Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Abstract
example, the Food and Drug Administration prioritized enforcement against certain unauthorized flavored, cartridge-based e-cigarettes in January 2020 and in July 2020 sent warning letters to 10 companies to stop the sale or distribution of flavored disposable e-cigarettes and e-liquid products that appeal to youth. 5 These findings reinforce the rapidly dynamic nature of the e-cigarette landscape and the need for clinicians, public health practitioners, and the general public to keep pace with these changes.Although the 2020 NYTS data-collection period was truncated owing to the Covid-19 pandemic, this did not affect the survey design or its national representativeness. 3
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A reanalysis of the BNT162b2 trial data suggests that a single dose of this vaccine has an efficacy of 92.6% in the early post-vaccination period.
“A reanalysis of the BNT162b2 trial data suggests that a single dose of this vaccine has an efficacy of 92.6% in the early post-vaccination period.”
Cites
Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Polack, F. P., Thomas, S. J., Kitchin, N., Absalon, J., Gurtman, A., Lockhart, S., Perez, J. L., Pérez Marc, G., Moreira, E. D., Zerbini, C., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2034577 · Cited by 14,592 · see citing works
Chi-squared and Fisher-Irwin tests of two-by-two tables with small sample recommendations
Campbell, I. (2007) · Statistics in Medicine · doi:10.1002/sim.2832 · Cited by 912 · see citing works
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Lopez Bernal, J., Andrews, N., Gower, C., Robertson, C., Stowe, J., Tessier, E., Simmons, R., Cottrell, S., Roberts, R., O’Doherty, M., et al. (2021) · BMJ · doi:10.1136/bmj.n1088 · Cited by 1,389 · see citing works
Immunological mechanisms of vaccine-induced protection against COVID-19 in humans
Sadarangani, M., Marchant, A., & Kollmann, T. R. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-021-00578-z · Cited by 560 · see citing works
A human coronavirus evolves antigenically to escape antibody immunity
Eguia, R., Crawford, K. H. D., Stevens-Ayers, T., Kelnhofer-Millevolte, L., Greninger, A. L., Englund, J. A., Boeckh, M. J., & Bloom, J. D. (2020) · doi:10.1101/2020.12.17.423313 · Cited by 258 · see citing works
Bernal, J. L., Andrews, N., Gower, C., Stowe, J., Robertson, C., Tessier, E., Simmons, R., Cottrell, S., Roberts, R., O’Doherty, M., et al. (2021) · doi:10.1101/2021.03.01.21252652 · Cited by 1,389 · see citing works
Skowronski, D. M., Febriani, Y., Ouakki, M., Setayeshgar, S., El Adam, S., Zou, M., Talbot, D., Prystajecky, N., Tyson, J. R., Gilca, R., et al. (2022) · Clinical Infectious Diseases · doi:10.1093/cid/ciac290 · Cited by 155 · see citing works
Self-citationCardiovascular Manifestation of the BNT162b2 mRNA COVID-19 Vaccine in Adolescents
Mansanguan, S., Charunwatthana, P., Piyaphanee, W., Dechkhajorn, W., Poolcharoen, A., & Mansanguan, C. (2022) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed7080196 · Cited by 83 · see citing works
- Authors
- Skowronski, D. M., & Serres, G. D.
- Affiliations
- Université Toulouse III - Paul Sabatier (FR)
- Institut National de Santé Publique du Québec (CA)
- Corresponding author
- Danuta M Skowronski
- ORCID
- Gaston De Serres
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2021-04-22
- Volume
- 384
- Issue
- 16
- Pages
- 1576-1578
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W3129580280
- Cited by
- 831
- References
- 2
- Citations by year
- 2026: 7 · 2025: 26 · 2024: 75 · 2023: 144 · 2022: 282 · 2021: 266 · 2020: 31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Social Sciences › Health › Vaccine Coverage and Hesitancy
- Keywords
- BNT162b2, mRNA vaccines, COVID-19 vaccines, vaccine safety, vaccine efficacy
- MeSH terms
- COVID-19, SARS-CoV-2, COVID-19 Vaccines, BNT162 Vaccine, Humans, RNA, Messenger
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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