Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 589

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Echocardiographically Documented Mitral-Valve Prolapse: Long-Term Follow-up of 237 Patients

Nishimura, Rick A., McGoon, Michael D., Shub, Clarence, Miller, Fletcher A., Ilstrup, Duane M., Tajik, A.Jamil·1985·New England Journal of Medicine

Abstract

We determined the long-term prognosis for patients with mitral-valve prolapse documented by echocardiography by following 237 minimally symptomatic or asymptomatic patients for a mean of 6.2 years (range, 1 to 10.4). The actuarial eight-year probability of survival was 88 per cent, which is not significantly different from that for a matched control population. An initial left ventricular diastolic dimension exceeding 60 mm was the best echocardiographic predictor of the subsequent need for mitral-valve replacement (17 patients). Of the 97 patients with redundant mitral-valve leaflets identified echocardiographically, 10 (10.3 per cent) had sudden death, infective endocarditis, or a cerebral embolic event; in contrast, of the 140 patients with nonredundant valves, only 1 (0.7 per cent) had such complications (P less than 0.001). Most patients with echocardiographic evidence of mitral-valve prolapse have a benign course, but subsets at high risk for the development of progressive mitral regurgitation, sudden death, cerebral embolic events, or infective endocarditis can be identified by echocardiography.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1056/nejm198511213132101

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 3 references

Cited by

See all 589

Metadata

Authors
Nishimura, R. A., McGoon, M. D., Shub, C., Miller, F. A., Ilstrup, D. M., & Tajik, A. J.
Venue
New England Journal of Medicine
Published
1985-11-21
Volume
313
Issue
21
Pages
1305-1309
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2132285981
Cited by
589
References
3
FWCI
19.52
Type
journal article
Language
en
Open access
closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Echocardiographically Documented Mitral-Valve Prolapse: Long-Term Follow-up of 237 Patients. https://app.cochat.ai/papers/10.1056/nejm198511213132101
The paper
Nishimura, R. A., McGoon, M. D., Shub, C., Miller, F. A., Ilstrup, D. M., & Tajik, A. J. (1985). Echocardiographically Documented Mitral-Valve Prolapse: Long-Term Follow-up of 237 Patients. New England Journal of Medicine. https://doi.org/10.1056/nejm198511213132101

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.