The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Incidence of Dementia over Three Decades in the Framingham Heart Study
Open accessAbstract
BACKGROUND: The prevalence of dementia is expected to soar as the average life expectancy increases, but recent estimates suggest that the age-specific incidence of dementia is declining in high-income countries. Temporal trends are best derived through continuous monitoring of a population over a long period with the use of consistent diagnostic criteria. We describe temporal trends in the incidence of dementia over three decades among participants in the Framingham Heart Study. METHODS: Participants in the Framingham Heart Study have been under surveillance for incident dementia since 1975. In this analysis, which included 5205 persons 60 years of age or older, we used Cox proportional-hazards models adjusted for age and sex to determine the 5-year incidence of dementia during each of four epochs. We also explored the interactions between epoch and age, sex, apolipoprotein E ε4 status, and educational level, and we examined the effects of these interactions, as well as the effects of vascular risk factors and cardiovascular disease, on temporal trends. RESULTS: The 5-year age- and sex-adjusted cumulative hazard rates for dementia were 3.6 per 100 persons during the first epoch (late 1970s and early 1980s), 2.8 per 100 persons during the second epoch (late 1980s and early 1990s), 2.2 per 100 persons during the third epoch (late 1990s and early 2000s), and 2.0 per 100 persons during the fourth epoch (late 2000s and early 2010s). Relative to the incidence during the first epoch, the incidence declined by 22%, 38%, and 44% during the second, third, and fourth epochs, respectively. This risk reduction was observed only among persons who had at least a high school diploma (hazard ratio, 0.77; 95% confidence interval, 0.67 to 0.88). The prevalence of most vascular risk factors (except obesity and diabetes) and the risk of dementia associated with stroke, atrial fibrillation, or heart failure have decreased over time, but none of these trends completely explain the decrease in the incidence of dementia. CONCLUSIONS: Among participants in the Framingham Heart Study, the incidence of dementia has declined over the course of three decades. The factors contributing to this decline have not been completely identified. (Funded by the National Institutes of Health.).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Higher childhood education levels and lifelong higher educational attainment reduce dementia risk.2, 35, 36, 37”
From Dementia prevention, intervention, and care: 2020 report of the Lancet Commission (2020) · cites this paper as [36]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Another key issue is that air pollution levels have been dropping over time in many areas of the world, and dementia incidence, as well, appears to have declined in North America and Europe in recent decades (Satizabal et al. 2016; Wolters et al. 2020).”
From Exposure to Air Pollution in Relation to Risk of Dementia and Related Outcomes: An Updated Systematic Review of the Epidemiological Literature (2021) · cites this paper as Satizabal et al. 2016
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“The Lancet Commission on Dementia Prevention, Intervention, and Care suggested that lifestyle modifications may already have an influence on dementia risk decades before the onset of dementia.3-8”
From Awareness of dementia risk reduction among current and future healthcare professionals: A survey study (2021) · cites this paper as [5]
Experimental — accuracy not yet measuredIn the citing paper
“Decades of efforts to reduce stroke and cardiovascular risks by the AHA/ASA and other health organizations and, more recently, to promote cardiovascular health are likely to have already contributed to the declining incidence of dementia.172”
From Defining Optimal Brain Health in Adults: A Presidential Advisory From the American Heart Association/American Stroke Association (2017) · cites this paper as [172]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915
Global prevalence of dementia: a Delphi consensus study
Ferri, C. P., Prince, M. J., Brayne, C., Brodaty, H., Fratiglioni, L., Ganguli, M., Hall, K. S., Hasegawa, K., Hendrie, H. C., Huang, Y., et al. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67889-0 · Cited by 5,336
Winblad, B., Palmer, K., Kivipelto, M., Jelic, V., Fratiglioni, L., Wahlund, L. ‐., Nordberg, A., Bäckman, L., Albert, M., Almkvist, O., et al. (2004) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01380.x · Cited by 4,946
The global prevalence of dementia: a systematic review and metaanalysis.
Prince, M., Bryce, R., Albanese, E., Wimo, A., Ribeiro, W., & Ferri, C. P. (2013) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2012.11.007 · Cited by 4,941
Román, G. C., Tatemichi, T. K., Erkinjuntti, T., Cummings, J. L., Masdeu, J. C., Garcia, J. H., Amaducci, L., Orgogozo, J.-M., Brun, A., Hofman, A., et al. (1993) · Neurology · doi:10.1212/wnl.43.2.250 · Cited by 4,921
The projected effect of risk factor reduction on Alzheimer's disease prevalence
Barnes, D. E., & Yaffe, K. S. (2011) · The Lancet Neurology · doi:10.1016/s1474-4422(11)70072-2 · Cited by 2,846
Epidemiological approaches to heart disease: the Framingham study
Dawber, T. R., Meadors, G. F., & Moore, F. E. (1951) · American Journal of Public Health and the Nations Health · doi:10.2105/ajph.41.3.279 · Cited by 2,148
Probability of stroke: a risk profile from the Framingham Study.
Wolf, P. A., D'Agostino, R. B., Belanger, A. J., & Kannel, W. B. (1991) · Stroke · doi:10.1161/01.str.22.3.312 · Cited by 1,782
Research works printed but not linked: 2
- Harwood RH, 2004, Bull World Health Organ, 82, 251
- Manton KC, 2005, Adv Gerontol, 16, 30
Cited by
Sorted by citations
Items 701–800 of 1,000
Srisuwan, P., Nakawiro, D., Chansirikarnjana, S., Kuha, O., Kengpanich, S., & Gesakomol, K. (2020) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2020.14 · Cited by 5
Zhang, L., Ngo, A. D., Thomas, J., Burkhardt, H. A., Parsey, C. M., Au, R., & Ghomi, R. H. (2021) · Exploration of Medicine · doi:10.37349/emed.2021.00044 · Cited by 6
Establishing cognitive baseline in three generations: Framingham Heart Study
Yang, J., Ang, T. F. A., Lu, S., Liu, X., Devine, S., Au, R., & Liu, C. (2023) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.12416 · Cited by 5
What have clinical trials taught us about brain health?
Lee, K., & Bae, H. (2023) · Cerebral Circulation - Cognition and Behavior · doi:10.1016/j.cccb.2023.100199 · Cited by 5
Novel therapeutic approaches for targeting Alzheimer’s disease
Khodakiya, A., Chaudhary, S., Chaudhary, A., & Prajapati, B. G. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13205-6.00020-0 · Cited by 5
Gómez‐Guijarro, M. D., Cavero‐Redondo, I., Saz‐Lara, A., Pascual‐Morena, C., Álvarez-Bueno, C., & Martínez‐García, I. (2024) · Cognitive Neurodynamics · doi:10.1007/s11571-024-10138-5 · Cited by 5
Maron, J. L., & Jones, G. B. (2018) · Clinical Therapeutics · doi:10.1016/j.clinthera.2018.01.004 · Cited by 5
Role-specific Language Models for Processing Recorded Neuropsychological Exams
Alhanai, T., Au, R., & Glass, J. R. (2018) · Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies (NAACL-HLT) · doi:10.18653/v1/n18-2117 · Cited by 5
Wang, Q., Initiative, O. B. O. A. D. N., He, C., Zhu, Y., Zhang, Q., Zhang, Z., & Xie, C. (2020) · Aging · doi:10.18632/aging.103573 · Cited by 5
Overton, M., Pihlsgård, M., & Elmståhl, S. (2022) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1002/trc2.12260 · Cited by 5
Ijaz, S. H., Minhas, A. M. K., Ghoneem, A., Khan, S. U., Sharma, G. V., Mehta, N. K., Kalra, A., Khan, S. S., Warraich, H. J., Michos, E. D., et al. (2022) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2022.06.007 · Cited by 5
Cerebrovascular abnormalities in Alzheimer’s dementia: a more tractable treatment target?
Markus, H. S. (2017) · Brain · doi:10.1093/brain/awx161 · Cited by 5
Liu, W., Wu, Y., Bai, L., Ni, J., Tu, J., Liu, J., Deng, Q., Ning, X., & Wang, J. (2018) · Neuroepidemiology · doi:10.1159/000490496 · Cited by 5
Cross-validation of the screening scale in an adult protective services sample
Campbell, R., Gross, E., & Lichtenberg, P. A. (2018) · Journal of Elder Abuse & Neglect · doi:10.1080/08946566.2018.1531098 · Cited by 5
Pavlik, V., Chan, W., & Darby, E. J. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190661 · Cited by 5
Post-stroke Cognitive Impairment
Lim, J. (2020) · Stroke revisited · doi:10.1007/978-981-10-1433-8_2 · Cited by 5
Thyroid Hormones, Brain, and Heart
Burkauskas, J., Pranckevičienė, A., & Bunevičius, A. (2020) · Springer eBooks · doi:10.1007/978-3-030-36871-5_25 · Cited by 6
Trends of Dementia among Community-Dwelling Adults in Ontario, Canada, 2010–2015
Vanderkruk, K., Eberg, M., Mahootchi, T., Esensoy, A. V., & Seitz, D. P. (2020) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000508687 · Cited by 5
The role of lifestyle factors in primary prevention of dementia
Deckers (2017) · Research Publications (Maastricht University) · doi:10.26481/dis.20170511kd · Cited by 6
Small vessels, dementia and chronic diseases–molecular mechanisms and pathophysiology
Wardlaw, J. M., & Horsburgh, K. J. (2016) · Clinical Science · doi:10.1042/cs20160376 · Cited by 6
Goulart, T. O. (2024) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2024.tde-29102024-160742 · Cited by 5
Chaaya, M., Assaad, S., Darwish, H., Haber, M., Khoury, R., Saab, D., El Asmar, K., & Hajjar, R. (2025) · Frontiers in Dementia · doi:10.3389/frdem.2024.1494719 · Cited by 4
Nutrition, Exercise, and Cognitive Rehabilitation for Dementia Prevention
Takakura, T. (2024) · Juntendō Igaku/Juntendo igaku · doi:10.14789/jmj.jmj23-0032-r · Cited by 4
Resende, E. D. P. F., Lara, V. P., Santiago, A. L. C., Friedlaender, C. V., Rosen, H. J., Brown, J. A., Cobigo, Y., Silva, L. L. G., de Souza, L. C., Rincon, L. P., et al. (2024) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.12634 · Cited by 4
Adams, R., Leoutsakos, J., Nowrangi, M. A., Oh, E. S., Rosenberg, P. B., Skolariki, K., Yaşar, S., Zandi, P. P., & Lyketsos, C. G. (2025) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1002/trc2.70070 · Cited by 4
Regional Differences in Dementia Incidence Among US Veterans
Dintica, C. S., Bahorik, A. L., Xia, F., Boscardin, W. J., & Yaffe, K. S. (2025) · JAMA Neurology · doi:10.1001/jamaneurol.2025.1536 · Cited by 4
McGrath, E. R., Scott, M. R., Buckley, R. F., Satizábal, C. L., Werry, A. E., DeCarli, C. S., Ghosh, S., Vasan, R. S., Bhasin, S., Murabito, J. M., et al. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251372430 · Cited by 4
Self-citationLam, A. D., Johnson, E. L., Sarkis, R. A., Blank, L. J., Gaston, T. E., Shafi, M. M., Zepeda, R., Pellerin, K. R., Jetté, N., Greve, D. N., et al. (2025) · Epilepsia Open · doi:10.1002/epi4.70184 · Cited by 4
You, W., Coventry, B. J., & Henneberg, M. (2025) · Future Science OA · doi:10.1080/20565623.2025.2602336 · Cited by 5
Oye-Somefun, A., Mirzadeh, P., Gao-Kang, J., Rotondi, M. A., Kuk, J. L., Tamim, H., & Ardern, C. I. (2026) · PLoS ONE · doi:10.1371/journal.pone.0343621 · Cited by 5
Howland, R. H. (2016) · Journal of Psychosocial Nursing and Mental Health Services · doi:10.3928/02793695-20160219-04 · Cited by 4
Doblhammer, G. (2019) · AStA Wirtschafts- und Sozialstatistisches Archiv · doi:10.1007/s11943-019-00242-y · Cited by 4
Should infectious diseases be targeted to prevent dementias?
Bu, X., & Wang, Y. (2021) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(21)00258-9 · Cited by 4
Lifetime influences on imaging markers of adverse brain health and vascular disease
Backhouse, E. V., Bauermeister, S., & Wardlaw, J. M. (2023) · Cerebral Circulation - Cognition and Behavior · doi:10.1016/j.cccb.2023.100194 · Cited by 6
Alzheimer’s Disease: Engaging with an Unstable Category
Daly, T. P., & Keuck, L. (2024) · Springer eBooks · doi:10.1007/978-94-017-8706-2_113-1 · Cited by 5
Socioeconomic Disparities in Cognitive Impairment: The Role of Neighborhood Social Cohesion
Kim, Y., & Jang, S. (2025) · Innovation in Aging · doi:10.1093/geroni/igaf031 · Cited by 4
Neurocognitive Engagement Therapy
Howanitz, J., Carney, K. O., Lichtenberg, P. A., Donlan, A., Sugarman, M. A., & Malek, K. (2018) · Topics in Geriatric Rehabilitation · doi:10.1097/tgr.0000000000000172 · Cited by 4
Dementia and Intellectual Disability: Prevalence, Assessment and Post-Diagnostic Support
McGlinchey, E., Reilly, E., McCallion, P., Dunne, P., Mulryan, N., Carroll, R. E., & McCarron, M. (2019) · Autism and child psychopathology series · doi:10.1007/978-3-030-20843-1_51 · Cited by 4
Hyle, E. P., Foote, J. H. A., Shebl, F. M., Qian, Y., Reddy, K. P., Mukerji, S. S., Wattananimitgul, N., Viswanathan, A., Schwamm, L. H., Pandya, A., et al. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-056546 · Cited by 4
Sala, G., Nishita, Y., Tange, C., Tomida, M., Gondo, Y., Shimokata, H., & Otsuka, R. (2023) · Psychological Science · doi:10.1177/09567976231156793 · Cited by 4
Ding, H., Liu, C., Li, Y., Ang, T. F. A., Devine, S., Liu, Y., Au, R., & Doraiswamy, P. M. (2024) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.12569 · Cited by 4
Boongird, P., Chamnan, P., Laptikultham, S., Krittayapoositpot, P., Nitiyanant, W., Aekplakorn, W., Mangklabruks, A., & HCUR investigators (2020) · European Journal of Neurology · doi:10.1111/ene.14354 · Cited by 5
Incidence of dementia in a population cohort of older people from São Paulo, Brazil
Lopes, M. A., Nassar, S. M., Barcelos‐Ferreira, R., Folquitto, J. C., & Litvoc, J. (2021) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5660 · Cited by 6
Shirai, K., & Iso, H. (2020) · Springer series on epidemiology and public health · doi:10.1007/978-981-15-1831-7_11 · Cited by 4
Amyotrophic lateral sclerosis and richness: A correlation study across Spain
Santurtún, A., Villar, A., López-Delgado, L., & Riancho, J. (2016) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2016.06.050 · Cited by 4
Fuller‐Thomson, E., & Jopling, S. A. (2017) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2017.1074 · Cited by 4
Ikeda, S., Washida, K., Tanaka, T., Kitajima, E., Chiba, T., Fukuma, K., Yoshimoto, T., Saitô, S., Hattori, Y., & Ihara, M. (2021) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2021.105656 · Cited by 4
Epidemiology of Mental Disorders (Including Cross-Cultural Comparisons)
Kua, E. H., & Mahendran, R. (2017) · Mental health and illness worldwide · doi:10.1007/978-981-10-2414-6_5 · Cited by 4
Ashrafi, F., Taheri, M. S., Farzaneh, A., Behnam, B., & Ahmadi, M. A. (2019) · The Neuroradiology Journal · doi:10.1177/1971400919825862 · Cited by 4
Healthy ageing requires a triple strategy
Strandberg, T. E., Michel, J., & Maggi, S. (2016) · Aging Clinical and Experimental Research · doi:10.1007/s40520-016-0583-9 · Cited by 4
Direct Oral Anticoagulants and Prevention of Dementia in Nonvalvular Atrial Fibrillation
Pendlebury, S. T. (2021) · Stroke · doi:10.1161/strokeaha.121.035664 · Cited by 4
Blanco, M. N., Szpiro, A. A., Crane, P. K., & Sheppard, L. A. (2025) · Environmental Pollution · doi:10.1016/j.envpol.2025.126222 · Cited by 3
Incidence of dementia among individuals 70 years and older in Norway: A HUNT study
Molvik, I., Strand, B. H., Rokstad, A. M. M., Aakhus, E., Aam, S., Bergh, S., Brækhus, A., Engedal, K., Gjøra, L., Kjelvik, G., et al. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251371242 · Cited by 3
Huerta, J. M., Colorado-Yohar, S. M., Andreu-Reinón, M. E., Mokoroa, O., Tainta, M., Guevara, M., Gasque, A., Castilla, J., Petrova, D., Crous‐Bou, M., et al. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1671047 · Cited by 4
Yan, M., Shen, J., Zhao, M., Fei, L., Huang, Y., Wu, M., Shen, T., Hailili, G., Liu, D., Zong, G., et al. (2025) · European Journal of Epidemiology · doi:10.1007/s10654-025-01302-0 · Cited by 3
Chang, L., Liu, X., Wu, H., Yan, J., Chen, N., Li, H., Wu, W., Chen, J., & Zhang, J. (2025) · International Journal of Surgery · doi:10.1097/js9.0000000000004499 · Cited by 3
The enigma of vascular dementia: current state and emerging perspectives
Jellinger, K. A. (2026) · Journal of Neural Transmission · doi:10.1007/s00702-026-03104-4 · Cited by 3
Gupta, S. K. (2022) · PLOS Global Public Health · doi:10.1371/journal.pgph.0000579 · Cited by 3
Ostovaneh, M. R., Hughes, T. M., Wu, C. O., McClelland, R. L., Casanova, R., Bluemke, D. A., Tracy, R. P., Shea, S., Heckbert, S. R., Lima, J. A. C., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0298952 · Cited by 3
New Evidence of Healthier Aging: Positive Cohort Effects on Verbal Fluency
Massa, F., Marroig, A., Rodgers, J. L., Hofer, S. M., & Terrera, G. M. (2024) · Innovation in Aging · doi:10.1093/geroni/igae082 · Cited by 3
Decomposing Racial and Ethnic Disparities in Risk and Protective Factors of Dementia in the U.S.
Ferdows, N., & Aranda, M. (2025) · Clinical Gerontologist · doi:10.1080/07317115.2025.2534651 · Cited by 3
Regional differences in the incidence of Alzheimer’s disease and related dementias in South Carolina
Amoatika, D. A., Miller, M. C., Adams, R. J., & Milano, N. J. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1584127 · Cited by 3
The limitations of opportunistic epidemiology, pseudopod epidemiology
Kuller, L. H. (2016) · European Journal of Epidemiology · doi:10.1007/s10654-016-0196-9 · Cited by 3
Tang, J. Y. ‐., Wong, G. H. Y., Luo, H., Liu, T., & Lum, T. Y. S. (2019) · Aging & Mental Health · doi:10.1080/13607863.2019.1636204 · Cited by 3
Oumellal, A., Faris, M. E. A., & Benabdeljlil, M. (2019) · Advances in Alzheimer s Disease · doi:10.4236/aad.2019.81001 · Cited by 3
Zhang, Z., Jiang, M., Zhang, J., He, L., Li, X., Chen, Y., Lü, P., Wei, D., Guan, Q., Wang, J., et al. (2020) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/tb-2019-0535 · Cited by 3
Epidemiology of dementia onset captured in Canadian primary care electronic medical records
Pham, A. N., Voaklander, D. C., Wagg, A., & Drummond, N. (2021) · Family Practice · doi:10.1093/fampra/cmab056 · Cited by 5
Alnijadi, A. A., Li, M., Wu, J., Xiong, X., & Lu, K. (2021) · Journal of Managed Care & Specialty Pharmacy · doi:10.18553/jmcp.2022.28.1.07 · Cited by 3
Peroutka, S. J. (2022) · Contemporary Clinical Trials · doi:10.1016/j.cct.2022.106890 · Cited by 3
Kootar, S., Huque, M. H., Kiely, K. M., Anderson, C. S., Jorm, L. R., Kivipelto, M., Lautenschlager, N. T., Matthews, F. E., Shaw, J. E., Whitmer, R. A., et al. (2023) · BMJ Open · doi:10.1136/bmjopen-2023-076860 · Cited by 3
Ding, H., Kim, M., Searls, E., Sunderaraman, P., Anda‐Duran, I. D., Low, S., Popp, Z., Hwang, P. H., Li, Z., Goyal, K., et al. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1340710 · Cited by 3
Prévention des troubles cognitifs liés au vieillissement : l’apport de l’épidémiologie
Amieva, H. (2018) · Revue de neuropsychologie · doi:10.1684/nrp.2018.0453 · Cited by 3
Vire, J., Salminen, M. J., Viikari, P., Vahlberg, T. J., Arve, S., Viitanen, M. H., & Viikari, L. (2019) · Aging Clinical and Experimental Research · doi:10.1007/s40520-019-01204-8 · Cited by 3
Preventing Cognitive Decline and Dementia
Shea, Y. F., & DeKosky, S. T. (2019) · Cambridge University Press eBooks · doi:10.1017/9781108554350.019 · Cited by 4
Pour une prise en charge préventive de la maladie d’Alzheimer
Dubois, B., Bombois, S., Villain, N., Teichmann, M., Epelbaum, S., Migliaccio, R., Genthon, R., VERRAT, B., Lesoil, C., Lévy, M., et al. (2020) · Bulletin de l Académie Nationale de Médecine · doi:10.1016/j.banm.2020.04.012 · Cited by 5
Generational Differences in the 10-year Incidence of Impaired Contrast Sensitivity
Paulsen, A. J., Pinto, A. A., Fischer, M., Chen, Y., Huang, G.-H., Klein, R., Klein, R., & Cruickshanks, K. J. (2020) · Ophthalmic Epidemiology · doi:10.1080/09286586.2020.1791909 · Cited by 3
Cipollini, V., Troili, F., & Giubilei, F. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-815854-8.00002-1 · Cited by 3
Time trends in the relation between blood pressure and dementia in 85-year-olds
Ribbe, M., Kern, S., Wetterberg, H., Rydén, L., Zettergren, A., Guo, X., & Skoog, I. G. (2021) · Journal of Hypertension · doi:10.1097/hjh.0000000000002902 · Cited by 3
Ofori, M. A., Langat, A. K., Bouzir, Y., & Ishag, M. A. S. (2023) · Universal Journal of Public Health · doi:10.13189/ujph.2023.110102 · Cited by 3
Drug discovery: Chaos can be your friend or your enemy
Miller, S. M., Moos, W. H., Munk, B. H., Munk, S. A., Hart, C. P., & Spellmeyer, D. C. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-824304-6.00012-2 · Cited by 3
Prävention demenzieller Erkrankungen
Schippinger, W., & Pichler, G. (2023) · Zeitschrift für Gerontologie und Geriatrie · doi:10.1007/s00391-023-02175-2 · Cited by 3
Prevention of Cerebral Small Vessel Disease
Smith, E. E. (2017) · Seminars in Neurology · doi:10.1055/s-0037-1603468 · Cited by 3
Major or Mild Neurocognitive Disorder Due to Alzheimer Disease
Hategan, A., & Xiong, G. L. (2017) · Springer eBooks · doi:10.1007/978-3-319-67555-8_18 · Cited by 3
Population Aging: A Poor Predictor of Medicaid Expenditures
Redfoot, D. L., & Favreault, M. M. (2018) · Public Policy & Aging Report · doi:10.1093/ppar/pry012 · Cited by 3
Schooling, occupation and cognitive function: Evidence from compulsory schooling lawsPreprint
Gorman, E. (2017) · SocArXiv (OSF Preprints) · doi:10.31235/osf.io/t647a · Cited by 3
Wettstein, M., & Wahl, H. (2016) · Springer eBooks · doi:10.1007/978-981-287-080-3_109-1 · Cited by 3
Dementia Incidence on the Decline in Korea: Lessons Learned and Future Directions
Cho, S., & Kang, J. M. (2019) · Journal of Korean Medical Science · doi:10.3346/jkms.2019.34.e299 · Cited by 3
Skoog, I. G., & Madsen, T. E. (2021) · Neurology · doi:10.1212/wnl.0000000000013116 · Cited by 3
Novais, T. (2018) · theses.fr (ABES) · doi:10.70675/d907ef38zce09z4666za8a5z7eff663fff12 · Cited by 3
Park, S.-H., Choi, S.-N., Kim, J., Kim, J.-Y., & Heo, J.-H. (2023) · Journal of the Korean Neurological Association · doi:10.17340/jkna.2023.1.2 · Cited by 2
Zeyen, P., Sannemann, L., Bohr, L., Escher, C. M., Müller, T., Ramı́rez, A., Rostamzadeh, A., & Jessen, F. (2023) · Der Nervenarzt · doi:10.1007/s00115-023-01451-1 · Cited by 2
Big databases and biobanks for studying the links between CKD, cognitive impairment, and dementia
Zoccali, C., Mallamaci, F., Rosenberg, K., Unwin, R. J., Silva, P. I., Simeoni, M., Hafez, G., Capasso, G., Nitsch, D., collaborators, C. A. (. D. I. N.-N. E. C. T., et al. (2024) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfae255 · Cited by 2
Mehta, K., Morton, J. I., Salim, A., Anstey, K. J., Shaw, J. E., & Magliano, D. J. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251329458 · Cited by 2
Gupta, A., Sinha, A., Sharma, V., Raina, S., Roy, S., Baidya, S., Anand, P. K., Nehra, A., Nilima, N., Khan, M. A., et al. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-084050 · Cited by 2
Pathophysiology of Alzheimer’s Disease: Herbal Neurogenesis and Synthetic Molecular Interventions
Kumar, A., Kumar, M., Verma, A., Joshi, R., Bidlan, M., & Singh, R. (2025) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-025-00304-2 · Cited by 2
Fujihara, S., Watanabe, R., Tsuji, T., Miyaguni, Y., & Kondo, K. (2025) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2025.105944 · Cited by 2
Aortic Stiffness and Alzheimer’s Disease: The Medin Connection
Triposkiadis, F. K., Xanthopoulos, A. V., Boudoulas, H. K., & Brutsaert, D. L. (2025) · Biomolecules · doi:10.3390/biom15081148 · Cited by 2
Hickman, L. B., Pandey, B., Fish, A., Bandla, M., Husein, A., Allas, C. H., Kottakota, H., Herzog, L., Vossel, K. A., & Stern, J. M. (2025) · Epilepsia Open · doi:10.1002/epi4.70156 · Cited by 2
Alzheimer Syndrome or Age-Related Dementia—History, Therapy and Prevention
Bermejo‐Pareja, F., & del Ser, T. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14217752 · Cited by 2
Béchet, S., Leonard, M. V., Ademola, E., Fritz, J. V., & Krüger, R. (2025) · Journal of Neural Transmission · doi:10.1007/s00702-025-03090-z · Cited by 2
Metadata
- Authors
- Satizabal, C. L., Beiser, A. S., Chouraki, V., Chêne, G., Dufouil, C., & Seshadri, S.
- Affiliations
- Boston University (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2016-02-11
- Volume
- 374
- Issue
- 6
- Pages
- 523-532
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC4943081
- OpenAlex
- W2265553328
- Cited by
- 1,051
- References
- 37
- Citations by year
- 2026: 49 · 2025: 90 · 2024: 77 · 2023: 78 · 2022: 94 · 2021: 110 · 2020: 109 · 2019: 105 · 2018: 128 · 2017: 125 · 2016: 83
- FWCI
- 130.58
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (n01hc25195-41-0-1, HHSN268201500001I, N01-HC 25195)
- National Institute on Aging (P30AG010129, U01AG049505, N01-HC-25195, AG08122, R01AG054076, R01AG049607, AG033193, NS017950, R01AG033040, R01AG033193, R01AG008122)
- National Heart, Lung, and Blood Institute (N01‐HC25195, HHSN268201500001I, AG08122, HHSN268201500001C, N01-HC-025195, NS017950, AG033193)
- National Institute of Neurological Disorders and Stroke (NS017950, N01‐HC‐25195, HHSN268201500001I, R01NS017950)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
- Keywords
- dementia incidence, temporal trends, age-specific incidence, older adults, APOE ε4, educational attainment, vascular risk factors, stroke, atrial fibrillation, heart failure, cardiovascular disease, dementia risk factors
- MeSH terms
- Aged, Aged, 80 and over, Atrial Fibrillation, Dementia, Educational Status, Female, Heart Failure, Humans, Longitudinal Studies, Male, Massachusetts, Middle Aged, Risk Factors, Dementia, Vascular, Incidence, Proportional Hazards Models, Stroke
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
