The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
The Treatment of Helicobacter pylori Infection in the Management of Peptic Ulcer Disease
Abstract
Antimicrobial therapy against H. pylori is indicated for all patients with documented peptic ulcer disease who have evidence of the infection. The regimen of first choice, selected on the basis of available studies, is triple therapy with bismuth, metronidazole, and tetracycline (Table 1). For patients who are known to have taken metronidazole previously, clarithromycin may be substituted for metronidazole. For patients with active, symptomatic peptic ulcers we also recommend an antisecretory drug to promote healing and relieve symptoms. Second-choice regimens consist of combinations of two antimicrobial drugs--metronidazole, amoxicillin, or clarithromycin--with an antisecretory agent, preferably an H+/K+-ATPase antagonist such as omeprazole. The combination of a single antimicrobial drug (especially amoxicillin) with omeprazole is less efficacious and cannot be recommended. Regardless of the antimicrobial regimen used, successful eradication of H. pylori infection markedly reduces the risk of recurrent peptic ulcers. If this therapeutic approach is taken with all patients with peptic ulcers, the recurrence of ulcers should become a rarity in medical practice.
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Citations
Cites
Helicobacter pylori Infection and the Risk of Gastric Carcinoma
Parsonnet, J., Friedman, G. D., Vandersteen, D. P., Chang, Y., Vogelman, J. H., Orentreich, N., & Sibley, R. K. (1991) · New England Journal of Medicine · doi:10.1056/nejm199110173251603 · Cited by 3,894
Wotherspoon, A. C., Diss, T. C., Pan, L., Isaacson, P. G., Doglioni, C., Moschini, A., & de Boni, M. (1993) · The Lancet · doi:10.1016/0140-6736(93)91409-f · Cited by 2,118
Helicobacter pylori Infection and Gastric Lymphoma
Parsonnet, J., Hansen, S., Rodriguez, L., Gelb, A. B., Warnke, R. A., Jellum, E., Orentreich, N., Vogelman, J. H., & Friedman, G. D. (1994) · New England Journal of Medicine · doi:10.1056/nejm199405053301803 · Cited by 1,831
Helicobacter pylori Infection and Gastric Carcinoma among Japanese Americans in Hawaii
Nomura, A., Stemmermann, G. N., Chyou, P.-H., Kato, I., Perez-Perez, G. I., & Blaser, M. J. (1991) · New England Journal of Medicine · doi:10.1056/nejm199110173251604 · Cited by 1,762
(2011) · Hepatogastroenterology · doi:10.5754/hge11453 · Cited by 1,254
PROSPECTIVE DOUBLE-BLIND TRIAL OF DUODENAL ULCER RELAPSE AFTER ERADICATION OF CAMPYLOBACTER PYLORI
Marshall, B., Warren, J. R., Blincow, E., Phillips, M., Goodwin, C. S., Murray, R., Blackbourn, S., Waters, T., & Sanderson, C. (1988) · The Lancet · doi:10.1016/s0140-6736(88)90929-4 · Cited by 1,037
Epidemiology of Helicobacter pylori in an asymptomatic population in the United States
Graham, D. Y., Malaty, H. M., Evans, D. G., Evans, D. J., Klein, P. D., & Adam, E. (1991) · Gastroenterology · doi:10.1016/0016-5085(91)90644-z · Cited by 960
Cure of duodenal ulcer associated with eradication of Helicobacter pylori
Rauws, E. A. J., & Tytgat, G. N. J. (1990) · The Lancet · doi:10.1016/0140-6736(90)91301-p · Cited by 922
Graham, D. Y., Lew, G. M., Klein, P. D., Evans, D. G., Evans, D. J., Saeed, Z. A., & Malaty, H. M. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-116-9-705 · Cited by 909
CAMPYLOBACTER PYLORI DETECTED NONINVASIVELY BY THE 13C-UREA BREATH TEST
Graham, D., Evans, D., Alpert, L., Klein, P., Evans, D., Opekun, A., & Boutton, T. (1987) · The Lancet · doi:10.1016/s0140-6736(87)92145-3 · Cited by 711
Cited by
Furuta, T. (2001) · Clinical Pharmacology & Therapeutics · doi:10.1067/mcp.2001.113959 · Cited by 254
Reversal of Long-Standing Iron Deficiency Anaemia after Eradication of Helicobacter pylori Infection
Marignani, M., Angeletti, S., Bordi, C., Malagnino, F., Mancino, C., Fave, G. D., & Annibale, B. (1997) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529709025109 · Cited by 133
Parkinsonism: siblings share Helicobacter pylori seropositivity and facets of syndrome
Charlett, A., Dobbs, R. J., Dobbs, S. M., Weller, C., Brady, P., & Peterson, D. W. (2009) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1999.tb00654.x · Cited by 82
Metadata
- Authors
- Walsh, J. H., & Peterson, W. L.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1995-10-12
- Volume
- 333
- Issue
- 15
- Pages
- 984-991
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1964480813
- Cited by
- 383
- References
- 59
- FWCI
- 38.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- Walsh, J. H., & Peterson, W. L. (1995). The Treatment of Helicobacter pylori Infection in the Management of Peptic Ulcer Disease. New England Journal of Medicine. https://doi.org/10.1056/nejm199510123331508
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
