The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
The Reduction in Risk of Ovarian Cancer Associated with Oral-Contraceptive Use
Abstract
Although several studies have reported that the use of oral contraceptives decreases the risk of ovarian cancer, it is not clear whether the effect varies according to the oral-contraceptive formulation or the histologic type of cancer. To characterize this association more fully, we used data from a case-control study, the Cancer and Steroid Hormone Study. From 1980 to 1982, 546 women 20 to 54 years of age with ovarian cancer were enrolled from eight population-based cancer registries. The controls were 4228 women selected from the same areas. Women who had used oral contraceptives had a risk of epithelial ovarian cancer of 0.6 (95 percent confidence interval, 0.5 to 0.7) as compared with those who had never used them. This protective effect was seen in women who had used oral contraceptives for as little as three to six months, and it continued for 15 years after use ended; it was independent of the specific oral-contraceptive formulation and of the histologic type of epithelial ovarian cancer. (We could not adequately assess the association with nonepithelial ovarian cancers because of an insufficient number of cases.) We conclude that the use of oral contraceptives decreases the risk of epithelial ovarian cancer.
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Citations
Cites
Sampling Methods for Random Digit Dialing
Waksberg, J. (1978) · Journal of the American Statistical Association · doi:10.1080/01621459.1978.10479995 · Cited by 1,390
INCESSANT OVULATION—A FACTOR IN OVARIAN NEOPLASIA ?
Fathalla, M. F. (1971) · The Lancet · doi:10.1016/s0140-6736(71)92335-x · Cited by 1,119
"INCESSANT OVULATION" AND OVARIAN CANCER
CASAGRANDE, J. (1979) · The Lancet · doi:10.1016/s0140-6736(79)91435-1 · Cited by 473
RANDOM DIGIT DIALING IN SELECTING A POPULATION-BASED CONTROL GROUP
HARTGE, P., BRINTON, L. A., ROSENTHAL, J. F., CAHILL, J. I., HOOVER, R. N., & WAKSBERG, J. (1984) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113955 · Cited by 251
The etiology and prevention of ovarian cancer
Stadel, B. V. (1975) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(75)90509-8 · Cited by 168
The woman at risk for developing ovarian cancer
McGowan, L., Parent, L., Lednar, W. M., et al. (1979) · Gynecologic Oncology · doi:10.1016/0090-8258(79)90111-2 · Cited by 144
ORAL CONTRACEPTIVES AND BREAST CANCER IN YOUNG WOMEN
Stadel, B., Webster, L., Rubin, G., Schlesselman, J., & Wingo, P. (1985) · The Lancet · doi:10.1016/s0140-6736(85)90524-0 · Cited by 118
AN EPIDEMIOLOGIC CASE-CONTROL STUDY OF OVARIAN CANCER AND REPRODUCTIVE FACTORS
Nasca, P. C., Greenwald, P., Chorost, S., Richart, R. M., & Caputo, T. A. (1984) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113791 · Cited by 93
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Comparative studies of the ethynyl estrogens used in oral contraceptives
Goldzieher, J. W., de la Peña, A., Chenault, C. B., & Woutersz, T. B. (1975) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(75)90061-7 · Cited by 44
Cited by
Epidemiology of ovarian cancer: a review
Brett M., R., Brett M., R., Jennifer B., P., Thomas A., S., Jennifer B., P., & Thomas A., S. (2017) · Cancer Biology & Medicine · doi:10.20892/j.issn.2095-3941.2016.0084 · Cited by 1,524
Breastfeeding and maternal health outcomes: A systematic review and meta-analysis
Chowdhury, R., Sinha, B., Sankar, M. J., Taneja, S., Bhandari, N., Rollins, N., Bahl, R., & Martines, J. (2015) · Acta Paediatrica · doi:10.1111/apa.13102 · Cited by 1,143
Risch, H. A. (1998) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/90.23.1774 · Cited by 771
Cohort studies: marching towards outcomes
Grimes, D. A., & Schulz, K. F. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07500-1 · Cited by 494
Stanczyk, F. Z., Archer, D. F., & Bhavnani, B. R. (2013) · Contraception · doi:10.1016/j.contraception.2012.12.011 · Cited by 201
Metadata
- Authors
- The Cancer and Steroid Hormone Study of the Centers for Disease Control and the National Institute of Child Health and Human Development*
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1987-03-12
- Volume
- 316
- Issue
- 11
- Pages
- 650-655
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4240178516
- Cited by
- 365
- References
- 12
- FWCI
- 4.10
- Type
- journal article
- Language
- en
- Open access
- closed
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- The Cancer and Steroid Hormone Study of the Centers for Disease Control and the National Institute of Child Health and Human Development*. (1987). The Reduction in Risk of Ovarian Cancer Associated with Oral-Contraceptive Use. New England Journal of Medicine. https://doi.org/10.1056/nejm198703123161102
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.