The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Mechanisms of Muscle Wasting — The Role of the Ubiquitin–Proteasome Pathway
Abstract
All proteins in mammalian cells are continually being degraded and replaced. In the cytosol, nucleus, and organelles, individual proteins are degraded at widely differing rates; some cytosolic enzymes have half-lives as short as 10 minutes, whereas others last for days. The average rate of protein turnover also varies among tissues; the majority of proteins in rat hepatocytes are replaced every few days, whereas those in muscle or brain cells are replaced every one to two weeks. The amount of intracellular protein turned over each day is quite large. In a normal 70-kg adult, about 280 g of protein is synthesized . . .
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Gaczynska, M., Rock, K. L., Spies, T., & Goldberg, A. L. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.20.9213 · Cited by 312
Self-citationAlbumin homeostasis in patients undergoing continuous ambulatory peritoneal dialysis
Kaysen, G. A., & Schoenfeld, P. Y. (1984) · Kidney International · doi:10.1038/ki.1984.15 · Cited by 193
Cited by
Stitt, T. N., Drujan, D., Clarke, B. A., Panaro, F., Timofeyva, Y., Kline, W. O., Gonzalez, M., Yancopoulos, G. D., & Glass, D. J. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00211-4 · Cited by 1,964
Sarcopenia: Aging-Related Loss of Muscle Mass and Function
Larsson, L., Degens, H., Li, M., Salviati, L., Lee, Y. I., Thompson, W., Kirkland, J. L., & Sandri, M. (2019) · Physiological Reviews · doi:10.1152/physrev.00061.2017 · Cited by 1,797
Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy
Gomes, M. D., Lecker, S. H., Jagoe, R. T., Navon, A., & Goldberg, A. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.251541198 · Cited by 1,774
Self-citationMultiple types of skeletal muscle atrophy involve a common program of changes in gene expression
Lecker, S. H., Jagoe, R. T., Gilbert, A., Gomes, M., Baracos, V., Bailey, J., Price, S. R., Mitch, W. E., & Goldberg, A. L. (2004) · The FASEB Journal · doi:10.1096/fj.03-0610com · Cited by 1,539
Self-citationProteasome inhibitors: valuable new tools for cell biologists.
Lee, D. H., & Goldberg, A. L. (1998) · Trends in Cell Biology · doi:10.1016/s0962-8924(98)01346-4 · Cited by 1,474
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Metadata
- Authors
- Mitch, W. E., & Goldberg, A. L.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1996-12-19
- Volume
- 335
- Issue
- 25
- Pages
- 1897-1905
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2341277428
- Cited by
- 1,166
- References
- 2
- FWCI
- 11.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- Mitch, W. E., & Goldberg, A. L. (1996). Mechanisms of Muscle Wasting — The Role of the Ubiquitin–Proteasome Pathway. New England Journal of Medicine. https://doi.org/10.1056/nejm199612193352507
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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