Psoralen and Ultraviolet A Light Therapy for Psoriasis

Anti-TNF Antibody Therapy in Rheumatoid Arthritis and the Risk of Serious Infections and Malignancies

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Psoriasis

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Malignant Melanoma in Patients Treated for Psoriasis with Methoxsalen (Psoralen) and Ultraviolet A Radiation (PUVA)

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A clinical review of phototherapy for psoriasis

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Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions†

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Chronic phototoxicity and aggressive squamous cell carcinoma of the skin in children and adults during treatment with voriconazole

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Photochemical and Photodynamical Properties of Sulfur‐Substituted Nucleic Acid Bases,

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Mass spectrometry for the assessment of the occurrence and biological consequences of DNA adducts

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Apoptotic or Antiproliferative Activity of Natural Products against Keratinocytes for the Treatment of Psoriasis

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Mechanisms of interstrand DNA crosslink repair and human disorders

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Comparison of ethosomes and liposomes for skin delivery of psoralen for psoriasis therapy

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8-Methoxypsoralen Plus Ultraviolet A Therapy Acts via Inhibition of the IL-23/Th17 Axis and Induction of Foxp3+ Regulatory T Cells Involving CTLA4 Signaling in a Psoriasis-Like Skin Disorder

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Fanconi anemia: current insights regarding epidemiology, cancer, and DNA repair

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Neue Ziele für die Photopharmakologie

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Evaluation of psoralen ethosomes for topical delivery in rats by using in vivo microdialysis

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Dual mode of cell death upon the photo-irradiation of a Ru II polypyridyl complex in interphase or mitosis

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Ozone Layer Depletion and Emerging Public Health Concerns - An Update on Epidemiological Perspective of the Ambivalent Effects of Ultraviolet Radiation Exposure

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Isolation and Functional Characterization of CYP71AJ4 Encoding for the First P450 Monooxygenase of Angular Furanocoumarin Biosynthesis

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DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway

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Scientific Evidence of the Therapeutic Effects of Dead Sea Treatments: A Systematic Review

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4-thiothymidine sensitization of DNA to UVA offers potential for a novel photochemotherapy

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The expression of opsins in the human skin and its implications for photobiomodulation: A Systematic Review

Suh, S., Choi, E. H., & Mesinkovska, N. A. (2020) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/phpp.12578 · Cited by 75

Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy

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The Fanconi anemia pathway and ICL repair: implications for cancer therapy

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Efficacy of psoralen plus ultraviolet A therapy vs. biologics in moderate to severe chronic plaque psoriasis: retrospective data analysis of a patient registry

Inzinger, M., Heschl, B., Weger, W., Hofer, A., Legat, F. J., Gruber‐Wackernagel, A., Tilz, H., Salmhofer, W., Quehenberger, F., & Wolf, P. (2011) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2011.10396.x · Cited by 59

Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammation

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Phototherapy and Photochemotherapy for Psoriasis

Rácz, E., & Prens, E. P. (2014) · Dermatologic Clinics · doi:10.1016/j.det.2014.09.007 · Cited by 58

Treatment with 311-nm ultraviolet B accelerates and improves the clearance of psoriatic lesions in patients treated with etanercept

Wolf, P., Hofer, A., Legat, F. J., Bretterklieber, A., Weger, W., Salmhofer, W., & Kerl, H. (2008) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2008.08926.x · Cited by 53

Synthesis of 2,3-bis-organochalcogenyl-benzo[ b ]chalcogenophenes promoted by Oxone®

Perin, G., Soares, L. K., Hellwig, P. S., Silva, M. S., Neto, J. S. S., Roehrs, J. A., Barcellos, T., & Lenardao, E. J. (2019) · New Journal of Chemistry · doi:10.1039/c9nj00526a · Cited by 53

Photobiomodulation devices for hair regrowth and wound healing: a therapy full of promise but a literature full of confusion

Mignon, C., Botchkareva, N. V., Uzunbajakava, N. E., & Tobin, D. J. (2016) · Experimental Dermatology · doi:10.1111/exd.13035 · Cited by 51

Trends in phototherapy utilization among Medicare beneficiaries in the United States, 2000 to 2015

Tan, S., Buzney, E. A., & Mostaghimi, A. (2018) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2018.03.018 · Cited by 50

The osteoprotective effect of psoralen in ovariectomy-induced osteoporotic rats via stimulating the osteoblastic differentiation from bone mesenchymal stem cells

Yang, Z., Huang, J.-H., Liu, S.-F., Zhao, Y.-J., Shen, Z.-Y., Wang, Y.-J., & Bian, Q. (2012) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e3182507e18 · Cited by 50

The Science and (Lost) Art of Psoralen Plus UVA Phototherapy

Richard, E. G. (2019) · Dermatologic Clinics · doi:10.1016/j.det.2019.08.002 · Cited by 50

Epidermal Langerhans cells are not required for UV-induced immunosuppression

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Identification of QTLs affecting scopolin and scopoletin biosynthesis in Arabidopsis thaliana

Siwinska, J., Kadziński, L., Banasiuk, R., Gwizdek‐Wiśniewska, A., Olry, A., Banecki, B., Łojkowska, E., & Ihnatowicz, A. (2014) · BMC Plant Biology · doi:10.1186/s12870-014-0280-9 · Cited by 52

The active compounds derived from Psoralea corylifolia for photochemotherapy against psoriasis-like lesions: The relationship between structure and percutaneous absorption

Alalaiwe, A. S., Hung, C., Leu, Y., Tahara, K., Chen, H.-H., Hu, K., & Fang, J. (2018) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2018.08.031 · Cited by 47

Pyrrolo[3,4-h]quinolinones a new class of photochemotherapeutic agents

Barraja, P., Diana, P., Montalbano, A., Carbone, A., Viola, G., Basso, G., Salvador, A., Vedaldi, D., Dall’Acqua, F., & Cirrincione, G. (2011) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2011.02.023 · Cited by 45

Identification and Characterization of Psoralen and Isopsoralen as Potent CYP1A2 Reversible and Time-Dependent Inhibitors in Human and Rat Preclinical Studies

Zhuang, X., Zhong, Y.-H., Xiao, W., Li, H., & Lu, C. (2013) · Drug Metabolism and Disposition · doi:10.1124/dmd.113.053199 · Cited by 43

Effects of Curcuma extract and visible light on adults with plaque psoriasis

Carrión-Gutiérrez, M. A., Ramírez-Boscá, A., Navarro‐López, V., Martínez‐Andrés, A., Asín‐Llorca, M., Bernd, A., & de la Parte, J. F. H. (2015) · European Journal of Dermatology · doi:10.1684/ejd.2015.2584 · Cited by 42

Synthesis of pyrrolo[3,2-h]quinolinones with good photochemotherapeutic activity and no DNA damage

Barraja, P., Caracausi, L., Diana, P., Carbone, A., Montalbano, A., Cirrincione, G., Brun, P., Palù, G., Castagliuolo, I., Dall’Acqua, F., et al. (2010) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2010.04.080 · Cited by 42

Vitamin D Status and Concomitant Autoimmunity in Celiac Disease

Tavakkoli, A., DiGiacomo, D. V., Green, P. H., & Lebwohl, B. (2013) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e318266f81b · Cited by 40

How It Works

Yu, Z., & Wolf, P. (2019) · Dermatologic Clinics · doi:10.1016/j.det.2019.08.004 · Cited by 40

Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function

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An Update on Photodynamic Therapy of Psoriasis—Current Strategies and Nanotechnology as a Future Perspective

Makuch, S., Dróżdż, M., Makarec, A., Ziolkowski, P. P., & Woźniak, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179845 · Cited by 38

In vitro isolation, elicitation of psoralen in callus cultures of Psoralea corylifolia and cloning of psoralen synthase gene

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A Chemical Genetic Screen in Zebrafish for Pathways Interacting with cdx4 in Primitive Hematopoiesis

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Recent advances in phototherapy for psoriasis

Nakamura, M., Farahnik, B., & Bhutani, T. (2016) · F1000Research · doi:10.12688/f1000research.8846.1 · Cited by 34

Repair of DNA interstrand cross‐links during S phase of the mammalian cell cycle

Legerski, R. J. (2010) · Environmental and Molecular Mutagenesis · doi:10.1002/em.20566 · Cited by 35

Furanocoumarins

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Evaluation of chemical phototoxicity, focusing on phosphorylated histone H2AX

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Modulation of expression of IL-8 gene in bronchial epithelial cells by 5-methoxypsoralen

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Phototherapy of Psoriasis, a Chronic Inflammatory Skin Disease

Rácz, E., & Prens, E. P. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-56017-5_24 · Cited by 30

Psoralen, a mechanism-based inactivator of CYP2B6

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Acaricidal activity and sublethal effects of an oxymatrine-based biopesticide on two-spotted spider mite (Acari: Tetranychidae)

Marčić, D., & Međo, I. (2014) · Experimental and Applied Acarology · doi:10.1007/s10493-014-9831-x · Cited by 30

Optimization of elicitation condition with Jasmonic Acid, characterization and antimicrobial activity of Psoralen from direct regenerated plants of Psoralea corylifolia L

Siva, G., Sivakumar, S., Kumar, G. P., Vigneswaran, M., Vinoth, S., Selvan, A. M., Ahamed, A. P., Manivannan, K., Kumar, R. R., Thajuddin, N., et al. (2015) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2015.10.012 · Cited by 30

A Critical Review on Selected External Physical Cues and Modulation of Cell Behavior: Magnetic Nanoparticles, Non-thermal Plasma and Lasers

Smolková, B., Uzhytchak, M., Lynnyk, A., Kubinová, Š., Dejneka, A., & Lunov, O. (2018) · Journal of Functional Biomaterials · doi:10.3390/jfb10010002 · Cited by 30

18β-Glycyrrhetinic acid induces human HaCaT keratinocytes apoptosis through ROS-mediated PI3K-Akt signaling pathway and ameliorates IMQ-induced psoriasis-like skin lesions in mice

Gao, J., Guo, J., Nong, Y., Mo, W., Fang, H., Mi, J., Qi, Q., & Yang, M. (2020) · BMC Pharmacology and Toxicology · doi:10.1186/s40360-020-00419-0 · Cited by 29

Exposure to phototoxic NSAIDs and quinolones is associated with an increased risk of melanoma

Siiskonen, S. J., Koomen, E. R., Visser, L. E., Herings, R. M. C., Guchelaar, H., Stricker, B. H. C., & Nijsten, T. E. C. (2013) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-013-1476-x · Cited by 29

Manipulating the mitochondria activity in human hepatic cell line Huh7 by low-power laser irradiation

Lynnyk, A., Lunová, M., Jirsa, M., Egorova, D., Kulikov, A., Kubinová, Š., Lunov, O., & Dejneka, A. (2018) · Biomedical Optics Express · doi:10.1364/boe.9.001283 · Cited by 28

Repurposing approved therapeutics for new indication: Addressing unmet needs in psoriasis treatment

Jain, H., Bhat, A., Dalvi, H., Godugu, C., Singh, S. B., & Srivastava, S. (2021) · Current Research in Pharmacology and Drug Discovery · doi:10.1016/j.crphar.2021.100041 · Cited by 28

Histone Deacetylase Inhibitor Sodium Butyrate Enhances the Cell Killing Effect of Psoralen plus UVA by Attenuating Nucleotide Excision Repair

Toyooka, T., & Ibuki, Y. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-2546 · Cited by 28

Self-assembled hyaluronic acid nanoparticles for the topical treatment of inflammatory skin diseases: Beyond drug carriers

Lee, W., & Kim, W. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.12.026 · Cited by 27

UV-based therapy and vitamin D

Sage, R. J., & Lim, H. W. (2010) · Dermatologic Therapy · doi:10.1111/j.1529-8019.2009.01292.x · Cited by 24

Primary Mast Cell Disorders in Children

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Ionic Liquid-Based Ultrasonic-Assisted Extraction to Analyze Seven Compounds in Psoralea Fructus Coupled with HPLC

Shi, M., Zhang, J., Liu, C., Cui, Y., Li, C., Liu, Z., & Kang, W. (2019) · Molecules · doi:10.3390/molecules24091699 · Cited by 23

Distinguishing Myth from Fact

Thompson, K. G., & Kim, N. (2019) · Dermatologic Clinics · doi:10.1016/j.det.2019.08.003 · Cited by 23

A Quantitative Mass Spectrometry-Based Approach for Assessing the Repair of 8-Methoxypsoralen-Induced DNA Interstrand Cross-Links and Monoadducts in Mammalian Cells

Liu, S., & Wang, Y. (2013) · Analytical Chemistry · doi:10.1021/ac4012232 · Cited by 21

Identification of Genes Responsive to Solar Simulated UV Radiation in Human Monocyte-Derived Dendritic Cells

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Intake of Furocoumarins and Risk of Skin Cancer in 2 Prospective US Cohort Studies

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Cutaneous sensory nerves: mediators of phototherapeutic effects?

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Transdermal Delivery of Macromolecules Using Nano Lipid Carriers

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Serum concentration of transforming growth factor (TGF)-beta 1 does not predict advanced liver fibrosis in children with chronic hepatitis B.

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A new psoralen derivative with enlarged antiproliferative properties

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Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease

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Drug-free phototherapy of superficial tumors: White light at the end of the tunnel

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Cutaneous Diseases of the External Genitalia

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3-Methyladenine DNA glycosylase is important for cellular resistance to psoralen interstrand cross-links

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Therapeutic Advancements in the Management of Psoriasis: A Clinical Overview and Update

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Insulin‐like growth factor‐1 in psoriatic plaques treated with PUVA and methotrexate

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Bioelectronic devices for light-based diagnostics and therapies

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Ruta graveolens Extracts and Metabolites against Spodoptera frugiperda

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Photosensitization by iodinated DNA minor groove binding ligands: Evaluation of DNA double-strand break induction and repair

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