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In Search of a Better Equation — Performance and Equity in Estimates of Kidney Function
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In Search of a Better Equation Although many experts agree that we should reconsider the use of race in equations for estimated glomerular filtration rate and in medicine more generally, precisely ...
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“thus providing empirical genetic evidence to the observation that eGFR models have reduced performance in individuals self-identifying as Black or African American.45”
From Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy (2023) · cites this paper as [45]
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“For reasons that cannot be ruled out as environmental or a product of care, Black patients are noted to often have higher creatinine levels than White patients with the same level of kidney function (Diao et al., 2021).”
From On race, human variation, and who gets and dies of sepsis (2022) · cites this paper as Diao et al., 2021
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Metadata
- Authors
- Diao, J. A., Inker, L. A., Levey, A. S., Tighiouart, H., Powe, N. R., & Manrai, A. K.
- Affiliations
- Boston Children's Hospital (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2021-02-04
- Volume
- 384
- Issue
- 5
- Pages
- 396-399
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC8084706
- OpenAlex
- W3121110988
- Cited by
- 115
- References
- 5
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 12 · 2023: 27 · 2022: 32 · 2021: 33
- FWCI
- 17.98
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (K01HL138259)
- Topics
- Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
- Social Sciences › Anthropology › Race, Genetics, and Society
- Health Sciences › Health Professions › Medical Laboratory Technology › Clinical Laboratory Practices and Quality Control
- Keywords
- estimated glomerular filtration rate, renal function, chronic kidney disease, racial disparities in health care
- MeSH terms
- Female, Glomerular Filtration Rate, Humans, Kidney, Kidney Function Tests, Male, Reference Values, Racial Groups
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