The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Noninvasive Detection of Clinically Occult Lymph-Node Metastases in Prostate Cancer
Open accessAbstract
BACKGROUND: Accurate detection of lymph-node metastases in prostate cancer is an essential component of the approach to treatment. We investigated whether highly lymphotropic superparamagnetic nanoparticles, which gain access to lymph nodes by means of interstitial-lymphatic fluid transport, could be used in conjunction with high-resolution magnetic resonance imaging (MRI) to reveal small nodal metastases. METHODS: Eighty patients with presurgical clinical stage T1, T2, or T3 prostate cancer who underwent surgical lymph-node resection or biopsy were enrolled. All patients were examined by MRI before and 24 hours after the intravenous administration of lymphotropic superparamagnetic nanoparticles (2.6 mg of iron per kilogram of body weight). The imaging results were correlated with histopathological findings. RESULTS: Of the 334 lymph nodes that underwent resection or biopsy, 63 (18.9 percent) from 33 patients (41 percent) had histopathologically detected metastases. Of these 63 nodes, 45 (71.4 percent) did not fulfill the usual imaging criteria for malignancy. MRI with lymphotropic superparamagnetic nanoparticles correctly identified all patients with nodal metastases, and a node-by-node analysis had a significantly higher sensitivity than conventional MRI (90.5 percent vs. 35.4 percent, P<0.001) or nomograms. CONCLUSIONS: High-resolution MRI with magnetic nanoparticles allows the detection of small and otherwise undetectable lymph-node metastases in patients with prostate cancer.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Significantly higher sensitivity for lymph node characterization in patients with prostate cancer, in which metastases detection with positron emission tomography (PET) is problematic, could be achieved by using ferumoxtran compared to non-contrast-enhanced MR imaging [160, 161].”
From Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications (2019) · cites this paper as [161]
In the citing paper
“Significantly higher sensitivity for lymph node characterization in patients with prostate cancer, in which metastases detection with positron emission tomography (PET) is problematic, could be achieved by using ferumoxtran compared to non-contrast-enhanced MR imaging [160, 161].”
From Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications (2019) · cites this paper as [160]
In the citing paper
“By using USPIO and contrast-enhanced MRI, micro-metastatic lymph nodes can be distinguished much more efficiently from healthy and inflammatory nodes [161].”
From Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications (2019) · cites this paper as [161]
Citations
Cites
The Measurement of Observer Agreement for Categorical Data
Landis, J. R., & Koch, G. G. (1977) · Biometrics · doi:10.2307/2529310 · Cited by 81,148
Beneficial Effect of Carotid Endarterectomy in Symptomatic Patients with High-Grade Carotid Stenosis
(1991) · New England Journal of Medicine · doi:10.1056/nejm199108153250701 · Cited by 8,368
Stary, H. C., Chandler, A. B., Dinsmore, R. E., Fuster, V., Glagov, S. K., Insull, W., Rosenfeld, M. E., Schwartz, C. J., Wagner, W. D., & Wissler, R. W. (1995) · Circulation · doi:10.1161/01.cir.92.5.1355 · Cited by 3,506
Greenlee, R. T., Hill-Harmon, M. B., Murray, T., & Thun, M. J. (2001) · CA A Cancer Journal for Clinicians · doi:10.3322/canjclin.51.1.15 · Cited by 3,281
Lewin, M., Carlesso, N., Tung, C., Tang, X. S., Cory, D. G., Scadden, D. T., & Weissleder, R. (2000) · Nature Biotechnology · doi:10.1038/74464 · Cited by 1,716
Self-citationROC Methodology in Radiologic Imaging
Metz, C. E. (1986) · Investigative Radiology · doi:10.1097/00004424-198609000-00009 · Cited by 1,628
Bolla, M., González, D., Warde, P. R., Dubois, J. B., Mirimanoff, R., Storme, G. A., Bernier, J., Kuten, A., Sternberg, C. N., Gil, T., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199707313370502 · Cited by 1,547
Messing, E. M., Manola, J. B., Sarosdy, M., Wilding, G., Crawford, E. D., & Trump, D. L. (1999) · New England Journal of Medicine · doi:10.1056/nejm199912093412401 · Cited by 1,178
Magnetic relaxation switches capable of sensing molecular interactions
Pérez, J. M. S., Josephson, L., O'Loughlin, T., Högemann, D., & Weissleder, R. (2002) · Nature Biotechnology · doi:10.1038/nbt720 · Cited by 889
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Items 801–900 of 1,000
Advances and Perspectives in Nanoprobes for Noninvasive Lymph Node Mapping
Li, J., Zhuang, Z., Jiang, B., Zhao, P., & Lin, C. (2015) · Nanomedicine · doi:10.2217/nnm.14.201 · Cited by 36
Superparamagnetic iron oxide-enhanced MRI at 3 T for accurate axillary staging in breast cancer
Motomura, K., Izumi, T., Tateishi, S., Tamaki, Y., Ito, Y., Horinouchi, T., & Nakanishi, K. (2015) · British journal of surgery · doi:10.1002/bjs.10040 · Cited by 36
Theranostic Applications of Stimulus-Responsive Systems based on Fe 2 O 3
Pourmadadi, M., Ahmadi, M. J., Dinani, H. S., Ajalli, N., & Dorkoosh, F. A. (2022) · Pharmaceutical Nanotechnology · doi:10.2174/2211738510666220210105113 · Cited by 36
Huang, R., Zhou, X., Chen, G., Su, L., Liu, Z., Zhou, P., Weng, J., & Min, Y. (2022) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1800 · Cited by 38
Elucidating Structure and FunctionIn VivoWith Hybrid Fluorescence and Magnetic Resonance Imaging
Niedre, M. J., & Ntziachristos, V. (2008) · Proceedings of the IEEE · doi:10.1109/jproc.2007.913498 · Cited by 36
Simple Synthesis and Functionalization of Iron Nanoparticles for Magnetic Resonance Imaging
Cheong, S., Ferguson, P. M., Feindel, K. W., Hermans, I. F., Callaghan, P. T., Meyer, C., Slocombe, A., Su, C., Cheng, F., Yeh, C., et al. (2011) · Angewandte Chemie · doi:10.1002/ange.201100562 · Cited by 36
Magnetic resonance and fluorescence based molecular imaging technologies
Sosnovik, D. E., & Weissleder, R. (2005) · Birkhäuser Basel eBooks · doi:10.1007/3-7643-7426-8_3 · Cited by 36
Self-citationImpact of Stroma on the Growth, Microcirculation, Metabolism of Experimental Prostate Tumors
Zechmann, C. M., Woenne, E. C., Brix, G., Radzwill, N., Ilg, M., Bachert, P., Peschke, P., Kirsch, S., Kauczor, H., Delorme, S., et al. (2007) · Neoplasia · doi:10.1593/neo.06688 · Cited by 36
The potential legacy of cancer nanotechnology: cellular selection
Patra, H. K., & Turner, A. P. F. (2013) · Trends in biotechnology · doi:10.1016/j.tibtech.2013.10.004 · Cited by 35
Pelvic node dissection in prostate cancer: extended, limited, or not at all?
Hyndman, M. E., Mullins, J. K., & Pavlovich, C. P. (2010) · Current Opinion in Urology · doi:10.1097/mou.0b013e328338405d · Cited by 35
Fuchsjäger, M., Shukla‐Dave, A., Hricak, H., Wang, L., Touijer, K. A., Donohue, J. F., Eastham, J. A., & Kattan, M. W. (2009) · British Journal of Urology · doi:10.1111/j.1464-410x.2009.08406.x · Cited by 35
Diffusion-weighted imaging (DWI) in lymph node staging for prostate cancer
Caglič, I., & Barrett, T. (2018) · Translational Andrology and Urology · doi:10.21037/tau.2018.08.04 · Cited by 35
The Role of Magnetic Resonance Imaging in (Future) Cancer Staging
Scheenen, T. W. J., & Zámecnik, P. (2020) · Investigative Radiology · doi:10.1097/rli.0000000000000741 · Cited by 35
Lymphotropic nanoparticle enhanced MRI for the staging of genitourinary tumors
Mouli, S. K., Zhao, L. C., Omary, R. A., & Thaxton, C. S. (2010) · Nature Reviews Urology · doi:10.1038/nrurol.2009.254 · Cited by 35
Next Generation Radiologic-Pathologic Correlation in Oncology: Rad-Path 2.0
Kuo, M., & Yamamoto, S. (2011) · American Journal of Roentgenology · doi:10.2214/ajr.11.7163 · Cited by 35
Gros, S. J., Dohrmann, T., Peldschus, K., Schurr, P. G., Kaifi, J. T., Kalinina, T., Reichelt, U., Mann, O., Strate, T. G., Adam, G., et al. (2009) · International Journal of Cancer · doi:10.1002/ijc.24980 · Cited by 35
Stamopoulos, D., Manios, E., Gogola, V., Benaki, D. C., Bouziotis, P., Niarchos, D., & Pissas, M. (2008) · Nanotechnology · doi:10.1088/0957-4484/19/50/505101 · Cited by 35
Lymphotrophic nanoparticle enhanced MR imaging (LNMRI) for lymph node imaging
Saokar, A., Braschi, M., & Harisinghani, M. G. (2006) · Abdominal Imaging · doi:10.1007/s00261-006-9006-2 · Cited by 35
Self-citationPresent and future of metal nanoparticles in tumor ablation therapy
Lou, W., Xie, L., Xu, L., Xu, M., Xu, F., Zhao, Q., & Jiang, T. (2023) · Nanoscale · doi:10.1039/d3nr04362b · Cited by 33
Local staging of prostate cancer with MRI
Soylu, F. N., Eggener, S. E., & Oto, A. (2011) · Diagnostic and Interventional Radiology · doi:10.4261/1305-3825.dir.4970-11.2 · Cited by 34
Muehe, A. M., Siedek, F., Theruvath, A. J., Seekins, J. M., Spunt, S. L., Pribnow, A. K., Hazard, F. K., Liang, T., & Daldrup-Link, H. E. (2020) · Theranostics · doi:10.7150/thno.40606 · Cited by 34
Wondergem, M., van der Zant, F. M., Broos, W. A. M., Roeleveld, T. A., Donker, R., ten Oever, D., Geenen, R. W. F., & Knol, R. J. J. (2020) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-020-04782-2 · Cited by 34
The role of lymphadenectomy in prostate cancer
Burkhard, F. C., Schumacher, M. C., & Studer, U. E. (2005) · Nature Clinical Practice Urology · doi:10.1038/ncpuro0245 · Cited by 34
Non-invasive molecular imaging of prostate cancer lymph node metastasis
Pouliot, F., Johnson, M., & Wu, L. (2009) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2009.04.004 · Cited by 34
Metastatic lymph nodes in hilar cholangiocarcinoma: does size matter?
Ruys, A. T., ten Kate, F. J. W., Busch, O. R., Engelbrecht, M. R. W., Gouma, D. J., & van Gulik, T. M. (2011) · HPB · doi:10.1111/j.1477-2574.2011.00389.x · Cited by 34
Image-guided robotic interventions for prostate cancer
Sridhar, A. N., Hughes‐Hallett, A., Mayer, E. K., Pratt, P., Edwards, P., Yang, G., Darzi, A. W., & Vale, J. (2013) · Nature Reviews Urology · doi:10.1038/nrurol.2013.129 · Cited by 34
Nanomedical Innovation: the SEON-concept for an Improved Cancer Therapy with Magnetic Nanoparticles
Lyer, S., Tietze, R., Unterweger, H., Zaloga, J., Singh, R., Matuszak, J., Poettler, M., Friedrich, R. P., Duerr, S., Cicha, I., et al. (2015) · Nanomedicine · doi:10.2217/nnm.15.159 · Cited by 34
Magnetic nanoformulations for prostate cancer
Chowdhury, P., Roberts, A. M., Khan, S., Hafeez, B. B., Chauhan, S. C., Jaggi, M., & Yallapu, M. M. (2017) · Drug Discovery Today · doi:10.1016/j.drudis.2017.04.018 · Cited by 34
Kim, H., Park, Y., Stevens, M. M., Kwon, W., & Hahn, S. K. (2019) · Journal of Controlled Release · doi:10.1016/j.jconrel.2019.04.003 · Cited by 35
Speight, J. L., & Roach, M. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2006.10.3218 · Cited by 34
Role of Pelvic Lymph Node Dissection in Prostate Cancer Treatment
Joung, J. Y., Cho, I., & Lee, K. H. (2011) · Korean journal of urology · doi:10.4111/kju.2011.52.7.437 · Cited by 33
Molecular and Functional Imaging for Detection of Lymph Node Metastases in Prostate Cancer
Fortuin, A. S., de Rooij, M., Zámecnik, P., Haberkorn, U., & Barentsz, J. O. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140713842 · Cited by 33
Self-citationGallo, J., Garcı́a, I., Genicio, N., Padró, D., & Penadés, S. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.09.010 · Cited by 33
Cell tracking in cardiac repair: what to image and how to image
Ruggiero, A., Thorek, D. L. J., Guenoun, J., Krestin, G. P., & Bernsen, M. R. (2011) · European Radiology · doi:10.1007/s00330-011-2190-7 · Cited by 33
John, R., Adie, S. G., Chaney, E. J., Marjanović, M., Tangella, K. V., & Boppart, S. A. (2012) · Annals of Surgical Oncology · doi:10.1245/s10434-012-2434-z · Cited by 33
Lymphatic Vessel on a Chip with Capability for Exposure to Cyclic Fluidic Flow
Fathi, P., Holland, G. E., Pan, D., & Esch, M. B. (2020) · ACS Applied Bio Materials · doi:10.1021/acsabm.0c00609 · Cited by 33
Magnetic nanomaterials-mediated cancer diagnosis and therapy
Liu, X., Zhang, H., Zhang, T., Wang, Y., Jiao, W., Lu, X., Gao, X., Xie, M., Shan, Q., Wen, N., et al. (2021) · Progress in Biomedical Engineering · doi:10.1088/2516-1091/ac3111 · Cited by 34
Kim, D., Chae, M. K., Joo, H. J., Jeong, I.-H., Cho, J., & Lee, C. (2012) · Langmuir · doi:10.1021/la300043m · Cited by 33
The role of whole pelvic radiotherapy in locally advanced prostate cancer
Dirix, P. R., Haustermans, K. M., Junius, S., Withers, R. H., Oyen, R., & Poppel, H. V. (2006) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2006.03.011 · Cited by 33
Zheng, S., Huang, M., Hong, R., Deng, S., Cheng, L., Gao, B., & Badami, D. (2013) · Journal of Biomaterials Applications · doi:10.1177/0885328213493486 · Cited by 33
New imaging modalities in bladder cancer
Saksena, M. A., Dahl, D. M., & Harisinghani, M. G. (2006) · World Journal of Urology · doi:10.1007/s00345-006-0118-7 · Cited by 33
Self-citationAdvances in contrast media research1
Mattrey, R. F., & Aguirre, D. A. (2003) · Academic Radiology · doi:10.1016/s1076-6332(03)00642-1 · Cited by 33
Update on positron emission tomography for imaging of prostate cancer
Kitajima, K., Murphy, R. C., Nathan, M. A., & Sugimura, K. (2013) · International Journal of Urology · doi:10.1111/iju.12250 · Cited by 32
Farid, R. M., Gaafar, P. M. E., Hazzah, H. A., Helmy, M. W., & Abdallah, O. Y. (2020) · Nanomedicine · doi:10.2217/nnm-2019-0428 · Cited by 32
Magnetic Gold Nanoparticles with Idealized Coating for Enhanced Point‐Of‐Care Sensing
Gessner, I., Park, J., Lin, H.-Y., Lee, H., & Weissleder, R. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202102035 · Cited by 32
Self-citationLi, M., Zheng, X., Han, T., Ma, S., Wang, Y., Sun, B., Xu, J., Wang, X., Zhang, S., Zhu, S., et al. (2022) · Theranostics · doi:10.7150/thno.78085 · Cited by 32
The role of imaging in staging and monitoring testicular cancer
Brunereau, L., Bruyère, F., Linassier, C., & Baulieu, J. (2012) · Diagnostic and Interventional Imaging · doi:10.1016/j.diii.2012.01.014 · Cited by 32
Gene expression and gene therapy imaging
Rome, C., Couillaud, F., & MOONEN, C. T. W. (2006) · European Radiology · doi:10.1007/s00330-006-0378-z · Cited by 32
Meijer, H. J. M., van Lin, E. N., Debats, O. A., Witjes, J. A., Span, P. N., Kaanders, J. H. A. M., & Barentsz, J. O. (2011) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2011.04.054 · Cited by 32
Self-citationModalities for Imaging of Prostate Cancer
Hou, A. H., Swanson, D. A., & Barqawi, A. B. (2009) · Advances in Urology · doi:10.1155/2009/818065 · Cited by 32
Choi, S. H., Han, M. H., Moon, W. K., Son, K. R., Won, J., Kim, J., Kwon, B. J., Na, D. G., Weinmann, H.-J., & Chang, K. H. (2006) · Radiology · doi:10.1148/radiol.2413051979 · Cited by 32
Update on magnetic resonance imaging, ProstaScint, and novel imaging in prostate cancer*
Brassell, S. A., Rosner, I. L., & McLeod, D. G. (2005) · Current Opinion in Urology · doi:10.1097/01.mou.0000165549.94663.2d · Cited by 32
Recapitulating the Tumor Ecosystem Along the Metastatic Cascade Using 3D Culture Models
Kim, J., & Tanner, K. (2015) · Frontiers in Oncology · doi:10.3389/fonc.2015.00170 · Cited by 31
Inorganic nanobiomaterial drug carriers for medicine
Singh, R. K., & Kim, H. (2013) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-013-1092-y · Cited by 31
Diagnosis of prostate cancer via nanotechnological approach
Lee, K. H., Kang, B. J., Jeun, M., Jang, G. H., Song, S. H., Jeong, I. G., Kim, C., & Searson, P. C. (2015) · International Journal of Nanomedicine · doi:10.2147/ijn.s91908 · Cited by 31
Cheng, L., Kamkaew, A., Shen, S., Valdovinos, H. F., Sun, H., Hernandez, R. T., Goel, S., Liu, T., Thompson, C. R., Barnhart, T. E., et al. (2016) · Small · doi:10.1002/smll.201601696 · Cited by 31
Sekiyama, S., Umezawa, M., Iizumi, Y., Ube, T., Okazaki, T., Kamimura, M., & Soga, K. (2018) · Langmuir · doi:10.1021/acs.langmuir.8b03789 · Cited by 31
New approaches for effective and safe pelvic radiotherapy in high-risk prostate cancer
Tharmalingam, H., Choudhury, A., van Herk, M., McWilliam, A., & Hoskin, P. (2019) · Nature Reviews Urology · doi:10.1038/s41585-019-0213-3 · Cited by 31
Park, S. Y., Oh, Y. T., Jung, D. C., Cho, N. H., Choi, Y. D., & Rha, K. H. (2015) · American Journal of Roentgenology · doi:10.2214/ajr.14.14138 · Cited by 31
Hedgire, S., Pargaonkar, V., Elmi, A., Harisinghani, A. M., & Harisinghani, M. G. (2012) · Radiologic Clinics of North America · doi:10.1016/j.rcl.2012.08.002 · Cited by 31
Self-citationRole of routine 16b1 lymph node biopsy in the management of gallbladder cancer: an analysis
Agarwal, A., Kalayarasan, R., Javed, A., & Sakhuja, P. (2013) · HPB · doi:10.1111/hpb.12127 · Cited by 31
Choi, S. H., Cho, H. R., Kim, H. S., Kim, Y. H., Kang, K. W., Kim, H., & Moon, W. K. (2011) · NMR in Biomedicine · doi:10.1002/nbm.1788 · Cited by 31
Naito, S. (2005) · Japanese Journal of Clinical Oncology · doi:10.1093/jjco/hyi113 · Cited by 31
Li, Y., Humphries, B. A., Wang, Z., Lang, S., Huang, X., Xiao, H., Jiang, Y., & Yang, C. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b10306 · Cited by 31
Molecular imaging in prostate cancer
Karam, J. A., Mason, R. P., Koeneman, K. S., Antich, P. P., Benaim, E. A., & Hsieh, J. (2003) · Journal of Cellular Biochemistry · doi:10.1002/jcb.10636 · Cited by 31
Role of Pelvic Lymphadenectomy in Prostate Cancer Management
Sivalingam, S., Oxley, J., Probert, J. L., Stolzenburg, J. ‐., & Schwaibold, H. E. (2007) · Urology · doi:10.1016/j.urology.2006.10.031 · Cited by 31
Murat, F. J., & Gelet, A. (2008) · Current Urology Reports · doi:10.1007/s11934-008-0022-3 · Cited by 31
Newer Imaging Modalities to Assess Tumor in the Prostate
Hersh, M. R., Knapp, E. L., & Choi, J. (2004) · Cancer Control · doi:10.1177/107327480401100602 · Cited by 31
A urologist’s perspective on prostate cancer imaging: past, present, and future
George, A. K., Turkbey, B., Valayil, S. G., Muthigi, A., Mertan, F., Kongnyuy, M., & Pinto, P. A. (2016) · Abdominal Radiology · doi:10.1007/s00261-016-0751-6 · Cited by 30
Global regulations and legislations on nanoparticles usage and application in diverse horizons
Mishra, A. K., Das, R., Sahoo, S., & Biswal, B. (2022) · Comprehensive analytical chemistry · doi:10.1016/bs.coac.2021.12.004 · Cited by 30
PET in Prostate and Bladder Tumors
Lee, S. T., Lawrentschuk, N., & Scott, A. M. (2012) · Seminars in Nuclear Medicine · doi:10.1053/j.semnuclmed.2012.03.002 · Cited by 30
Cream Formulation Impact on Topical Administration of Engineered Colloidal Nanoparticles
Santini, B., Zanoni, I., Marzi, R., Cigni, C., Bedoni, M., Gramatica, F., Palugan, L., Corsi, F., Granucci, F., & Colombo, M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0126366 · Cited by 30
Neuroinflammatory Imaging Biomarkers: Relevance to Multiple Sclerosis and its Therapy
Tourdias, T., & Dousset, V. (2012) · Neurotherapeutics · doi:10.1007/s13311-012-0155-4 · Cited by 32
Haun, J. B., Yoon, T., Lee, H., & Weissleder, R. (2011) · Methods in molecular biology · doi:10.1007/978-1-61779-052-2_3 · Cited by 30
Self-citationNanobiosensors: Role in Cancer Detection and Diagnosis
Gdowski, A., Ranjan, A. P., Mukerjee, A., & Vishwanatha, J. K. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-81-322-1777-0_4 · Cited by 30
Contrast-Enhanced MR Imaging of Lymph Nodes in Cancer Patients
Choi, S. H., & Moon, W. K. (2010) · Korean Journal of Radiology · doi:10.3348/kjr.2010.11.4.383 · Cited by 30
Vu-Quang, H., Muthiah, M., Kim, Y.-K., Cho, C., Namgung, R., Kim, W. J., Rhee, J. H., Kang, S. H., Jun, S. Y., Choi, Y., et al. (2012) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2012.01.067 · Cited by 33
Bayley, A., Rosewall, T., Craig, T., Bristow, R. G., Chung, P. W. M., Gospodarowicz, M. K., Ménard, C. M., Milosevic, M., Warde, P. R., & Catton, C. (2009) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2009.05.006 · Cited by 30
Pelvic Lymph Node Dissection in Prostate Cancer: Indications, Extent and Tailored Approaches
Bianchi, L., Gandaglia, G., Fossati, N., Suardi, N. R., Moschini, M., Cucchiara, V., Bianchi, M., Damiano, R., Schiavina, R., Shariat, S. F., et al. (2015) · Urologia Journal · doi:10.5301/uro.5000139 · Cited by 30
Okamura, H., Pisani, L. J., Dalal, A. R., Emrich, F. C., Dake, B. A., Arakawa, M., Onthank, D. C., Cesati, R. R. I., Robinson, S. P., Milanesi, M., et al. (2014) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.114.001658 · Cited by 30
The role of lymphadenectomy in high risk prostate cancer
Burkhard, F. C., & Studer, U. E. (2008) · World Journal of Urology · doi:10.1007/s00345-008-0251-6 · Cited by 30
Tang, L., Yang, X., Dobrucki, L. W., Chaudhury, I., Yin, Q., Yao, C., Lezmi, S., Helferich, W. G., Fan, T. M., & Cheng, J. (2012) · Angewandte Chemie · doi:10.1002/ange.201205271 · Cited by 30
Molecular imaging of tumor invasion and metastases: the role of MRI
McCann, T. E., Kosaka, N., Türkbey, B., Mitsunaga, M., Choyke, P. L., & Kobayashi, H. (2010) · NMR in Biomedicine · doi:10.1002/nbm.1590 · Cited by 29
McDermott, S., Thayer, S. P., Castillo, C. F.-D., Mino-Kenudson, M. A., Weissleder, R., & Harisinghani, M. G. (2013) · Translational Oncology · doi:10.1593/tlo.13400 · Cited by 29
Self-citationImaging of apoptosis in the heart with nanoparticle technology
Chen, H. H., Josephson, L., & Sosnovik, D. E. (2010) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.115 · Cited by 29
The potential of nanoparticle-enhanced imaging
Feldman, A. S., McDougal, W. S., & Harisinghani, M. G. (2008) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2007.03.016 · Cited by 29
Self-citationSynthesis of ligand-functionalized water-soluble [18F]YF3 nanoparticles for PET imaging
Xiong, L., Shen, B., Behera, D., Gambhir, S. S., Chin, F. T., & Rao, J. (2013) · Nanoscale · doi:10.1039/c3nr00335c · Cited by 29
Touijer, K. A., Ahallal, Y., & Guillonneau, B. D. (2012) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2012.04.021 · Cited by 29
In Vivo Imaging of the Aneurysm Wall With MRI and a Macrophage-Specific Contrast Agent
Truijers, M., Fütterer, J. J., Takahashi, S., Heesakkers, R. A. M., Blankensteijn, J. D., & Barentsz, J. O. (2009) · American Journal of Roentgenology · doi:10.2214/ajr.09.2619 · Cited by 29
Self-citationSee the unseen: Mesorectal lymph node metastases in prostate cancer
Hijazi, S., Meller, B., Leitsmann, C., Strauß, A., Ritter, C. O., Lotz, J., Meller, J., Trojan, L., & Sahlmann, C. (2016) · The Prostate · doi:10.1002/pros.23168 · Cited by 29
Tang, Y., Liu, Y., Li, W., Xie, Y., Li, Y., Wu, J., Wang, S., Tian, Y., Tian, W., Teng, Z., et al. (2016) · RSC Advances · doi:10.1039/c6ra09344b · Cited by 29
Wang, S., Cao, Y., Zhang, Q., Peng, H., Liang, L., Li, Q., Shen, S., Tuerdi, A., Xu, Y., Cai, S., et al. (2017) · ACS Omega · doi:10.1021/acsomega.7b00993 · Cited by 29
Czarniecki, M., Pesapane, F., Wood, B. J., Choyke, P. L., & Türkbey, B. (2018) · Translational Andrology and Urology · doi:10.21037/tau.2018.05.15 · Cited by 29
Godlewski, M. M., Kaszewski, J., Kiełbik, P., Olszewski, J., Lipiński, W., Słońska, A., Rosowska, J., Witkowski, B. S., Gralak, M. A., Gajewski, Z., et al. (2020) · Nanotechnology Reviews · doi:10.1515/ntrev-2020-0022 · Cited by 30
Cleary, J. O., & Guimarães, A. R. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-386456-7.07609-7 · Cited by 34
Saksena, M. A., Harisinghani, M. G., Hahn, P. F., Kim, J., Saokar, A., King, B., & Weissleder, R. (2006) · American Journal of Roentgenology · doi:10.2214/ajr.05.0873 · Cited by 29
Self-citationHeijmink, S. W. T. P. J., Scheenen, T. W. J., tterer, J. J. F., Klomp, D. W. J., Heesakkers, R. A. M., de Kaa, C. A. H., van Lin, E. N. J. T., Heerschap, A., & Barentsz, J. O. (2007) · Investigative Radiology · doi:10.1097/01.rli.0000262759.46364.50 · Cited by 29
Self-citationPearls and Pitfalls of MR Lymphography in Gynecologic Malignancy
Narayanan, P., Iyngkaran, T., Sohaib, S. A., Reznek, R. H., & Rockall, A. (2009) · Radiographics · doi:10.1148/rg.294085231 · Cited by 29
Problems and prospects of modern lymph node imaging
Wunderbaldinger, P. (2006) · European Journal of Radiology · doi:10.1016/j.ejrad.2005.12.037 · Cited by 29
Muthiah, M., Vu-Quang, H., Kim, Y.-K., Rhee, J. H., Kang, S. H., Jun, S. Y., Choi, Y., Jeong, Y. Y., Cho, C., & Park, I. (2012) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2012.11.011 · Cited by 28
Metadata
- Authors
- Harisinghani, M. G., Barentsz, J., Hahn, P. F., Deserno, W. M., Tabatabaei, S., van de Kaa, C. H., de la Rosette, J., & Weissleder, R.
- Affiliations
- Harvard University (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2003-06-19
- Volume
- 348
- Issue
- 25
- Pages
- 2491-2499
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2116810900
- Cited by
- 1,971
- References
- 42
- Citations by year
- 2026: 13 · 2025: 15 · 2024: 34 · 2023: 42 · 2022: 54 · 2021: 49 · 2020: 59 · 2019: 50 · 2018: 66 · 2017: 82 · 2016: 83 · 2015: 94 · 2014: 95 · 2013: 120 · 2012: 129
- FWCI
- 81.09
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- Funders
- National Institutes of Health (5r01ca059649-07)
- National Cancer Institute (R01-CA59649)
- Topics
- Health Sciences › Medicine › Urology › Prostate Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › MRI in cancer diagnosis
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Medical Imaging Techniques and Applications
- Keywords
- prostate cancer, lymph node metastasis, superparamagnetic iron oxide nanoparticles, magnetic resonance imaging, non-invasive detection, lymphatic drainage, diagnostic sensitivity
- MeSH terms
- Aged, Biopsy, Contrast Media, Ferric Compounds, Humans, Image Processing, Computer-Assisted, Lymph Nodes, Lymphatic Metastasis, Magnetic Resonance Imaging, Magnetics, Male, Middle Aged, Neoplasm Staging, Particle Size, Prospective Studies, Prostatic Neoplasms, Sensitivity and Specificity, Nanotechnology
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
