Complement C3 Variant and the Risk of Age-Related Macular Degeneration

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3. Cellular models and therapies for age-related macular degeneration
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4. The role of complement in ocular pathology
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5. Association of Genetic Polymorphisms and Age-Related Macular Degeneration in Chinese Population
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6. Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration
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8. Recent advances in the management of dry age-related macular degeneration: A review
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9. 670-nm light treatment reduces complement propagation following retinal degeneration
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10. Genetics and molecular pathology of Stargardt-like macular degeneration
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11. miRNAs as potential therapeutic targets for age-related macular degeneration
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12. Genetics and genetic testing for age-related macular degeneration
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13. A Review of Current and Future Management of Geographic Atrophy
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14. Complement Regulation at Necrotic Cell Lesions Is Impaired by the Age-Related Macular Degeneration-Associated Factor-H His402 Risk Variant
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15. Multifactor Effects and Evidence of Potential Interaction between Complement Factor H Y402H and LOC387715 A69S in Age-Related Macular Degeneration
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16. T Cells and Macrophages Responding to Oxidative Damage Cooperate in Pathogenesis of a Mouse Model of Age-Related Macular Degeneration
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17. Connecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and γδT-cells
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18. Age-Related Macular Degeneration: Clinical Findings, Histopathology and Imaging Techniques
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19. Toll-like Receptor 3 Is Required for Development of Retinopathy Caused by Impaired All-trans-retinal Clearance in Mice
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20. CD11c+ macrophages are proangiogenic and necessary for experimental choroidal neovascularization
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21. Suppression of Drusen Formation by Compstatin, a Peptide Inhibitor of Complement C3 activation, on Cynomolgus Monkey with Early-Onset Macular Degeneration
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22. Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: A systems biology based approach
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23. A Novel Role of Complement in Retinal Degeneration
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24. Age-related macular degeneration-associated variants at chromosome 10q26 do not significantly alter ARMS2 and HTRA1 transcript levels in the human retina.
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25. Role of Complement Cascade in Abdominal Aortic Aneurysms
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26. Fat Intake and CNS Functioning: Ageing and Disease
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27. The Association Between Complement Component 2/Complement Factor B Polymorphisms and Age-related Macular Degeneration: A HuGE Review and Meta-Analysis
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28. Mechanism of Inflammation in Age-Related Macular Degeneration: An Up-to-Date on Genetic Landmarks
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29. Altered gene expression in dry age-related macular degeneration suggests early loss of choroidal endothelial cells.
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30. Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration
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31. Bisretinoids of RPE Lipofuscin: Trigger for Complement Activation in Age-Related Macular Degeneration
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32. Genetic analysis of typical wet-type age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese population
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33. Association of age-related macular degeneration and reticular macular disease with cardiovascular disease
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34. Concordance of Disease Progression in Bilateral Geographic Atrophy Due to AMD
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35. Elevated Plasma Levels of C3a Complement Compound in the Exudative Form of Age-Related Macular Degeneration
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36. A search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways
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37. Evaluation of Serum Lipid Concentrations and Genetic Variants at High-Density Lipoprotein Metabolism Loci and TIMP3 in Age-Related Macular Degeneration
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38. Further Assessment of the Complement Component 2 and Factor B Region Associated with Age-Related Macular Degeneration
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39. Complement Mediated Signaling on Pulmonary CD103+ Dendritic Cells Is Critical for Their Migratory Function in Response to Influenza Infection
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40. Complement dysregulation in AMD: RPE-Bruch’s membrane-choroid
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41. Genetic Factors for Choroidal Neovascularization Associated with High Myopia
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42. Complement Factor H Y402H Variant and Risk of Age-Related Macular Degeneration in Asians: A Systematic Review and Meta-Analysis
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43. Chemokine Receptor Expression in Peripheral Blood Monocytes from Patients with Neovascular Age-Related Macular Degeneration
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44. Complement cascade functions during brain development and neurodegeneration
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45. Therapeutic targeting of the complement system in age‐related macular degeneration: a review
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46. Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration
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47. Late-onset retinal macular degeneration: clinical insights into an inherited retinal degeneration
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48. Synthesis and Propagation of Complement C3 by Microglia/Monocytes in the Aging Retina
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49. Interlink between Inflammation and Oxidative Stress in Age-Related Macular Degeneration: Role of Complement Factor H
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50. Genetics of age-related macular degeneration
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51. Proteomic Landscape of the Human Choroid–Retinal Pigment Epithelial Complex
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52. Matrix Metalloproteinase Activity Creates Pro-Angiogenic Environment in Primary Human Retinal Pigment Epithelial Cells Exposed to Complement
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53. Three New Genetic Loci (R1210C in CFH, Variants in COL8A1 and RAD51B) Are Independently Related to Progression to Advanced Macular Degeneration
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54. Kidney function, albuminuria and age-related macular degeneration in NHANES III
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55. Polymorphisms in the VEGFA and VEGFR-2 genes and neovascular age-related macular degeneration.
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56. The influence of genetics on response to treatment with ranibizumab (Lucentis) for age-related macular degeneration: the Lucentis Genotype Study (an American Ophthalmological Society thesis).
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57. Inflammation in the pathogenesis of age-related macular degeneration
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58. Complement regulation in the eye: implications for age-related macular degeneration
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59. Age-Related Macular Degeneration Preferred Practice Pattern®
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60. Future Therapies of Wet Age-Related Macular Degeneration
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61. Genomic aspects of age-related macular degeneration
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62. Validation of a Prediction Algorithm for Progression to Advanced Macular Degeneration Subtypes
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63. Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration
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68. Zinc Supplementation Inhibits Complement Activation in Age-Related Macular Degeneration
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69. An association study of SERPING1 gene and age-related macular degeneration in a Han Chinese population.
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70. Complement Inhibitors in Age-Related Macular Degeneration: A Potential Therapeutic Option
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71. Alternative Complement Pathway Deficiency Ameliorates Chronic Smoke-Induced Functional and Morphological Ocular Injury
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72. Emerging roles for nuclear receptors in the pathogenesis of age-related macular degeneration
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73. Impact of the Common Genetic Associations of Age-Related Macular Degeneration upon Systemic Complement Component C3d Levels
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74. Age-related macular degeneration: genetic and clinical findings
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75. A PHASE IA DOSE-ESCALATION STUDY OF THE ANTI-FACTOR D MONOCLONAL ANTIBODY FRAGMENT FCFD4514S IN PATIENTS WITH GEOGRAPHIC ATROPHY
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78. Innate Immune Network in the Retina Activated by Optic Nerve Crush
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80. Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations
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85. Inflammation and Cell Death in Age-Related Macular Degeneration: An Immunopathological and Ultrastructural Model
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86. Complete Blood Cell Count–Derived Inflammation Biomarkers in Men with Age-Related Macular Degeneration
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89. Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)-β Signaling in the Retinal Pigment Epithelium
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91. C9-R95X Polymorphism in Patients with Neovascular Age-Related Macular Degeneration
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92. Ocular macrophage origin and heterogeneity during steady state and experimental choroidal neovascularization
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93. Genetic Factors in Nonsmokers with Age‐Related Macular Degeneration Revealed Through Genome‐Wide Gene‐Environment Interaction Analysis
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94. Plasma levels of complement proteins from the alternative pathway in patients with age-related macular degeneration are independent of Complement Factor H Tyr⁴⁰²His polymorphism.
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95. Association of C3 Gene Polymorphisms with Neovascular Age-Related Macular Degeneration in a Chinese Population
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96. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
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97. Rare Functional Variants in Complement Genes and Anti-FH Autoantibodies-Associated aHUS
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98. Angiogenesis in eye disease: immunity gained or immunity lost?
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99. Complement-Mediated Microglial Phagocytosis and Pathological Changes in the Development and Degeneration of the Visual System
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100. The role of CRP and inflammation in the pathogenesis of age-related macular degeneration
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