The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
A Randomized Trial of Intensive versus Standard Blood-Pressure Control
Open accessAbstract
A Randomized Trial of Intensive versus Standard Blood-Pressure ControlTo the Editor: Wright et al. (Nov.26 issue) 1 report on the Systolic Blood Pressure Intervention Trial (SPRINT).By focusing on blood-pressure levels, rather than on specific antihypertensive agents, this trial follows a rich heritage of government-funded, noncommercial, randomized trials in hypertension that address major public health issues.The clear differences in outcomes, including lower rates of death among patients who were randomly assigned to intensive treatment than among those assigned to standard treatment, underscore the major impact of implementing this lower blood-pressure target for the appropriate population.Achievement of a difference of 15 mm Hg between patients who were randomly assigned to the intensive-treatment group (target systolic blood pressure <120 mm Hg) and patients who were randomly assigned to the standard-treatment group (target <140 mm Hg) was central to testing the authors' hypothesis.Their design article specifies that in the standard-treatment group, antihypertensive therapy should be withdrawn in a patient whose systolic blood pressure is less than 130 mm Hg on any occasion or less than 135 mm Hg on two consecutive visits. 2 Since withdrawal of antihypertensive therapy in asymptomatic patients in whom these pressures are achieved is not necessarily considered to be standard, interpretation of the overall trial results could be affected by knowledge of how often, and in how many patients, this nonstandard action was taken.
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A Randomized Trial of Intensive versus Standard Blood-Pressure Control
The SPRINT Research Group (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1511939 · Cited by 6,325
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Eplerenone in patients with systolic heart failure and mild symptoms
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Cited by
Mancia, G., Kreutz, R., Brunström, M., Burnier, M., Grassi, G., Januszewicz, A., Muiesan, M. L., Tsioufis, K., Agabiti-Rosei, E., Algharably, E. A. E., et al. (2023) · Journal of Hypertension · doi:10.1097/hjh.0000000000003480 · Cited by 3,473
Global Burden of Hypertension and Systolic Blood Pressure of at Least 110 to 115 mm Hg, 1990-2015
Forouzanfar, M. H., Liu, P., Roth, G. A., Ng, M., Biryukov, S., Marczak, L., Alexander, L., Estep, K., Hassen Abate, K., Akinyemiju, T. F., et al. (2017) · JAMA · doi:10.1001/jama.2016.19043 · Cited by 2,381
Williamson, J. D., Supiano, M. A., Applegate, W. B., Berlowitz, D. R., Campbell, R. C., Chertow, G. M., Fine, L. J., Haley, W. E., Hawfield, A. T., Ix, J. H., et al. (2016) · JAMA · doi:10.1001/jama.2016.7050 · Cited by 1,261
Bundy, J. D., Li, C., Stuchlik, P., Bu, X., Kelly, T. N., Mills, K. T., He, H., Chen, J., Whelton, P. K., & He, J. (2017) · JAMA Cardiology · doi:10.1001/jamacardio.2017.1421 · Cited by 783
Delgado, C., Baweja, M., Crews, D. C., Eneanya, N. D., Gadegbeku, C. A., Inker, L. A., Mendu, M. L., Miller, W. G., Moxey-Mims, M. M., Roberts, G. V., et al. (2022) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2021.08.003 · Cited by 783
Metadata
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2016-06-09
- Volume
- 374
- Issue
- 23
- Pages
- 2290-2295
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2223710100
- Cited by
- 654
- References
- 8
- FWCI
- 72.21
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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