 · see citing works
TOTAL SODIUM, POTASSIUM AND CHLORIDE IN ADULT MAN 1
Forbes, G. B., & Lewis, A. M. (1956) · Journal of Clinical Investigation · doi:10.1172/jci103313 · Cited by 312 · see citing works
Composition of trabecular and cortical bone
Gong, J. K., Arnold, J. S., & Cohn, S. H. (1964) · The Anatomical Record · doi:10.1002/ar.1091490303 · Cited by 311 · see citing works
On the mechanism of fluid exchange of tissues in vitro
Leaf, A. (1956) · Biochemical Journal · doi:10.1042/bj0620241 · Cited by 310 · see citing works
The Influence of Short-Chain Alcohols on Interfacial Tension, Mechanical Properties, Area/Molecule, and Permeability of Fluid Lipid Bilayers
Ly, H. V., & Longo, M. L. (2004) · Biophysical Journal · doi:10.1529/biophysj.103.034280 · Cited by 306 · see citing works
A driving force for change: interstitial flow as a morphoregulator
Rutkowski, J. M., & Swartz, M. A. (2006) · Trends in Cell Biology · doi:10.1016/j.tcb.2006.11.007 · Cited by 303 · see citing works
Interstitial Flow as a Guide for Lymphangiogenesis
Boardman, K. C., & Swartz, M. A. (2003) · Circulation Research · doi:10.1161/01.res.0000065621.69843.49 · Cited by 289 · see citing works
Interstitial Fluid Pressure: II. Pressure-Volume Curves of Interstitial Space
Guyton, A. C. (1965) · Circulation Research · doi:10.1161/01.res.16.5.452 · Cited by 288 · see citing works
High dietary sodium chloride consumption may not induce body fluid retention in humans
Heer, M., Baisch, F., Kropp, J., Gerzer, R., & Drummer, C. (2000) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.2000.278.4.f585 · Cited by 285 · see citing works
Serum Osmolality
Gennari, F. J. (1984) · New England Journal of Medicine · doi:10.1056/nejm198401123100207 · Cited by 280 · see citing works
Albumin-Deficient Rat Mutant
Nagase, S., Shimamune, K., & Shumiya, S. (1979) · Science · doi:10.1126/science.451621 · Cited by 277 · see citing works
Mechanical Properties of the Collagen Network in Human Articular Cartilage as Measured by Osmotic Stress Technique
Basser, P. J., Schneiderman, R. S., Bank, R. A., Wachtel, E. J., & Maroudas, A. (1998) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1997.0507 · Cited by 267 · see citing works
Salt-Sensitive Essential Hypertension in Men
Kurtz, T. W., Al-Bander, H. A., & Morris, R. C. (1987) · New England Journal of Medicine · doi:10.1056/nejm198710223171702 · Cited by 264 · see citing works
The Regulation of Extracellular Fluid Volume
Gauer, O. H., Henry, J. P., & Behn, C. (1970) · Annual Review of Physiology · doi:10.1146/annurev.ph.32.030170.002555 · Cited by 263 · see citing works
Plasmin in Nephrotic Urine Activates the Epithelial Sodium Channel
Svenningsen, P., Bistrup, C., Friis, U. G., Bertog, M., Haerteis, S., Krueger, B., Stubbe, J., Jensen, O. N., Thiesson, H. C., Uhrenholt, T. R., et al. (2008) · Journal of the American Society of Nephrology · doi:10.1681/asn.2008040364 · Cited by 262 · see citing works
Cellular volume homeostasis
Strange, K. B. (2004) · AJP Advances in Physiology Education · doi:10.1152/advan.00034.2004 · Cited by 255 · see citing works
Effect of insulin on the distribution and disposition of glucose in man.
Ferrannini, E., Smith, J. D., Cobelli, C., Toffolo, G., Pilo, A., & DeFronzo, R. A. (1985) · Journal of Clinical Investigation · doi:10.1172/jci111969 · Cited by 254 · see citing works
Role for intrarenal mechanisms in the impaired salt excretion of experimental nephrotic syndrome.
Ichikawa, I., Rennke, H. G., Hoyer, J. R., Badr, K. F., Schor, N., Troy, J. L., Lechène, C., & Brenner, B. M. (1983) · Journal of Clinical Investigation · doi:10.1172/jci110756 · Cited by 249 · see citing works
Water Permeability of Thin Lipid Membranes
Cass, A., & Finkelstein, A. (1967) · The Journal of General Physiology · doi:10.1085/jgp.50.6.1765 · Cited by 247 · see citing works
The Permeability of Brain Capillaries to Non‐Electrolytes
Crone, C. (1965) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1965.tb04198.x · Cited by 243 · see citing works
The Donnan Equilibrium
Overbeek, J. T. G. (1956) · Progress in Biophysics and Biophysical Chemistry · doi:10.1016/s0096-4174(18)30104-5 · Cited by 239 · see citing works
Transcapillary exchange: Role and importance of the interstitial fluid pressure and the extracellular matrix
Reed, R. K., & Rubin, K. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq143 · Cited by 209 · see citing works
ICRP. Introduction to the ICRP Publication 70, "Basic Anatomical and Physiological Data for Use in Radiological Protection: The Skeleton".
Kawamura, H. (1996) · Japanese Journal of Health Physics · doi:10.5453/jhps.31.418 · Cited by 209 · see citing works
Relative expansion of extracellular fluid in obese vs. nonobese women
Waki, M., Kral, J. G., Mazariegos, M., Wang, J., Pierson, R. N., & Heymsfield, S. B. (1991) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1991.261.2.e199 · Cited by 203 · see citing works
Filtration and reflection coefficients of the rabbit blood-brain barrier
Fenstermacher, J. D., & Johnson, J. (1966) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1966.211.2.341 · Cited by 199 · see citing works
Measurement of swelling pressure in cartilage and comparison with the osmotic pressure of constituent proteoglycans
Maroudas, A., & Bannon, C. (1981) · Biorheology · doi:10.3233/bir-1981-183-624 · Cited by 197 · see citing works
Gross tissue weights in the human body by cadaver dissection.
Clarys, J. P., Martin, A. D., & Drinkwater, D. T. (1984) · PubMed · Cited by 197 · see citing works
THE MEASUREMENT OF EXCHANGEABLE POTASSIUM IN MAN BY ISOTOPE DILUTION 1
Corsa, L., Olney, J. M., Steenburg, R. W., BALL, M. R., & Moore, F. D. (1950) · Journal of Clinical Investigation · doi:10.1172/jci102365 · Cited by 195 · see citing works
Capillary filtration‐absorption balance reconsidered in light of dynamic extravascular factors
Levick (1991) · Experimental Physiology · doi:10.1113/expphysiol.1991.sp003549 · Cited by 180 · see citing works
Language Guiding Therapy: The Case of Dehydration versus Volume Depletion
Mange, K. C., Matsuura, D., Cizman, B., Soto, H., Ziyadeh, F. N., Goldfarb, S., & Neilson, E. G. (1997) · Annals of Internal Medicine · doi:10.7326/0003-4819-127-9-199711010-00020 · Cited by 176 · see citing works
Self-citation
Urea permeability of mammalian inner medullary collecting duct system and papillary surface epithelium.
Sands, J. M., & Knepper, M. A. (1987) · Journal of Clinical Investigation · doi:10.1172/jci112774 · Cited by 171 · see citing works
Role of bone in regulation of systemic acid-base balance
Green, J., & Kleeman, C. R. (1991) · Kidney International · doi:10.1038/ki.1991.2 · Cited by 167 · see citing works
Trends in 24-h urinary sodium excretion in the United States, 1957–2003: a systematic review
Bernstein, A. M., & Willett, W. C. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.29367 · Cited by 166 · see citing works
Activity of water in aqueous systems; A frequently neglected property
Blandamer, M. J., Engberts, J. B. F. N., Gleeson, P. T., & Reis, J. C. R. (2005) · Chemical Society Reviews · doi:10.1039/b400473f · Cited by 164 · see citing works
Brain swelling after dialysis: old urea or new osmoles
Silver, S. M., Sterns, R. H., & Halperin, M. L. (1996) · American Journal of Kidney Diseases · doi:10.1016/s0272-6386(96)90124-9 · Cited by 162 · see citing works
CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. VI. THE OSMOTIC PRESSURE OF PLASMA AND OF SERUM ALBUMIN 12
Scatchard, G., Batchelder, A. C., & Brown, A. (1944) · Journal of Clinical Investigation · doi:10.1172/jci101513 · Cited by 160 · see citing works
Dietary Chloride as a Determinant of "Sodium-Dependent" Hypertension
Kurtz, T. W., & Morris, R. C. (1983) · Science · doi:10.1126/science.6648527 · Cited by 156 · see citing works
Total body water reference values and prediction equations for adults
Chumlea, W. C., Guo, S. S., Zeller, C. M., Reo, N. V., Baumgartner, R. N., Garry, P. J., Wang, J., Pierson, R. N., Heymsfield, S. B., & Siervogel, R. M. (2001) · Kidney International · doi:10.1046/j.1523-1755.2001.00741.x · Cited by 152 · see citing works
Some consequences of capillary permeability to macromolecules: Starling's hypothesis reconsidered
Renkin, E. M. (1986) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1986.250.5.h706 · Cited by 148 · see citing works
Commentary on ‘Thermodynamic analysis of the permeability of biological membranes to non-electrolytes’ by O. Kedem and A. Katchalsky Biochim. Biophys. Acta 27 (1958) 229–246
Kedem, O. (1989) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0006-3002(89)80036-8 · Cited by 147 · see citing works
Starling forces that oppose filtration after tissue oncotic pressure is increased
Hu, X., Adamson, R. H., Liu, B., CURRY, F. E., & Weinbaum, S. (2000) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2000.279.4.h1724 · Cited by 143 · see citing works
ELECTROLYTE COMPOSITION OF BONE AND THE PENETRATION OF RADIOSODIUM AND DEUTERIUM OXIDE INTO DOG AND HUMAN BONE 12
Edelman, I. S., James, A. H., Baden, H. C., & Moore, F. D. (1954) · Journal of Clinical Investigation · doi:10.1172/jci102878 · Cited by 138 · see citing works
Reduced osmotically inactive Na storage capacity and hypertension in the Dahl model
Titze, J. M., Krause, H., Hecht, H., Dietsch, P., Rittweger, J., Lang, R., Kirsch, K. A., & Hilgers, K. F. (2002) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00323.2001 · Cited by 131 · see citing works
Sodium bicarbonate and sodium chloride: effects on blood pressure and electrolyte homeostasis in normal and hypertensive man
Luft, F. C., Zemel, M. B., Sowers, J. A., Fineberg, N. S., & Weinberger, M. H. (1990) · Journal of Hypertension · doi:10.1097/00004872-199007000-00010 · Cited by 130 · see citing works
Internal sodium balance in DOCA-salt rats: a body composition study
Titze, J. M., Bauer, K. H., Schafflhuber, M., Dietsch, P., Lang, R., Schwind, K. H., Luft, F. C., Eckardt, K., & Hilgers, K. F. (2005) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00096.2005 · Cited by 128 · see citing works
FURTHER STUDIES ON THE GROSS COMPOSITION AND MINERAL ELEMENTS OF THE ADULT HUMAN BODY
FORBES, R. M., Mitchell, H. H., & Cooper, A. R. (1956) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)65095-1 · Cited by 123 · see citing works
Decreased Effective Blood Volume in Edematous Disorders
Schrier, R. W. (2007) · Journal of the American Society of Nephrology · doi:10.1681/asn.2006111302 · Cited by 120 · see citing works
Limitations of methods of osmometry: measuring the osmolality of biological fluids
Sweeney, T. E., & Beuchat, C. A. (1993) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1993.264.3.r469 · Cited by 119 · see citing works
Blockade of beta 1-integrins in skin causes edema through lowering of interstitial fluid pressure.
Reed, R. K., Rubin, K., Wiig, H., & Rodt, S. Å. (1992) · Circulation Research · doi:10.1161/01.res.71.4.978 · Cited by 119 · see citing works
Serum Protein Electrophoresis: An Underused but Very Useful Test
Vavricka, S. R., Burri, E., Beglinger, C., Degen, L. P., & Manz, M. (2009) · Digestion · doi:10.1159/000212077 · Cited by 119 · see citing works
Disparate Hydration of Adipose and Lean Tissue Require a New Model for Body Water Distribution in Man
Wang, J. P., & Pierson, R. N. (1976) · Journal of Nutrition · doi:10.1093/jn/106.12.1687 · Cited by 118 · see citing works
THE DIRECT MEASUREMENT OF THE EXTRACELLULAR PHASE OF TISSUES 12
Nichols, G., Nichols, N., Weil, W. B., & Wallace, W. M. (1953) · Journal of Clinical Investigation · doi:10.1172/jci102858 · Cited by 113 · see citing works
Sodium Retention in Black and White Female Adolescents in Response to Salt Intake
Palacios, C. S., Wigertz, K., Martin, B. R., Jackman, L., Pratt, J. H., Peacock, M., McCabe, G. P., & Weaver, C. M. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031446 · Cited by 105 · see citing works
Extracellular volume: its structure and measurement and the influence of age and disease
Cheek, D. B. (1961) · The Journal of Pediatrics · doi:10.1016/s0022-3476(61)80068-1 · Cited by 104 · see citing works
Hyponatremia, Hyposmolality, and Hypotonicity
Oster, J. R., & Singer, I. I. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.4.333 · Cited by 102 · see citing works
Synthetic hydroxyapatite crystals
Neuman, W. F., & Mulryan, B. J. (1967) · Calcified Tissue International · doi:10.1007/bf02008079 · Cited by 101 · see citing works
Acute postburn edema: role of strongly negative interstitial fluid pressure
Lund, T., Wiig, H., & Reed, R. K. (1988) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1988.255.5.h1069 · Cited by 98 · see citing works
Osmotic reflextion coefficients of capillary walls to low molecular weight hydrophilic solutes measured in single perfused capillaries of the frog mesentery.
CURRY, F. E., Michel, C. C., & Mason, J. (1976) · The Journal of Physiology · doi:10.1113/jphysiol.1976.sp011561 · Cited by 97 · see citing works
A Multisolute Osmotic Virial Equation for Solutions of Interest in Biology
Elliott, J. A. W., Prickett, R. C., Elmoazzen, H., Porter, K. R., & McGann, L. E. (2007) · The Journal of Physical Chemistry B · doi:10.1021/jp0680342 · Cited by 97 · see citing works
Macromolecular basis of globular protein exclusion and of swelling pressure in loose connective tissue (Umbilical cord)
Meyer, F. A. (1983) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(83)90242-8 · Cited by 95 · see citing works
CHLORIDE, BROMIDE, SODIUM, AND SUCROSE SPACES IN MAN 1
Gamble, J. L., Robertson, J. S., Hannigan, C. A., Foster, C. G., & Farr, L. E. (1953) · Journal of Clinical Investigation · doi:10.1172/jci102764 · Cited by 94 · see citing works
Plasma Protein Measurements as a Diagnostic Aid
Alper, C. A. (1974) · New England Journal of Medicine · doi:10.1056/nejm197408082910606 · Cited by 93 · see citing works
Volume regulation in children with early relapse of minimal-change nephrosis with or without hypovolaemic symptoms
Walle, J. V., Donckerwolcke, R. A. M. G., van Isselt, J. W., Joles, J. A., Koomans, H. A., & Derkx, F. H. M. (1995) · The Lancet · doi:10.1016/s0140-6736(95)91210-x · Cited by 93 · see citing works
The pharmacokinetics of the interstitial space in humans
Levitt, D. G. (2003) · BMC Clinical Pharmacology · doi:10.1186/1472-6904-3-3 · Cited by 92 · see citing works
Set point for sodium homeostasis: Surfeit, deficit, and their implications
Hollenberg, N. K. (1980) · Kidney International · doi:10.1038/ki.1980.50 · Cited by 92 · see citing works
The Effects of Hemorrhage on Body Composition
Moore, F. D. (1965) · New England Journal of Medicine · doi:10.1056/nejm196509092731101 · Cited by 92 · see citing works
THE POTENTIAL OF WATER IN MAMMALIAN TISSUES
Maffly, R. H., & Leaf, A. (1959) · The Journal of General Physiology · doi:10.1085/jgp.42.6.1257 · Cited by 89 · see citing works
Congenital analbuminaemia: biochemical and clinical implications. A case report and literature review
Koot, B. G. P., Houwen, R. H. J., Pot, D. J., & Nauta, J. (2004) · European Journal of Pediatrics · doi:10.1007/s00431-004-1492-z · Cited by 87 · see citing works
THE FREEZING POINT DEPRESSION OF MAMMALIAN TISSUES AFTER SUDDEN HEATING IN BOILING DISTILLED WATER
Appelboom, J. W. T., Brodsky, W. A., Tuttle, W. S., & Diamond, I. (1958) · The Journal of General Physiology · doi:10.1085/jgp.41.6.1153 · Cited by 82 · see citing works
TOTAL BODY WATER AND TOTAL EXCHANGEABLE SODIUM IN EDEMATOUS STATES DUE TO CARDIAC, RENAL OR HEPATIC DISEASE 1
Färber, S. J., & Soberman, R. J. (1956) · Journal of Clinical Investigation · doi:10.1172/jci103330 · Cited by 79 · see citing works
Intracellular Monovalent Ions as Second Messengers
Orlov, S. N., & Hamet, P. (2006) · The Journal of Membrane Biology · doi:10.1007/s00232-006-0857-9 · Cited by 78 · see citing works
Uses and Limitations of the Balance Technique
Kopple, J. D. (1987) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/014860718701100511 · Cited by 77 · see citing works
Basic anatomical and physiological data for use in radiological protection: the skeleton. A report of a Task Group of Committee 2 of the International Commission on Radiological Protection.
(1995) · PubMed · Cited by 77 · see citing works
Sodium, potassium and water metabolism in the syndrome of inappropriate antidiuretic hormone secretion
Nolph, K. D., & Schrier, R. W. (1970) · The American Journal of Medicine · doi:10.1016/s0002-9343(70)80048-1 · Cited by 74 · see citing works
A Study of Ionic Equilibria in Cartilage
Maroudas, A., & Evans, H. (1972) · Connective Tissue Research · doi:10.3109/03008207209152058 · Cited by 74 · see citing works
A critique of the overfill hypothesis of sodium and water retention in the nephrotic syndrome
Schrier, R. W., & Fassett, R. G. (1998) · Kidney International · doi:10.1046/j.1523-1755.1998.00864.x · Cited by 72 · see citing works
Sodium-, potassium-, chloride-, and bicarbonate-related effects on blood pressure and electrolyte homeostasis in deoxycorticosterone acetate-treated rats
Ziomber, A., Machnik, A., Dahlmann, A., Dietsch, P., Beck, F.-X., Wagner, H., Hilgers, K. F., Luft, F. C., Eckardt, K., & Titze, J. M. (2008) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00531.2007 · Cited by 72 · see citing works
The analysis of the osmotic pressures of the serum proteins, and the molecular weights of albumins and globulins
Adair, G. S., & Robinson, M. E. (1930) · Biochemical Journal · doi:10.1042/bj0241864 · Cited by 72 · see citing works
Increasing sodium intake from a previous low or high intake affects water, electrolyte and acid–base balance differently
Heer, M., Frings-Meuthen, P., Titze, J., Boschmann, M., Frisch, S., Baecker, N., & Beck, L. (2009) · British Journal of Nutrition · doi:10.1017/s0007114508088041 · Cited by 69 · see citing works
Metabolic Changes Associated with Mitral Valvuloplasty
Wilson, G. M., Edelman, I. S., Brooks, L., MYRDEN, J. A., Harken, D. E., & Moore, F. D. (1954) · Circulation · doi:10.1161/01.cir.9.2.199 · Cited by 68 · see citing works
Compliance of the interstitial space in rats II. Studies on skin
Wiig, H., & Reed, R. K. (1981) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1981.tb06901.x · Cited by 67 · see citing works
The influence and interactions of hydrostatic and osmotic pressures on the intracellular milieu of chondrocytes
Browning, J., Saunders, K., Urban, J., & Wilkins, R. J. (2004) · Biorheology · doi:10.1177/0006355x2004041003004012 · Cited by 65 · see citing works
The Relationship of Total Exchangeable Potassium and Chloride to Lean Body Mass, Red Cell Mass and Creatinine Excretion in Man
Muldowney, F. P., Crooks, J., & Bluhm, M. M. (1957) · Journal of Clinical Investigation · doi:10.1172/jci103537 · Cited by 65 · see citing works
Reference man and woman more fully characterized
Ellis, K. J. (1990) · Biological Trace Element Research · doi:10.1007/bf02992693 · Cited by 65 · see citing works
Integrins: Sensors of Extracellular Matrix and Modulators of Cell Function
Pozzi, A., & Zent, R. (2003) · Nephron Experimental Nephrology · doi:10.1159/000072025 · Cited by 63 · see citing works
Can Dietary Sodium Intake Be Modified by Public Policy?
McCarron, D. A., Geerling, J. C., Kazaks, A., & Stern, J. S. (2009) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.04660709 · Cited by 63 · see citing works
Renal sodium handling in normal humans subjected to low, normal, and extremely high sodium supplies
Roos, J. C., Koomans, H. A., Mees, E. J. D., & Delawi, I. M. (1985) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.1985.249.6.f941 · Cited by 62 · see citing works
Body sodium and potassium. IV. The normal total exchangeable sodium; its measurement and magnitude.
Is, E., JAMES, A. H., Brooks, L., & Fd, M. (1954) · PubMed · Cited by 62 · see citing works
Regulation of proteoglycan synthesis rate in cartilage in vitro: influence of extracellular ionic composition
Urban, J., & Bayliss, M. T. (1989) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(89)90050-0 · Cited by 61 · see citing works
Adaptation of articular chondrocytes to changes in osmolality
Hopewell, B., & Urban, J. P. G. (2003) · Biorheology · doi:10.1177/0006355x2003040001003012 · Cited by 60 · see citing works
Renal sodium retention during volume expansion in experimental nephrotic syndrome
Bernard, D. B., ALEXANDER, E. A., Couser, W. G., & Levinsky, N. G. (1978) · Kidney International · doi:10.1038/ki.1978.152 · Cited by 60 · see citing works
Mechanisms behind increased dermal imbibition pressure in acute burn edema
Lund, T., Onarheim, H., Wiig, H., & Reed, R. K. (1989) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1989.256.4.h940 · Cited by 58 · see citing works
Measurement of Extracellular Fluid Volume in Nephrectomized Dogs1
Swan, R. C., Madisso, H., & Pitts, R. F. (1954) · Journal of Clinical Investigation · doi:10.1172/jci103023 · Cited by 57 · see citing works
Interstitial exclusion of albumin in rat dermis and subcutis in over- and dehydration
Reed, R. K., Lepsøe, S., & Wiig, H. (1989) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1989.257.6.h1819 · Cited by 56 · see citing works
An investigation into the cause of hyponatremia in the syndrome of inappropriate secretion of antidiuretic hormone
Kaye, M. (1966) · The American Journal of Medicine · doi:10.1016/0002-9343(66)90049-0 · Cited by 55 · see citing works
Plasma Composition in the Nephrotic Syndrome
Kaysen, G. A. (1993) · American Journal of Nephrology · doi:10.1159/000168649 · Cited by 54 · see citing works
Pathophysiology of Edema Formation in Children with Nephrotic Syndrome Not Due to Minimal Change Disease
Walle, J. V., Donckerwolcke, R. A. M. G., & Koomans, H. A. (1999) · Journal of the American Society of Nephrology · doi:10.1681/asn.v102323 · Cited by 54 · see citing works
Acute postburn edema: Role of strongly negative interstitial fluid pressure
Lund, T., Wiig, H., & Reed, R. K. (1989) · Journal of Critical Care · doi:10.1016/0883-9441(89)90039-7 · Cited by 53 · see citing works
The direct measurement of plasma colloid osmotic pressure is superior to colloid osmotic pressure derived from albumin or total protein
Barclay, S. A., & Bennett, D. (1987) · Intensive Care Medicine · doi:10.1007/bf00254796 · Cited by 52 · see citing works
Vascular Hyperpermeability in Nephrotic Edema
Rostoker, G., Behar, A., & Lagrue, G. (2000) · The Nephron journals/Nephron journals · doi:10.1159/000045661 · Cited by 51 · see citing works
Ion concentrations in subcutaneous interstitial fluid: measured versus expected values
Gilanyi, M., Ikrényi, C., Fekete, J. T., Ikrényi, K., & Kovach, A. (1988) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.1988.255.3.f513 · Cited by 51 · see citing works
The corrected protein equation to estimate plasma colloid osmotic pressure and its development on a nomogram.
Nitta, S., Ohnuki, T., Ohkuda, K., Nakada, T., & Staub, N. C. (1981) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.135.43 · Cited by 49 · see citing works
The variable hyponatremic response to hyperglycemia.
Morán, S., & Jamison, R. L. (1985) · PubMed Central · Cited by 46 · see citing works
Increased negativity of interstitial fluid pressure during the onset stage of inflammatory edema in rat skin
Reed, R. K., & Rodt, S. Å. (1991) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1991.260.6.h1985 · Cited by 46 · see citing works
Pathogenesis of edema formation in the nephrotic syndrome.
Palmer, B. F., & Alpern, R. J. (1997) · PubMed · Cited by 44 · see citing works
[Sodium-depositing function of the skin in white rats].
Ln, I., Vk, A., & Shterental', I. S. (1978) · PubMed · Cited by 44 · see citing works
Cell volume homeostasis: Ionic and nonionic mechanisms
Stein, W. D. (2002) · International review of cytology · doi:10.1016/s0074-7696(02)15011-x · Cited by 43 · see citing works
Bennhold's analbuminemia: A follow-up study of the first two cases (1953–1992)
Kallee, E. (1996) · Journal of Laboratory and Clinical Medicine · doi:10.1016/s0022-2143(96)90064-5 · Cited by 43 · see citing works
Relationships among protein and albumin concentrations and oncotic pressure in nephrotic plasma
Canaan‐Kühl, S., Venkatraman, E. S., Ernst, S. I., Olshen, R. A., & Myers, B. D. (1993) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.1993.264.6.f1052 · Cited by 43 · see citing works
Interstitial fluid pressure: Capsule, free fluid, gel fluid, and gel absorption pressure in subcutaneous tissue
Brace, R. A., & Guyton, A. C. (1979) · Microvascular Research · doi:10.1016/0026-2862(79)90030-x · Cited by 42 · see citing works
Permeability of rabbit heart capillaries to nonelectrolytes
Vargas, F., & Johnson, J. (1967) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1967.213.1.87 · Cited by 41 · see citing works
Renal sodium handling in children with nephrotic relapse: relation to hypovolaemic symptoms
Walle, J. V., Donckerwolcke, R. A. M. G., Greidanus, T. B. W., Joles, J. A., & Koomans, H. A. (1996) · Nephrology Dialysis Transplantation · doi:10.1093/oxfordjournals.ndt.a027137 · Cited by 40 · see citing works
In vivo determination of steric and electrostatic exclusion of albumin in rat skin and skeletal muscle
Gyenge, C. C., Tenstad, O., & Wiig, H. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.049379 · Cited by 38 · see citing works
Lowered Tissue-Fluid Oncotic Pressure Protects the Blood Volume in the Nephrotic Syndrome
Koomans, H. A., Geers, A. B., Mees, E. J. D., & Kortlandt, W. (2008) · The Nephron journals/Nephron journals · doi:10.1159/000183695 · Cited by 36 · see citing works
Measurement of osmotic reflection coefficient for small molecules in cat hindlimbs
Wolf, M. B., & WATSON, P. D. (1989) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1989.256.1.h282 · Cited by 33 · see citing works
Die Errechnung des kolloidosmotischen Serumdruckes aus dem Eiweiss-Spektrum und das mittlere Molekulargewicht der Serumeiweissfraktionen
Ott, H. (1956) · Journal of Molecular Medicine · doi:10.1007/bf01467572 · Cited by 32 · see citing works
Evaluation of between-methods agreement of extracellular water measurements in adults and children
Silva, A. M., Heymsfield, S. B., Gallagher, D., Albu, J., Pi-Sunyer, X. F., Pierson, R. N., Wang, J., Heshka, S., Sardinha, L. B., & Wang, Z. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/88.2.315 · Cited by 31 · see citing works
Cytochalasin D induces edema formation and lowering of interstitial fluid pressure in rat dermis
Berg, A., Rubin, K., & Reed, R. K. (2001) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2001.281.1.h7 · Cited by 30 · see citing works
A study on oedema mechanism in nephrotic syndrome
FADNES, H. O., Pape, J. F., & Sundsfjord, J. (1986) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365518609083709 · Cited by 30 · see citing works
Progress toward resolving the controversy of positive Vs. negative interstitial fluid pressure.
Brace, R. A. (1981) · Circulation Research · doi:10.1161/01.res.49.2.281 · Cited by 29 · see citing works
Are large amounts of sodium stored in an osmotically inactive form during sodium retention? Balance studies in freely moving dogs
Seeliger, E., Wiegard, M., & Reinhardt, H. W. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00676.2005 · Cited by 29 · see citing works
Body fluid abnormalities in severe hyperglycemia in patients on chronic dialysis: theoretical analysis
Tzamaloukas, A. H., Ing, T. S., Siamopoulos, K. C., Rohrscheib, M. R., Elisaf, M., Raj, D. S., & Murata, G. H. (2007) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2007.05.007 · Cited by 29 · see citing works
Hypovolemia and hypovolemic shock in children with nephrotic syndrome.
Wang, S., Tsau, Y., Lu, F. L., & Chen, C. H. (2000) · PubMed · Cited by 28 · see citing works
Urea gradient-associated fluid absorption with sigma urea = 1 in rat terminal collecting duct
Chou, C., Sands, J. M., Nonoguchi, H., & Knepper, M. A. (1990) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.1990.258.5.f1173 · Cited by 28 · see citing works
THE OSMOTIC BEHAVIOUR OF THE BODY CELLS IN MAN
Wynn, V. (1957) · The Lancet · doi:10.1016/s0140-6736(57)90177-0 · Cited by 27 · see citing works
Pathophysiology of oedema in idiopathic nephrotic syndrome
Koomans, H. A. (2003) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfg1063 · Cited by 27 · see citing works
Concurrent Estimation of Total Body and Exchangeable Body Sodium in Hypertension
Boddy, K., Brown, J. J., Davies, D. L., Elliott, A. T., Harvey, I., Haywood, J. K., Holloway, I., Lever, A. F., Robertson, J. I. S., & Williams, E. D. (1978) · Clinical Science · doi:10.1042/cs0540187 · Cited by 27 · see citing works
Human platelet osmotic water and nonelectrolyte transport
Meyer, M. M., & Verkman, A. S. (1986) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1986.251.4.c549 · Cited by 26 · see citing works
Are extracellular osmolality and sodium concentration determined by Donnan effects of intracellular protein charges and of pumped sodium?
Kurbel, S. (2008) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2008.02.022 · Cited by 25 · see citing works
Body sodium and potassium. II. A comparison of metabolic balance and isotope dilution methods of study.
Gm, W., Olney, J. M., Brooks, L., Ja, M., Mr, B., & Fd, M. (1954) · PubMed · Cited by 23 · see citing works
Total body sodium by whole body neutron activation in the living subject: further evidence for non-exchangeable sodium pool.
Chamberlain, M. J., Fremlin, J. H., Peters, D. K., & Philip, H. (1968) · BMJ · doi:10.1136/bmj.2.5605.583 · Cited by 22 · see citing works
Interstitial exclusion of macromolecules studied by graded centrifugation of rat tail tendon
Aukland, K., Wiig, H., Tenstad, O., & Renkin, E. M. (1997) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1997.273.6.h2794 · Cited by 21 · see citing works
Water movement: does thermodynamic interpretation distort reality?
Essig, A., & Caplan, S. R. (1989) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1989.256.3.c694 · Cited by 20 · see citing works
Urea Transport: It’s Not Just “Freely Diffusible” Anymore
Sands, J. M. (1999) · Physiology · doi:10.1152/physiologyonline.1999.14.1.46 · Cited by 17 · see citing works
Control of blood volume
Manning, R. D., & Guyton, A. C. (1982) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/bfb0032669 · Cited by 14 · see citing works
Colloid Osmotic Pressures of Serum Proteins in Nephrosis and Cirrhosis: Relations to Electrophoretic Distributions and Average Molecular Weights
Armstrong, S. H., Kark, R. M., Schoenberger, J. A., Shatkin, J., & Sights, R. (1954) · Journal of Clinical Investigation · doi:10.1172/jci102898 · Cited by 14 · see citing works
Subcutaneous interstitial fluid colloid osmotic pressure in dehydrated rats
Heir, S., & Wiig, H. (1988) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1988.tb08418.x · Cited by 14 · see citing works
Studies on sodium in bone
Forbes, G. B. (1960) · The Journal of Pediatrics · doi:10.1016/s0022-3476(60)80118-7 · Cited by 13 · see citing works
Equation for osmotic pressure of serum protein (fractions)
Ahlqvist, J. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00880.2003 · Cited by 13 · see citing works
Determination of Inulin, Albumin and Erythrocyte Spaces in the Bone Marrow of Rabbits
Michelsen, K. (1969) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1969.tb04550.x · Cited by 13 · see citing works
Observations on sodium balance in patients undergoing mitral valvotomy.
Deming, Q. B., & Gerbode, F. L. A. (1953) · PubMed · Cited by 12 · see citing works
Syndrome of inappropriate vasopressin secretion. Studies on the mechanism of the hyponatremia in a patient
Clift, G. V. (1966) · Archives of Internal Medicine · doi:10.1001/archinte.118.5.453 · Cited by 12 · see citing works
Syndrome of Inappropriate Vasopressin Secretion
Clift, G. V. (1966) · Archives of Internal Medicine · doi:10.1001/archinte.1966.00290170041008 · Cited by 11 · see citing works
Is the osmotically inactive sodium storage pool fixed or variable?
Nguyen, M. K., & Kurtz, I. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00614.2006 · Cited by 10 · see citing works
Swelling and pressure-volume relationships in the dermis measured by osmotic-stress technique
McGee, M. P., Morykwas, M. J., Levi‐Polyachenko, N. H., & Argenta, L. C. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90777.2008 · Cited by 10 · see citing works
Effect of Large Loads of Sodium on Bone and Soft Tissue Composition.
Nichols, N., & Nichols, G. (1957) · Experimental Biology and Medicine · doi:10.3181/00379727-96-23624 · Cited by 10 · see citing works
Abdominal Pain and Vomiting in a Boy With Nephrotic Syndrome
Theuns-Valks, S. D. M., van Wijk, J. A. E., van Heerde, M., Dolman, K. M., & Bökenkamp, A. (2010) · Clinical Pediatrics · doi:10.1177/0009922810361366 · Cited by 5 · see citing works
Protein osmotic pressure gradients and microvascular reflection coefficients
Drake, R. E., Dhother, S., Teague, R. A., & Gabel, J. (1997) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1997.273.2.h997 · Cited by 4 · see citing works
The use of linear nonequilibrium thermodynamics in the study of renal physiology
Essig, A., & Caplan, S. R. (1979) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.1979.236.3.f211 · Cited by 3 · see citing works
The response to water-salt loading: sodium metabolism in spontaneously hypertensive rats.
Ln, I., Nn, M., Vm, M., Ls, S., & Vf, Z. (1987) · PubMed · Cited by 1 · see citing works
The balancing act of the naked cell: a brief history of membrane regulation of animal cell volume before 1978.
Willis, J. S. (2004) · PubMed · Cited by 1 · see citing works
[Kinetics of tissue sodium metabolism and the vascular reactivity to vasopressor agents in healthy persons with different degree of risk of developing arterial hypertension].
Vm, M., & Shterental, I. S. (1988) · PubMed · Cited by 1 · see citing works
[Distribution of sodium in the tissues in experimental salt hypertension].
Vf, Z., Te, P., Vk, A., & Is, S. (1975) · PubMed · Cited by 1 · see citing works

Flagged first, then by citations

4 of the 192 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

[17]International Commission on Radiological Protection Task Group on Reference Man. Report of the Task Group on Reference Man: a report 1975 Pergamon Press Oxford; New York
[25]Robinson RA RODAHL K NICHOLSON JT BROWN EM Chemical Analysis and Electron Microscopy of Bone. Bone as a Tissue. Lankenau Hospital 1960 186 251 McGraw-Hill Philadelphia

Sorted by citations

Clinical practice guideline on diagnosis and treatment of hyponatraemia
Spasovski, G. B., Vanholder, R. C., Allolio, B., Annane, D., Ball, S., Bichet, D. G., Decaux, G., Fenske, W., Hoorn, E. J., Ichaï, C., et al. (2014) · Intensive Care Medicine · doi:10.1007/s00134-014-3210-2 · Cited by 1,020 · see citing works
Clinical practice guideline on diagnosis and treatment of hyponatraemia
Spasovski, G. B., Vanholder, R. C., Allolio, B., Annane, D., Ball, S., Bichet, D. G., Decaux, G., Fenske, W. K., Hoorn, E. J., Ichaï, C., et al. (2014) · European Journal of Endocrinology · doi:10.1530/eje-13-1020 · Cited by 862 · see citing works
Disorders of Plasma Sodium — Causes, Consequences, and Correction
Sterns, R. H. (2014) · New England Journal of Medicine · doi:10.1056/nejmra1404489 · Cited by 630 · see citing works
Clinical practice guideline on diagnosis and treatment of hyponatraemia
Spasovski, G. B., Vanholder, R. C., Allolio, B., Annane, D., Ball, S., Bichet, D. G., Decaux, G., Fenske, W. K., Hoorn, E. J., Ichaï, C., et al. (2014) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfu040 · Cited by 577 · see citing works
The Role of Water Homeostasis in Muscle Function and Frailty: A Review
Lorenzo, I., Serra-Prat, M., & Yébenes, J. C. (2019) · Nutrients · doi:10.3390/nu11081857 · Cited by 239 · see citing works
Physical Chemistry of Nanomedicine: Understanding the Complex Behaviors of Nanoparticles in Vivo
Lane, L. A., Qian, X., Smith, A. M., & Nie, S. (2015) · Annual Review of Physical Chemistry · doi:10.1146/annurev-physchem-040513-103718 · Cited by 176 · see citing works
The role of the kidney in regulating arterial blood pressure
Wadei, H. M., & Textor, S. C. (2012) · Nature Reviews Nephrology · doi:10.1038/nrneph.2012.191 · Cited by 167 · see citing works
The Challenge of Hyponatremia
Adrogué, H. J., & Madias, N. E. (2012) · Journal of the American Society of Nephrology · doi:10.1681/asn.2012020128 · Cited by 167 · see citing works
Biosensing in dermal interstitial fluid using microneedle based electrochemical devices
Madden, J., O’Mahony, C., Thompson, M. E., O'Riordan, A. J., & Galvin, P. (2020) · Sensing and Bio-Sensing Research · doi:10.1016/j.sbsr.2020.100348 · Cited by 161 · see citing works
Diagnosis and treatment of hypernatremia
Muhsin, S. A., & Mount, D. B. (2016) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2016.02.014 · Cited by 143 · see citing works
The interstitium conducts extrarenal storage of sodium and represents a third compartment essential for extracellular volume and blood pressure homeostasis
Wiig, H., Luft, F. C., & Titze, J. M. (2017) · Acta Physiologica · doi:10.1111/apha.13006 · Cited by 144 · see citing works
Protein glycation – biomarkers of metabolic dysfunction and early-stage decline in health in the era of precision medicine
Rabbani, N., & Thornalley, P. J. (2021) · Redox Biology · doi:10.1016/j.redox.2021.101920 · Cited by 118 · see citing works
Insights into Salt Handling and Blood Pressure
Ellison, D. H., & Welling, P. (2021) · New England Journal of Medicine · doi:10.1056/nejmra2030212 · Cited by 113 · see citing works
Capillary leak and endothelial permeability in critically ill patients: a current overview
Saravi, B., Goebel, U., Hassenzahl, L. O., Jung, C., David, S., Feldheiser, A., Stopfkuchen-Evans, M. F., & Wollborn, J. (2023) · Intensive Care Medicine Experimental · doi:10.1186/s40635-023-00582-8 · Cited by 100 · see citing works
Ketogenic diet as a potential intervention for lipedema
Keith, L., Seo, C. A., Rowsemitt, C. N., Pfeffer, M., Wahi, M. M., Staggs, M., Dudek, J. E., Gower, B. A., & Carmody, M. (2020) · Medical Hypotheses · doi:10.1016/j.mehy.2020.110435 · Cited by 97 · see citing works
Thiazide-Associated Hyponatremia: Clinical Manifestations and Pathophysiology
Filippone, E. J., Ruzieh, M., & Foy, A. (2019) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2019.07.011 · Cited by 95 · see citing works
Tissue sodium excess is not hypertonic and reflects extracellular volume expansion
Rossitto, G., Mary, S., Chen, J. Y., Boder, P., Chew, K. S., Neves, K. B., Alves, R. L., Montezano, A. C., Welsh, P., Petrie, M. C., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-17820-2 · Cited by 94 · see citing works
International society of sports nutrition position stand: nutritional concerns of the female athlete
Sims, S. T., Kerksick, C. M., Smith-Ryan, A. E., Janse de Jonge, X. A. K., Hirsch, K. R., Arent, S. M., Hewlings, S. J., Kleiner, S. M., Bustillo, E., Tartar, J. L., et al. (2023) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2023.2204066 · Cited by 91 · see citing works
“tion with a lower proportion of total body water [274] distributed to the extracellular compartment, as compared to males, females have less absolute and relative fluid available to lose via sweating making the physiological consequences of fluid loss more severe [45].”
Background
A different view on sodium balance
Titze, J. M. (2014) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0000000000000085 · Cited by 82 · see citing works
Fluid Overload
Hansen, B. D. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.668688 · Cited by 76 · see citing works
Dicarbonyl stress in clinical obesity
Masania, J., Malczewska-Malec, M., Raźny, U., Góralska, J., Zdzienicka, A., Kieć‐Wilk, B., Gruca, A., Stancel-Możwiłło, J., Dembinska-Kiec, A., Rabbani, N., et al. (2016) · Glycoconjugate Journal · doi:10.1007/s10719-016-9692-0 · Cited by 76 · see citing works
Sodium and water handling during hemodialysis: new pathophysiologic insights and management approaches for improving outcomes in end-stage kidney disease.
Canaud, B., Kooman, J., Selby, N., Taal, M., Francis, S., Kopperschmidt, P., Maierhofer, A., Kotanko, P., & Titze, J. (2019) · Kidney International · doi:10.1016/j.kint.2018.09.024 · Cited by 58 · see citing works
Hypovolemia with peripheral edema: What is wrong?
Dull, R. O., & Hahn, R. G. (2023) · Critical Care · doi:10.1186/s13054-023-04496-5 · Cited by 61 · see citing works
ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysis
Brossier, D., Tume, L. N., Briant, A. R., Chaparro, C. J., Moullet, C., Rooze, S., Verbruggen, S. C. A. T., Marino, L. V., Alsohime, F., Beldjilali, S., et al. (2022) · Intensive Care Medicine · doi:10.1007/s00134-022-06882-z · Cited by 61 · see citing works
Association of Predialysis Calculated Plasma Osmolarity With Intradialytic Blood Pressure Decline
Causland, F. R. M., & Waikar, S. S. (2015) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2015.03.028 · Cited by 53 · see citing works
Skin Sodium and Hypertension: a Paradigm Shift?
Selvarajah, V., Connolly, K., McEniery, C. M., & Wilkinson, I. B. (2018) · Current Hypertension Reports · doi:10.1007/s11906-018-0892-9 · Cited by 54 · see citing works
Sodium surfeit and potassium deficit: Keys to the pathogenesis of hypertension
Adrogué, H. J., & Madias, N. E. (2013) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2013.09.003 · Cited by 49 · see citing works
Optical-Based Biosensors and Their Portable Healthcare Devices for Detecting and Monitoring Biomarkers in Body Fluids
Pham, A. T. T., Wallace, A. K., Zhang, X., Tohl, D., Fu, H., Chuah, C., Reynolds, K. J., Ramsey, C., & Tang, Y. (2021) · Diagnostics · doi:10.3390/diagnostics11071285 · Cited by 45 · see citing works
The role of albumin and the extracellular matrix on the pathophysiology of oedema formation in severe malnutrition
Gonzales, G. B., Njunge, J. M., Gichuki, B. M., Wen, B., Ngari, M. M., Potani, I., Thitiri, J., Laukens, D., Voskuijl, W. P., Bandsma, R., et al. (2022) · EBioMedicine · doi:10.1016/j.ebiom.2022.103991 · Cited by 45 · see citing works
Effect of gamma sterilization on the properties of microneedle array transdermal patch system
Swathi, H. P., Matadh, A. V., Guin, J. P., Murthy, S. N., Kanni, P., Varshney, L., Suresh, S., & Shivakumar, H. N. (2020) · Drug Development and Industrial Pharmacy · doi:10.1080/03639045.2020.1742144 · Cited by 45 · see citing works
Pseudohypernatremia and pseudohyponatremia: a linear correction
Goldwasser, P., Ayoub, I. M., & Barth, R. H. (2014) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfu298 · Cited by 45 · see citing works
Serum osmolality and hyperosmolar states
Büyükkaragöz, B., & Bakkaloglu, S. A. (2022) · Pediatric Nephrology · doi:10.1007/s00467-022-05668-1 · Cited by 42 · see citing works
Chloride in Heart Failure Syndrome: Its Pathophysiologic Role and Therapeutic Implication
Kataoka, H. (2021) · Cardiology and Therapy · doi:10.1007/s40119-021-00238-2 · Cited by 40 · see citing works
Tear Osmolarity in the Diagnosis of Systemic Dehydration and Dry Eye Disease
Bron, A. J., & Willshire, C. (2021) · Diagnostics · doi:10.3390/diagnostics11030387 · Cited by 35 · see citing works
The Corrected Serum Sodium Concentration in Hyperglycemic Crises: Computation and Clinical Applications
Ing, T. S., Ganta, K., Bhave, G. B., Lew, S. Q., Agaba, E. I., Argyropoulos, C., & Tzamaloukas, A. H. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.00477 · Cited by 33 · see citing works
Self-citation
Whole body acid-base and fluid-electrolyte balance: a mathematical model
Wolf, M. B. (2013) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00195.2013 · Cited by 31 · see citing works
Applications of Manganese-Enhanced Magnetic Resonance Imaging in Ophthalmology and Visual Neuroscience
Deng, W., Faiq, M. A., Liu, C., Adi, V., & Chan, K. C. (2019) · Frontiers in Neural Circuits · doi:10.3389/fncir.2019.00035 · Cited by 30 · see citing works
Advances in the Starling Principle and Microvascular Fluid Exchange; Consequences and Implications for Fluid Therapy
Woodcock, T. E., & Michel, C. C. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.623671 · Cited by 30 · see citing works
Transdermal amperometric biosensors for continuous glucose monitoring in diabetes
Liu, Y., Li, Y., & Cui, Y. (2022) · Talanta · doi:10.1016/j.talanta.2022.124033 · Cited by 29 · see citing works
Higher ratio of extracellular water to total body water was associated with reduced cognitive function in type 2 diabetes
Low, S. K., Ng, T. P., Lim, C. L., Ang, S. F., Moh, A. M. C., Wang, J., Yap, P. L. K., Cheong, C. Y., Goh, K. S., Ang, K., et al. (2020) · Journal of Diabetes · doi:10.1111/1753-0407.13104 · Cited by 29 · see citing works
Fluid type influences acute hydration and muscle performance recovery in human subjects
Harris, P. R., Keen, D. A., Constantopoulos, E., Weninger, S. N., Hines, E. R., Koppinger, M. P., Khalpey, Z. I., & Konhilas, J. P. (2019) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-019-0282-y · Cited by 28 · see citing works
The ebb and flow of cardiac lymphatics: a tidal wave of new discoveries
Harris, N. R., Bálint, L., Dy, D., Nielsen, N. R., Méndez, H. G., Aghajanian, A., & Caron, K. M. (2022) · Physiological Reviews · doi:10.1152/physrev.00052.2021 · Cited by 27 · see citing works
Fitness Cost of Rifampin Resistance in Neisseria meningitidis: In Vitro Study of Mechanisms Associated with rpoB H553Y Mutation
Colicchio, R., Pagliuca, C., Pastore, G., Cicatiello, A. G., Pagliarulo, C., Talà, A., Scaglione, E., Sammartino, J. C., Bucci, C., Alifano, P., et al. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01746-15 · Cited by 26 · see citing works
Enhancement of the serum chloride concentration by administration of sodium–glucose cotransporter-2 inhibitor and its mechanisms and clinical significance in type 2 diabetic patients: a pilot study
Kataoka, H., & Yoshida, Y. (2020) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-020-0515-x · Cited by 26 · see citing works
Time course of the Bioelectrical Impedance Vector Analysis and muscular ultrasound in critically ill patients
Formenti, P., Coppola, S., Umbrello, M., Froio, S., Caccioppola, A., Giorgis, V. D., Galanti, V., Lusardi, A. C., Ferrari, E., Noè, D., et al. (2021) · Journal of Critical Care · doi:10.1016/j.jcrc.2021.11.014 · Cited by 26 · see citing works
Which fluid space is affected by ultrafiltration during hemodiafiltration?
Tapolyai, M., Faludi, M., Fülöp, T., Dossabhoy, N., Szombathelyi, A., & Berta, K. (2014) · Hemodialysis international. International Symposium on Home Hemodialysis · doi:10.1111/hdi.12125 · Cited by 26 · see citing works
Outcomes and predictors of skin sodium concentration in dialysis patients
Salerno, F. R., Akbari, A., Lemoine, S., Filler, G., Scholl, T. J., & McIntyre, C. W. (2022) · Clinical Kidney Journal · doi:10.1093/ckj/sfac021 · Cited by 25 · see citing works
Using Electrolyte Free Water Balance to Rationalize and Treat Dysnatremias
Shah, S. R., & Bhave, G. B. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2018.00103 · Cited by 23 · see citing works
Self-citation
Body Fluids in End-Stage Renal Disease: Statics and Dynamics
Kooman, J. P., & SANDE, F. M. V. D. (2018) · Blood Purification · doi:10.1159/000494583 · Cited by 22 · see citing works
In silico model of the dilutional effects of conventional component therapy versus whole blood in the management of massively bleeding adult trauma patients
Seheult, J. N., Stram, M. N., Sperry, J. L., Spinella, P. C., Triulzi, D. J., & Yazer, M. H. (2018) · Transfusion · doi:10.1111/trf.14983 · Cited by 22 · see citing works
Genetic Engineering of Lymphangiogenesis in Skin Does Not Affect Blood Pressure in Mouse Models of Salt-Sensitive Hypertension
Thowsen, I., Reikvam, T., Skogstrand, T., Samuelsson, A., Müller, D. N., Tenstad, O., Alitalo, K. K., Karlsen, T. V., & Wiig, H. (2022) · Hypertension · doi:10.1161/hypertensionaha.122.19777 · Cited by 22 · see citing works
Recent advances in the understanding of endothelial barrier function and fluid therapy
Thind, G. S., Zanders, S., & Baker, J. K. (2018) · Postgraduate Medical Journal · doi:10.1136/postgradmedj-2017-135125 · Cited by 20 · see citing works
Variability in Retinal Neuron Populations and Associated Variations in Mass Transport Systems of the Retina in Health and Aging
Zouache, M. A. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.778404 · Cited by 19 · see citing works
The interstitial compartment as a therapeutic target in heart failure
Aronson, D. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.933384 · Cited by 19 · see citing works
Skin Sodium and Blood Pressure Regulation
Jhee, J. H., Park, H. C., & Choi, H. Y. (2022) · Electrolytes & Blood Pressure · doi:10.5049/ebp.2022.20.1.1 · Cited by 19 · see citing works
Tangram of Sodium and Fluid Balance
Bagordo, D., Rossi, G. P., Delles, C., Wiig, H., & Rossitto, G. (2023) · Hypertension · doi:10.1161/hypertensionaha.123.19569 · Cited by 22 · see citing works
Quantification of lung water density with UTE Yarnball MRI
Meadus, W. Q., Stobbe, R., Grenier, J. G., Beaulieu, C., & Thompson, R. B. (2021) · Magnetic Resonance in Medicine · doi:10.1002/mrm.28800 · Cited by 18 · see citing works
Much Ado about N…atrium: modelling tissue sodium as a highly sensitive marker of subclinical and localized oedema
Rossitto, G., Touyz, R. M., Petrie, M. C., & Delles, C. (2018) · Clinical Science · doi:10.1042/cs20180575 · Cited by 18 · see citing works
TRAP1 inhibits MIC60 ubiquitination to mitigate the injury of cardiomyocytes and protect mitochondria in extracellular acidosis
Zhang, L., Su, N., Luo, Y., Chen, S., & Zhao, T. (2021) · Cell Death Discovery · doi:10.1038/s41420-021-00786-5 · Cited by 17 · see citing works
Perioperative fluid therapy and intraoperative blood loss in children
Bhardwaj, N. (2019) · Indian Journal of Anaesthesia · doi:10.4103/ija.ija_493_19 · Cited by 17 · see citing works
Oxygen Consumption In Vivo by Ultra-High Dose Rate Electron Irradiation Depends Upon Baseline Tissue Oxygenation
Sunnerberg, J. P., Tavakkoli, A. D., Pétusseau, A. F., Daniel, N. J., Sloop, A. M., Schreiber, W. A., Gui, J., Zhang, R., Swartz, H. M., Hoopes, P. J., et al. (2024) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2024.10.018 · Cited by 16 · see citing works
Risks of severe hyponatremia in children receiving hypotonic fluids
Mercier, J., Titomanlio, L., Basmaci, R., & Gaschignard, J. (2020) · Archives de Pédiatrie · doi:10.1016/j.arcped.2020.08.009 · Cited by 15 · see citing works
Understanding Volume Kinetics: The Role of Pharmacokinetic Modeling and Analysis in Fluid Therapy
Yiew, X. T., Bateman, S. W., Hahn, R. G., Bersenas, A. M. E., & Muir, W. W. (2020) · Frontiers in Veterinary Science · doi:10.3389/fvets.2020.587106 · Cited by 16 · see citing works
Total Body Sodium Balance in Chronic Kidney Disease
Martin, K., Tan, S., & Toussaint, N. D. (2021) · International Journal of Nephrology · doi:10.1155/2021/7562357 · Cited by 15 · see citing works
Radioisotope blood volume measurement in hemodialysis patients
Puri, S., Park, J.-K., Modersitzki, F., & Goldfarb, D. S. (2014) · Hemodialysis international. International Symposium on Home Hemodialysis · doi:10.1111/hdi.12105 · Cited by 14 · see citing works
Use of Dimensional Analysis in the X-, Y-, and Z-Axis to Predict Occurrence of Injury in Human Stampede
Alhadhira, A. A., Molloy, M. J., Casasola, M., Sarin, R. R., Massey, M. S., Voskanyan, A., & Ciottone, G. R. (2019) · Disaster Medicine and Public Health Preparedness · doi:10.1017/dmp.2019.47 · Cited by 14 · see citing works
Editorial: Fluid Therapy in Animals: Physiologic Principles and Contemporary Fluid Resuscitation Considerations
Muir, W. W., Hughes, D., & Silverstein, D. C. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.744080 · Cited by 14 · see citing works
Proposal for New Classification and Practical Use of Diuretics According to Their Effects on the Serum Chloride Concentration: Rationale Based on the “Chloride Theory”
Kataoka, H. (2020) · Cardiology and Therapy · doi:10.1007/s40119-020-00172-9 · Cited by 12 · see citing works
Dosing Common Medications in Hospitalized Pediatric Patients with Obesity: A Review
Ameer, B., & Weintraub, M. A. (2020) · Obesity · doi:10.1002/oby.22739 · Cited by 12 · see citing works
A Slow-Exchange Interstitial Fluid Compartment in Volunteers and Anesthetized Patients: Kinetic Analysis and Physiology
Hahn, R. G., & Dull, R. O. (2023) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000006767 · Cited by 12 · see citing works
Evolution of Bioelectric Membrane Potentials: Implications in Cancer Pathogenesis and Therapeutic Strategies
Shrivastava, A., Kumar, A., Aggarwal, L. M., Pradhan, S., Choudhary, S., Ashish, A., Kashyap, K., & Mishra, S. B. (2024) · The Journal of Membrane Biology · doi:10.1007/s00232-024-00323-2 · Cited by 12 · see citing works
Effects of pediatric chronic kidney disease and its etiology on tissue sodium concentration: a pilot study
Salerno, F. R., Akbari, A., Lemoine, S., Scholl, T. J., McIntyre, C. W., & Filler, G. (2022) · Pediatric Nephrology · doi:10.1007/s00467-022-05600-7 · Cited by 12 · see citing works
Impact of water consumption on renal function in the general population: a cross-sectional analysis of KNHANES data (2008–2017)
Lo, J.-A., Kim, J. S., Jo, M. J., Cho, E. J., Ahn, S. Y., Ko, G. J., Kwon, Y. J., & Kim, J. E. (2021) · Clinical and Experimental Nephrology · doi:10.1007/s10157-020-01997-3 · Cited by 13 · see citing works
Dissociable effects of dietary sodium in early life upon somatic growth, fluid homeostasis, and spatial memory in mice of both sexes
Segar, J. L., Grobe, C. C., Balapattabi, K., Ritter, M. L., Reho, J. J., & Grobe, J. L. (2021) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00281.2020 · Cited by 12 · see citing works
Mechanoadaptive Bioelectronics for Deep Tissue Sensing
Ren, X., Yuan, Y., Li, J., & Hu, B. (2024) · Chinese Journal of Chemistry · doi:10.1002/cjoc.202400879 · Cited by 11 · see citing works
A personalized model and optimization strategy for estimating blood glucose concentrations from sweat measurements
Yin, X., Peri, E., Pelssers, E., den Toonder, J. M. J., Klous, L., Daanen, H. A. M., & Mischi, M. (2025) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2025.108743 · Cited by 11 · see citing works
Peak Week Carbohydrate Manipulation Practices in Physique Athletes: A Narrative Review
Homer, K. A., Cross, M. R., & Helms, E. R. (2024) · Sports Medicine - Open · doi:10.1186/s40798-024-00674-z · Cited by 12 · see citing works
Magnetic resonance imaging determination of tissue sodium in patients with chronic kidney disease
Martin, K., Tan, S., & Toussaint, N. D. (2021) · Nephrology · doi:10.1111/nep.13975 · Cited by 11 · see citing works
Skin regulation of salt and blood pressure and potential clinical implications
Martin, K., Toussaint, N. D., Tan, S., & Hewitson, T. D. (2022) · Hypertension Research · doi:10.1038/s41440-022-01096-8 · Cited by 11 · see citing works
Acupuncture in Modern Medicine
Chen, L. L., & Cheng, T. O. (2013) · InTech eBooks · doi:10.5772/46017 · Cited by 10 · see citing works
Biochemical Indices of Drug Toxicity
Ofori, E. K. (2022) · Springer eBooks · doi:10.1007/978-3-031-12398-6_20 · Cited by 9 · see citing works
Intestinal interstitial fluid isolation provides novel insight into the human host-microbiome interface
Avery, E. G., Haag, L.-M., McParland, V. J., Kedziora, S. M., Zigra, G., Valdes, D. S., Kirchner, M., Popp, O., Geisberger, S., Nonn, O., et al. (2025) · Cardiovascular Research · doi:10.1093/cvr/cvae267 · Cited by 8 · see citing works
Influences of sodium and glycosaminoglycans on skin oedema and the potential for ulceration: a finite-element approach
Pan, W., Roccabianca, S., Basson, M. D., & Bush, T. R. (2019) · Royal Society Open Science · doi:10.1098/rsos.182076 · Cited by 8 · see citing works
Terms, Definitions, Nomenclature, and Routes of Fluid Administration
Chow, R. S. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2020.591218 · Cited by 9 · see citing works
Animal, Human, and 23Na MRI Imaging Evidence for the Negative Impact of High Dietary Salt in Children
Filler, G., Salerno, F. R., McIntyre, C. W., & Ferris, M. (2021) · Current Pediatrics Reports · doi:10.1007/s40124-021-00249-6 · Cited by 8 · see citing works
The Ins and Outs of IV Fluids in Hemodynamic Resuscitation
Kaufman, D. A., Lopes, M. A., Malviya, N., & Magder, S. A. (2023) · Critical Care Medicine · doi:10.1097/ccm.0000000000006001 · Cited by 7 · see citing works
Dynamic changes in lung water density and volume following supine body positioning
Goodhart, T., Seres, P., Grenier, J. G., Keen, C., Stobbe, R., & Thompson, R. B. (2024) · Magnetic Resonance in Medicine · doi:10.1002/mrm.30017 · Cited by 7 · see citing works
Plausible Biomedical Consequences of Acupuncture Applied at Sites Characteristic of Acupoints in the Connective-Tissue-Interstitial-Fluid System
Fung, P. C. W. (2013) · InTech eBooks · doi:10.5772/53901 · Cited by 7 · see citing works
Detection of Hyponatremia Development in Hemodialysis Patients by Routine Automated Conductivity-Based Monitoring
Maierhofer, A. P., Harlos, J., & Canaud, B. (2022) · ASAIO Journal · doi:10.1097/mat.0000000000001737 · Cited by 7 · see citing works
Feasibility of Skin Water Content Imaging Using CMOS Sensors
Saiko, G. (2023) · Sensors · doi:10.3390/s23020919 · Cited by 7 · see citing works
Fluid and Electrolyte Balance
Unny, N. M., Zarina, A., & Beena, V. (2023) · Springer eBooks · doi:10.1007/978-981-19-9410-4_8 · Cited by 7 · see citing works
Plasma Leak From the Circulation Contributes to Poor Outcomes for Preterm Infants: A Working Hypothesis
Eiby, Y. A., Lingwood, B. E., & Wright, I. M. R. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.636740 · Cited by 7 · see citing works
Regulation of Fluid Volume From the Outside
Wiig, H. (2018) · Circulation Heart Failure · doi:10.1161/circheartfailure.118.005135 · Cited by 7 · see citing works
Continuous monitoring of blood–interstitial fluid intercompartmental molecular kinetics in freely moving animals
Chen, Y., Hu, Q., Kwak, J. W., Zakharian, D., Ji, J., Liu, D., Gopalan, D., Lyons, C., Yates, M., Yee, S. C., et al. (2026) · Science Advances · doi:10.1126/sciadv.aed1895 · Cited by 6 · see citing works
The Story of Aldosterone Escape
Prasad, D., Drysch, A. P., Upadhyay, D., & Neilson, E. G. (2025) · Journal of the American Society of Nephrology · doi:10.1681/asn.0000000908 · Cited by 5 · see citing works
Self-citation
Blood volume analysis as a guide for dry weight determination in chronic hemodialysis patients: a crossover study
Malha, L., Fattah, H., Modersitzki, F., & Goldfarb, D. (2019) · BMC Nephrology · doi:10.1186/s12882-019-1211-7 · Cited by 4 · see citing works
Effects of hemodialysis on blood volume, macro- and microvascular function
Montero, D., Haider, T., Nägele, M. P., Barthelmes, J., Cantatore, S., Sudano, I., Ruschitzka, F. T., Bonani, M., & Flammer, A. J. (2019) · Microvascular Research · doi:10.1016/j.mvr.2019.103958 · Cited by 5 · see citing works
Effusion-Serum Chloride Gradient in Heart Failure-Associated Pleural Effusion ― Pathophysiologic Implications ―
Kataoka, H. (2020) · Circulation Reports · doi:10.1253/circrep.cr-20-0018 · Cited by 5 · see citing works
Severe hyponatremia in children: a review of the literature through instructive cases
MAZZOLAI, M., APICELLA, A., MARZUILLO, P., RABACH, I., Taddio, A., BARBI, E., & COZZI, G. (2022) · Minerva Pediatrics · doi:10.23736/s2724-5276.21.05856-4 · Cited by 5 · see citing works
Culture in embryonic kidney serum and xeno-free media as renal cell carcinoma and renal cell carcinoma cancer stem cells research model
Krawczyk, K. M., Matak, D., Szymański, Ł., Szczylik, C. A., Porta, C., & Czarnecka, A. M. (2018) · Cytotechnology · doi:10.1007/s10616-017-0181-5 · Cited by 5 · see citing works

Authors: Bhave, G., & Neilson, E. G.
Affiliations: Vanderbilt University (US)
Northwestern University (US)
Corresponding author: Bhave, Gautam
Neilson, Eric G.
ORCID: Bhave, Gautam
Neilson, Eric G.
Venue: Journal of the American Society of Nephrology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2011-12
Volume: 22
Issue: 12
Pages: 2166-2181
ISSN: 1046-6673 (ISSN-L)
DOI: 10.1681/asn.2011080865
PMC: PMC4096826
OpenAlex: W2152290339
Cited by: 215
References: 192
Citations by year: 2026: 9 · 2025: 15 · 2024: 49 · 2023: 15 · 2022: 21 · 2021: 27 · 2020: 18 · 2019: 18 · 2018: 13 · 2017: 3 · 2016: 4 · 2015: 6 · 2014: 8 · 2013: 6 · 2012: 2
FWCI: 0.49
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Journal of the American Society of Nephrology (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Diabetes and Digestive and Kidney Diseases (T32DK007569)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion Transport and Channel Regulation
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Electrolyte and hormonal disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Chemical and Physical Studies
Keywords: interstitial space, transcapillary fluid exchange, tonicity, capillary permeability, interstitial fluid
MeSH terms: Animals, Body Fluids, Forecasting, Humans, Hydrodynamics

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Body Fluid Dynamics: Back to the Future

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks