Cited by 3,125Heart Failure Treatment and ManagementElectrolyte and hormonal disordersCardiac Fibrosis and Remodeling

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Plasma Norepinephrine as a Guide to Prognosis in Patients with Chronic Congestive Heart Failure

Cohn, Jay N., Levine, T. Barry, Olivari, Maria Teresa, Garberg, Victoria, Lura, Dennis, Francis, Gary S., Simon, Ada B., Rector, Thomas·1984·New England Journal of Medicine

DOI 10.1056/nejm198409273111303

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Abstract

Hemodynamics, plasma norepinephrine, and plasma renin activity were measured at supine rest in 106 patients (83 men and 23 women) with moderate to severe congestive heart failure. During follow-up lasting 1 to 62 months, 60 patients died (57 per cent); 47 per cent of the deaths were sudden, and 45 per cent were related to progressive heart failure. Statistically unrelated to the risk of mortality were cause of disease (60 patients had coronary disease, and 46 had cardiomyopathy), age (mean, 54.8 years), cardiac index (mean, 2.11 liters per minute per square meter of body-surface area), pulmonary wedge pressure (mean, 24.5 mm Hg), and mean arterial pressure (mean, 83.2 mm Hg). A multivariate analysis of the five significant univariate prognosticators--heart rate (mean, 84.4 beats per minute), plasma renin activity (mean, 15.4 ng per milliliter per hour), plasma norepinephrine (mean, 700 pg per milliliter), serum sodium (mean, 135.7 mmol per liter), and stroke-work index (mean, 21.0 g-meters per square meter)--found only plasma norepinephrine to be independently (P = 0.002) related to the subsequent risk of mortality. Norepinephrine was also higher in patients who died from progressive heart failure than in those who died suddenly. These data suggest that a single resting venous blood sample showing the plasma norepinephrine concentration provides a better guide to prognosis than other commonly measured indexes of cardiac performance.

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Nonparametric Estimation from Incomplete Observations
Kaplan, E. L., & Meier, P. (1958) · Journal of the American Statistical Association · doi:10.1080/01621459.1958.10501452 · Cited by 39,158
Fundamentals of Biostatistics.
(1969) · Annals of Internal Medicine · doi:10.7326/0003-4819-70-4-873 · Cited by 4,573
A Generalized Wilcoxon Test for Comparing Arbitrarily Singly-Censored Samples
Gehan, E. A. (1965) · Biometrika · doi:10.1093/biomet/52.1-2.203 · Cited by 3,407
Plasma norepinephrine in congestive heart failure
Thomas, J. A., & Marks, B. H. (1978) · The American Journal of Cardiology · doi:10.1016/0002-9149(78)90162-5 · Cited by 925
A simplified radiometric assay for plasma norepinephrine and epinephrine
Passon, P. G., & Peuler, J. D. (1973) · Analytical Biochemistry · doi:10.1016/0003-2697(73)90517-4 · Cited by 637
Activity of the sympathetic nervous system and renin-angiotensin system assessed by plasma hormone levels and their relation to hemodynamic abnormalities in congestive heart failure
Levine, T. B., Francis, G. S., Goldsmith, S. R., Simon, A. B., & Cohn, J. N. (1982) · The American Journal of Cardiology · doi:10.1016/0002-9149(82)90243-0 · Cited by 614
Self-citation
Use of plasma norepinephrine for evaluation of sympathetic neuronal function in man
Lake, C., Ziegler, M. G., & Kopin, I. J. (1976) · Life Sciences · doi:10.1016/0024-3205(76)90210-1 · Cited by 548
Determinants of Survival in Patients with Ventricular Tachyarrhythmias
Swerdlow, C. D., Winkle, R. A., & Mason, J. W. (1983) · New England Journal of Medicine · doi:10.1056/nejm198306163082402 · Cited by 508
Comparative assessment of stimuli that release neuronal and adrenomedullary catecholamines in man.
Robertson, D., Johnson, G., Robertson, R. M., Nies, A. S., Shand, D. G., & Oates, J. A. (1979) · Circulation · doi:10.1161/01.cir.59.4.637 · Cited by 467
Augmentation of the Plasma Nor-Epinephrine Response to Exercise in Patients with Congestive Heart Failure
Chidsey, C. A., Harrison, D. C., & D, E. B. M. (1962) · New England Journal of Medicine · doi:10.1056/nejm196209272671305 · Cited by 439

Show all 23 references

Research works printed but not linked: 2

Hopkins A. Survival analysis with covariates — Cox models. In: BMDP statistical software. Berkeley, Calif.: University of California Press, 1983: 576–94.
10.2307/2281868 · DOI · Paper page

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Nishizawà, Y., Morii, H., & Durlach, J. (2007) · Springer eBooks · doi:10.1007/978-1-84628-483-0 · Cited by 69
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Cardona‐Guarache, R., Padala, S. K., Velazco‐Davila, L., Cassano, A. D., Abbate, A., Ellenbogen, K. A., & Koneru, J. N. (2017) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.13249 · Cited by 49
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Taylor, J. A., Morillo, C. A., Eckberg, D. L., & Ellenbogen, K. A. (1996) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(96)00389-0 · Cited by 49
Reflex cardiovascular control in congestive heart failure
Mancia, G., Seravalle, G., Giannattasio, C., Bossi, M., Preti, L., Cattaneo, B. M., & Grassi, G. M. (1992) · The American Journal of Cardiology · doi:10.1016/0002-9149(92)91251-x · Cited by 49
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PEHRSSON, S. K., Hjemdahl, P., Nordlander, R., & Åström, H. (1988) · Heart · doi:10.1136/hrt.60.3.212 · Cited by 49
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Stern, J. E. (2014) · Journal of Neuroendocrinology · doi:10.1111/jne.12252 · Cited by 48
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Stanek, K. M., Gunstad, J., Paul, R. H., Poppas, A., Jefferson, A. L., Sweet, L. H., Hoth, K. F., Haley, A. P., Forman, D. E., & Cohen, R. A. (2009) · The Journal of Cardiovascular Nursing · doi:10.1097/jcn.0b013e31819b54de · Cited by 48
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Long-term administration of tempol attenuates postinfarct ventricular dysfunction and sympathetic activity in rats
Shi, Z., Chen, A., Xu, Y., Chen, Q., Gao, X.-Y., Wang, W., & Zhu, G. (2009) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-008-0627-x · Cited by 48
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Coca, S. G., Perazella, M. A., & Buller, G. K. (2005) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2004.10.015 · Cited by 48
The Autonomic Nervous System
Glick, D. B. (2010) · Elsevier eBooks · doi:10.1016/b978-0-443-06959-8.00012-1 · Cited by 48
Long-term chronic baroreflex activation
Gronda, E., Seravalle, G., Trevano, F. Q., Costantino, G., Casini, A., Alsheraei, A., Lovett, E. G., Vanoli, E., Mancia, G., & Grassi, G. M. (2015) · Journal of Hypertension · doi:10.1097/hjh.0000000000000603 · Cited by 48
Effects of long-term beta-blocker (metoprolol or carvedilol) therapy on QT variability in subjects with chronic heart failure secondary to ischemic cardiomyopathy
Piccirillo, G., Quaglione, R., Nocco, M., Naso, C., Moisè, A., Lionetti, M., Carlo, S. D., & Marigliano, V. (2002) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)02778-9 · Cited by 48
Sympathetic control after cardiac resynchronization therapy: responders versus nonresponders
Najem, B., Unger, P., Preumont, N., Jansens, J.-L., Houssière, A., Pathak, A., Xhaët, O., Gabriël, L., Friart, A., Roy, L. D., et al. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00373.2006 · Cited by 48
Cardiac-specific sympathetic activation in men and women with and without heart failure
Mitoff, P. R., Gam, D., Ivanov, J., Al‐Hesayen, A., Azevedo, E. R., Newton, G. E., Parker, J. D., & Mak, S. S. (2010) · Heart · doi:10.1136/hrt.2010.199760 · Cited by 50
The role of exercise testing in chronic heart failure.
Lipkin, D. P. (1987) · Heart · doi:10.1136/hrt.58.6.559 · Cited by 48
Effects of sustained β-adrenergic stimulation on ionic currents of cultured adult guinea pig cardiomyocytes
Zhang, L., Wang, Z., & Nattel, S. (2002) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01138.2000 · Cited by 48
TNF-α enhances cardiac myocyte NO production through MAP kinase-mediated NF-κB activation
Kan, H. J., Xie, Z., & Finkel, M. S. (1999) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1999.277.4.h1641 · Cited by 48
Subnormal parasympathetic activity after cardiac transplantation
Smith, M. L., Ellenbogen, K. A., Eckberg, D. L., Sheehan, H. M., & Thames, M. D. (1990) · The American Journal of Cardiology · doi:10.1016/0002-9149(90)91108-i · Cited by 48
Heart Rate Variability in Heart Failure
Moore, R., & Nolan, J. (2004) · doi:10.1002/9780470987483.ch13 · Cited by 48
Sodium and Water Excretion Abnormalities in Congestive Heart Failure
Mettauer, B., Rouleau, J. L., Bichet, D. G., JUNEAU, C., KORTAS, C., BARJON, J.-N., & de Champlain, J. (1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-105-2-161 · Cited by 47
‘A Single Night’ Beneficial Effects of Adaptive Servo-Ventilation on Cardiac Overload, Sympathetic Nervous Activity, and Myocardial Damage in Patients With Chronic Heart Failure and Sleep-Disordered Breathing
Yoshihisa, A., Suzuki, S., Miyata, M., Yamaki, T., Sugimoto, K., Kunii, H., Nakazato, K., Suzuki, H., Saitoh, S., & Takeishi, Y. (2012) · Circulation Journal · doi:10.1253/circj.cj-12-0453 · Cited by 47
Reinforcement of the adrenergic overdrive in the metabolic syndrome complicated by obstructive sleep apnea
Grassi, G. M., Seravalle, G., Quarti‐Trevano, F., Mineo, C., Lonati, L. M., Facchetti, R., & Mancia, G. (2010) · Journal of Hypertension · doi:10.1097/hjh.0b013e328337a9fd · Cited by 46
Plasma endothelin in congestive heart failure: A predictor of cardiac death?
Galatius, S., Wroblewski, H., Emmeluth, C., Bie, P., Haunsø, S., & Kastrup, J. (1996) · Journal of Cardiac Failure · doi:10.1016/s1071-9164(96)80025-x · Cited by 47
Amelioration of depressed cardiopulmonary reflex control of sympathetic nerve activity by short-term exercise training in male rabbits with heart failure
Pliquett, R. U., Cornish, K. G., Patel, K. P., Schultz, H. D., Peuler, J. D., & Zucker, I. H. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00486.2003 · Cited by 47
Radiation-induced heart disease: morphology, changes in catecholamine synthesis and content, beta-adrenoceptor density, and hemodynamic function in an experimental model.
Schultz-Hector, S., Böhm, M., Blöchel, A., Dominiak, P., Erdmann, E., Müller-Schauenburg, W., & Weber, A. (1992) · PubMed · Cited by 47
Sympathetic activation in dogs with congestive heart failure caused by chronic mitral valve disease and dilated cardiomyopathy
Ware, W. A., Lund, D. D., Subieta, A. R., & Schmid, P. G. (1990) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.1990.197.11.1475 · Cited by 47
Revisiting salt and water retention: new diuretics, aquaretics, and natriuretics
Costello‐Boerrigter, L. C., Boerrigter, G., & Burnett, J. C. J. (2003) · Medical Clinics of North America · doi:10.1016/s0025-7125(02)00181-5 · Cited by 47
Cardiac Index vs Oxygen-Derived Parameters for Rational Use of Dobutamine in Patients With Congestive Heart Failure
Teboul, J., Graïni, L., Boujdaria, R., Berton, C., & Richard, C. (1993) · CHEST Journal · doi:10.1378/chest.103.1.81 · Cited by 47
Beta blocker treatment in heart failure
Carson, P. E. (1999) · Progress in Cardiovascular Diseases · doi:10.1053/pcad.1999.0410301 · Cited by 47
Transgenic models of α2-adrenergic receptor subtype function
Hein, L. (2008) · Springer eBooks · doi:10.1007/bfb0117493 · Cited by 47
Iodine-123-metaiodobenzylguanidine imaging can predict future cardiac events in heart failure patients with preserved ejection fraction
Katoh, S., Shishido, T., Kutsuzawa, D., Arimoto, T., Netsu, S., Funayama, A., Ishino, M., Niizeki, T., Nishiyama, S., Takahashi, H., et al. (2010) · Annals of Nuclear Medicine · doi:10.1007/s12149-010-0409-3 · Cited by 45
AT1 receptor in paraventricular nucleus mediates the enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure
Wang, H., Zhang, F., Zhang, Y., Gao, X.-Y., Wang, W., & Zhu, G. (2005) · Autonomic Neuroscience · doi:10.1016/j.autneu.2005.07.003 · Cited by 46
Exercise training prevents the deterioration in the arterial baroreflex control of sympathetic nerve activity in chronic heart failure patients
Groehs, R. V., Toschi‐Dias, E., Antunes‐Correa, L. M., Trevizan, P. F., Rondon, M. U. P. B., de Oliveira, P., Alves, M. J. N. N., Almeida, D. R., Middlekauff, H. R., & Negrão, C. E. (2015) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00723.2014 · Cited by 46
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Post-translational regulation of neuronal nitric oxide synthase: implications for sympathoexcitatory states
Sharma, N. M., & Patel, K. P. (2016) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2017.1265505 · Cited by 46
Altered firing pattern of single‐unit muscle sympathetic nerve activity during handgrip exercise in chronic heart failure
Murai, H., Takamura, M., Maruyama, M., Nakano, M., Ikeda, T., Kobayashi, D., Otowa, K., Ootsuji, H., Okajima, M., Furusho, H., et al. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2009.172627 · Cited by 46
Decreased Myocardial -Adrenergic Receptor Density in Relation to Increased Sympathetic Tone in Patients with Nonischemic Cardiomyopathy
Tsukamoto, T., Morita, K., Naya, M., Inubushi, M., Katoh, C., Nishijima, K., Kuge, Y., Okamoto, H., Tsutsui, H., & Tamaki, N. (2007) · Journal of Nuclear Medicine · doi:10.2967/jnumed.107.043794 · Cited by 46
Role of nitric oxide and oxidative stress in baroreceptor dysfunction in patients with chronic heart failure
Nightingale, A. K., Blackman, D. J., Field, R., GLOVER, N. J., Pegge, N. C., Mumford, C. E., Schmitt, M., ELLIS, G. R., Morris‐Thurgood, J., & Frenneaux, M. P. (2003) · Clinical Science · doi:10.1042/cs20020334 · Cited by 46
Reactive Oxygen Species in the Paraventricular Nucleus Mediate the Cardiac Sympathetic Afferent Reflex in Chronic Heart Failure Rats
Han, Y., Shi, Z., Zhang, F., Yang, Y., Zhong, M., Gao, X., Wang, W., & Zhu, G. (2007) · European Journal of Heart Failure · doi:10.1016/j.ejheart.2007.07.004 · Cited by 46
Calcium signaling phenomena in heart diseases: a perspective
Chakraborti, S., Das, S. K., Kar, P., Ghosh, B., Samanta, K., Kolley, S., Ghosh, S., Roy, S., & Chakraborti, T. (2006) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-006-9355-8 · Cited by 46
Parathyroid Hormone-Related Protein Is Produced in the Myocardium and Increased in Patients with Congestive Heart Failure
Oginö, K., Ogura, K., Kinugasa, Y., Furuse, Y., Uchida, K. S. K., Shimoyama, M., Kinugawa, T., Osaki, S., Kato, M., Tomikura, Y., et al. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020314 · Cited by 46
Beneficial effects of metoprolol on myocardial sympathetic function: Evidence from a randomized, placebo-controlled study in patients with congestive heart failure
de Milliano, P. A. R., de Groot, A. C., Tijssen, J. G. P., van Eck‐Smit, B. L. F., van Zwieten, P. A., & Lie, K. I. (2002) · American Heart Journal · doi:10.1067/mhj.2002.121807 · Cited by 46
Propranolol ameliorates and epinephrine exacerbates progression of acute and chronic viral myocarditis
Wang, J., Meissner, A., Malek, S., Chen, Y., Ke, Q., Zhang, J., Chu, V., Hampton, T., Crumpacker, C. S., Abelmann, W. H., et al. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00258.2005 · Cited by 46
Sudden unexpected death in heart failure may be preceded by short term, intraindividual increases in inflammation and in autonomic dysfunction: a pilot study
Shehab, A. (2004) · Heart · doi:10.1136/hrt.2003.028399 · Cited by 46
Neuroendocrine activity in congestive heart failure
Francis, G. S. (1990) · The American Journal of Cardiology · doi:10.1016/0002-9149(90)90474-f · Cited by 46
Self-citation
Factors influencing survival and mode of death in severe chronic ischaemic cardiac failure.
Glover, D. R., & Littler, W. A. (1987) · Heart · doi:10.1136/hrt.57.2.125 · Cited by 45
Targeting the autonomic nervous system: Measuring autonomic function and novel devices for heart failure management
Patel, H. C., Rosen, S. D., Lindsay, A. C., Hayward, C., Lyon, A. R., & Mario, C. D. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2013.10.058 · Cited by 45
Future G protein-coupled receptor targets for treatment of heart failure
Rengo, G., Lymperopoulos, A., & Koch, W. J. (2009) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-009-0033-5 · Cited by 44
Impact of Aldosterone Receptor Blockade Compared With Thiazide Therapy on Sympathetic Nervous System Function in Geriatric Hypertension
Wray, D. W., & Supiano, M. A. (2010) · Hypertension · doi:10.1161/hypertensionaha.109.147058 · Cited by 45
Sympathetic Activation in Congestive Heart Failure: Reproducibility of Neuroadrenergic Markers
Grassi, G. M., Bolla, G. B., Quarti‐Trevano, F., Arenare, F., Brambilla, G., & Mancia, G. (2008) · European Journal of Heart Failure · doi:10.1016/j.ejheart.2008.09.013 · Cited by 44
Electroacupuncture improves cardiac function and remodeling by inhibition of sympathoexcitation in chronic heart failure rats
Ma, L., Cui, B., Shao, Y., Ni, B., Zhang, W., Luo, Y., & Zhang, S. (2014) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00889.2013 · Cited by 45
Interaction between cardiac sympathetic drive and heart rate in heart failure
Kaye, D. M., Smirk, B., Finch, S., Williams, C., & Esler, M. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.07.058 · Cited by 45
β-Adrenergic Activation Initiates Chamber Dilatation in Concentric Hypertrophy
Badenhorst, D., Veliotes, D. G. A., Maseko, M. J., Tsotetsi, O. J., Brooksbank, R. L., Naidoo, A., Woodiwiss, A. J., & Norton, G. R. (2003) · Hypertension · doi:10.1161/01.hyp.0000056601.29613.dd · Cited by 46
Impaired autonomic control of heart rate and blood pressure in obesity: role of age and of insulin-resistance
Quilliot, D., Fluckiger, L., Zannad, F. M., Drouin, P., & Ziegler, O. (2001) · Clinical Autonomic Research · doi:10.1007/bf02322050 · Cited by 48
Reversing Advanced Heart Failure by Targeting Ca2+Cycling
Kaye, D. M., Hoshijima, M., & Chien, K. R. (2008) · Annual Review of Medicine · doi:10.1146/annurev.med.59.052407.103237 · Cited by 46
Effects of nNOS antisense in the paraventricular nucleus on blood pressure and heart rate in rats with heart failure
Wang, Y., Liu, X.-F., Cornish, K. G., Zucker, I. H., & Patel, K. P. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00497.2004 · Cited by 45
Is heart rate variability a reliable method to assess autonomic modulation in left ventricular dysfunction and heart failure?
Scalvini, S., Volterrani, M., Zanelli, E., Pagani, M., MAZZUERO, G., Coats, A. J. S., & Giordano, A. (1998) · International Journal of Cardiology · doi:10.1016/s0167-5273(98)00252-6 · Cited by 45
Fundamental considerations of β-adrenoceptor subtypes in human heart failure
Molenaar, P., & Parsonage, W. A. (2005) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2005.05.005 · Cited by 46
Recent Advances in the Understanding of Water Metabolism in Heart Failure
Schrier, R. W., & Martin, P.-Y. (1998) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-4871-3_53 · Cited by 45
Predictors of Mortality in Patients with Heart Failure
Gradman, A. H., & DEEDWANIA, P. C. (1994) · Cardiology Clinics · doi:10.1016/s0733-8651(18)30123-1 · Cited by 44
The “Unsympathetic” Nervous System of Heart Failure
Floras, J. S. (2002) · Circulation · doi:10.1161/01.cir.0000013788.71817.16 · Cited by 45
Modifications of skeletal muscle ryanodine receptor type 1 and exercise intolerance in heart failure
Rullman, E., Andersson, D. C., Melin, M., Reiken, S. R., MANCINI, D. M., Marks, A. R., Lund, L. H., & Gustafsson, T. P. (2013) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2013.06.026 · Cited by 44
Atrial Fibrillation in Congestive Heart Failure
Seiler, J., & Stevenson, W. G. (2009) · Cardiology in Review · doi:10.1097/crd.0b013e3181c21cff · Cited by 44
Cardiac Resynchronization Therapy Upregulates Cardiac Autonomic Control
Cha, Y., Oh, J. K., Miyazaki, C., Hayes, D. L., Rea, R. F., Shen, W.-K., Asirvatham, S. J., KEMP, B. J., Hodge, D. O., Chen, P., et al. (2008) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2008.01190.x · Cited by 43
Novel iodinated tracers, MIBG and BMIPP, for nuclear cardiology
Tamaki, N., & Yoshinaga, K. (2010) · Journal of Nuclear Cardiology · doi:10.1007/s12350-010-9305-4 · Cited by 43
Cardiovascular Problems on Hemodialysis
Ritz, E., & Bommer, J. (2009) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.01960309 · Cited by 44
Recent Advances and Clinical Applications of PET Cardiac Autonomic Nervous System Imaging
Boutagy, N. E., & Sinusas, A. J. (2017) · Current Cardiology Reports · doi:10.1007/s11886-017-0843-0 · Cited by 44
Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure
Kushnir, A., Santulli, G., Reiken, S. R., Coromilas, E. J., Godfrey, S., Brunjes, D. L., Colombo, P. C., yuzefpolskaya, M., Sokol, S. I., Kitsis, R. N., et al. (2018) · Circulation · doi:10.1161/circulationaha.117.032703 · Cited by 45
Exchange protein activated by cyclic-adenosine monophosphate (Epac) regulates atrial fibroblast function and controls cardiac remodelling
Surinkaew, S., Aflaki, M., Takawale, A. R., Chen, Y., Qi, X., Gillis, M., Shi, Y., Tardif, J., Chattipakorn, N., & Nattel, S. (2018) · Cardiovascular Research · doi:10.1093/cvr/cvy173 · Cited by 43
Diastolic Ventricular Interaction
Atherton, J. J., Thomson, H. L., Moore, T. D., Wright, K. N., Muehle, G. W. F., Fitzpatrick, L. E., & Frenneaux, M. P. (1997) · Circulation · doi:10.1161/01.cir.96.12.4273 · Cited by 44
Negative Chronotropic Effect of β-Blockade Therapy Reduces Myocardial Oxygen Expenditure for Nonmechanical Work
Yamakawa, H., Takeuchi, M., Takaoka, H., Hata, K., Mori, M., & Yokoyama, M. (1996) · Circulation · doi:10.1161/01.cir.94.3.340 · Cited by 44
Benefits of β-Blocker Therapy for Heart Failure
Goldstein, S. (2002) · Archives of Internal Medicine · doi:10.1001/archinte.162.6.641 · Cited by 42
Comparison of endothelial vasodilator function, inflammatory markers, and N-terminal pro-brain natriuretic peptide in patients with or without chronotropic incompetence to exercise test
Huang, P. H., Leu, H.-B., Chen, J. W., Wu, T., Lu, T.-M., Ding, Y., & Lin, S. J. (2005) · Heart · doi:10.1136/hrt.2005.064147 · Cited by 44
Yoga in Heart Failure Patients: A Pilot Study
Howie‐Esquivel, J., Lee, J., Collier, G., Mehling, W. E., & Fleischmann, K. E. (2010) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2010.04.011 · Cited by 47
Distinct beta-adrenergic receptor subtype signaling in the heart and their pathophysiological relevance.
Zheng, M., Han, Q., & Xiao, R. (2004) · PubMed · Cited by 44
Pathophysiology of water and sodium retention: edematous states with normal kidney function
Bekheirnia, M. R., & Schrier, R. W. (2006) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2005.09.008 · Cited by 44
Early autonomic and repolarization abnormalities contribute to lethal arrhythmias in chronic ischemic heart failure
Adamson, P. B., & Vanoli, E. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01185-8 · Cited by 44
Cardiac Physiology of Aging: Extracellular Considerations
Horn, M. (2015) · Comprehensive physiology · doi:10.1002/cphy.c140063 · Cited by 46
Autonomic control of ventricular function in health and disease: current state of the art
van Weperen, V. Y. H., Ripplinger, C. M., & Vaseghi, M. (2023) · Clinical Autonomic Research · doi:10.1007/s10286-023-00948-8 · Cited by 44
Heart Rate Recovery After Exercise and Endothelial Function—Two Important Factors to Predict Cardiovascular Events
Huang, P., Leu, H., Chen, J., & Lin, S. (2005) · Preventive Cardiology · doi:10.1111/j.1520-037x.2005.3847.x · Cited by 46
Comparison of Effects of Ivabradine versus Carvedilol in Murine Model with the Coxsackievirus B3-Induced Viral Myocarditis
Li, Y., Zhang, T., Na-Dan, Z., Li‐Sha, G., Qin, L., Guan, X., & Lin, J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0039394 · Cited by 43
Current and future G protein-coupled receptor signaling targets for heart failure therapy
Lymperopoulos, A., Siryk, A., & Dabul, S. (2013) · Drug Design Development and Therapy · doi:10.2147/dddt.s35905 · Cited by 44
Characterization of Adrenoceptor Involvement in Skeletal and Cardiac Myotoxicity Induced by Sympathomimetic Agents: Toward a New Bioassay for β-blockers
Tan, L., Burniston, J. G., Clark, W. A., Ng, Y., & Goldspink, D. F. (2003) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-200304000-00003 · Cited by 43
More severe cellular phenotype in human idiopathic dilated cardiomyopathy compared to ischemic heart disease
Hamdani, N., Borbély, A., Veenstra, S., Kooij, V., Vrydag, W., Zaremba, R., dos Remedios, C. G., Niessen, H. W. M., Michel, M. C., Paulus, W. J., et al. (2010) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-010-9231-8 · Cited by 43
Sympathetic nervous system function as measured by I-123 metaiodobenzylguanidine predicts transplant-free survival in heart failure patients with idiopathic dilated cardiomyopathy
Gerson, M. C., McGuire, N., & Wagoner, L. E. (2003) · Journal of Cardiac Failure · doi:10.1054/s1071-9164(03)00134-9 · Cited by 43
The myocardial matrix and the development and progression of ventricular remodeling
Sackner‐Bernstein, J. (2000) · Current Cardiology Reports · doi:10.1007/s11886-000-0007-4 · Cited by 43
Seasonal congestive heart failure mortality and hospitalisation trends, Quebec 1990–1998: Figure 1
Feldman, D. E., Platt, R. W., Déry, V., Kapetanakis, C., Lamontagne, D., Ducharme, A., Giannetti, N., Frenette, M., & Beck, E. J. (2004) · Journal of Epidemiology & Community Health · doi:10.1136/jech.58.2.129 · Cited by 43
Heterozygous α2C-adrenoceptor-deficient mice develop heart failure after transverse aortic constriction
Gilsbach, R., Brede, M., Beetz, N., Moura, E., Muthig, V., Gerstner, C., Barreto, F., Neubauer, S., Vieira‐Coelho, M. A., & Hein, L. (2007) · Cardiovascular Research · doi:10.1016/j.cardiores.2007.05.017 · Cited by 43
Chronic heart failure and exercise
Kokkinos, P. F., Choucair, W. K., Graves, P. R. T., Papademetriou, V., & Ellahham, S. (2000) · American Heart Journal · doi:10.1067/mhj.2000.106916 · Cited by 43
Sustained Sympathoinhibitory Effects of Cardiac Resynchronization Therapy in Severe Heart Failure
Grassi, G. M., Vincenti, A., Brambilla, R., Trevano, F. Q., Dell’Oro, R., Cirò, A., Trocino, G., Vincenzi, A., & Mancia, G. (2004) · Hypertension · doi:10.1161/01.hyp.0000144271.59333.a7 · Cited by 43
Central and peripheral components of cardiac failure
MANCINI, D. M., Jemtel, T. H. L., Factor, S. M., & Sonnenblick, E. H. (1986) · The American Journal of Medicine · doi:10.1016/0002-9343(86)90138-5 · Cited by 42
Differential cardiotoxic/cardioprotective effects of β-adrenergic receptor subtypes in myocytes and fibroblasts in doxorubicin cardiomyopathy
Fajardo, G., Zhao, M., Powers, J. C., & Bernstein, D. (2006) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2005.12.004 · Cited by 42
Neuroendocrine activation in relation to left ventricular function in chronic severe congestive heart failure: A subgroup analysis from the cooperative north scandinavian enalapril survival study (CONSENSUS)
Eriksson, S. V., Eneroth, P. H. E., KJEKSHUS, J. K., Offstad, J., & Swedberg, K. B. (1994) · Clinical Cardiology · doi:10.1002/clc.4960171107 · Cited by 42
Effect of Atorvastatin vs. Rosuvastatin on Cardiac Sympathetic Nerve Activity in Non-Diabetic Patients With Dilated Cardiomyopathy
Tsutamoto, T., Sakai, H., 伊部, 邦., Yamaji, M., Kawahara, C., Nakae, I., Fujii, M., Yamamoto, T., & Horie, M. (2011) · Circulation Journal · doi:10.1253/circj.cj-11-0222 · Cited by 42
Removal of the Cardiac Troponin I N-terminal Extension Improves Cardiac Function in Aged Mice
Biesiadecki, B. J., Tachampa, K., Yuan, C., Jin, J., de Tombe, P. P., & Solaro, R. J. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.086892 · Cited by 42
Prognostic Value of C-Reactive Protein as an Inflammatory and N-Terminal Probrain Natriuretic Peptide as a Neurohumoral Marker in Acute Heart Failure (from the Korean Heart Failure Registry)
Park, J. J., Choi, D., Yoon, C., Oh, I., Jeon, E., Kim, J., Cho, M., Chae, S. C., Ryu, K.-H., Yoo, B., et al. (2013) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2013.10.022 · Cited by 42
Ca2+ Channel α1B Subunit (CaV 2.2) Knockout Mouse Reveals a Predominant Role of N-Type Channels in the Sympathetic Regulation of the Circulatory System
Mori, Y. (2002) · Trends in Cardiovascular Medicine · doi:10.1016/s1050-1738(02)00173-1 · Cited by 42
Autonomic regulation of the immune system in cardiovascular diseases
Abboud, F. M., & Singh, M. V. (2017) · AJP Advances in Physiology Education · doi:10.1152/advan.00061.2017 · Cited by 43
Combined effect of resting heart rate and physical activity on ischaemic heart disease: mortality follow-up in a population study (the HUNT study, Norway)
Nauman, J., Nilsen, T. I. L., Wisløff, U., & Vatten, L. J. (2010) · Journal of Epidemiology and Community Health · doi:10.1136/jech.2009.093088 · Cited by 41

Authors: Cohn, J. N., Levine, T. B., Olivari, M. T., Garberg, V., Lura, D., Francis, G. S., Simon, A. B., & Rector, T.
Affiliations: University of Minnesota (US)
ORCID: Cohn, Jay N.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 1984-09-27
Volume: 311
Issue: 13
Pages: 819-823
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejm198409273111303
OpenAlex: W2338638760
Cited by: 3,125
References: 23
Citations by year: 2026: 22 · 2025: 30 · 2024: 22 · 2023: 44 · 2022: 50 · 2021: 49 · 2020: 54 · 2019: 58 · 2018: 42 · 2017: 57 · 2016: 75 · 2015: 73 · 2014: 101 · 2013: 87 · 2012: 88
FWCI: 34.36
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
Health Sciences › Medicine › Nephrology › Electrolyte and hormonal disorders
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
Keywords: plasma norepinephrine, congestive heart failure, prognosis, mortality risk, plasma renin activity, hemodynamics, sudden death, progressive heart failure, prognostic factors, heart rate, stroke work index, serum sodium
MeSH terms: Age Factors, Blood Pressure, Female, Follow-Up Studies, Heart Failure, Heart Rate, Hemodynamics, Humans, Male, Middle Aged, Norepinephrine, Prognosis, Pulmonary Wedge Pressure, Renin

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Plasma Norepinephrine as a Guide to Prognosis in Patients with Chronic Congestive Heart Failure

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