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Cited by 365

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

The Reduction in Risk of Ovarian Cancer Associated with Oral-Contraceptive Use

The Cancer and Steroid Hormone Study of the Centers for Disease Control and the National Institute of Child Health and Human Development*·1987·New England Journal of Medicine

Abstract

Although several studies have reported that the use of oral contraceptives decreases the risk of ovarian cancer, it is not clear whether the effect varies according to the oral-contraceptive formulation or the histologic type of cancer. To characterize this association more fully, we used data from a case-control study, the Cancer and Steroid Hormone Study. From 1980 to 1982, 546 women 20 to 54 years of age with ovarian cancer were enrolled from eight population-based cancer registries. The controls were 4228 women selected from the same areas. Women who had used oral contraceptives had a risk of epithelial ovarian cancer of 0.6 (95 percent confidence interval, 0.5 to 0.7) as compared with those who had never used them. This protective effect was seen in women who had used oral contraceptives for as little as three to six months, and it continued for 15 years after use ended; it was independent of the specific oral-contraceptive formulation and of the histologic type of epithelial ovarian cancer. (We could not adequately assess the association with nonepithelial ovarian cancers because of an insufficient number of cases.) We conclude that the use of oral contraceptives decreases the risk of epithelial ovarian cancer.

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Metadata

Authors
The Cancer and Steroid Hormone Study of the Centers for Disease Control and the National Institute of Child Health and Human Development*
Venue
New England Journal of Medicine
Published
1987-03-12
Volume
316
Issue
11
Pages
650-655
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W4240178516
Cited by
365
References
12
FWCI
4.10
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Reduction in Risk of Ovarian Cancer Associated with Oral-Contraceptive Use. https://app.cochat.ai/papers/10.1056/nejm198703123161102
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The Cancer and Steroid Hormone Study of the Centers for Disease Control and the National Institute of Child Health and Human Development*. (1987). The Reduction in Risk of Ovarian Cancer Associated with Oral-Contraceptive Use. New England Journal of Medicine. https://doi.org/10.1056/nejm198703123161102

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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