The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Vacuolar Myelopathy Pathologically Resembling Subacute Combined Degeneration in Patients with the Acquired Immunodeficiency Syndrome
Abstract
Twenty of 89 consecutive patients with the acquired immunodeficiency syndrome (AIDS) in whom autopsies were performed over a 3 1/2-year period had a vacuolar myelopathy that was most severe in the lateral and posterior columns of the thoracic cord. Light and electron microscopy showed that vacuoles were surrounded by a thin myelin sheath and appeared to arise from swelling within myelin sheaths. Signs and symptoms referable to the spinal-cord lesions, including paraparesis, often accompanied by spasticity or ataxia (or both), were present in all five patients with marked pathological changes, in five of seven patients with moderate changes, and in two of eight patients with mild changes. Fourteen patients were demented. The clinical presentation was sufficiently distinctive to provide a guide for antemortem diagnosis. Possible causes of the vacuolar changes include uncharacterized viral infection or a metabolic derangement related to selective nutritional deficiency.
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Cites
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Neurological complications of acquired immune deficiency syndrome: Analysis of 50 patients
Snider, W. D., Simpson, D. M., Nielsen, S., Gold, W. M. J., Metroka, C. E., & Posner, J. B. (1983) · Annals of Neurology · doi:10.1002/ana.410140404 · Cited by 1,367
HTLV-III Infection in Brains of Children and Adults with AIDS Encephalopathy
Shaw, G. M., Harper, M. E., Hahn, B. H., Epstein, L. G., Gajdusek, D. C., Price, R. W., Navia, B. A., Petito, C. K., O'Hara, C. J., Groopman, J. E., et al. (1985) · Science · doi:10.1126/science.2981429 · Cited by 897
Self-citationJOHNSON, R. T., & RICHARDSON, E. P. (1968) · Medicine · doi:10.1097/00005792-196807000-00002 · Cited by 825
THE ACQUIRED (NON-WILSONIAN) TYPE OF CHRONIC HEPATOCEREBRAL DEGENERATION
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MYELONEUROPATHY AFTER PROLONGED EXPOSURE TO NITROUS OXIDE
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SCOTT, J. (1981) · The Lancet · doi:10.1016/s0140-6736(81)90650-4 · Cited by 267
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Cited by
Bottiglieri, T. (2002) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.5.1151s · Cited by 286
Metadata
- Authors
- Petito, C. K., Navia, B. A., Cho, E.-S., Jordan, B. D., George, D. C., & Price, R. W.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1985-04-04
- Volume
- 312
- Issue
- 14
- Pages
- 874-879
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2339085593
- Cited by
- 561
- References
- 14
- FWCI
- 73.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Vacuolar Myelopathy Pathologically Resembling Subacute Combined Degeneration in Patients with the Acquired Immunodeficiency Syndrome. https://app.cochat.ai/papers/10.1056/nejm198504043121402
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- Petito, C. K., Navia, B. A., Cho, E.-S., Jordan, B. D., George, D. C., & Price, R. W. (1985). Vacuolar Myelopathy Pathologically Resembling Subacute Combined Degeneration in Patients with the Acquired Immunodeficiency Syndrome. New England Journal of Medicine. https://doi.org/10.1056/nejm198504043121402
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.