The DOI matches its Crossref record; 68 of the 68 references it cites were found in a registry or an index.
Acupuncture for Chronic Low Back Pain
Abstract
A 45-year-old man with a 7-year history of low back pain asks his physician for a referral to a licensed acupuncturist. Acupuncture involves the insertion of fine metallic needles into the body at specific sites. Clinical trials of acupuncture for chronic low back pain have shown higher rates of symptom improvement with either acupuncture or sham acupuncture than with usual care.
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In the citing paper
“Positron emission tomography has shown an increase in μ-opioid binding potential in several brain areas. 19”
In the citing paper
“The adverse events may include needle-site pain, nausea, vomiting, light headedness, or fainting.”
In the citing paper
“Functional magnetic resonance imaging has shown prolonged stimulations in the limbic systems and basal forebrain.”
In the citing paper
“Major adverse events related to acupuncture are reported to be rare, with significant adverse events occurring in less than 0.1% of cases. 19”
In the citing paper
“It has been demonstrated that acupuncture induces the release of endogenous opioids in the brain stem, subcortical, and limbic structures, modulating pain perception.”
In the citing paper
“Given various physiological bases and mechanisms for pain modulation, it is likely that acupuncture produces real therapeutic effect.”
Citations
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Metadata
- Authors
- Berman, B. M., Langevin, H. M., Witt, C. M., & Dubner, R.
- Affiliations
- University of Maryland, Baltimore (US)
- Charité – Universitätsmedizin Berlin (DE)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2010-07-29
- Volume
- 363
- Issue
- 5
- Pages
- 454-461
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2152751399
- Cited by
- 273
- References
- 68
- Citations by year
- 2026: 4 · 2025: 14 · 2024: 17 · 2023: 23 · 2022: 25 · 2021: 16 · 2020: 19 · 2019: 15 · 2018: 17 · 2017: 17 · 2016: 12 · 2015: 18 · 2014: 11 · 2013: 20 · 2012: 20
- FWCI
- 4.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Acupuncture Treatment Research Studies
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Myofascial pain diagnosis and treatment
- Keywords
- acupuncture, chronic low back pain, sham acupuncture, acupuncture needles, symptom improvement, usual care comparison
- MeSH terms
- Contraindications, Chronic Disease, Humans, Intervertebral Disc Displacement, Lumbar Vertebrae, Male, Middle Aged, Acupuncture Therapy, Low Back Pain, Practice Guidelines as Topic, Intervertebral Disc Degeneration
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