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Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection
Open accessAbstract
During the spring of 2009, a novel influenza A (H1N1) virus of swine origin caused human infection and acute respiratory illness in Mexico.1,2 After initially spreading among persons in the United States and Canada,3,4 the virus spread globally, resulting in the first influenza pandemic since 1968 with circulation outside the usual influenza season in the Northern Hemisphere (see the Supplementary Appendix, available with the full text of this article at NEJM.org). As of March 2010, almost all countries had reported cases, and more than 17,700 deaths among laboratory-confirmed cases had been reported to the World Health Organization (WHO).5 The number of laboratory-confirmed cases significantly underestimates the pandemic's impact. In the United States, an estimated 59 million illnesses, 265,000 hospitalizations, and 12,000 deaths had been caused by the 2009 H1N1 virus as of mid-February 2010.6 This article reviews virologic, epidemiologic, and clinical data on 2009 H1N1 virus infections and summarizes key issues for clinicians worldwide.
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Cites
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Critically Ill Patients With 2009 Influenza A(H1N1) Infection in Canada
Kumar, A. (2009) · JAMA · doi:10.1001/jama.2009.1496 · Cited by 1,425
Pneumonia and Respiratory Failure from Swine-Origin Influenza A (H1N1) in Mexico
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Cited by
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Probable airborne transmission of SARS-CoV-2 in a poorly ventilated restaurant
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Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
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Influenza virus-related critical illness: pathophysiology and epidemiology
Kalil, A. C., & Thomas, P. G. (2019) · Critical Care · doi:10.1186/s13054-019-2539-x · Cited by 524
Metadata
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2010-05-06
- Volume
- 362
- Issue
- 18
- Pages
- 1708-1719
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2508794604
- Cited by
- 1,062
- References
- 6
- FWCI
- 120.56
- Type
- journal article
- Language
- en
- Open access
- bronze
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