The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The Primary Immunodeficiencies
Abstract
The primary immunodeficiency disorders reflect abnormalities in the development and maturation of cells of the immune system. These defects result in an increased susceptibility to infection; recurrent pyogenic infections occur with defects of humoral immunity, and opportunistic infections with defects of cell-mediated immunity. These two broad categories of illness correspond roughly to defects in the two principal types of immunocompetent cells, B lymphocytes and T lymphocytes. Defective development of B cells results in abnormalities in humoral immunity, whereas defects in the development of T cells cause problems with cellular immunity.When pathogens are taken up by macrophages or dendritic cells, . . .
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Citations
Cites
IMMUNOLOGICAL RECONSTITUTION OF SEX-LINKED LYMPHOPENIC IMMUNOLOGICAL DEFICIENCY
Gatti, R., Meuwissen, H., Allen, H., Hong, R., & Good, R. (1968) · The Lancet · doi:10.1016/s0140-6736(68)92673-1 · Cited by 1,018
Regulation of MHC Class II Expression by Interferon-γ Mediated by the Transactivator Gene CIITA
Steimle, V., Siegrist, C.-A., Mottet, A., Lisowska-Grospierre, B., & Mach, B. (1994) · Science · doi:10.1126/science.8016643 · Cited by 898
Cited by
VACCINE-DERIVED POLIOVIRUSES AND THE ENDGAME STRATEGY FOR GLOBAL POLIO ERADICATION
Kew, O. M., Sutter, R. W., de Gourville, E. M., Dowdle, W. R., & Pallansch, M. A. (2005) · Annual Review of Microbiology · doi:10.1146/annurev.micro.58.030603.123625 · Cited by 703
Defective Lymphoid Development in Mice Lacking Jak3
Nosaka, T., van Deursen, J. M. A., Tripp, R. A., Thierfelder, W. E., Witthuhn, B. A., McMickle, A. P., Doherty, P. C., Grosveld, G. C., & Ihle, J. N. (1995) · Science · doi:10.1126/science.270.5237.800 · Cited by 637
Gardner, T. B., & Hill, D. R. (2001) · Clinical Microbiology Reviews · doi:10.1128/cmr.14.1.114-128.2001 · Cited by 565
Huang, S., Apasov, S., Koshiba, M., & Sitkovsky, M. (1997) · Blood · doi:10.1182/blood.v90.4.1600 · Cited by 531
Adenoviruses in Immunocompromised Hosts
Echavarría, M. (2008) · Clinical Microbiology Reviews · doi:10.1128/cmr.00052-07 · Cited by 512
Metadata
- Authors
- Rosen, F. S., Cooper, M. D., & Wedgwood, R. J. P.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1995-08-17
- Volume
- 333
- Issue
- 7
- Pages
- 431-440
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4295094671
- Cited by
- 324
- References
- 2
- FWCI
- 8.18
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The Primary Immunodeficiencies. https://app.cochat.ai/papers/10.1056/nejm199508173330707
- The paper
- Rosen, F. S., Cooper, M. D., & Wedgwood, R. J. P. (1995). The Primary Immunodeficiencies. New England Journal of Medicine. https://doi.org/10.1056/nejm199508173330707
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
