Chronic Constipation

A new method for studying gut transit times using radioopaque markers

Hinton, J., Lennard‐Jones, J. E., & Young, A. C. (1969) · Gut · doi:10.1136/gut.10.10.842 · Cited by 838 · see citing works

Defecation frequency and timing, and stool form in the general population: a prospective study.

Heaton, K. W., Radvan, J., Cripps, H., Mountford, R. A., Braddon, F. E., & Hughes, A. O. (1992) · Gut · doi:10.1136/gut.33.6.818 · Cited by 733 · see citing works

The Rectovaginal Septum Revisited: Its Relationship to Rectocele and Its Importance in Rectocele Repair

RICHARDSON, A. C. (1993) · Clinical Obstetrics & Gynecology · doi:10.1097/00003081-199312000-00022 · Cited by 718 · see citing works

Neostigmine for the Treatment of Acute Colonic Pseudo-Obstruction

Ponec, R. J., Saunders, M. D., & Kimmey, M. B. (1999) · New England Journal of Medicine · doi:10.1056/nejm199907153410301 · Cited by 613 · see citing works

One-Time Screening for Colorectal Cancer with Combined Fecal Occult-Blood Testing and Examination of the Distal Colon

Lieberman, D. A., Harford, W. V., Ahnen, D. J., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa010328 · Cited by 584 · see citing works

Epidemiology of Constipation (EPOC) Study in The United States: Relation of Clinical Subtypes to Sociodemographic Features

Stewart, W. F., Liberman, J. N., Sandler, R. S., Woods, M. S., Stemhagen, A., Chee, E. M., Lipton, R. B., & Farup, C. E. (1999) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1999.01642.x · Cited by 490 · see citing works

Tegaserod, a 5‐HT4 receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation

Müller-Lissner, S. A., Fumagalli, I. A. L., Bardhan, K. D., Pace, F., Pecher, E., Nault, B., & Rüegg, P. C. (2001) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2001.01094.x · Cited by 462 · see citing works

An epidemiological survey of constipation in Canada: definitions, rates, demographics, and predictors of health care seeking

Paré, P., Ferrazzi, S., Thompson, W., Irvine, E. J., & Rance, L. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.05259.x · Cited by 445 · see citing works

AGA technical review on anorectal testing techniques.

Diamant, N., Kamm, M., Wald, A., & Whitehead, W. (1999) · Gastroenterology · doi:10.1016/s0016-5085(99)70195-2 · Cited by 408 · see citing works

Decreased interstitial cell of Cajal volume in patients with slow-transit constipation

He, C., Burgart, L. J., Wang, L., Pembérton, J. H., Young‐Fadok, T. M., Szurszewski, J. H., & Farrugia, G. (2000) · Gastroenterology · doi:10.1016/s0016-5085(00)70409-4 · Cited by 407 · see citing works

Severe chronic constipation of young women: 'idiopathic slow transit constipation'.

Preston, D. M., & Lennard‐Jones, J. E. (1986) · Gut · doi:10.1136/gut.27.1.41 · Cited by 402 · see citing works

A longitudinal survey of self-reported bowel habits in the United States

Everhart, J. E., Go, V. L. W., Johannes, R. S., FitzSimmons, S. C., Roth, H. P., & White, L. R. (1989) · Digestive Diseases and Sciences · doi:10.1007/bf01537261 · Cited by 384 · see citing works

Obstructive Defecation: A Failure of Rectoanal Coordination

Rao, S. S. C., Welcher, K., & Leistikow, J. (1998) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1998.00326.x · Cited by 364 · see citing works

5-Hydroxytryptamine4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine

Grider, J. R., Foxx–Orenstein, A. E., & Jin, J. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70203-3 · Cited by 349 · see citing works

Physician visits in the United States for constipation: 1958 to 1986

Sonnenberg, A., & Koch, T. R. (1989) · Digestive Diseases and Sciences · doi:10.1007/bf01536339 · Cited by 321 · see citing works

Scintigraphic measurement of regional gut transit in idiopathic constipation.

Stivland, T., Camilleri, M., Vassallo, M., Proano, M., Rath, D. M., Brown, M. L., Thomforde, G., Pemberton, J., & Phillips, S. (1991) · Gastroenterology · doi:10.1016/0016-5085(91)90466-x · Cited by 272 · see citing works

Long-term results of surgery for chronic constipation

Nyam, D., Pemberton, J., Ilstrup, D., & Rath, D. M. (1997) · Diseases of the Colon & Rectum · doi:10.1007/bf02050415 · Cited by 255 · see citing works

Biofeedback training in disordered defecation

Enck, P. (1993) · Digestive Diseases and Sciences · doi:10.1007/bf01297069 · Cited by 239 · see citing works

Bowel habits in young adults not seeking health care

Sandler, R. S., & Drossman, D. A. (1987) · Digestive Diseases and Sciences · doi:10.1007/bf01296706 · Cited by 233 · see citing works

Clinical Epidemiology of Chronic Constipation

Johanson, J. F., Sonnenberg, A., & Koch, T. R. (1989) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-198910000-00008 · Cited by 232 · see citing works

Outcome of Colectomy for Slow Transit Constipation

Knowles, C. H., Scott, S. M., & Lunniss, P. J. (1999) · Annals of Surgery · doi:10.1097/00000658-199911000-00004 · Cited by 228 · see citing works

How well does stool form reflect colonic transit?

Degen, L., & Phillips, S. (1996) · Gut · doi:10.1136/gut.39.1.109 · Cited by 201 · see citing works

Symptoms in chronic constipation

Koch, A. H., Voderholzer, W. A., Klauser, A. G., & Müller-Lissner, S. A. (1997) · Diseases of the Colon & Rectum · doi:10.1007/bf02051196 · Cited by 184 · see citing works

Review article: anthranoid laxatives and their potential carcinogenic effects

van Gorkom, B. A. P., de Vries, E. G. E., Karrenbeld, & KLEIBEUKER (1999) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.1999.00468.x · Cited by 172 · see citing works

Physiology of Refractory Chronic Constipation

Mertz, H., Naliboff, B. D., & Mayer, E. A. (1999) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1999.922_a.x · Cited by 154 · see citing works

Endo-rectal repair of rectocele

Sarles, J. C., Arnaud, A., Selezneff, I., et al. (1989) · International Journal of Colorectal Disease · doi:10.1007/bf01649696 · Cited by 138 · see citing works

Small volume isosmotic polyethylene glycol electrolyte balanced solution (PMF-100) in treatment of chronic nonorganic constipation

Corazziari, E., Badiali, D., Habib, F. I., Reboa, G., Pitto, G., Mazzacca, G., Sabbatini, F., Galeazzi, R., Cilluffo, T., Vantini, I., et al. (1996) · Digestive Diseases and Sciences · doi:10.1007/bf02087913 · Cited by 135 · see citing works

Clinical Management of Intractable Constipation

Camilleri, M., Thompson, W. G., Fleshman, J. W., & Pemberton, J. H. (1994) · Annals of Internal Medicine · doi:10.7326/0003-4819-121-7-199410010-00008 · Cited by 135 · see citing works

Nitric oxide synthase and VIP distribution in enteric nervous system in idiopathic chronic constipation

Cortesini, C., Cianchi, F., Infantino, A., & Lise, M. (1995) · Digestive Diseases and Sciences · doi:10.1007/bf02063253 · Cited by 132 · see citing works

ENCOPRESIS AND SOILING

Loening-Baucke, V. A. (1996) · Pediatric Clinics of North America · doi:10.1016/s0031-3955(05)70406-5 · Cited by 128 · see citing works

Controlled randomised trial of visual biofeedback versus muscle training without a visual display for intractable constipation.

Koutsomanis, D., Lennard‐Jones, J. E., Roy, A. J., et al. (1995) · Gut · doi:10.1136/gut.37.1.95 · Cited by 128 · see citing works

Fecal Impaction

Desforges, J. F., & Wrenn, K. (1989) · New England Journal of Medicine · doi:10.1056/nejm198909073211007 · Cited by 128 · see citing works

Effects of Regular Exercise in Management of Chronic Idiopathic Constipation

Meshkinpour, H., Selod, S., Movahedi, H., Nami, N., James, N., & Wilson, A. (1998) · Digestive Diseases and Sciences · doi:10.1023/a:1026609610466 · Cited by 124 · see citing works

Descending Perineum Syndrome: Audit of Clinical and Laboratory Features and Outcome of Pelvic Floor Retraining

Harewood, G. C., Coulie, B. J., Camilleri, M., et al. (1999) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1999.00782.x · Cited by 121 · see citing works

Botulinum toxin type-a in therapy of patients with anismus

Ron, Y., Avni, Y., Lukovetski, A., Wardi, J., Geva, D., Birkenfeld, S., & Halpern, Z. (2001) · Diseases of the Colon & Rectum · doi:10.1007/bf02234461 · Cited by 119 · see citing works

Hirschsprung's disease and idiopathic megacolon in adults and adolescents.

Barnes, P. R. H., Lennard‐Jones, J. E., Hawley, P. R., et al. (1986) · Gut · doi:10.1136/gut.27.5.534 · Cited by 119 · see citing works

Decreased substance P levels in rectal biopsies from patients with slow transit constipation

Tzavella, K., Riepl, R. L., Klauser, A. G., Voderholzer, W. A., Schindlbeck, N. E., & ller-Lissner, S. A. M. U. (1996) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-199612000-00014 · Cited by 109 · see citing works

Impaired colonic motor response to cholinergic stimulation in patients with severe chronic idiopathic (slow transit type) constipation

Bassotti, G., Chiarioni, G., Imbimbo, B. P., et al. (1993) · Digestive Diseases and Sciences · doi:10.1007/bf01295719 · Cited by 99 · see citing works

Increasing Oral Fluids in Chronic Constipation in Children

Young, R. J., Beerman, L., & Vanderhoof, J. A. (1998) · Gastroenterology Nursing · doi:10.1097/00001610-199807000-00002 · Cited by 96 · see citing works

Balloon expulsion test facilitates diagnosis of pelvic floor outlet obstruction due to nonrelaxing puborectalis muscle

Fleshman, J. W., Dreznik, Z., Cohen, E., et al. (1992) · Diseases of the Colon & Rectum · doi:10.1007/bf02252990 · Cited by 91 · see citing works

Melanosis of the rectum in patients with chronic constipation

Badiali, D., Marcheggiano, A., Pallone, F., et al. (1985) · Diseases of the Colon & Rectum · doi:10.1007/bf02554044 · Cited by 88 · see citing works

Parameters of anorectal and colonic motility in health and in severe constipation

Pezim, M., Pemberton, J., Levin, K., Litchy, W., & Phillips, S. (1993) · Diseases of the Colon & Rectum · doi:10.1007/bf02050015 · Cited by 87 · see citing works

Misoprostol in the treatment of chronic refractory constipation: results of a long‐term open label trial

Roarty, T., Weber, F., Soykan, I., & McCallum, R. (1997) · Alimentary Pharmacology and Therapeutics · doi:10.1046/j.1365-2036.1997.00237.x · Cited by 75 · see citing works

Behavioral modification of colonic function

Klauser, A., Voderholzer, W., Heinrich, C., Schindlbeck, N., & Müller-Lissner, S. (1990) · Digestive Diseases and Sciences · doi:10.1007/bf01536418 · Cited by 75 · see citing works

The use of bethanechol chloride with tricyclic antidepressants

Everett, H. C. (1975) · American Journal of Psychiatry · doi:10.1176/ajp.132.11.1202 · Cited by 69 · see citing works

Long segment and short segment familial Hirschsprung's disease: variable clinical expression at the RET locus.

Edery, P., Pelet, A., Mulligan, L. M., et al. (1994) · Journal of Medical Genetics · doi:10.1136/jmg.31.8.602 · Cited by 61 · see citing works

FECOM: A New Artificial Stool for Evaluating Defecation

Pelsang, R. E., Rao, S. S. C., & Welcher, K. (1999) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1999.00793.x · Cited by 45 · see citing works

Is bisacodyl absorbed at all from suppositories in man?

Flig, E., Hermann, T., & Zabel, M. (2000) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(99)00385-3 · Cited by 39 · see citing works

Colchicine Is an Effective Treatment for Patients with Chronic Constipation (An Open-Label Trial)

Verne, G., Eaker, E., Davis, R. H., & Sninsky, C. (1997) · Digestive Diseases and Sciences · doi:10.1023/a:1018883731556 · Cited by 38 · see citing works

ABC of colorectal diseases. Paediatric problems--I.

Doig, C. M. (1992) · BMJ · doi:10.1136/bmj.305.6851.462 · Cited by 9 · see citing works

Raising the bar

Young‐Fadok, T. M. (2001) · Surgical Endoscopy · doi:10.1007/s00464-001-0057-8 · Cited by 8 · see citing works

Functional Bowel Disorders

Longstreth, G. F., Thompson, W. G., Chey, W. D., Houghton, L. A., Mearin, F., & Spiller, R. C. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.061 · Cited by 4,856 · see citing works

Gut/brain axis and the microbiota

Mayer, E. A., Tillisch, K., & Gupta, A. (2015) · Journal of Clinical Investigation · doi:10.1172/jci76304 · Cited by 1,503 · see citing works

Principles and clinical implications of the brain-gut-enteric microbiota axis

Rhee, S. H., Pothoulakis, C., & Mayer, E. A. (2009) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2009.35 · Cited by 1,342 · see citing works

Chronic constipation: a survey of the patient perspective

JOHANSON, J. F., & KRALSTEIN, J. (2007) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.03238.x · Cited by 617 · see citing works

A placebo-controlled trial of prucalopride for severe chronic constipation

Camilleri, M., Kerstens, R., Rykx, A., & Vandeplassche, L. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0800670 · Cited by 576 · see citing works

Brain gut microbiome interactions and functional bowel disorders

Mayer, E. A., Savidge, T., & Shulman, R. J. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.02.037 · Cited by 496 · see citing works

Two randomized trials of linaclotide for chronic constipation

Lembo, A. J., Schneier, H. A., Shiff, S. J., Kurtz, C. B., MacDougall, J. E., Jia, X. D., Shao, J. Z., Lavins, B. J., Currie, M. G., Fitch, D. A., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1010863 · Cited by 373 · see citing works

Association of low dietary intake of fiber and liquids with constipation: Evidence from the National Health and Nutrition Examination Survey

Markland, A. D., Palsson, O., Goode, P. S., Burgio, K. L., Busby-Whitehead, J., & Whitehead, W. E. (2013) · American Journal of Gastroenterology · doi:10.1038/ajg.2013.73 · Cited by 254 · see citing works

Potential role of fecal microbiota from patients with slow transit constipation in the regulation of gastrointestinal motility

Ge, X., Zhao, W., Ding, C., Tian, H., Xu, L., Wang, H., Ni, L., Jiang, J., Gong, J., Zhu, W., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-00612-y · Cited by 232 · see citing works

European society of neurogastroenterology and motility guidelines on functional constipation in adults

Serra, J., Pohl, D., Azpiroz, F., Chiarioni, G., Ducrotté, P., Gourcerol, G., Hungin, A. P. S., Layer, P., Mendive, J., Pfeifer, J., et al. (2020) · Neurogastroenterology & Motility · doi:10.1111/nmo.13762 · Cited by 244 · see citing works

Basics of autonomic nervous system function

(2019) · Handbook of Clinical Neurology · doi:10.1016/b978-0-444-64032-1.00027-8 · Cited by 233 · see citing works

Probiotics for Constipation in Parkinson Disease: A Randomized Placebo-Controlled Study

Tan, A. H., Lim, S.-Y., Chong, K. K., A Manap, M. A. A., Hor, J. W., Lim, J. L., Low, S. C., Chong, C. W., Mahadeva, S., & Lang, A. E. (2021) · Neurology · doi:10.1212/wnl.0000000000010998 · Cited by 226 · see citing works

A randomized, multicenter, placebo-controlled trial of polyethylene glycol laxative for chronic treatment of chronic constipation

DiPalma, J. A., Cleveland, M. V., McGowan, J., & Herrera, J. L. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01199.x · Cited by 217 · see citing works

Randomized Clinical Trial: Macrogol/PEG 3350 Plus Electrolytes for Treatment of Patients With Constipation Associated With Irritable Bowel Syndrome

Chapman, R. W., Stanghellini, V, Geraint, M., & Halphen, M. (2013) · American Journal of Gastroenterology · doi:10.1038/ajg.2013.197 · Cited by 180 · see citing works

Effect of a fermented milk containing Bifidobacterium lactis DN-173010 on Chinese constipated women

Yang, Y.-X., He, M., Hu, G., Wei, J., Pages, P., Yang, X.-H., & Bourdu-Naturel, S. (2008) · World Journal of Gastroenterology · doi:10.3748/wjg.14.6237 · Cited by 151 · see citing works

Effect of yogurt containing polydextrose, Lactobacillus acidophilus NCFM and Bifidobacterium lactis HN019: A randomized, double-blind, controlled study in chronic constipation

Magro, D. O., de Oliveira, L. M. R., Bernasconi, I., de Souza Ruela, M., Credidio, L., Barcelos, I. K., Leal, R. F., Ayrizono, M. D. L. S., Fagundes, J. J., Teixeira, L. D. B., et al. (2014) · Nutrition Journal · doi:10.1186/1475-2891-13-75 · Cited by 105 · see citing works

Phenotypic Variation of Colonic Motor Functions in Chronic Constipation

Ravi, K., Bharucha, A. E., Camilleri, M., Rhoten, D., Bakken, T., & Zinsmeister, A. R. (2010) · Gastroenterology · doi:10.1053/j.gastro.2009.07.057 · Cited by 92 · see citing works

Elobixibat and its potential role in chronic idiopathic constipation

Acosta, A., & Camilleri, M. (2014) · Therapeutic Advances in Gastroenterology · doi:10.1177/1756283x14528269 · Cited by 91 · see citing works

A randomized, multicenter comparison of polyethylene glycol laxative and tegaserod in treatment of patients with chronic constipation

Di Palma, J. A., Cleveland, M. V., McGowan, J., & Herrera, J. L. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01365.x · Cited by 84 · see citing works

Randomised clinical trial: macrogol/ <scp>PEG</scp> 3350+electrolytes versus prucalopride in the treatment of chronic constipation ‐ a comparison in a controlled environment

Cinca, R., Chera, D., Gruss, H. ‐., & Halphen, M. (2013) · Alimentary Pharmacology &amp; Therapeutics · doi:10.1111/apt.12278 · Cited by 73 · see citing works

The economic burden of treatment failure amongst patients with irritable bowel syndrome with constipation or chronic constipation: a retrospective analysis of a Medicaid population

Guerin, A., Carson, R. T., Lewis, B., Yin, D., Kaminsky, M., & Wu, E. (2014) · Journal of Medical Economics · doi:10.3111/13696998.2014.919926 · Cited by 71 · see citing works

Outcomes and prognostic factors of fecal microbiota transplantation in patients with slow transit constipation: results from a prospective study with long-term follow-up

Ding, C., Fan, W., Gu, L., Tian, H., Ge, X., Gong, J., Nie, Y., & Li, N. (2018) · Gastroenterology report · doi:10.1093/gastro/gox036 · Cited by 65 · see citing works

Nutritional care of the patient with constipation

Fernández-Bañares, F. (2006) · Best Practice &amp; Research Clinical Gastroenterology · doi:10.1016/j.bpg.2005.11.002 · Cited by 65 · see citing works

Gut microbial and short-chain fatty acid profiles in adults with chronic constipation before and after treatment with lubiprostone

Kang, D.-W., DiBaise, J. K., Ilhan, Z. E., Crowell, M. D., Rideout, J. R., Caporaso, J. G., Rittmann, B. E., & Krajmalnik-Brown, R. (2015) · Anaerobe · doi:10.1016/j.anaerobe.2015.01.005 · Cited by 55 · see citing works

Effects of Fructo-Oligosaccharide Supplementation on Constipation in Elderly Continuous Ambulatory Peritoneal Dialysis Patients

Meksawan, K., Chaotrakul, C., Leeaphorn, N., Gonlchanvit, S., Eiam-Ong, S., & Kanjanabuch, T. (2016) · Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis · doi:10.3747/pdi.2014.00015 · Cited by 54 · see citing works

Effect of Lactobacillus casei Shirota on colonic transit time in patients with chronic constipation

Krammer, H.-J., von Seggern, H., Schaumburg, J., & Neumer, F. (2011) · coloproctology · doi:10.1007/s00053-011-0177-0 · Cited by 54 · see citing works

A randomized double-blind placebo-controlled trial on the effect of magnesium oxide in patients with chronic constipation

Mori, S., Tomita, T., Fujimura, K., Asano, H., Ogawa, T., Yamasaki, T., Kondo, T., Kono, T., Tozawa, K., Oshima, T., et al. (2019) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm18194 · Cited by 47 · see citing works

Current Management of Chronic Constipation in Japan

Masaoka, T. (2023) · The Keio Journal of Medicine · doi:10.2302/kjm.2022-0036-ir · Cited by 7 · see citing works

Rectocele repair in women with obstructed defecation

van Dam, J. H. (1999)

IMPACT OF DEFECATION TIME AND FREQUENCY ON ELDERLY CONSTIPATION

Li, J. (2009) · Xiandai yufang yixue

Paediatric constipation for adult surgeons − article 2: new microscopic abnormalities and therapies

King, S. K., Sutcliffe, J., Hutson, J. M., et al. (2004) · ANZ Journal of Surgery · doi:10.1111/j.1445-1433.2004.03202.x · Cited by 8 · see citing works

The impact of chronic constipation in adults

Dowden, A. (2021) · Prescriber · doi:10.1002/psb.1954 · Cited by 1 · see citing works