Calorie and Time Restriction in Weight Loss
Open accessAbstract
Weight loss with calorie restriction is the recommended approach for treatment of obesity, but this approach is resource-intensive and difficult to sustain over time.1 Time-restricted eating is a potentially low-cost and sustainable lifestyle in which daily intake of calories is restricted to a consistent time period of less than 10 hours without explicit attempts to modify diet composition or reduce calories. Chronic disruption of the circadian rhythm increases the risk of obesity and metabolic diseases. Restricting the window of time for eating sustains circadian rhythms and improves metabolism by prolonging the daily fast, which in turn activates cellular pathways that . . .
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Chaix, A., Zarrinpar, A., Miu, P., & Panda, S. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.11.001 · Cited by 956 · see citing works
Wilkinson, M. J., Manoogian, E. N. C., Zadourian, A., Lo, H., Fakhouri, S., Shoghi, A., Wang, X., Fleischer, J. G., Navlakha, S., Panda, S., et al. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2019.11.004 · Cited by 927 · see citing works
Self-citationGill, S., & Panda, S. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.09.005 · Cited by 894 · see citing works
Self-citationCalorie restriction with or without time-restricted eating in weight loss
Liu, D., Huang, Y., Huang, C., Yang, S., Wei, X., Zhang, P., Guo, D., Lin, J., Xu, B., Li, C., et al. (2022) · New England Journal of Medicine · doi:10.1056/nejmoa2114833 · Cited by 516 · see citing works
Treatment of Obesity by Moderate and Severe Caloric Restriction: Results of Clinical Research Trials
Wadden, T. A. (1993) · Annals of Internal Medicine · doi:10.7326/0003-4819-119-7_part_2-199310011-00012 · Cited by 475 · see citing works
Time-restricted eating for the prevention and management of metabolic diseases
Manoogian, E. N. C., Chow, L. S., Taub, P. R., Laferrère, B., & Panda, S. (2022) · Endocrine Reviews · doi:10.1210/endrev/bnab027 · Cited by 344 · see citing works
Self-citationAcosta-Rodríguez, V. A., de Groot, M. H. M., Rijo‐Ferreira, F., Green, C. B., & Takahashi, J. S. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.06.007 · Cited by 252 · see citing works
Phillips, N. E., Mareschal, J., Schwab, N., Manoogian, E. N. C., Borloz, S., Ostinelli, G., Gauthier-Jaques, A., Umwali, S., Rodríguez, E. G., Aeberli, D., et al. (2021) · Nutrients · doi:10.3390/nu13031042 · Cited by 114 · see citing works
Self-citationPRASAD, M. A., Fine, K. S., Gee, A., Nair, N., Popp, C. J., Cheng, B., Manoogian, E. N. C., Panda, S., & Laferrère, B. (2021) · Nutrients · doi:10.3390/nu13072148 · Cited by 48 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Lifestyle Medicine for Obesity in the Era of Highly Effective Anti-Obesity Treatment
Sannidhi, D., Abeles, R., Andrew, W., Bonnet, J. P., Vitale, K., Niranjan, V., Gulati, M., Pauly, K., Moran, R., Alexander, L., et al. (2025) · Nutrients · doi:10.3390/nu17142382 · Cited by 29 · see citing works
“- Low cost and no need for tracking [202].”
- Authors
- Laferrère, B., & Panda, S.
- Affiliations
- Salk Institute for Biological Studies (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2022-04-21
- Volume
- 386
- Issue
- 16
- Pages
- 1572-1573
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC10047152
- OpenAlex
- W4224256710
- Cited by
- 14
- References
- 9
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 3 · 2022: 6
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (R01AG065569)
- Topics
- Health Sciences › Medicine › Physiology › Dietary Effects on Health
- Health Sciences › Medicine › Physiology › Diet and metabolism studies
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Keywords
- time-restricted eating, caloric restriction, weight loss, obesity, circadian rhythm, fasting, metabolic health, sustainable living
- MeSH terms
- Energy Intake, Humans, Weight Loss
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review