The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Everolimus-Eluting Stents or Bypass Surgery for Multivessel Coronary Disease
Open accessAbstract
BACKGROUND: Results of trials and registry studies have shown lower long-term mortality after coronary-artery bypass grafting (CABG) than after percutaneous coronary intervention (PCI) among patients with multivessel disease. These previous analyses did not evaluate PCI with second-generation drug-eluting stents. METHODS: In an observational registry study, we compared the outcomes in patients with multivessel disease who underwent CABG with the outcomes in those who underwent PCI with the use of everolimus-eluting stents. The primary outcome was all-cause mortality. Secondary outcomes were the rates of myocardial infarction, stroke, and repeat revascularization. Propensity-score matching was used to assemble a cohort of patients with similar baseline characteristics. RESULTS: Among 34,819 eligible patients, 9223 patients who underwent PCI with everolimus-eluting stents and 9223 who underwent CABG had similar propensity scores and were included in the analyses. At a mean follow-up of 2.9 years, PCI with everolimus-eluting stents, as compared with CABG, was associated with a similar risk of death (3.1% per year and 2.9% per year, respectively; hazard ratio, 1.04; 95% confidence interval [CI], 0.93 to 1.17; P=0.50), higher risks of myocardial infarction (1.9% per year vs. 1.1% per year; hazard ratio, 1.51; 95% CI, 1.29 to 1.77; P<0.001) and repeat revascularization (7.2% per year vs. 3.1% per year; hazard ratio, 2.35; 95% CI, 2.14 to 2.58; P<0.001), and a lower risk of stroke (0.7% per year vs. 1.0% per year; hazard ratio, 0.62; 95% CI, 0.50 to 0.76; P<0.001). The higher risk of myocardial infarction with PCI than with CABG was not significant among patients with complete revascularization but was significant among those with incomplete revascularization (P=0.02 for interaction). CONCLUSIONS: In a contemporary clinical-practice registry study, the risk of death associated with PCI with everolimus-eluting stents was similar to that associated with CABG. PCI was associated with a higher risk of myocardial infarction (among patients with incomplete revascularization) and repeat revascularization but a lower risk of stroke. (Funded by Abbott Vascular.).
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Cites
The central role of the propensity score in observational studies for causal effects
ROSENBAUM, P. R., & RUBIN, D. B. (1983) · Biometrika · doi:10.1093/biomet/70.1.41 · Cited by 31,241
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2014 ESC/EACTS Guidelines on myocardial revascularization
Kolh, P., Windecker, S., Alfonso, F., Collet, J.-P., Cremer, J., Falk, V., Filippatos, G., Hamm, C., Head, S. J., Jüni, P., et al. (2014) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezu366 · Cited by 4,199
Using Propensity Scores to Help Design Observational Studies: Application to the Tobacco Litigation
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Mohr, F. W., Morice, M.-C., Kappetein, A. P., Feldman, T. E., Ståhle, E., Colombo, A., Mack, M. J., Holmes, D. R., Morel, M.-A., Dyck, N. V., et al. (2013) · The Lancet · doi:10.1016/s0140-6736(13)60141-5 · Cited by 1,789
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Long-Term Outcomes of Coronary-Artery Bypass Grafting versus Stent Implantation
Hannan, E. L., Racz, M. J., Walford, G., Jones, R. H., Ryan, T. J., Bennett, E., Culliford, A. T., Isom, O. W., Gold, J. P., & Rose, E. A. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa040316 · Cited by 664
Self-citationComparative Effectiveness of Revascularization Strategies
Weintraub, W. S., Grau-Sepulveda, M. V., Weiss, J. M., O'Brien, S. M., Peterson, E. D., Kolm, P., Zhang, Z., Klein, L. W., Shaw, R. E., McKay, C., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1110717 · Cited by 608
Drug-Eluting Stents vs. Coronary-Artery Bypass Grafting in Multivessel Coronary Disease
Hannan, E. L., Wu, C., Walford, G., Culliford, A. T., Gold, J. P., Smith, C. R., Higgins, R. S. D., Carlson, R. E., & Jones, R. H. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa071804 · Cited by 541
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2018 ESC/EACTS guidelines on myocardial revascularization
Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehy394 · Cited by 7,167
Cosentino, F., Grant, P. J., Aboyans, V., Bailey, C. J., Ceriello, A., Delgado, V., Federici, M., Filippatos, G., Grobbee, D. E., Hansen, T. B., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz486 · Cited by 4,763
2018 ESC/EACTS Guidelines on myocardial revascularization
Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · EuroIntervention · doi:10.4244/eijy19m01_01 · Cited by 1,259
2018 ESC/EACTS Guidelines on myocardial revascularization
Sousa-Uva, M., Neumann, F.-J., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezy289 · Cited by 989
Head, S. J., Milojevic, M., Daemen, J., Ahn, J.-M., Boersma, E., Christiansen, E. H., Domanski, M. J., Farkouh, M. E., Flather, M., Fuster, V., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)30423-9 · Cited by 734
Metadata
- Authors
- Bangalore, S., Guo, Y., Samadashvili, Z., Blecker, S., Xu, J., & Hannan, E. L.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2015-03-26
- Volume
- 372
- Issue
- 13
- Pages
- 1213-1222
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2152735600
- Cited by
- 288
- References
- 21
- FWCI
- 35.15
- Type
- journal article
- Language
- en
- Open access
- bronze
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