The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Sirolimus-Eluting and Paclitaxel-Eluting Stents for Coronary Revascularization
Abstract
BACKGROUND: Sirolimus-eluting stents and paclitaxel-eluting stents, as compared with bare-metal stents, reduce the risk of restenosis. It is unclear whether there are differences in safety and efficacy between the two types of drug-eluting stents. METHODS: We conducted a randomized, controlled, single-blind trial comparing sirolimus-eluting stents with paclitaxel-eluting stents in 1012 patients undergoing percutaneous coronary intervention. The primary end point was a composite of major adverse cardiac events (death from cardiac causes, myocardial infarction, and ischemia-driven revascularization of the target lesion) by nine months. Follow-up angiography was completed in 540 of 1012 patients (53.4 percent). RESULTS: The two groups had similar baseline clinical and angiographic characteristics. The rate of major adverse cardiac events at nine months was 6.2 percent in the sirolimus-stent group and 10.8 percent in the paclitaxel-stent group (hazard ratio, 0.56; 95 percent confidence interval, 0.36 to 0.86; P=0.009). The difference was driven by a lower rate of target-lesion revascularization in the sirolimus-stent group than in the paclitaxel-stent group (4.8 percent vs. 8.3 percent; hazard ratio, 0.56; 95 percent confidence interval, 0.34 to 0.93; P=0.03). Rates of death from cardiac causes were 0.6 percent in the sirolimus-stent group and 1.6 percent in the paclitaxel-stent group (P=0.15); the rates of myocardial infarction were 2.8 percent and 3.5 percent, respectively (P=0.49); and the rates of angiographic restenosis were 6.6 percent and 11.7 percent, respectively (P=0.02). CONCLUSIONS: As compared with paclitaxel-eluting stents, the use of sirolimus-eluting stents results in fewer major adverse cardiac events, primarily by decreasing the rates of clinical and angiographic restenosis.
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Serruys, P. W., de Jaegere, P., Kiemeneij, F., Macaya, C., Rutsch, W., Heyndrickx, G., Emanuelsson, H., Marco, J., Legrand, V., Materne, P., et al. (1994) · New England Journal of Medicine · doi:10.1056/nejm199408253310801 · Cited by 4,556
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Moses, J. W., Leon, M. B., Popma, J. J., Fitzgerald, P. J., Holmes, D. R., O'Shaughnessy, C., Caputo, R. P., Kereiakes, D. J., Williams, D. O., Teirstein, P. S., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa035071 · Cited by 4,224
Morice, M.-C., Serruys, P. W., Sousa, J. E., Fajadet, J., Ban Hayashi, E., Perin, M., Colombo, A., Schuler, G., Barragan, P., Guagliumi, G., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012843 · Cited by 4,033
Assessing the quality of controlled clinical trials
Jüni, P., Altman, D. G., & Egger, M. (2001) · BMJ · doi:10.1136/bmj.323.7303.42 · Cited by 3,309
Self-citationA Polymer-Based, Paclitaxel-Eluting Stent in Patients with Coronary Artery Disease
Stone, G. W., Ellis, S. G., Cox, D. A., Hermiller, J., O'Shaughnessy, C., Mann, J. T., Turco, M., Caputo, R., Bergin, P., Greenberg, J., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032441 · Cited by 2,749
Intravascular Stents to Prevent Occlusion and Re-Stenosis after Transluminal Angioplasty
Sigwart, U., Puel, J., Mirkovitch, V., Joffre, F., & Kappenberger, L. (1987) · New England Journal of Medicine · doi:10.1056/nejm198703193161201 · Cited by 1,892
Colombo, A., Drzewiecki, J., Banning, A., Grube, E., Hauptmann, K., Silber, S., Dudek, D., Fort, S., Schiele, F., Zmudka, K., et al. (2003) · Circulation · doi:10.1161/01.cir.0000086926.62288.a6 · Cited by 1,016
Schofer, J., Schlüter, M., Gershlick, A. H., Wijns, W., Garcia, E., Schampaert, E., & Breithardt, G. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14462-5 · Cited by 955
Grube, E., Silber, S., Hauptmann, K. E., Mueller, R., Buellesfeld, L., Gerckens, U., & Russell, M. E. (2003) · Circulation · doi:10.1161/01.cir.0000047700.58683.a1 · Cited by 865
Cited by
Daemen, J., Wenaweser, P., Tsuchida, K., Abrecht, L., Vaina, S., Morger, C., Kukreja, N., Jüni, P., Sianos, G., Hellige, G., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60314-6 · Cited by 1,757
Self-citationJagur‐Grodzinski, J. (2006) · Polymers for Advanced Technologies · doi:10.1002/pat.729 · Cited by 394
Ribichini, F., Tomai, F., De Luca, G., Boccuzzi, G., Presbitero, P., Pesarini, G., Ferrero, V., Ghini, A. S., Abukaresh, R., Aurigemma, C., et al. (2011) · The American Journal of Medicine · doi:10.1016/j.amjmed.2010.11.027 · Cited by 31
Metadata
- Authors
- Windecker, S., Remondino, A., Eberli, F. R., Jüni, P., Räber, L., Wenaweser, P., Togni, M., Billinger, M., Tüller, D., Seiler, C., Roffi, M., Corti, R., Sütsch, G., Maier, W., Lüscher, T., Hess, O. M., Egger, M., & Meier, B.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2005-08-18
- Volume
- 353
- Issue
- 7
- Pages
- 653-662
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1997207240
- Cited by
- 593
- References
- 19
- FWCI
- 76.77
- Type
- journal article
- Language
- en
- Open access
- closed
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- Windecker, S., Remondino, A., Eberli, F. R., Jüni, P., Räber, L., Wenaweser, P., Togni, M., Billinger, M., Tüller, D., Seiler, C., Roffi, M., Corti, R., Sütsch, G., Maier, W., Lüscher, T., Hess, O. M., Egger, M., & Meier, B. (2005). Sirolimus-Eluting and Paclitaxel-Eluting Stents for Coronary Revascularization. New England Journal of Medicine. https://doi.org/10.1056/nejmoa051175
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
