The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
The Molecular Basis of Thyroid Hormone Action
Abstract
Progress has been made in understanding the molecular basis of a number of clinical manifestations of thyroid disease, yet many questions remain. Why are there two thyroid hormone-receptor genes? Is the function of each of the two receptors indeed unique? How T3 receptors interact with other nuclear proteins and DNA-binding sites and how these interactions are influenced by T3 is incompletely understood. The developmental regulatory role of T3 receptor alpha 1 and its non-T3-binding alpha 2 variant needs to be defined. Most T3-regulated processes, especially those related to metabolism, muscle contraction, and brain development, function in concert with a number of other regulatory factors. The therapeutic applications of knowledge gained about the basic mechanisms of thyroid hormone action should ultimately extend beyond thyroid disease to processes regulated or influenced by T3; these include cardiac function, lipid metabolism, pituitary hormone secretion, and neural development.
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Citations
Cites
Tissue distribution of beta 3-adrenergic receptor mRNA in man
Krief, S., Lönnqvist, F., Raimbault, S., Baude, B., Van Spronsen, A., Arner, P., Strosberg, A. D., Ricquier, D., & Emorine, L. J. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116191 · Cited by 528
Anatomy of the steroid receptor zinc finger region
FREEDMAN, L. P. (1992) · Endocrine Reviews · doi:10.1210/edrv-13-2-129 · Cited by 308
Long-Term Growth in Juvenile Acquired Hypothyroidism:
Rivkees, S. A., Bode, H. H., & Crawford, J. D. (1988) · New England Journal of Medicine · doi:10.1056/nejm198803103181003 · Cited by 272
Thyroid hormones and growth hormone secretion
Valcavi, R., Zini, M., & Portioli, I. (1992) · Journal of Endocrinological Investigation · doi:10.1007/bf03348744 · Cited by 52
Cited by
Thyroid hormone and the cardiovascular system.
Klein, I., & Ojamaa, K. (2001) · New England Journal of Medicine · doi:10.1056/nejm200102153440707 · Cited by 2,300
Physiological and Molecular Basis of Thyroid Hormone Action
Yen, P. M. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.3.1097 · Cited by 2,011
Bianco, A. C., Salvatore, D., Gereben, B., Berry, M. J., & Larsen, P. R. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.1.0455 · Cited by 1,853
Klein, I., & Danzi, S. (2007) · Circulation · doi:10.1161/circulationaha.106.678326 · Cited by 1,324
Metabolism disrupting chemicals and metabolic disorders
Heindel, J. J., Blumberg, B., Cave, M., Machtinger, R., Mantovani, A., Mendez, M. A., Nadal, A., Palanza, P., Panzica, G., Sargis, R., et al. (2017) · Reproductive Toxicology · doi:10.1016/j.reprotox.2016.10.001 · Cited by 1,101
Metadata
- Authors
- Epstein, F. H., & Brent, G. A.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1994-09-29
- Volume
- 331
- Issue
- 13
- Pages
- 847-853
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2340100936
- Cited by
- 530
- References
- 4
- FWCI
- 12.27
- Type
- journal article
- Language
- en
- Open access
- closed
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- Epstein, F. H., & Brent, G. A. (1994). The Molecular Basis of Thyroid Hormone Action. New England Journal of Medicine. https://doi.org/10.1056/nejm199409293311306
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
