Cited by 204Adrenal and Paraganglionic TumorsAdrenal Hormones and DisordersPituitary Gland Disorders and Treatments

The DOI matches its Crossref record; 23 of the 24 references it cites were found in a registry or an index.

Propranolol therapy for ectopic β-adrenergic receptors in adrenal Cushing's syndrome.

Open access

Lacroix, André, Tremblay, Johanne, Rousseau, Guy, Bouvier, Michel, Hamet, Pavel·1997·New England Journal of Medicine

DOI 10.1056/nejm199711133372004

Open this paper in CoChat — free account Open PDF

Abstract

Most patients with corticotropin-independent Cushing's syndrome have an adrenal adenoma or carcinoma,1 but a few have bilateral adrenal hyperplasia. Three patients with Cushing's syndrome and corticotropin-independent bilateral adrenal hyperplasia2–4 and two patients with adrenal adenomas5,6 in whom food stimulated cortisol secretion have been described; the abnormal adrenal tissues in these patients aberrantly overexpressed receptors for gastric inhibitory polypeptide.6,7 We describe a patient with Cushing's syndrome and corticotropin-independent bilateral adrenal hyperplasia in whom endogenous catecholamines, acting through an ectopic adrenal β-adrenergic receptor, stimulated cortisol secretion; the hyperadrenocorticism was inhibited by β-blockade. Case Report A 56-year-old man presented with . . .

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1056/nejm199711133372004

Cites

23 of 23 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

A highly sensitive adenylate cyclase assay
Salomon, Y., Londos, C., & Rodbell, M. (1974) · Analytical Biochemistry · doi:10.1016/0003-2697(74)90222-x · Cited by 4,135
Inverse agonist activity of beta-adrenergic antagonists.
Chidiac, P., Hébert, T. E., Valiquette, M., Dennis, M., & Bouvier, M. (1994) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)10022-9 · Cited by 372
Self-citation
[Cushing's syndrome].
CANDIA, S. D. (1951) · PubMed · Cited by 365
Gastric Inhibitory Polypeptide–Dependent Cortisol Hypersecretion — A New Cause of Cushing's Syndrome
Lacroix, A., Bolté, E., Tremblay, J., Dupré, J., Poitras, P., Fournier, H., Garon, J., Garrel, D. R., Bayard, F., Taillefer, R., et al. (1992) · New England Journal of Medicine · doi:10.1056/nejm199210013271402 · Cited by 359
Self-citation
Food-Dependent Cushing's Syndrome Mediated by Aberrant Adrenal Sensitivity to Gastric Inhibitory Polypeptide
Reznik, Y., Allali-Zerah, V., Chayvialle, J. A., Leroyer, R., Leymarie, P., Travert, G., Lebrethon, M.-C., Budi, I., Balliere, A.-M., & MAHOUDEAU, J. A. (1992) · New England Journal of Medicine · doi:10.1056/nejm199210013271403 · Cited by 276
Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions.
Kobilka, B. K., Frielle, T., Dohlman, H. G., Bolanowski, M. A., Dixon, R. A. F., Keller, P., Caron, M. G., & Lefkowitz, R. J. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48239-7 · Cited by 243
The human beta 3-adrenergic receptor is resistant to short term agonist-promoted desensitization.
Nantel, F., Bonin, H., Emorine, L. J., Zilberfarb, V., Strosberg, A. D., Bouvier, M., & Marullo, S. (1993) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13419-6 · Cited by 174
Self-citation
Structural and conformational features determining selective signal transduction in the beta 3-adrenergic receptor.
Blin, N., Camoin, L., Maigret, B., & Strosberg, A. D. (1993) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13306-3 · Cited by 125
Distinct regulation of beta 1- and beta 2-adrenergic receptors in Chinese hamster fibroblasts.
Suzuki, T., Nguyen, C., Nantel, F., Bonin, H., Valiquette, M., Frielle, T., & Bouvier, M. (1992) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)08956-4 · Cited by 107
Self-citation
Food-dependent Cushing's syndrome resulting from abundant expression of gastric inhibitory polypeptide receptors in adrenal adenoma cells
de Herder, W. W., Hofland, L. J., Usdin, T. B., de Jong, F. H., Uitterlinden, P., van Koetsveld, P. M., Mezey, É., Bonner, T. I., Bonjer, H. J., & Lamberts, S. W. J. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.9.8784063 · Cited by 107

Show all 24 references

Research works printed but not linked: 16

Archambeaud-Mouveroux F, Comas JM, Tessier MP, et al. Food-dependent Cushing's syndrome associated with the Carney complex. In: Proceedings of the 10th Meeting of the International Endocrine Society, San Francisco, June 12–15, 1996. Bethesda, Md.: Endocrine Society Press, 1996:899. abstract.
Hamet P, 1987, Clin Invest Med, 10, 530
10.1210/jc.81.9.3168 · DOI
N'Diaye N, Tremblay J, de Herder WW, Hamet P, Lacroix A. Adrenal overexpression of gastric inhibitory polypeptide receptor underlies food-dependent Cushing's syndrome. In: Program and abstracts of the 79th Annual Meeting of the Endocrine Society, Minneapolis, June 11–14, 1997. Bethesda, Md.: Endocrine Society Press, 1997:304. abstract.
Bouvier M, 1988, Mol Pharmacol, 33, 133
Hieble JP, 1995, Pharmacol Commun, 6, 183
Suzuki T, 1992, Mol Pharmacol, 41, 542
Blin N, 1993, Mol Pharmacol, 44, 1094
Nantel F, 1993, Mol Pharmacol, 43, 548
Hinshaw HT, Ney RL. Abnormal hormonal control in the neoplastic adrenal cortex. In: McKerns KW, ed. Hormones and cancer. New York: Academic Press, 1974:309-27.
Matsukura S, 1980, Cancer Res, 40, 3768
Millington DS, 1977, Acta Endocrinol Suppl (Copenh), 59, 319
10.1210/jc.80.9.2661 · DOI
10.1210/jc.80.8.2336 · DOI
Chidiac P, 1994, Mol Pharmacol, 45, 490
Mak JCW, 1995, Am J Physiol, 268, L41

Sorted by citations

Cushing's syndrome
Lacroix, A., Feelders, R. A., Stratakis, C. A., & Nieman, L. K. (2015) · The Lancet · doi:10.1016/s0140-6736(14)61375-1 · Cited by 1,777
Self-citation
Cushing's syndrome
Newell-Price, J. D. C., BERTAGNA, X. Y., Grossman, A. B., & Nieman, L. K. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68699-6 · Cited by 1,258
The Diagnosis and Differential Diagnosis of Cushing’s Syndrome and Pseudo-Cushing’s States
Newell-Price, J., Trainer, P., Besser, M., & Grossman, A. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.5.0346 · Cited by 833
Intraadrenal interactions in the regulation of adrenocortical steroidogenesis.
Ehrhart-Bornstein, M., Hinson, J. P., Bornstein, S. R., Scherbaum, W. A., & Vinson, G. P. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.2.0326 · Cited by 600
Ectopic and Abnormal Hormone Receptors in Adrenal Cushing's Syndrome
Lacroix, A., N’Diaye, N., Tremblay, J., & Hamet, P. (2001) · Endocrine Reviews · doi:10.1210/edrv.22.1.0420 · Cited by 350
Self-citation
Diagnosis and Treatment of Subclinical Hypercortisolism
Chiodini, I. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-2722 · Cited by 279
Leuprolide acetate therapy in luteinizing hormone-dependent Cushing's syndrome.
Lacroix, A., Hamet, P., & Boutin, J.-M. (1999) · New England Journal of Medicine · doi:10.1056/nejm199911183412104 · Cited by 244
Self-citation
Intraadrenal Corticotropin in Bilateral Macronodular Adrenal Hyperplasia
Louiset, E., Duparc, C., Young, J., Renouf, S., Nomigni, M. T., Boutelet, I., Libé, R., Bram, Z., Groussin, L., Caron, P. J., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1215245 · Cited by 247
Basic concepts and recent developments in human steroid hormone biosynthesis
Ghayee, H. K., & Auchus, R. J. (2007) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-007-9052-2 · Cited by 214
ACTH-independent macronodular adrenal hyperplasia
Lacroix, A. (2009) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2008.10.011 · Cited by 200
Self-citation
Cushing’s Syndrome Secondary to Adrenocorticotropin-Independent Macronodular Adrenocortical Hyperplasia due to Activating Mutations ofGNAS1Gene
Fragoso, M. C. B. V., Domenice, S., Latronico, A. C., Martin, R. M., Pereira, M. A. A., Zerbini, M. C. N., Lucón, A. M., & Mendonca, B. B. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021362 · Cited by 189
Clinical and Genetic Heterogeneity, Overlap with Other Tumor Syndromes, and Atypical Glucocorticoid Hormone Secretion in Adrenocorticotropin-Independent Macronodular Adrenal Hyperplasia Compared with Other Adrenocortical Tumors
Hsiao, H., Kirschner, L. S., Bourdeau, I., Keil, M. F., Boikos, S. A., Verma, S., Robinson-White, A. J., Nesterova, M., Lacroix, A., & Stratakis, C. A. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0516 · Cited by 183
Self-citation
Adrenocortical Tumors: Recent Advances in Basic Concepts and Clinical Management
Bornstein, S. R., Stratakis, C. A., & Chrousos, G. P. (1999) · Annals of Internal Medicine · doi:10.7326/0003-4819-130-9-199905040-00017 · Cited by 156
Aberrant G‐protein coupled receptor expression in relation to adrenocortical overfunction
Lacroix, A., Bourdeau, I., Lampron, A., Mazzuco, T. L., Tremblay, J., & Hamet, P. (2009) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2009.03689.x · Cited by 146
Self-citation
Beta2-adrenergic receptor regulates cardiac fibroblast autophagy and collagen degradation
Aránguiz, P., Canales, J., Copaja, M., Troncoso, R., Vicencio, J. M., Carrillo, C., Lara, H., Lavandero, S., & Dı́az-Araya, G. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2010.07.003 · Cited by 141
Are Ectopic or Abnormal Membrane Hormone Receptors Frequently Present in Adrenal Cushing's Syndrome?
Mircescu, H., Jilwan, J., N’Diaye, N., Bourdeau, I., Tremblay, J., Hamet, P., & Lacroix, A. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.10.6865 · Cited by 133
Self-citation
Gene array analysis of macronodular adrenal hyperplasia confirms clinical heterogeneity and identifies several candidate genes as molecular mediators
Bourdeau, I., Antonini, S. R. R., Lacroix, A., Kirschner, L. S., Matyakhina, L., Lorang, D., Libutti, S. K., & Stratakis, C. A. (2004) · Oncogene · doi:10.1038/sj.onc.1207277 · Cited by 130
Self-citation
Aberrant Membrane Hormone Receptors in Incidentally Discovered Bilateral Macronodular Adrenal Hyperplasia with Subclinical Cushing's Syndrome
Bourdeau, I., D'AMOUR, P., Hamet, P., Boutin, J., & Lacroix, A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.11.8062 · Cited by 125
Self-citation
ARMC5 Mutations Are Common in Familial Bilateral Macronodular Adrenal Hyperplasia
Gagliardi, L., Schreiber, A. W., Hahn, C. N., Feng, J., Cranston, T., Boon, H., Hotu, C., Oftedal, B. E., Cutfield, R., Adelson, D. L., et al. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-1265 · Cited by 121
Molecular and Clinical Evidence for anARMC5Tumor Syndrome: Concurrent Inactivating Germline and Somatic Mutations Are Associated With Both Primary Macronodular Adrenal Hyperplasia and Meningioma
Elbelt, U., Trovato, A., Kloth, M. T., Gentz, E., Finke, R., Spranger, J., Galas, D. J., Weber, S. N., Wolf, C., König, K., et al. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-2648 · Cited by 120
Unilateral Adrenalectomy as a First-Line Treatment of Cushing's Syndrome in Patients With Primary Bilateral Macronodular Adrenal Hyperplasia
Debillon, E., Vélayoudom‐Céphise, F., Salenave, S., Caron, P. J., Chaffanjon, P. C., Wagner, T., Massoutier, M., Lambert, B., Benoit, M., Young, J., et al. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-2662 · Cited by 116
Aberrant cortisol regulations in bilateral macronodular adrenal hyperplasia: a frequent finding in a prospective study of 32 patients with overt or subclinical Cushing's syndrome.
Libé, R., Coste, J., Guignat, L., Tissier, F., Lefebvre, H., Barrande, G., Ajzenberg, C., Tauveron, I., Clauser, E., Dousset, B., et al. (2010) · European Journal of Endocrinology · doi:10.1530/eje-10-0195 · Cited by 111
Role of ACTH and Other Hormones in the Regulation of Aldosterone Production in Primary Aldosteronism
Ghorayeb, N. E., Bourdeau, I., & Lacroix, A. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00072 · Cited by 109
Self-citation
In Vivo and in Vitro Screening for Illegitimate Receptors in Adrenocorticotropin-Independent Macronodular Adrenal Hyperplasia Causing Cushing’s Syndrome: Identification of Two Cases of Gonadotropin/Gastric Inhibitory Polypeptide-Dependent Hypercortisolism
Bertherat, J. Y., Contesse, V., Louiset, E., Barrande, G., Duparc, C., Groussin, L., Émy, P., BERTAGNA, X. Y., Kuhn, J., Vaudry, H., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1256 · Cited by 108
Cushing's syndrome variants secondary to aberrant hormone receptors
Lacroix, A., Baldacchino, V., Bourdeau, I., Hamet, P., & Tremblay, J. (2004) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2004.08.007 · Cited by 107
Self-citation
Adrenocortical Overexpression of Gastric Inhibitory Polypeptide Receptor Underlies Food-Dependent Cushing's Syndrome
N’Diaye, N., Tremblay, J., Hamet, P., de Herder, W. W., & Lacroix, A. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.8.5038 · Cited by 103
Self-citation
Aberrant Interleukin-1 Receptors in a Cortisol-Secreting Adrenal Adenoma Causing Cushing's Syndrome
Willenberg, H. S., Stratakis, C. A., Marx, C., Ehrhart‐Bornstein, M., Chrousos, G. P., & Bornstein, S. R. (1998) · New England Journal of Medicine · doi:10.1056/nejm199807023390105 · Cited by 103
Familial adrenocorticotropin-independent macronodular adrenal hyperplasia with aberrant serotonin and vasopressin adrenal receptors
Vezzosi, D., Cartier, D., Régnier, C., Otal, P., Bennet, A., Parmentier, F., Plantavid, M. M., Lacroix, A., Lefèbvre, H., & Caron, P. J. (2007) · European Journal of Endocrinology · doi:10.1530/eje.1.02324 · Cited by 102
Self-citation
The Role of Unilateral Adrenalectomy in ACTH‐Independent Macronodular Adrenal Hyperplasia (AIMAH)
Iacobone, M., Albiger, N. M. E., Scaroni, C. M., Mantero, F., Fassina, A., Viel, G., Frego, M., & Favia, G. (2008) · World Journal of Surgery · doi:10.1007/s00268-007-9408-5 · Cited by 97
Multiple aberrant hormone receptors in Cushing’s syndrome
Ghorayeb, N. E., Bourdeau, I., & Lacroix, A. (2015) · European Journal of Endocrinology · doi:10.1530/eje-15-0200 · Cited by 90
Self-citation
Bilateral Adrenal Cushing's Syndrome: Macronodular Adrenal Hyperplasia and Primary Pigmented Nodular Adrenocortical Disease
Lacroix, A., & Bourdeau, I. (2005) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2005.01.004 · Cited by 90
Self-citation
Clinical, Pathophysiologic, Genetic, and Therapeutic Progress in Primary Bilateral Macronodular Adrenal Hyperplasia
Bertherat, J. Y., Bourdeau, I., Bouys, L., Chasseloup, F., Kamenický, P., & Lacroix, A. (2022) · Endocrine Reviews · doi:10.1210/endrev/bnac034 · Cited by 92
Self-citation
Loss of KDM1A in GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing's syndrome: a multicentre, retrospective, cohort study
Chasseloup, F., Bourdeau, I., Tabarin, A., Regazzo, D., Dumontet, C., Ladurelle, N., Tosca, L., Amazit, L., Proust, A., Scharfmann, R., et al. (2021) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(21)00236-9 · Cited by 86
Self-citation
Diagnosis and management of primary bilateral macronodular adrenal hyperplasia
Vassiliadi, D. A., & Tsagarakis, S. (2019) · Endocrine Related Cancer · doi:10.1530/erc-19-0240 · Cited by 83
An analysis of different therapeutic options in patients with C ushing's syndrome due to bilateral macronodular adrenal hyperplasia: a single‐centre experience
Albiger, N. M., Ceccato, F., Zilio, M., Barbot, M., Occhi, G., Rizzati, S., Fassina, A., Mantero, F., Boscaro, M., Iacobone, M., et al. (2015) · Clinical Endocrinology · doi:10.1111/cen.12763 · Cited by 83
Screening for membrane hormone receptor expression in primary aldosteronism
Zwermann, O., Suttmann, Y., Bidlingmaier, M., Beuschlein, F., & Reincke, M. (2009) · European Journal of Endocrinology · doi:10.1530/eje-08-0711 · Cited by 83
Ectopic expression of vasopressin V1b and V2 receptors in the adrenal glands of familial ACTH‐independent macronodular adrenal hyperplasia
Lee, S., Hwang, R., Lee, J., Rhee, Y., Kim, D. J., Chung, U., & Lim, S. (2005) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2005.02387.x · Cited by 77
Recurrent ACTH‐independent Cushing's syndrome in multiple pregnancies and its treatment with metyrapone
Hána, V., Dokoupilová, M., Marek, J., & Plavka, R. (2001) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2001.01055.x · Cited by 77
Drugs in the medical treatment of Cushing's syndrome
SCHTEINGART, D. E. (2009) · Expert Opinion on Emerging Drugs · doi:10.1517/14728210903413522 · Cited by 76
Asynchronous Development of Bilateral Nodular Adrenal Hyperplasia in Gastric Inhibitory Polypeptide-Dependent Cushing's Syndrome
N’Diaye, N., Hamet, P., Tremblay, J., Boutin, J., Gaboury, L. A., & Lacroix, A. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.8.5930 · Cited by 76
Self-citation
Cushing's Syndrome due to a Gastric Inhibitory Polypeptide-Dependent Adrenal Adenoma: Insights into Hormonal Control of Adrenocortical Tumorigenesis
Chabre, O., Liakos, P., Vivier, J., Chaffanjon, P. C., Labat-Moleur, F., Martinie, M., Bottari, S. P., BACHELOT, I., CHAMBAZ, E. M., Defaye, G., et al. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.9.5140 · Cited by 76
Clinical and Subclinical ACTH-Independent Macronodular Adrenal Hyperplasia and Aberrant Hormone Receptors
Christopoulos, S., Bourdeau, I., & Lacroix, A. (2005) · Hormone Research in Paediatrics · doi:10.1159/000088818 · Cited by 74
Self-citation
ARMC5 mutations in a large French-Canadian family with cortisol-secreting β-adrenergic/vasopressin responsive bilateral macronodular adrenal hyperplasia
Bourdeau, I., Oble, S., Magne, F., Lévesque, I., Caceres, K., Nolet, S., Awadalla, P., Tremblay, J., Hamet, P., Fragoso, M. C. B. V., et al. (2015) · European Journal of Endocrinology · doi:10.1530/eje-15-0642 · Cited by 79
Self-citation
Primary bilateral macronodular adrenal hyperplasia
De Venanzi, A., Alencar, G. A., Bourdeau, I., Fragoso, M. C. B. V., & Lacroix, A. (2014) · Current Opinion in Endocrinology, Diabetes & Obesity · doi:10.1097/med.0000000000000061 · Cited by 73
Self-citation
Variable Expression of the V1 Vasopressin Receptor Modulates the Phenotypic Response of Steroid-Secreting Adrenocortical Tumors
Arnaldi, G., Gasc, J., de Keyzer, Y., Raffin‐Sanson, M., Perraudin, V., Kuhn, J., Raux-Demay, M. C., LUTON, J. P., Clauser, É., & BERTAGNA, X. Y. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.6.4873 · Cited by 73
Cyclic AMP‐Dependent Signaling Aberrations in Macronodular Adrenal Disease
Bourdeau, I., & Stratakis, C. A. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb04339.x · Cited by 72
Aberrant adrenal sensitivity to multiple ligands in unilateral incidentaloma with subclinical autonomous cortisol hypersecretion: a prospective clinical study.
Reznik, Y., Lefebvre, H., Rohmer, V., Charbonnel, B., Tabarin, A., Rodien, P., Lecomte, P., Bardet, S., Coffin, C., & Mahoudeau, J. (2004) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2004.02048.x · Cited by 71
Is unilateral adrenalectomy an alternative treatment for ACTH-independent macronodular adrenal hyperplasia?: Long-term follow-up of four cases
Lamas, C., Alfaro, J., Lucas, T., Beatriz Lecumberri, S., Barceló, B., & Estrada, J. S. (2002) · European Journal of Endocrinology · doi:10.1530/eje.0.1460237 · Cited by 70
Inherited Adrenocorticotropin-Independent Macronodular Adrenal Hyperplasia with Abnormal Cortisol Secretion by Vasopressin and Catecholamines: Detection of the Aberrant Hormone Receptors on Adrenal Gland
Miyamura, N., Taguchi, T., Murata, Y., Taketa, K., Iwashita, S., Matsumoto, K., Nishikawa, T., Toyonaga, T., Sakakida, M., & Araki, E. (2002) · Endocrine · doi:10.1385/endo:19:3:319 · Cited by 68
The role of ARMC5 in human cell cultures from nodules of primary macronodular adrenocortical hyperplasia (PMAH)
Cavalcante, I. P., Nishi, M. Y., Zerbini, M. C. N., Almeida, M. Q., Balderrama-Brondani, V., Botelho, M. L. A. D. A., Tanno, F. Y., Srougi, V., Chambo, J. L., Mendonca, B. B., et al. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.06.027 · Cited by 65
Loss of Expression of the Ubiquitous Transcription Factor cAMP Response Element-Binding Protein (CREB) and Compensatory Overexpression of the Activator CREM in the Human Adrenocortical Cancer Cell Line H295R
Groussin, L., Massias, J. F., BERTAGNA, X. Y., & Bertherat, J. Y. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.1.6307 · Cited by 64
Expression of Serotonin7Receptor and Coupling of Ectopic Receptors to Protein Kinase A and Ionic Currents in Adrenocorticotropin-Independent Macronodular Adrenal Hyperplasia Causing Cushing’s Syndrome
Louiset, E., Contesse, V., Groussin, L., Cartier, D., Duparc, C., Barrande, G., Bertherat, J. Y., Vaudry, H., & Lefèbvre, H. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-0538 · Cited by 62
Classic and Recent Etiologies of Cushing??s Syndrome
Beauregard, C., Dickstein, G., & Lacroix, A. (2002) · Treatments in Endocrinology · doi:10.2165/00024677-200201020-00002 · Cited by 61
Self-citation
Adrenal incidentalomas
Bertherat, J. Y., Mosnier-Pudar, H., & BERTAGNA, X. Y. (2002) · Current Opinion in Oncology · doi:10.1097/00001622-200201000-00011 · Cited by 60
Food-Dependent Cushing's Syndrome: Possible Involvement of Leptin in Cortisol Hypersecretion
Pralong, F. P., Gómez, F., Guillou, L., Mosimann, F., Franscella, S., & Gaillard, R. C. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.10.6068 · Cited by 61
MECHANISMS IN ENDOCRINOLOGY: Autocrine/paracrine regulatory mechanisms in adrenocortical neoplasms responsible for primary adrenal hypercorticism
Lefèbvre, H., Prévost, G., & Louiset, E. (2013) · European Journal of Endocrinology · doi:10.1530/eje-13-0308 · Cited by 58
Aberrant G-protein coupled hormone receptor in adrenal diseases
St‐Jean, M., Ghorayeb, N. E., Bourdeau, I., & Lacroix, A. (2018) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2018.01.003 · Cited by 58
Self-citation
Synaptophysin Immunoreactivity in Primary Pigmented Nodular Adrenocortical Disease: Neuroendocrine Properties of Tumors Associated with Carney Complex
Stratakis, C. A., Carney, J. A., Kirschner, L. S., Willenberg, H. S., Brauer, S., Ehrhart‐Bornstein, M., & Bornstein, S. R. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.3.5549 · Cited by 58
Primary bilateral macronodular adrenal hyperplasia: definitely a genetic disease
Cavalcante, I. P., Berthon, A. S., Fragoso, M. C. B. V., Reincke, M., Stratakis, C. A., Ragazzon, B., & Bertherat, J. Y. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-022-00718-y · Cited by 56
Eutopic Overexpression of Vasopressin V1aReceptor in Adrenocorticotropin-Independent Macronodular Adrenal Hyperplasia
Mune, T., Murase, H., Yamakita, N., Fukuda, T., Murayama, M. A., Miura, A., Suwa, T., Hanafusa, J., Daido, H., Morita, H., et al. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020067 · Cited by 57
Pheochromocytoma and sub-clinical Cushing’s syndrome during pregnancy: Diagnosis, medical pre-treatment and cure by laparoscopic unilateral adrenalectomy
FINKENSTEDT, G., Gasser, R. W., Höfle, G., Lhotta, K., Kölle, D., Gschwendtner, A., & Janetschek, G. (1999) · Journal of Endocrinological Investigation · doi:10.1007/bf03343608 · Cited by 54
PATHOGENESIS OF ADRENOCORTICAL INCIDENTALOMAS AND GENETIC SYNDROMES ASSOCIATED WITH ADRENOCORTICAL NEOPLASMS
Gicquel, C., Bertherat, J. Y., Bouc, Y. L., & BERTAGNA, X. Y. (2000) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70112-2 · Cited by 53
Regulation of Aldosterone Secretion by Several Aberrant Receptors Including for Glucose-Dependent Insulinotropic Peptide in a Patient with an Aldosteronoma
Lampron, A., Bourdeau, I., Oble, S., Godbout, A., Schürch, W., Arjane, P., Hamet, P., & Lacroix, A. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1340 · Cited by 52
Self-citation
Adrenally Directed Medical Therapies for Cushing Syndrome
Tritos, N. A. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa778 · Cited by 51
ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia
Lao, L., Bourdeau, I., Gagliardi, L., He, X., Shi, W., Hao, B., Tan, M., Hu, Y., Peng, J., Coulombe, B., et al. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac483 · Cited by 52
Self-citation
Update on the Corticomedullary Interaction in the Adrenal Gland
Haase, M., Willenberg, H. S., & Bornstein, S. R. (2010) · Endocrine development · doi:10.1159/000321211 · Cited by 49
ACTH-independent macronodular adrenocortical hyperplasia reveals prevalent aberrant in vivo and in vitro responses to hormonal stimuli and coupling of arginine-vasopressin type 1a receptor to 11β-hydroxylase
Hofland, J., Hofland, L. J., van Koetsveld, P. M., Steenbergen, J., de Herder, W. W., van Eijck, C. H. J., de Krijger, R. R., van Nederveen, F. H., van Aken, M. O., de Groot, J. W. B., et al. (2013) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-8-142 · Cited by 49
Signaling Pathways in Adrenocortical Cancer
Kirschner, L. S. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb04338.x · Cited by 49
Role of unilateral adrenalectomy in bilateral adrenal hyperplasias with Cushing’s syndrome
Meloche‐Dumas, L., Mercier, F., & Lacroix, A. (2021) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2021.101486 · Cited by 47
Self-citation
Food-Dependent Androgen and Cortisol Secretion by a Gastric Inhibitory Polypeptide-Receptor Expressive Adrenocortical Adenoma Leading to Hirsutism and Subclinical Cushing's Syndrome: In Vivo and in Vitro Studies
Tsagarakis, S., Tsigos, C., Vassiliou, V., Tsiotra, P. C., Pratsinis, H., Kletsas, D., Trivizas, P., Nikou, A., Mavromatis, T. N., Sotsiou, F., et al. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.2.7171 · Cited by 47
ARMC5 mutations in familial and sporadic primary bilateral macronodular adrenal hyperplasia
Yu, L., Zhang, J., Guo, X., Chen, X., He, Z., & He, Q. (2018) · PLoS ONE · doi:10.1371/journal.pone.0191602 · Cited by 46
GIP‐dependent adrenal Cushing's syndrome with incomplete suppression of ACTH
CROUGHS, R. J. M., ZELISSEN, P. M. J., Vroonhoven, T. J. M. V. V., Hofland, L. J., N’Diaye, N., Lacroix, A., & de Herder, W. W. (2000) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2000.00932.x · Cited by 46
Self-citation
Familial vasopressin‐sensitive ACTH‐independent macronodular adrenal hyperplasia (VPs‐AIMAH): clinical studies of three kindreds
Gagliardi, L., Hotu, C., Casey, G. J., Braund, W. J., Ling, K., Dodd, T. J., Manavis, J., Devitt, P. G., Cutfield, R. G., Rudzki, Z., et al. (2008) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2008.03471.x · Cited by 45
New developments in the medical treatment of Cushing's syndrome
van der Pas, R., de Herder, W. W., Hofland, L. J., & Feelders, R. A. (2012) · Endocrine Related Cancer · doi:10.1530/erc-12-0191 · Cited by 43
Role of ACTH in the Interactive/Paracrine Regulation of Adrenal Steroid Secretion in Physiological and Pathophysiological Conditions
Lefèbvre, H., Thomas, M., Duparc, C., Bertherat, J. Y., & Louiset, E. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00098 · Cited by 43
The Aberrant Expression of the Gastric Inhibitory Polypeptide (GIP) Receptor in Adrenal Hyperplasia: Does Chronic Adrenocorticotropin Exposure Stimulate Up-Regulation of GIP Receptors in Cushing’s Disease?
Swords, F. M., Aylwin, S., Perry, L., Arola, J. T., Grossman, A. B., Monson, J., & Clark, A. J. L. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0946 · Cited by 43
Aberrant Expression of Hormone Receptors in Adrenal Cushing's Syndrome
Christopoulos, S., Bourdeau, I., & Lacroix, A. (2004) · Pituitary · doi:10.1007/s11102-005-1083-7 · Cited by 42
Self-citation
Aberrant GPCR expression is a sufficient genetic event to trigger adrenocortical tumorigenesis
Mazzuco, T. L., Chabre, O., Feige, J., & Thomas, M. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.12.034 · Cited by 41
During a corticotropin-releasing hormone test in healthy subjects, administration of a beta-adrenergic antagonist induced secretion of cortisol and dehydroepiandrosterone sulfate and inhibited secretion of ACTH
Kizildere, S., Glück, T., Zietz, B., Schölmerich, J., & Straub, R. H. (2003) · European Journal of Endocrinology · doi:10.1530/eje.0.1480045 · Cited by 41
Adrenal Cushing's Syndrome Due to Bilateral Macronodular Adrenal Hyperplasia: Prediction of the Efficacy of .BETA.-blockade Therapy and Interest of Unilateral Adrenalectomy
Mazzuco, T. L., Chaffanjon, P. C., Martinie, M., Stürm, N., & Chabre, O. (2009) · Endocrine Journal · doi:10.1507/endocrj.k08e-370 · Cited by 40
Cushing’s Syndrome in a Patient with Bilateral Macronodular Adrenal Hyperplasia Responding to Cisapride: An in Vivo and in Vitro Study
Mannelli, M., Ferruzzi, P., Luciani, P., Crescioli, C., Buci, L., Corona, G., Serio, M., & Peri, A. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021949 · Cited by 40
Case Report: Adrenal LH/hCG Receptor Overexpression and Gene Amplification Causing Pregnancy-Induced Cushing’s Syndrome
Chui, M. H., Özbey, N., Ezzat, S., Kapran, Y., Erbil, Y., & Asa, S. L. (2009) · Endocrine Pathology · doi:10.1007/s12022-009-9090-2 · Cited by 39
Cellular and molecular abnormalities of a macronodular adrenal hyperplasia causing beta-blocker-sensitive Cushing's syndrome
Mazzuco, T. L., Thomas, M., Martinie, M., Cherradi, N., Stürm, N., Feige, J., & Chabre, O. (2007) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302007000900007 · Cited by 39
A Case of ACTH-Independent Macronodular Adrenal Hyperplasia: Simultaneous Expression of Several Aberrant Hormone Receptors in the Adrenal Gland
Miyamura, N., Tsutsumi, A., SENOKUCHI, H., Nakamaru, K., Kawashima, J., Sakai, K., Taguchi, T., TOKUNAGA, H., Nishida, K., Uehara, M., et al. (2003) · Endocrine Journal · doi:10.1507/endocrj.50.333 · Cited by 38
Pharmacologic Management of Cushing Syndrome
Sonino, N., Boscaro, M., & Fallo, F. (2005) · Treatments in Endocrinology · doi:10.2165/00024677-200504020-00003 · Cited by 35
Case of Adrenocorticotropic Hormone-Independent
Nakamura, Y., Son, Y., Kohno, Y., Shimono, D., Kuwamura, N., Koshiyama, H., Sasano, H., & Matsuda, T. (2001) · Endocrine · doi:10.1385/endo:15:1:057 · Cited by 35
Katecholaminabhängiges hereditäres Cushing-Syndrom - Verlaufsbeobachtung nach einseitiger Adrenalektomie
Imöhl, M., Köditz, R., Stachon, A., Müller, K., Nicolas, V., Pfeilschifter, J., & Krieg, M. (2002) · Medizinische Klinik - Intensivmedizin und Notfallmedizin · doi:10.1007/s00063-002-1220-2 · Cited by 33
Medical suppression of hypercortisolemia in Cushing’s syndrome with particular consideration of etomidate
Heyn, J., Geiger, C., Hinske, L. C., Briegel, J., & Weis, F. C. (2011) · Pituitary · doi:10.1007/s11102-011-0314-3 · Cited by 32
Analysis of the putative regulatory region of the gastric inhibitory polypeptide receptor gene in food-dependent Cushing’s syndrome
Antonini, S. R. R., N’Diaye, N., Baldacchino, V., Hamet, P., Tremblay, J., & Lacroix, A. (2004) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2004.03.120 · Cited by 33
Self-citation
Unilateral Adrenalectomy Improves Insulin Resistance and Diabetes Mellitus in a Patient with ACTH-Independent Macronodular Adrenal Hyperplasia
Ogura, M., Kusaka, I., Nagasaka, S., Yatagai, T., Shinozaki, S., Itabashi, N., Nakamura, T., Yokoyama, M., Ishikawa, S., & Ishibashi, S. (2003) · Endocrine Journal · doi:10.1507/endocrj.50.715 · Cited by 31
Vasopressin responsiveness of subclinical Cushing's syndrome due to ACTH‐independent macronodular adrenocortical hyperplasia
Tatsuno, I., Uchida, D., Tanaka, T., Koide, H., Shigeta, A., Ichikawa, T., Sasano, H., & Saitō, Y. (2003) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2003.01963.x · Cited by 31
Cushing’s syndrome: an update on current pharmacotherapy and future directions
Creemers, S. G., Hofland, L. J., Lamberts, S. W. J., & Feelders, R. A. (2015) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2015.1061995 · Cited by 30
cAMP PATHWAY ALTERATIONS FROM THE CELL SURFACE TO THE NUCLEUS IN ADRENOCORTICAL TUMORS
Rosenberg, D., Groussin, L., BERTAGNA, X. Y., & Bertherat, J. Y. (2002) · Endocrine Research · doi:10.1081/erc-120017071 · Cited by 30
Prevalencia, etiología y cuadro clínico del síndrome de Cushing
Vargas, M. L., & da Costa, C. V. (2009) · Endocrinología y Nutrición · doi:10.1016/s1575-0922(09)70191-3 · Cited by 28
Adrenocorticotropic Hormone Independent Macronodular Adrenal Hyperplasia due to Aberrant Receptor Expression: Is Medical Treatment Always an Option?
Karapanou, O., Vlassopoulou, B., Tzanela, M., Stratigou, T., Tsatlidis, V., Tsirona, S., & Tsagarakis, S. (2013) · Endocrine Practice · doi:10.4158/ep12346.cr · Cited by 27
Adrenocorticotropin-independent Cushing’s syndrome in pregnancy related to overexpression of adrenal luteinizing hormone/human chorionic gonadotropin receptors
Rask, E., Schvarcz, E., Hellman, P., Hennings, J., Karlsson, F. A., & Rao, C. V. (2009) · Journal of Endocrinological Investigation · doi:10.1007/bf03345718 · Cited by 27
Aberrant expression of multiple hormone receptors in ACTH-independent macronodular adrenal hyperplasia causing Cushing's syndrome
de Groot, J. W. B., Links, T. P., Themmen, A. P. N., Looijenga, L. H. J., de Krijger, R. R., van Koetsveld, P. M., Hofland, J., van den Berg, G., Hofland, L. J., & Feelders, R. A. (2010) · European Journal of Endocrinology · doi:10.1530/eje-10-0058 · Cited by 26
Long-term low-dose ketoconazole treatment in bilateral macronodular adrenal hyperplasia
Comte-Perret, S., Zanchi, A., & Gómez, F. (2014) · Endocrinology Diabetes and Metabolism Case Reports · doi:10.1530/edm-14-0083 · Cited by 23
Laparoscopic vs. open abdominal surgery in male pigs: Marked differences in cortisol and catecholamine response depending on the size of surgical incision
Krikri, A., Alexopoulos, V., Zoumakis, E., Katsaronis, P., Balafas, E., Kouraklis, G. P., Karayannacos, P., Chrousos, G. P., & Skalkeas, G. (2013) · HORMONES · doi:10.14310/horm.2002.1412 · Cited by 23
Adrenal Surgery for Cushing’s Syndrome
Dalmazi, G. D., & Reincke, M. (2018) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2018.01.004 · Cited by 23

Authors: Lacroix, A., Tremblay, J., Rousseau, G., Bouvier, M., & Hamet, P.
Affiliations: Centre Hospitalier de l’Université de Montréal (CA)
Université de Montréal (CA)
ORCID: Lacroix, André
Tremblay, Johanne
Rousseau, Guy
Bouvier, Michel
Hamet, Pavel
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 1997-11-13
Volume: 337
Issue: 20
Pages: 1429-1434
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejm199711133372004
OpenAlex: W2320000533
Cited by: 204
References: 24
Citations by year: 2026: 1 · 2025: 4 · 2024: 1 · 2023: 1 · 2022: 8 · 2021: 5 · 2020: 6 · 2019: 4 · 2018: 5 · 2017: 5 · 2016: 6 · 2015: 9 · 2014: 8 · 2013: 6 · 2012: 6
FWCI: 9.90
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Funders: Sanofi
Topics: Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
Keywords: Cushing's syndrome, bilateral adrenal hyperplasia, propranolol, beta-adrenergic blockade, hyperadrenocorticism, catecholamines, cortisol secretion, adrenal adenoma
MeSH terms: Adrenal Glands, Adrenergic beta-Antagonists, Catecholamines, Cushing Syndrome, Humans, Hydrocortisone, Hyperplasia, Male, Middle Aged, Propranolol, Receptors, Adrenergic, beta

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Propranolol therapy for ectopic β-adrenergic receptors in adrenal Cushing's syndrome.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks