Krumholz, Harlan M.

The mutational constraint spectrum quantified from variation in 141,456 humans

Karczewski, K. J., Francioli, L. C., Tiao, G., Cummings, B. B., Alföldi, J., Wang, Q., Collins, R. L., Laricchia, K. M., Ganna, A., Birnbaum, D. P., et al. (2020) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 9,434

Extrapulmonary manifestations of COVID-19

Gupta, A., Madhavan, M. V., Sehgal, K., Nair, N., Mahajan, S., Sehrawat, T. S., Bikdeli, B., Ahluwalia, N., Ausiello, J. C., Wan, E. Y., et al. (2020) · Nature Medicine

COVID-19 Clinical Research StudiesLong-Term Effects of COVID-19

Cited by 3,185

2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction

O'Gara, P. T., Kushner, F. G., Ascheim, D. D., Casey, D. E., Chung, M. K., de Lemos, J. A., Ettinger, S. M., Fang, J. C., Fesmire, F. M., Franklin, B. A., et al. (2013) · Journal of the American College of Cardiology

Acute Myocardial Infarction ResearchAntiplatelet Therapy and Cardiovascular Diseases

Cited by 2,625

Participation in Cancer Clinical Trials: Race-, Sex-, and Age-Based Disparities

Murthy, V. H., Krumholz, H. M., & Gross, C. P. (2004) · JAMA

Ethics in Clinical ResearchGlobal Cancer Incidence and Screening

Cited by 2,078

Foundation models for generalist medical artificial intelligence

Moor, M., Banerjee, O., Abad, Z. S. H., Krumholz, H. M., Leskovec, J., Topol, E. J., & Rajpurkar, P. (2023) · Nature

Artificial Intelligence in Healthcare and EducationMachine Learning in Healthcare

Cited by 2,028

A genomic mutational constraint map using variation in 76,156 human genomes

Chen, S., Francioli, L. C., Goodrich, J. K., Collins, R. L., Kanai, M., Wang, Q., Alföldi, J., Watts, N. A., Vittal, C., Gauthier, L. D., et al. (2024) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 1,727

Acute Myocardial Infarction in Women: A Scientific Statement From the American Heart Association

Mehta, L. S., Beckie, T. M., DeVon, H. A., Grines, C. L., Krumholz, H. M., Johnson, M. N., Lindley, K. J., Vaccarino, V., Wang, T. Y., Watson, K. E., et al. (2016) · Circulation

Acute Myocardial Infarction ResearchSex and Gender in Healthcare

Cited by 1,244

Telemonitoring in patients with heart failure

Chaudhry, S. I., Mattera, J. A., Curtis, J. P., Spertus, J. A., Herrin, J., Lin, Z., Phillips, C. O., Hodshon, B. V., Cooper, L. S., & Krumholz, H. M. (2010) · New England Journal of Medicine

Heart Failure Treatment and ManagementTelemedicine and Telehealth Implementation

Cited by 1,232

Post-Hospital Syndrome — An Acquired, Transient Condition of Generalized Risk

Krumholz, H. M. (2013) · New England Journal of Medicine

Hospital Admissions and OutcomesIntensive Care Unit Cognitive Disorders

Cited by 1,218

Association between physical exercise and mental health in 1·2 million individuals in the USA between 2011 and 2015: a cross-sectional study

Chekroud, S. R., Gueorguieva, R., Zheutlin, A. B., Paulus, M., Krumholz, H. M., Krystal, J. H., & Chekroud, A. M. (2018) · The Lancet Psychiatry

Physical Activity and HealthMental Health Treatment and Access

Cited by 1,172

Prevalence, awareness, treatment, and control of hypertension in China: data from 1·7 million adults in a population-based screening study (China PEACE Million Persons Project)

Lu, J., Lu, Y., Wang, X., Li, X., Linderman, G. C., Wu, C., Cheng, X., Mu, L., Zhang, H., Liu, J., et al. (2017) · The Lancet

Blood Pressure and Hypertension StudiesSodium Intake and Health

Cited by 1,133

A structural variation reference for medical and population genetics

Collins, R. L., Brand, H., Karczewski, K. J., Zhao, X., Alföldi, J., Francioli, L. C., Khera, A. V., Lowther, C., Gauthier, L. D., Wang, H., et al. (2020) · Nature

Genomic variations and chromosomal abnormalitiesGenomics and Rare Diseases

Cited by 1,037

Quality of primary health care in China: challenges and recommendations

Li, X., Krumholz, H. M., Yip, W., Cheng, K. K., De Maeseneer, J., Meng, Q., Mossialos, E., Li, C., Lu, J., Su, M., et al. (2020) · The Lancet

Primary Care and Health OutcomesHealthcare Systems and Practices

Cited by 914

Trends in survival after in-hospital cardiac arrest

Girotra, S., Nallamothu, B. K., Spertus, J. A., Li, Y., Krumholz, H. M., & Chan, P. S. (2012) · New England Journal of Medicine

Cardiac Arrest and ResuscitationPalliative Care and End-of-Life Issues

Cited by 895

Increasing value and reducing waste: addressing inaccessible research

Chan, A.-W., Song, F., Vickers, A., Jefferson, T., Dickersin, K., Gøtzsche, P. C., Krumholz, H. M., Ghersi, D., & van der Worp, H. B. (2014) · The Lancet

Research Data Management PracticesAcademic Publishing and Open Access

Cited by 887

2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons

Fihn, S. D., Gardin, J. M., Abrams, J., Berra, K., Blankenship, J. C., Dallas, A. P., Douglas, P. S., Foody, J. M., Gerber, T. C., Hinderliter, A. L., et al. (2012) · Circulation

Coronary Interventions and DiagnosticsCardiac Imaging and Diagnostics

Cited by 845

The Obesity Paradox: Body Mass Index and Outcomes in Patients With Heart Failure

Curtis, J. P., Selter, J. G., Wang, Y., Rathore, S. S., Jovin, I. S., Jadbabaie, F., Kosiborod, M., Portnay, E. L., Sokol, S. I., Bader, F., et al. (2005) · Archives of Internal Medicine

Heart Failure Treatment and ManagementCardiovascular Function and Risk Factors

Cited by 809

Representation of the Elderly, Women, and Minorities in Heart Failure Clinical Trials

Heiat, A., Gross, C. P., & Krumholz, H. M. (2002) · Archives of Internal Medicine

Heart Failure Treatment and ManagementEthics in Clinical Research

Cited by 723

Admission Glucose and Mortality in Elderly Patients Hospitalized With Acute Myocardial Infarction: Implications for Patients With and Without Recognized Diabetes

Kosiborod, M., Rathore, S. S., Inzucchi, S. E., Masoudi, F. A., Wang, Y., Havranek, E. P., & Krumholz, H. M. (2005) · Circulation

Hyperglycemia and glycemic control in critically ill and hospitalized patientsAcute Myocardial Infarction Research

Cited by 666

Primary Prevention of Coronary Heart Disease: Guidance From Framingham: A Statement for Healthcare Professionals From the AHA Task Force on Risk Reduction

Grundy, S. M., Balady, G. J., Criqui, M. H., Fletcher, G., Greenland, P., Hiratzka, L. F., Houston-Miller, N., Kris-Etherton, P., Krumholz, H. M., LaRosa, J., et al. (1998) · Circulation

Health Promotion and Cardiovascular PreventionCardiovascular Health and Risk Factors

Cited by 609

Big data and new knowledge in medicine: the thinking, training, and tools needed for a learning health system.

Krumholz, H. M. (2014) · Health Affairs

Big Data Technologies and ApplicationsArtificial Intelligence in Healthcare

Cited by 589

Efficacy and Safety of Low-Carbohydrate Diets: A Systematic Review

Bravata, D. M., Sanders, L., Huang, J., Krumholz, H. M., Olkin, I., Gardner, C. D., & Bravata, D. M. (2003) · JAMA

Diet and metabolism studiesDietary Effects on Health

Cited by 561

Risks Associated With Statin Therapy: A Systematic Overview of Randomized Clinical Trials

Kashani, A., Phillips, C. O., Foody, J. M., Wang, Y., Mangalmurti, S., Ko, D. T., & Krumholz, H. M. (2006) · Circulation

Lipoproteins and Cardiovascular HealthCancer, Lipids, and Metabolism

Cited by 474

Thiazolidinediones, Metformin, and Outcomes in Older Patients With Diabetes and Heart Failure: An Observational Study

Masoudi, F. A., Inzucchi, S. E., Wang, Y., Havranek, E. P., Foody, J. M., & Krumholz, H. M. (2005) · Circulation

Diabetes Treatment and ManagementHeart Failure Treatment and Management

Cited by 458