Cited by 1,232Heart Failure Treatment and ManagementTelemedicine and Telehealth ImplementationMobile Health and mHealth Applications

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Telemonitoring in Patients with Heart Failure

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Chaudhry, Sarwat I., Mattera, Jennifer A., Curtis, Jeptha P., Spertus, John A., Herrin, Jeph, Lin, Zhenqiu, Phillips, Christopher O., Hodshon, Beth V., Cooper, Lawton S., Krumholz, Harlan M.·2010·New England Journal of Medicine

DOI 10.1056/nejmoa1010029PMC PMC3237394

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Abstract

BACKGROUND: Small studies suggest that telemonitoring may improve heart-failure outcomes, but its effect in a large trial has not been established. METHODS: We randomly assigned 1653 patients who had recently been hospitalized for heart failure to undergo either telemonitoring (826 patients) or usual care (827 patients). Telemonitoring was accomplished by means of a telephone-based interactive voice-response system that collected daily information about symptoms and weight that was reviewed by the patients' clinicians. The primary end point was readmission for any reason or death from any cause within 180 days after enrollment. Secondary end points included hospitalization for heart failure, number of days in the hospital, and number of hospitalizations. RESULTS: The median age of the patients was 61 years; 42.0% were female, and 39.0% were black. The telemonitoring group and the usual-care group did not differ significantly with respect to the primary end point, which occurred in 52.3% and 51.5% of patients, respectively (difference, 0.8 percentage points; 95% confidence interval [CI], -4.0 to 5.6; P=0.75 by the chi-square test). Readmission for any reason occurred in 49.3% of patients in the telemonitoring group and 47.4% of patients in the usual-care group (difference, 1.9 percentage points; 95% CI, -3.0 to 6.7; P=0.45 by the chi-square test). Death occurred in 11.1% of the telemonitoring group and 11.4% of the usual care group (difference, -0.2 percentage points; 95% CI, -3.3 to 2.8; P=0.88 by the chi-square test). There were no significant differences between the two groups with respect to the secondary end points or the time to the primary end point or its components. No adverse events were reported. CONCLUSIONS: Among patients recently hospitalized for heart failure, telemonitoring did not improve outcomes. The results indicate the importance of a thorough, independent evaluation of disease-management strategies before their adoption. (Funded by the National Heart, Lung, and Blood Institute; ClinicalTrials.gov number, NCT00303212.).

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Authors: Chaudhry, S. I., Mattera, J. A., Curtis, J. P., Spertus, J. A., Herrin, J., Lin, Z., Phillips, C. O., Hodshon, B. V., Cooper, L. S., & Krumholz, H. M.
Affiliations: Yale University (US)
Yale New Haven Hospital (US)
Saint Luke's Health System (US)
Morehouse School of Medicine (US)
National Heart, Lung, and Blood Institute (US)
ORCID: Chaudhry, Sarwat I.
Mattera, Jennifer A.
Curtis, Jeptha P.
Spertus, John A.
Herrin, Jeph
Lin, Zhenqiu
Cooper, Lawton S.
Krumholz, Harlan M.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2010-12-09
Volume: 363
Issue: 24
Pages: 2301-2309
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmoa1010029
PMC: PMC3237394
OpenAlex: W2016468586
Cited by: 1,232
References: 18
Citations by year: 2026: 31 · 2025: 44 · 2024: 53 · 2023: 56 · 2022: 58 · 2021: 92 · 2020: 79 · 2019: 57 · 2018: 82 · 2017: 97 · 2016: 92 · 2015: 108 · 2014: 107 · 2013: 99 · 2012: 88
FWCI: 59.93
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute on Aging (K23AG030986)
National Heart, Lung, and Blood Institute (R01HL080228)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
Keywords: remote patient monitoring, heart failure, hospital readmission, mortality, heart failure hospitalization, symptom monitoring, weight monitoring, disease management strategies
MeSH terms: Aged, Female, Heart Failure, Home Care Services, Hospitalization, Humans, Male, Middle Aged, Monitoring, Physiologic, Patient Readmission, Severity of Illness Index, Telemedicine, Kaplan-Meier Estimate

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