Cited by 1,621Asthma and respiratory diseasesAir Quality and Health ImpactsOccupational exposure and asthma

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The Asthma Epidemic

Eder, Waltraud, Ege, Markus J., von Mutius, Erika·2006·New England Journal of Medicine

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Abstract

This review surveys the data on the increase in the prevalence of asthma in recent decades and finds evidence of a plateau in many Western countries. The authors examine the evidence of possible causal relations to factors such as air pollution, obesity, diet, and exposure to infections, antibiotics, and allergens, including exposures at very young ages. The most strongly supported preventive measure is the avoidance of passive and active exposure to smoke.

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Crossref · 10.1056/nejmra054308

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Hilty, M., Burke, C. M., Pedro, H., Cárdenas, P., Bush, A., Bossley, C. J., Davies, J. C., Ervine, A., Poulter, L. W., Pachter, L. S., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008578 · Cited by 1,874
Allergenic pollen and pollen allergy in Europe.
D’Amato, G., Cecchi, L., Bonini, S., Nunes, C., Annesi‐Maesano, I., Behrendt, H., Liccardi, G., Popov, T., & Van Cauwenberge, P. (2007) · Allergy · doi:10.1111/j.1398-9995.2007.01393.x · Cited by 1,342
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See all 1,621

Authors: Eder, W., Ege, M. J., & von Mutius, E.
Affiliations: Ludwig-Maximilians-Universität München (DE)
ORCID: Ege, Markus J.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2006-11-23
Volume: 355
Issue: 21
Pages: 2226-2235
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmra054308
OpenAlex: W2081375496
Cited by: 1,621
References: 99
Citations by year: 2026: 13 · 2025: 29 · 2024: 35 · 2023: 59 · 2022: 57 · 2021: 83 · 2020: 61 · 2019: 69 · 2018: 85 · 2017: 82 · 2016: 93 · 2015: 119 · 2014: 122 · 2013: 118 · 2012: 129
FWCI: 10.23
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
Keywords: asthma, asthma prevalence, asthma epidemic, air pollution, obesity, diet, infection exposure, antibiotic exposure, allergen exposure, early life exposure, passive smoking, active smoking, asthma prevention
MeSH terms: Air Pollution, Allergens, Asthma, Bacteria, Diet, Humans, Hypersensitivity, Immediate, Infections, Tobacco Smoke Pollution, Causality, Prevalence, Bronchial Hyperreactivity

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