Complement C3 Variant and the Risk of Age-Related Macular Degeneration
Yates, John R.W., Sepp, Tiina, Matharu, Baljinder K., Khan, Jane C., Thurlby, Deborah A., Shahid, Humma, Clayton, David G., Hayward, Caroline, Morgan, Joanne, Wright, Alan F., Armbrecht, Ana Maria, Dhillon, Baljean, Deary, Ian J., Redmond, Elizabeth, Bird, Alan C., Moore, Anthony T.·2007·New England Journal of Medicine
Cited by (834)
Items 101–200 of 834
- C3 R102G polymorphism increases risk of age-related macular degenerationKylee L. Spencer, Lana M. Olson, Bernard M. Anderson, Nathalie C. Schnetz‐Boutaud, William K. Scott, Paul J. Gallins, A. Agarwal, Eric A. Postel, Margaret Ann Pericak‐Vance, Jonathan L. Haines · 2008 · Human Molecular Genetics
- The complement cascade as a therapeutic target in intracerebral hemorrhageAndrew F. Ducruet, Brad E. Zacharia, Zachary L. Hickman, Bartosz T. Grobelny, Mason L. Yeh, Sergey A. Sosunov, Edward Sander Connolly · 2009 · Experimental Neurology
- Age-related macular degeneration and the role of the complement systemSelina McHarg, Simon J. Clark, Anthony J. Day, Paul N. Bishop · 2015 · Molecular Immunology
- Complement in therapy and diseaseJoost P.M. Melis, Kristin Strumane, Sigrid R. Ruuls, Frank J M Beurskens, Janine Schuurman, Paul W.H.I. Parren · 2015 · Molecular Immunology
- Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual lossPeter J. Francis, Sara Hamon, Jürg Ott, Richard G. Weleber, Michael L. Klein · 2008 · Journal of Medical Genetics
- Elevated membrane attack complex in human choroid with high risk complement factor H genotypesRobert F. Mullins, Aaron D. Dewald, Luan M. Streb, Kai Wang, Markus H. Kuehn, Edwin M. Stone · 2011 · Experimental Eye Research
- Genetic variants in the complement system predisposing to age-related macular degeneration: A reviewElizabeth C. Schramm, Simon J. Clark, Michael P. Triebwasser, Soumya Raychaudhuri, Johanna M. Seddon, John P. Atkinson · 2014 · Molecular Immunology
- Prospective Assessment of Genetic Effects on Progression to Different Stages of Age-Related Macular Degeneration Using Multistate Markov ModelsYi Yu, Robyn C Reynolds, BERNARD A. ROSNER, Mark J. Daly, Johanna M. Seddon · 2012 · Investigative Ophthalmology & Visual Science
- Association of Variants in the LIPC and ABCA1 Genes with Intermediate and Large Drusen and Advanced Age-Related Macular DegenerationYi Yu, Robyn C Reynolds, Jesen A. Fagerness, BERNARD A. ROSNER, Mark J. Daly, Johanna M. Seddon · 2011 · Investigative Ophthalmology & Visual Science
- Elevated High-Density Lipoprotein Cholesterol and Age-Related Macular Degeneration: The Alienor StudyAudrey Cougnard‐Grégoire, Marie‐Noëlle Delyfer, Jean‐François Korobelnik, Marie‐Bénédicte Rougier, Mélanie Le Goff, Jean‐François Dartigues, Pascale Barberger‐Gateau, Cécile Delcourt · 2014 · PLoS ONE
- Infiltration of Proinflammatory M1 Macrophages into the Outer Retina Precedes Damage in a Mouse Model of Age-Related Macular DegenerationFernando Cruz‐Guilloty, Ali M. Saeed, Jose J. Echegaray, Stéphanie Duffort, Asha Ballmick, Yaohong Tan, Michel Betancourt, Eduardo J. Viteri, Ghansham C. Ramkhellawan, E. J. Ewald et al. · 2013 · International Journal of Inflammation
- Smoking, Dietary Betaine, Methionine, and Vitamin D in Monozygotic Twins with Discordant Macular Degeneration: Epigenetic ImplicationsJohanna M. Seddon, Robyn C Reynolds, Heeral R. Shah, BERNARD A. ROSNER · 2011 · Ophthalmology
- Genetic and Functional Dissection of HTRA1 and LOC387715 in Age-Related Macular DegenerationZhenglin Yang, Zongzhong Tong, Yuhong Chen, Jiexi Zeng, Fang Lü, Xufang Sun, Chao Zhao, Kevin Wang, Lisa M Davey, Haoyu Chen et al. · 2010 · PLoS Genetics
- Complement component C5a activates ICAM-1 expression on human choroidal endothelial cellsSkeie, Jessica M., Fingert, John H., Russell, Stephen R., Stone, Edwin M., Mullins, Robert F. · 2010 · Investigative Opthalmology & Visual Science
- Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degenerationMihoko Suzuki, Motokazu Tsujikawa, Hiroyuki Itabe, Zhao-Jiang Du, Ping Xie, Nagakazu Matsumura, Xiaoming Fu, Renliang Zhang, Koh‐Hei Sonoda, Kensuke Egashira et al. · 2012 · Journal of Cell Science
- The complement system: a gateway to gene–environment interactions in schizophrenia pathogenesisVishwajit Laxmikant Nimgaonkar, Konasale M. R. Prasad, Kodavali V. Chowdari, Emily G. Severance, Robert H. Yolken · 2017 · Molecular Psychiatry
- Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor BTamara Montes, Agustín Tortajada, B. Paul Morgan, Santiago Rodrı́guez de Córdoba, Claire Louise Harris · 2009 · Proceedings of the National Academy of Sciences
- Complement dysregulation and disease: From genes and proteins to diagnostics and drugsSantiago Rodrı́guez de Córdoba, Agustín Tortajada, Claire Louise Harris, B. Paul Morgan · 2012 · Immunobiology
- Restoration of mesenchymal retinal pigmented epithelial cells by TGFβ pathway inhibitors: implications for age-related macular degenerationMonte J. Radeke, Carolyn M. Radeke, Ying-Hsuan Shih, Jane G. Hu, Dean Bok, Lincoln V. Johnson, Peter J. Coffey · 2015 · Genome Medicine
- The challenges and promise of complement therapeutics for ocular diseasesPark, Dong Ho, Connor, Kip M., Lambris, John D. · 2019 · Frontiers in Immunology
- Review of Genetics in Age Related Macular DegenerationSandra Rocio Montezuma, Lucia Sobrin, Johanna M. Seddon · 2007 · Seminars in Ophthalmology
- Advances in understanding of pathogenesis of aHUS and HELLPCelia J. Fang, Anna Richards, M. Kathryn Liszewski, David Kavanagh, John P. Atkinson · 2008 · British Journal of Haematology
- Nutrition and age-related eye diseases: The Alienor (Antioxydants, lipides essentiels, nutrition et maladies oculaires) studyCécile Delcourt, Jean‐François Korobelnik, Pascale Barberger‐Gateau, Marie‐Noëlle Delyfer, Marie‐Bénédicte Rougier, Mélanie Le Goff, Florence Malet, J. Colin, J.-F. Dartigues · 2010 · The journal of nutrition health & aging
- Variations in Apolipoprotein E Frequency With Age in a Pooled Analysis of a Large Group of Older PeopleMcKay, G. J., Silvestri, G., Chakravarthy, U., Dasari, S., Fritsche, L. G., Weber, B. H., Keilhauer, C. N., Klein, M. L., Francis, P. J., Klaver, C. C. et al. · 2011 · American Journal of Epidemiology
- Human C3 Deficiency Associated with Impairments in Dendritic Cell Differentiation, Memory B Cells, and Regulatory T CellsArije Ghannam, Martine Pernollet, Jean‐Luc Fauquert, Nicole Monnier, D. Ponard, Marie‐Bernadette Villiers, J. Navarro, Arlette Tridon, Joël Lunardi, Denis Gerlier et al. · 2008 · The Journal of Immunology
- CFH, C3 and ARMS2 Are Significant Risk Loci for Susceptibility but Not for Disease Progression of Geographic Atrophy Due to AMDHendrik P. N. Scholl, Monika Fleckenstein, Lars G. Fritsche, Steffen Schmitz-Valckenberg, Arno P. Göbel, Christine Adrion, Christine Herold, Claudia N. Keilhauer, Friederike Mackensen, Andreas Mößner et al. · 2009 · PLoS ONE
- Lipids, Lipoproteins, and Age-Related Macular DegenerationKatayoon B. Ebrahimi, James T. Handa · 2011 · Journal of Lipids
- Functional modules, mutational load and human genetic diseaseNorann A. Zaghloul, Nicholas Katsanis · 2010 · Trends in Genetics
- REVIEW PAPER: Animals as Models of Age-Related Macular DegenerationCaroline J. Zeiss · 2010 · Veterinary Pathology
- The Proteomics of DrusenJohn W. Crabb · 2014 · Cold Spring Harbor Perspectives in Medicine
- Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degenerationValentina Cipriani, Laura Lorés‐Motta, Fan He, Dina Fathalla, Viranga Tilakaratna, Selina McHarg, Nadhim Bayatti, İlhan E. Acar, Carel B. Hoyng, Sascha Fauser et al. · 2020 · Nature Communications
- Retinal pigment epithelium in the pathogenesis of age‐related macular degeneration and photobiomodulation as a potential therapy?Jack Ao, John P. M. Wood, Glyn Chidlow, Mark C. Gillies, Robert James Casson · 2017 · Clinical and Experimental Ophthalmology
- Analysis of Complement Expression in Light-Induced Retinal Degeneration: Synthesis and Deposition of C3 by Microglia/Macrophages Is Associated with Focal Photoreceptor DegenerationMatt Rutar, Riccardo Natoli, Peter Kozulin, Krisztina Valter, Paul A. Gatenby, Jan M. Provis · 2011 · Investigative Ophthalmology & Visual Science
- The Role of Complement in AMDPeter F. Zipfel, Nadine Lauer, Christine Skerka · 2010 · Advances in experimental medicine and biology
- Retinal Macrophages Synthesize C3 and Activate Complement in AMD and in Models of Focal Retinal DegenerationRiccardo Natoli, Nilisha Fernando, Haihan Jiao, Tanja Racic, Michele C. Madigan, Nigel L. Barnett, Joshua A. Chu‐Tan, Krisztina Valter, Jan M. Provis, Matt Rutar · 2017 · Investigative Ophthalmology & Visual Science
- C2 and CFB Genes in Age-Related Maculopathy and Joint Action with CFH and LOC387715 GenesJóhanna Jakobsdóttir, Yvette P. Conley, Daniel E. Weeks, Robert E. Ferrell, Michael B. Gorin · 2008 · PLoS ONE
- Inflammatory Mechanisms of Age-related Macular DegenerationJared E. Knickelbein, Chi‐Chao Chan, Hatice Nida Sen, Frederick L. Ferris, Robert Burton Nussenblatt · 2015 · International Ophthalmology Clinics
- Age-Related Macular DegenerationSam Khandhadia, Jocelyn Cherry, Andrew John Lotery · 2012 · Advances in experimental medicine and biology
- The molecular genetic basis of age-related macular degeneration: an overviewSaritha Katta, Inderjeet Kaur, Subhabrata Chakrabarti · 2009 · Journal of Genetics
- Mitochondrial DNA Variants Mediate Energy Production and Expression Levels for CFH, C3 and EFEMP1 Genes: Implications for Age-Related Macular DegenerationM. Cristina Kenney, Marilyn Chwa, Shari R. Atilano, Janelle M. Pavlis, Payam Falatoonzadeh, Claudio Ramírez, Deepika Malik, Tiffany Hsu, Grace Woo, Kyaw Soe et al. · 2013 · PLoS ONE
- Complement Component C3 and Risk of Age-Related Macular DegenerationDespriet, Dominiek D.G., van Duijn, Cornelia M., Oostra, Ben A., Uitterlinden, Andre G., Hofman, Albert, Wright, Alan F., ten Brink, Jacoline B., Bakker, Arne, de Jong, Paulus T.V.M., Vingerling, Johannes R. et al. · 2009 · Ophthalmology
- Genetics of age-related macular degeneration: current concepts, future directionsDeAngelis, Margaret M., Silveira, Alexandra C., Carr, Elizabeth A., Kim, Ivana K. · 2011 · Seminars in Ophthalmology
- Developments in anti-complement therapy; from disease to clinical trialClaire Louise Harris, Richard B. Pouw, David Kavanagh, Ruyue Sun, Daniel Ricklin · 2018 · Molecular Immunology
- Blue light–filtering intraocular lenses: Review of potential benefits and side effectsFiona M. Cuthbertson, Stuart N. Peirson, Katharina Wulff, F. Foster, Susan M. Downes · 2009 · Journal of Cataract & Refractive Surgery
- Nrf2 signaling modulates cigarette smoke-induced complement activation in retinal pigmented epithelial cellsLei Wang, Naoshi Kondo, Marisol Cano, Katayoon B. Ebrahimi, Takeshi Yoshida, Brad P. Barnett, Shyam S. Biswal, James T. Handa · 2014 · Free Radical Biology and Medicine
- The spectrum of phenotypes caused by variants in the CFH geneCamiel J. F. Boon, Nicole C. A. J. van de Kar, B. Jeroen Klevering, JAN E. E. KEUNEN, Frans P.M. Cremers, Caroline C. W. Klaver, Carel B. Hoyng, Mohamed R. Daha, Anneke I. den Hollander · 2009 · Molecular Immunology
- Targeting complement components C3 and C5 for the retina: Key concepts and lingering questionsBenjamin J. Kim, Dimitrios C. Mastellos, Yafeng Li, Joshua L. Dunaief, John D. Lambris · 2020 · Progress in Retinal and Eye Research
- Characterizing New-Onset Exudation in the Randomized Phase 2 FILLY Trial of Complement Inhibitor Pegcetacoplan for Geographic AtrophyCharles C. Wykoff, Philip J. Rosenfeld, Nadia Khalida Waheed, Rishi P. Singh, Nick Ronca, Jason S. Slakter, Giovanni Staurenghi, Jordi Monés, Caroline R. Baumal, Namrata Saroj et al. · 2021 · Ophthalmology
- Multiple Gene Polymorphisms in the Complement Factor H Gene Are Associated with Exudative Age-Related Macular Degeneration in ChineseTsz Kin Ng, Li Jia Chen, David T.L. Liu, Pancy O. S. Tam, Wai Man Chan, Ke Liu, Yi Jun Hu, Kelvin Kam Lung Chong, Charles Sing Lok Lau, Sylvia W. Y. Chiang et al. · 2008 · Investigative Ophthalmology & Visual Science
- Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB–FKBPL–NOTCH4 region of chromosome 6p21.3Valentina Cipriani, Hin-Tak Leung, Vincent Plagnol, Catey Bunce, Jane C. Khan, Humma Shahid, Anthony T. Moore, Simon Peter Harding, Paul N. Bishop, Caroline Hayward et al. · 2012 · Human Molecular Genetics
- Measurement of Factor H Variants in Plasma Using Variant-Specific Monoclonal Antibodies: Application to Assessing Risk of Age-Related Macular DegenerationSvetlana Hakobyan, Claire Louise Harris, Agustín Tortajada, Elena Goicoechea de Jorge, Alfredo García‐Layana, Patricia Fernández‐Robredo, Santiago Rodrı́guez de Córdoba, B. Paul Morgan · 2008 · Investigative Ophthalmology & Visual Science
- Assessing Susceptibility to Age-related Macular Degeneration with Proteomic and Genomic BiomarkersJiayin Gu, Gayle J. T. Pauer, Xiuzhen Yue, Umadevi Narendra, Gwen M. Sturgill, James Bena, Xiaorong Gu, Neal S. Peachey, Robert G. Salomon, Stephanie A. Hagstrom et al. · 2009 · Molecular & Cellular Proteomics
- Lysosomes: regulators of autophagy in the retinal pigmented epitheliumSinha, Debasish, Valapala, Mallika, Shang, Peng, Hose, Stacey, Grebe, Rhonda, Lutty, Gerard A., Zigler, J. Samuel, Kaarniranta, Kai, Handa, James T. · 2016 · Experimental Eye Research
- Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degenerationMorad Ansari, Paul McKeigue, Christine Skerka, Caroline Hayward, Igor Rudan, Véronique Vitart, Ozren Polašek, Ana-Maria Armbrecht, John R.W. Yates, Zoran Vatavuk et al. · 2013 · Human Molecular Genetics
- The significance of the complement system for the pathogenesis of age-related macular degeneration — current evidence and translation into clinical applicationPeter Charbel Issa, Victor N. Chong, Hendrik P. N. Scholl · 2010 · Graefe s Archive for Clinical and Experimental Ophthalmology
- Functional and Structural Implications of the Complement Factor H Y402H Polymorphism Associated with Age-Related Macular DegenerationRebecca J. Ormsby, Shoba Ranganathan, Joo Chuan Tong, Kim M. Griggs, David P. Dimasi, Alex William Hewitt, Kathryn P. Burdon, Jamie E. Craig, Josephine J. Hoh, David Gordon · 2008 · Investigative Ophthalmology & Visual Science
- CKD Increases the Risk of Age-Related Macular DegenerationGerald Liew, Paul Mitchell, Tien Yin Wong, Sudha K. Iyengar, Jie Jin Wang · 2008 · Journal of the American Society of Nephrology
- Modelling the Genetic Risk in Age-Related Macular DegenerationFelix Graßmann, Lars G. Fritsche, Claudia N. Keilhauer, Iris M. Heid, Bernhard H. F. Weber · 2012 · PLoS ONE
- A Novel Source of Methylglyoxal and Glyoxal in Retina: Implications for Age-Related Macular DegenerationKee Dong Yoon, Kazunori Yamamoto, Keiko Ueda, Jilin Zhou, Janet R. Sparrow · 2012 · PLoS ONE
- Elastin Gene Polymorphisms in Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal VasculopathyNaoshi Kondo, Shigeru Honda, Kazuki Ishibashi, Yasutomo Tsukahara, Akira Negi · 2008 · Investigative Ophthalmology & Visual Science
- Toll-like receptor polymorphisms and age-related macular degenerationEdwards, Albert O., Chen, Dequan, Fridley, Brooke L., James, Katherine M., Wu, Yanhong, Abecasis, Goncalo, Swaroop, Anand, Othman, Mohammad, Branham, Kari, Iyengar, Sudha K. et al. · 2008 · Investigative Opthalmology & Visual Science
- Macular Degeneration Epidemiology: Nature-Nurture, Lifestyle Factors, Genetic Risk, and Gene-Environment Interactions – The Weisenfeld Award LectureJohanna M. Seddon · 2017 · Investigative Ophthalmology & Visual Science
- Progression of Geographic Atrophy and Genotype in Age-Related Macular DegenerationMichael L. Klein, Frederick L. Ferris, Peter James Francis, Anne S. Lindblad, Emily Y. Chew, Sara Hamon, Jürg Ott · 2010 · Ophthalmology
- Local complement activation in aqueous humor in patients with age-related macular degenerationTina Schick, Marlin Steinhauer, Alexander Aslanidis, Lebriz Altay, Marcus Karlstetter, Thomas Langmann, Michael Kirschfink, Sascha Fauser · 2017 · Eye
- Assessing Susceptibility to Age-Related Macular Degeneration With Genetic Markers and Environmental FactorsYuhong Chen · 2011 · Archives of Ophthalmology
- Complement Component C3 Plays a Critical Role in Protecting the Aging Retina in a Murine Model of Age-Related Macular DegenerationJaimie Hoh Kam, Eva Lenassi, Talat H. Malik, Matthew Caleb Pickering, Glen Jeffery · 2013 · American Journal Of Pathology
- Altered Function of Factor I Caused by Amyloid β: Implication for Pathogenesis of Age-Related Macular Degeneration from DrusenJiying Wang, Kyoko Ohno‐Matsui, Takeshi Yoshida, Ariko Kojima, Noriaki Shimada, Ken‐ichi Nakahama, Olga Safranova, Nobuhisa Iwata, Takaomi C. Saido, Manabu Mochizuki et al. · 2008 · The Journal of Immunology
- Activation of the Alternative Complement Pathway in Vitreous is Controlled by Genetics in Age-Related Macular DegenerationKelly M. Loyet, Laura E DeForge, Kenneth J. Katschke, Lauri J. Diehl, Robert Graham, Lily I. Pao, Lizette Sturgeon, Sock-Cheng Lewin-Koh, Joe G. Hollyfield, Menno van Lookeren Campagne · 2012 · Investigative Ophthalmology & Visual Science
- Current therapeutic developments in atrophic age-related macular degenerationJakub Hanus, Fangkun Zhao, Shusheng Wang · 2015 · British Journal of Ophthalmology
- Genetics of Immunological and Inflammatory Components in Age-related Macular DegenerationJingsheng Tuo, Seanna Grob, Kang Zhang, Chi‐Chao Chan · 2012 · Ocular Immunology and Inflammation
- Heritability and Genome-Wide Association Study to Assess Genetic Differences between Advanced Age-related Macular Degeneration SubtypesLucia Sobrin, Stephan Ripke, Yi Yu, Jesen A. Fagerness, Tushar Bhangale, Perciliz L. Tan, Eric H. Souied, Gabriëlle H.S. Buitendijk, Joanna E. Merriam, Andrea Jane Richardson et al. · 2012 · Ophthalmology
- Complement C3 and its polymorphism: biological and clinical consequencesJoris Delanghe, Reinhart Speeckaert, Marijn M. Speeckaert · 2013 · Pathology
- Change in Drusen Volume as a Novel Clinical Trial Endpoint for the Study of Complement Inhibition in Age-related Macular DegenerationCarlos Alexandre de Amorim Garcia Filho, Zohar Yehoshua, Giovanni Gregori, Renata Portella Nunes, Fernando M. Penha, Andrew A. Moshfeghi, Kang Zhang, William J. Feuer, Philip J. Rosenfeld · 2013 · Ophthalmic surgery, lasers & imaging retina
- AMD and the alternative complement pathway: genetics and functional implicationsPerciliz L. Tan, Catherine Bowes Rickman, Nicholas Katsanis · 2016 · Human Genomics
- ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degenerationSobrin, Lucia, Reynolds, Robyn, Yu, Yi, Fagerness, Jesen, Leveziel, Nicolas, Bernstein, Paul S., Souied, Eric H., Daly, Mark J., Seddon, Johanna M. · 2011 · American Journal of Ophthalmology
- Expression and Modulation of RPE Cell Membrane Complement Regulatory ProteinsPing Yang, Jillian Tyrrell, Ian C. Han, Glenn J. Jaffe · 2009 · Investigative Ophthalmology & Visual Science
- Complement activation levels are related to disease stage in AMDHeesterbeek, Thomas J., Lechanteur, Yara T. E., Lorés-Motta, Laura, Schick, Tina, Daha, Mohamed R., Altay, Lebriz, Liakopoulos, Sandra, Smailhodzic, Dzenita, den Hollander, Anneke I., Hoyng, Carel B. et al. · 2020 · Investigative Opthalmology & Visual Science
- Complement Deposition and Microglial Activation in the Outer Retina in Light-Induced Retinopathy: Inhibition by a 5-HT 1A AgonistR.J. Collier, Yu Wang, Sherry S. Smith, Elizabeth Martin, Richard Ornberg, Kristina L. Rhoades, Carmelo Romano · 2011 · Investigative Ophthalmology & Visual Science
- Age-related macular degeneration: Complement in actionMenno van Lookeren Campagne, Erich C. Strauss, Brian L. Yaspan · 2015 · Immunobiology
- The role of the alternative pathway of complement activation in glomerular diseasesEmilia Łukawska, Magdalena Polcyn-Adamczak, Zofia Irena Niemir · 2018 · Clinical and Experimental Medicine
- Complement in age-related macular degeneration: a focus on functionDeclan Bradley, Peter F. Zipfel, A. E. Hughes · 2011 · Eye
- Risk Assessment Model for Development of Advanced Age-Related Macular DegenerationMichael L. Klein · 2011 · Archives of Ophthalmology
- Retinal Vasculitis After Intravitreal Pegcetacoplan: Report From the ASRS Research and Safety in Therapeutics (ReST) CommitteeAndré J. Witkin, Glenn J. Jaffe, Sunil K. Srivastava, Janet L. Davis, Judy E. Kim · 2023 · Journal of VitreoRetinal Diseases
- Risk- and non-risk-associated variants at the 10q26 AMD locus influence ARMS2 mRNA expression but exclude pathogenic effects due to protein deficiencyUlrike Friedrich, Connie A. Myers, Lars G. Fritsche, Andrea Milenkovic, Armin Wolf, Joseph C. Corbo, Bernhard H. F. Weber · 2011 · Human Molecular Genetics
- A local complement response by RPE causes early-stage macular degenerationFernandez-Godino, Rosario, Garland, Donita L., Pierce, Eric A. · 2015 · Human Molecular Genetics
- New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3Elizabeth Rodríguez, Pavithra M. Rallapalli, Amy J. Osborne, Stephen J. Perkins · 2014 · Bioscience Reports
- Geographic atrophy: Mechanism of disease, pathophysiology, and role of the complement systemSophie J. Bakri, Meryem Bektas, Darcie A. Sharp, Roger T. Luo, Sujata P. Sarda, Shahnaz Khan · 2023 · Journal of Managed Care & Specialty Pharmacy
- Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degenerationAnne Senabouth, Maciej Daniszewski, Grace E. Lidgerwood, Helena Hai Liang, Damián Hernández, Mehdi Mirzaei, Stacey N. Keenan, Ran Zhang, Xikun Han, Drew R. Neavin et al. · 2022 · Nature Communications
- C-Reactive Protein and CFH, ARMS2/HTRA1 Gene Variants Are Independently Associated with Risk of Macular DegenerationJohanna M. Seddon, Gary R. Gensler, BERNARD A. ROSNER · 2010 · Ophthalmology
- Implications of genetic variation in the complement system in age-related macular degenerationde Jong, Sarah, Gagliardi, Giuliana, Garanto, Alejandro, de Breuk, Anita, Lechanteur, Yara T.E., Katti, Suresh, van den Heuvel, Lambert P., Volokhina, Elena B., den Hollander, Anneke I. · 2021 · Progress in Retinal and Eye Research
- Plasma Protein Pentosidine and Carboxymethyllysine, Biomarkers for Age-related Macular DegenerationJiaqian Ni, Xianglin Yuan, Jiayin Gu, Xiuzhen Yue, Xiaorong Gu, Ram H. Nagaraj, John W. Crabb · 2009 · Molecular & Cellular Proteomics
- C3 Polymorphisms and Allograft Outcome in Renal TransplantationMira Varagunam, Muhammad Yaqoob, Bernd Döhler, Gerhard Opelz · 2009 · New England Journal of Medicine
- Targeting C3b/C4b and VEGF with a bispecific fusion protein optimized for neovascular age-related macular degeneration therapyShiqi Yang, Tong Li, Huixun Jia, Min Gao, Yiming Li, Xiaoling Wan, Zhen Huang, Min Li, Yuanqi Zhai, Xiaomeng Li et al. · 2022 · Science Translational Medicine
- Central Areolar Choroidal Dystrophy (CACD) and Age-Related Macular Degeneration (AMD): Differentiating Characteristics in Multimodal ImagingDženita Smailhodzic, Monika Fleckenstein, Thomas Theelen, Camiel J. F. Boon, Ramon A. C. van Huet, Johannes P. H. van de Ven, Anneke I. den Hollander, Steffen Schmitz-Valckenberg, Carel B. Hoyng, Bernhard H. F. Weber et al. · 2011 · Investigative Ophthalmology & Visual Science
- Cuticular drusen: Stars in the skyCamiel J. F. Boon, Johannes P. H. van de Ven, Carel B. Hoyng, Anneke I. den Hollander, B. Jeroen Klevering · 2013 · Progress in Retinal and Eye Research
- Associations Between Abnormal Rod-Mediated Dark Adaptation and Health and Functioning in Older Adults With Normal Macular HealthCynthia J. Owsley, Carrie Huisingh, Gregory R. Jackson, Christine A. Curcio, Alexander J. Szalai, Nassrin Dashti, Mark E. Clark, Kia Rookard, Mark A. McCrory, Tyler T. Wright et al. · 2014 · Investigative Ophthalmology & Visual Science
- Ocular Vascular Diseases: From Retinal Immune Privilege to InflammationXudong Wang, Tianxi Wang, Enton Lam, David Álvarez, Ye Sun · 2023 · International Journal of Molecular Sciences
- Complement regulators in human disease: lessons from modern geneticsM. Kathryn Liszewski, John P. Atkinson · 2014 · Journal of Internal Medicine
- ASSOCIATION STUDY OF COMPLEMENT FACTOR H, C2, CFB, AND C3 AND AGE-RELATED MACULAR DEGENERATION IN A HAN CHINESE POPULATIONXiaoqi Liu, Peiquan Zhao, Shibo Tang, Fang Lü, Jianbin Hu, Chuntao Lei, Xian Qing Yang, Ying Lin, Shi Ma, Jiyun Yang et al. · 2010 · Retina
- Complement Component 3 ( C3 ) Haplotypes and Risk of Advanced Age-Related Macular DegenerationKyu Hyung Park, Brooke L. Fridley, Euijung Ryu, Nirubol Tosakulwong, Albert O. Edwards · 2009 · Investigative Ophthalmology & Visual Science