The DOI matches its Crossref record; 68 of the 68 references it cites were found in a registry or an index.
Acupuncture for Chronic Low Back Pain
Abstract
A 45-year-old man with a 7-year history of low back pain asks his physician for a referral to a licensed acupuncturist. Acupuncture involves the insertion of fine metallic needles into the body at specific sites. Clinical trials of acupuncture for chronic low back pain have shown higher rates of symptom improvement with either acupuncture or sham acupuncture than with usual care.
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In the citing paper
“Positron emission tomography has shown an increase in μ-opioid binding potential in several brain areas. 19”
In the citing paper
“The adverse events may include needle-site pain, nausea, vomiting, light headedness, or fainting.”
In the citing paper
“Functional magnetic resonance imaging has shown prolonged stimulations in the limbic systems and basal forebrain.”
In the citing paper
“Major adverse events related to acupuncture are reported to be rare, with significant adverse events occurring in less than 0.1% of cases. 19”
In the citing paper
“It has been demonstrated that acupuncture induces the release of endogenous opioids in the brain stem, subcortical, and limbic structures, modulating pain perception.”
In the citing paper
“Given various physiological bases and mechanisms for pain modulation, it is likely that acupuncture produces real therapeutic effect.”
Citations
Cites
Epidemiological features of chronic low-back pain
Andersson, G. B. (1999) · The Lancet · doi:10.1016/s0140-6736(99)01312-4 · Cited by 3,181
Human brain mechanisms of pain perception and regulation in health and disease
Apkarian, A. V., Bushnell, M. C., Treede, R., & Zubieta, J. (2005) · European Journal of Pain · doi:10.1016/j.ejpain.2004.11.001 · Cited by 3,126
Chou, R., Qaseem, A., Snow, V., Casey, D., Cross, J. T., Shekelle, P., Owens, D. K., & for the Clinical Efficacy Assessment Subcommittee of the American College of Physicians and the American College of Physicians/American Pain Society Low Back Pain Guidelines Panel* (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-147-7-200710020-00006 · Cited by 2,718
Magnetic Resonance Imaging of the Lumbar Spine in People without Back Pain
Jensen, M. C., Brant-Zawadzki, M. N., Obuchowski, N. A., Modic, M. T., Malkasian, D. R., & Ross, J. S. (1994) · New England Journal of Medicine · doi:10.1056/nejm199407143310201 · Cited by 2,381
Deyo, R. A., & Weinstein, J. N. (2001) · New England Journal of Medicine · doi:10.1056/nejm200102013440508 · Cited by 1,675
Pincus, T., Burton, A. K., Vogel, S., & Field, A. P. (2002) · Spine · doi:10.1097/00007632-200203010-00017 · Cited by 1,633
Chronic back pain is associated with decreased prefrontal and thalamic gray matter density
Apkarian, A. V., Sosa, Y., Sonty, S., Levy, R. M., Harden, R. N., Parrish, T. B., & Gitelman, D. R. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.2541-04.2004 · Cited by 1,434
Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome
Kaptchuk, T. J., Kelley, J. M., Conboy, L. A., Davis, R. B., Kerr, C. E., Jacobson, E. E., Kirsch, I., Schyner, R. N., Nam, B. H., Nguyen, L. T., et al. (2008) · BMJ · doi:10.1136/bmj.39524.439618.25 · Cited by 1,196
Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies
Han, J. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)00006-1 · Cited by 1,088
Chou, R., & Huffman, L. H. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-147-7-200710020-00007 · Cited by 1,045
Research works printed but not linked: 4
- 2001, MMWR Morb Mortal Wkly Rep, 50, 120
- Cherkin DC, 2002, J Am Board Fam Pract, 15, 378
- Chung A, 2003, Can Fam Physician, 49, 985
- Sherman KJ, 2003, Altern Ther Health Med, 9, 54
Cited by
Sorted by citations
RELIEVING PAIN IN AMERICA: A BLUEPRINT FOR TRANSFORMING PREVENTION, CARE, EDUCATION, AND RESEARCH
Simon, L. S. (2012) · Journal of Pain & Palliative Care Pharmacotherapy · doi:10.3109/15360288.2012.678473 · Cited by 2,200
Guidelines for Recognition, Assessment and Treatment of Pain
Mathews, K. A., Kronen, P., Lascelles, B. D. X., Nolan, A. M., Robertson, S. A., Steagall, P. V. M., Wright, B. D., & YAMASHITA, K. (2014) · Journal of Small Animal Practice · doi:10.1111/jsap.12200 · Cited by 380
Chae, Y., Chang, D.-S., Lee, S.-H., Jung, W.-M., Lee, I., Jackson, S. R., Kong, J., Lee, H., Park, H., Lee, H., et al. (2013) · Journal of Pain · doi:10.1016/j.jpain.2012.11.011 · Cited by 200
Publication Trends in Acupuncture Research: A 20-Year Bibliometric Analysis Based on PubMed
Ma, Y., Dong, M., Zhou, K., Mita, C., Liu, J., & Wayne, P. M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0168123 · Cited by 182
Acupuncture for chronic nonspecific low back pain
Mu, J., Furlan, A. D., Lam, W. Y., Hsu, M. Y., Ning, Z., & Lao, L. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013814 · Cited by 169
Metadata
- Authors
- Berman, B. M., Langevin, H. M., Witt, C. M., & Dubner, R.
- Affiliations
- University of Maryland, Baltimore (US)
- Charité – Universitätsmedizin Berlin (DE)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2010-07-29
- Volume
- 363
- Issue
- 5
- Pages
- 454-461
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2152751399
- Cited by
- 273
- References
- 68
- Citations by year
- 2026: 4 · 2025: 14 · 2024: 17 · 2023: 23 · 2022: 25 · 2021: 16 · 2020: 19 · 2019: 15 · 2018: 17 · 2017: 17 · 2016: 12 · 2015: 18 · 2014: 11 · 2013: 20 · 2012: 20
- FWCI
- 4.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Acupuncture Treatment Research Studies
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Myofascial pain diagnosis and treatment
- Keywords
- acupuncture, chronic low back pain, sham acupuncture, acupuncture needles, symptom improvement, usual care comparison
- MeSH terms
- Contraindications, Chronic Disease, Humans, Intervertebral Disc Displacement, Lumbar Vertebrae, Male, Middle Aged, Acupuncture Therapy, Low Back Pain, Practice Guidelines as Topic, Intervertebral Disc Degeneration
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