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Cited by 1,959

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Primary Biliary Cirrhosis

Kaplan, Marshall M.·1987·New England Journal of Medicine
DOI 10.1056/nejm198702263160907
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Abstract

PRIMARY biliary cirrhosis, a chronic, progressive, and often fatal cholestatic liver disease, is characterized by the destruction of intrahepatic bile ducts, portal inflammation and scarring, and the eventual development of cirrhosis and liver failure. The diagnosis is usually made in a middle-aged woman (although the age range of patients is 20 to 80 years) who initially has fatigue or itching or who is asymptomatic and has been found to have unexplained hepatomegaly or an elevated serum alkaline phosphatase level. Biochemical tests of liver function typically reveal a cholestatic pattern — that is, the alkaline phosphatase and gamma-glutamyl transpeptidase levels are . . .

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Metadata

Authors
Kaplan, M. M.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
1987-02-26
Volume
316
Issue
9
Pages
521-528
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
DOI
10.1056/nejm198702263160907
OpenAlex
W2040375465
Cited by
1,959
References
10
FWCI
38.11
Type
journal article
Language
en
Open access
closed

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Kaplan, M. M. (1987). Primary Biliary Cirrhosis. New England Journal of Medicine. https://doi.org/10.1056/nejm198702263160907

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